ZDHHC8 Gene

Aliases
for ZDHHC8 gene

Previous GC identifers: GC22P017059 GC22P018494 GC22P018493 GC22P018499 GC22P003740

Summaries
for ZDHHC8 gene

Genomic Views
for ZDHHC8 gene

RefSeq DNA sequence:

NC_000022.10  NC_018933.1  NT_011519.10  

SwitchGear Promoter luciferase reporter plasmid: ZDHHC8 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZDHHC8

ZDHHC8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P020116:  view genomic region     (about GC identifiers)

Proteins
for ZDHHC8 gene

Explore the universe of human proteins at neXtProt for ZDHHC8: NX_Q9ULC8

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: ZDHHC8 OriGene Custom Protein Services for ZDHHC8
	GenScript Custom Purified and Recombinant Proteins Services for ZDHHC8
	Novus Biologicals ZDHHC8 Protein Novus Biologicals ZDHHC8 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ZDHHC8

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of ZDHHC8
	Browse R&D Systems for Antibodies
	OriGene Antibodies: ZDHHC8 OriGene Custom Antibody Services for ZDHHC8
	GenScript Custom Superior Antibodies Services for ZDHHC8
	Novus Biologicals ZDHHC8 Antibodies
	Search for Antibodies for ZDHHC8 at Abcam
	Uscn Antibodies for ZDHHC8
	ThermoFisher Antibodies for ZDHHC8

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZDHHC8
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ZDHHC8

Protein Domains /
Families
for ZDHHC8 gene

ProtoNet protein and cluster: Q9ULC8

Function
for ZDHHC8 gene

Enzyme Numbers (IUBMB): EC 2.3.1² EC 2.3.1.-¹

miRNA Products:		OriGene 3'-UTR Clone: ZDHHC8 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZDHHC8
		8/55 QIAGEN miScript miRNA Assays for microRNAs that regulate ZDHHC8 (see all 55):
		hsa-miR-576-3p hsa-miR-21* hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-1258 hsa-miR-488
		SwitchGear 3'UTR luciferase reporter plasmid: ZDHHC8 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZDHHC8 (see all 7) OriGene shRNA RFP: ZDHHC8 OriGene siRNA: ZDHHC8
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZDHHC8

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for ZDHHC8

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZDHHC8 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZDHHC8 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): ZDHHC8 (NM_013373)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC8

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ZDHHC8
		Search LifeMap BioReagents cell lines for ZDHHC8

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC8

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

(inferred from 2 alleles) (MGI details for Zdhhc8)

Pathways & Interactions
for ZDHHC8 gene

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

Drugs & Compounds
for ZDHHC8 gene

Transcripts
for ZDHHC8 gene

Expression
for ZDHHC8 gene

ZDHHC8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAGCGTCTG

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Neural TubeTelencephalon			Neural Tube
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZDHHC8 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZDHHC8
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC8
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZDHHC8

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC8

Orthologs
for ZDHHC8 gene

Paralogs
for ZDHHC8 gene

Paralogs for ZDHHC8 gene

ZDHHC14²  ZDHHC5²  ZDHHC12²  ZDHHC19²  ZDHHC18²  ZDHHC9²  

6 SIMAP similar genes for ZDHHC8 using alignment to 3 protein entries:     ZDHC8_HUMAN (see all proteins):

ZDHHC5    ZDHHC18    ZDHHC9    ZDHHC2    ZDHHC14    ZDHHC19

ZDHHC8 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for ZDHHC8
PGOHUM00000246279

Genomic Variants
for ZDHHC8 gene

10/318 NCBI SNPs in ZDHHC8 are shown (see all 318)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs412814351,2		--	3738370(+)	TGGGTC/GGCAGA	2	--	us2k1		0	--	--	--	--
rs412814371,2	F,	--	3739004(+)	GGCCTG/CCAGGC	2	--	us2k1		1		NA	120
rs412814391,2	F,	--	3739102(+)	TGAGGT/CCCCCC	2	--	us2k1		1		NA	120
rs59939191,2	C	--	3739112(+)	CCACAG/AATCTC	2	--	us2k1		1		NA	2
rs59939201,2	C	--	3739124(+)	ACCTAA/GGGAGG	2	--	us2k1		0	--	--	--	--
rs1131188381,2		--	3739566(+)	GGCGGT/CCAGAA	2	--	us2k1		2		CSA WA	119
rs769721281,2	F,	--	3739654(+)	TCGTTA/GGGGAA	2	--	us2k1		1		EA	120
rs96062581,2	C,	--	3740325(+)	ATGGCA/GGTCCC	2	--	int1		2		NA	122
rs773043851,2	F,	--	3740497(+)	CTGCCC/ATGGGT	2	--	int1		1		WA	118
rs1997701671,2	C	--	3740972(+)	GGCTGG/TGGGGT	2	--	int1		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZDHHC8 (20116979 - 20135530 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZDHHC8
     3 CNVs: 30155 4117 31071
Human Gene Mutation Database (HGMD): ZDHHC8

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZDHHC8

DNA2.0 Custom Variant and Variant Library Synthesis for ZDHHC8

Disorders / Diseases
for ZDHHC8 gene

Publications
for ZDHHC8 gene

PubMed articles for ZDHHC8 gene, integrated from 9 sources (see all 27): (articles sorted by number of sources associating them with ZDHHC8)

Utopia: connect your pdf to the dynamic world of online information

1. Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. (PubMed id 15184899)^{1, 2, 3, 4} Mukai J....Gogos J.A. (2004)
2. Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8. (PubMed id 15489219)^{1, 2, 4, 9} Chen W.-Y.... He L. (2004)
3. No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples. (PubMed id 15992527)^{1, 2, 4, 9} Glaser B.... Owen M.J. (2005)
4. The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia. (PubMed id 16150541)^{1, 2, 4} Otani K.... Kuroda S. (2005)
5. No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population. (PubMed id 15631889)^{1, 2, 4} Saito S.... Ozaki N. (2005)
6. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)^{1, 2, 3} Nagase T.... Ohara O. (1999)
7. ZDHHC8 as a candidate gene for schizophrenia: analysis of a putative functional intronic marker in case-control and family-based association studies. (PubMed id 16225675)^{1, 4, 9} Faul T....Stober G. (2005)
8. Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function. (PubMed id 19556522)^{1, 2} Singaraja R.R....Hayden M.R. (2009)
9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)

External Searches for ZDHHC8 gene

Genome Databases showing ZDHHC8 gene

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Products
for ZDHHC8 gene