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ZDHHC7 Gene

protein-coding   GIFtS: 53
GCID: GC16M085007

Zinc Finger, DHHC-Type Containing 7

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger, DHHC-Type Containing 71 2     SERZ-B2
Zinc Finger DHHC Domain-Containing Protein 72 3     SERZ12
Zinc Finger Protein 3702 3     Palmitoyltransferase ZDHHC72
DHHC-72 3     Sertoli Cell Gene With Zinc Finger Domain-β2
ZNF3702 3     Zinc Finger, DHHC Domain Containing 72
DHHC72 5     EC 2.3.1.2253
Sertoli Cell Gene With Zinc Finger Domain-β1     EC 2.3.18

External Ids:    HGNC: 184591   Entrez Gene: 556252   Ensembl: ENSG000001537867   OMIM: 6146045   UniProtKB: Q9NXF83   
ORGUL members:         

Export aliases for ZDHHC7 gene to outside databases

Previous GC identifers: GC16M075554 GC16M085974 GC16M084746 GC16M084787 GC16M083565 GC16M070760


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZDHHC7 Gene:
ZDHHC7 (zinc finger, DHHC-type containing 7) is a protein-coding gene. GO annotations related to this gene include palmitoyltransferase activity. An important paralog of this gene is ZDHHC21.

UniProtKB/Swiss-Prot: ZDHC7_HUMAN, Q9NXF8
Function: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA
receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering
and/or cell surface stability (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR
and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by
sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their
nuclear receptors




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC7 gene promoter:
         ER-alpha   JunB   Bach2   Pax-2   Olf-1   Pax-2a   JunD   Nkx6-1   HOXA5   TGIF   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZDHHC7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.1   Ensembl cytogenetic band:  16q24.1   HGNC cytogenetic band: 16q23.1

ZDHHC7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC7 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M085007:  view genomic region     (about GC identifiers)

Start:
85,007,787 bp from pter      End:
85,045,141 bp from pter
Size:
37,355 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZDHC7_HUMAN, Q9NXF8 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC7  
Size: 308 amino acids; 35140 Da
Sequence caution: Sequence=AAH17702.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA91814.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: D3DUM1 Q8WV42 Q9NVD8
Alternative splicing: 2 isoforms:  Q9NXF8-1   Q9NXF8-2   

Explore the universe of human proteins at neXtProt for ZDHHC7: NX_Q9NXF8

Explore proteomics data for ZDHHC7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for ZDHHC7 (Q9NXF8)
     MDHHCPW  WFIRDGCG  FVLFTMYIAL  MLTDPGAVPKGNATKE 


    See ZDHHC7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139020.1  NP_060210.2  

    ENSEMBL proteins: 
     ENSP00000315604   ENSP00000341681   ENSP00000456782   ENSP00000454965   ENSP00000454390  

    ZDHHC7 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZDHHC7

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q9NXF8

    ProtoNet protein and cluster: Q9NXF8

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDHC7_HUMAN, Q9NXF8
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDHC7_HUMAN, Q9NXF8
    Function: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA
    receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering
    and/or cell surface stability (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR
    and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by
    sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their
    nuclear receptors
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    Find genes that share ontologies with ZDHHC7           About GenesLikeMe


    Animal Models:
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    miRTarBase miRNAs that target ZDHHC7:
    hsa-mir-1229-3p (MIRT036367), hsa-mir-615-3p (MIRT039953), hsa-mir-26b-5p (MIRT028769), hsa-mir-877-3p (MIRT037109)

    Block miRNA regulation of human, mouse, rat ZDHHC7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC7 (see all 55):
    hsa-miR-3164 hsa-miR-376b hsa-miR-146a hsa-miR-513a-5p hsa-miR-134 hsa-miR-301a hsa-miR-342-3p hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC7 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZDHC7_HUMAN, Q9NXF8: Membrane; Multi-pass membrane protein (Potential). Golgi apparatus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    plasma membrane3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IDA16647879
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ZDHHC7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC7
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for ZDHHC7 (Q9NXF82, 3 ENSP000003416814) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000225987P404252, 3, ENSP000004039484MINT-62528 I2D: score=4 STRING: ENSP00000403948
    ENSG00000237344P404252, 3, ENSP000003971774MINT-62528 I2D: score=4 STRING: ENSP00000397177
    PBX2P404252, 3, ENSP000003641904MINT-62528 I2D: score=4 STRING: ENSP00000364190
    ENSG00000206315P404252, 3MINT-62528 I2D: score=4 
    ENSG00000224952P404252, 3MINT-62528 I2D: score=4 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018230peptidyl-L-cysteine S-palmitoylation IMP--
    GO:0018345protein palmitoylation IDA--

    Find genes that share ontologies with ZDHHC7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC7 (ZDHC7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZDHHC7 gene (2 alternative transcripts): 
    NM_001145548.1  NM_017740.2  

    Unigene Cluster for ZDHHC7:

    Zinc finger, DHHC-type containing 7
    Hs.461610  [show with all ESTs]
    Unigene Representative Sequence: NM_001145548
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000313732(uc010voi.1 uc002fiq.2) ENST00000344861(uc002fir.1)
    ENST00000564526 ENST00000564466 ENST00000569377 ENST00000566909 ENST00000569488
    ENST00000569017
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC7 (see all 55):
    hsa-miR-3164 hsa-miR-376b hsa-miR-146a hsa-miR-513a-5p hsa-miR-134 hsa-miR-301a hsa-miR-342-3p hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC7 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC7
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC7

    Additional mRNA sequence: 

    AK000286.1 AK001654.1 AK023428.1 AK130081.1 AK225768.1 BC017702.1 BC018772.1 FJ423745.1 

    9 DOTS entries:

    DT.412387  DT.121644348  DT.75100084  DT.97785662  DT.100818232  DT.120655902  DT.40209491  DT.91655446 
    DT.92062187 

    Selected AceView cDNA sequences (see all 147):

    CR603994 BP340600 BI324915 BQ690152 CA444808 BU838105 AI363349 BU727672 
    AA441896 BM996368 AI656387 BI467232 AW005144 BU623845 BG169502 AW005154 
    BX280922 BU627452 AU132797 AK130081 CB854776 AK023428 AW850701 AW005145 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC7 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d
    SP1:              -                                   -                 -           -                                       
    SP2:              -                             -     -                 -           -                                       
    SP3:                                                                    -           -                                       
    SP4:                                            -     -     -           -           -                                       
    SP5:                                                                                -                                       


    ECgene alternative splicing isoforms for ZDHHC7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZDHHC7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGTGTGGGCT
    ZDHHC7 Expression
    About this image


    ZDHHC7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Limb (Muscoskeletal System)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Stomach (Gastrointestinal Tract)
    ZDHHC7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.461610
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZDHHC7 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc71 , 5 zinc finger, DHHC domain containing 71, 5 85.93(n)1
    95.13(a)1
      8 (68.93 cM)5
    1021931  NM_133967.31  NP_598728.11 
     1200810955 
    chicken
    (Gallus gallus)
    Aves ZDHHC71 zinc finger, DHHC-type containing 7 81.75(n)
    90.16(a)
      415821  XM_414183.4  XP_414183.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC76
    zinc finger, DHHC-type containing 7
    91(a)
    1 ↔ 1
    GL343617.1(228172-242456)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004858871 palmitoyltransferase ZDHHC7-like 77.19(n)
    85.53(a)
      100485887  XM_004913635.1  XP_004913692.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zdhhc71 zinc finger, DHHC-type containing 7 74.5(n)
    80.2(a)
      436875  NM_001002602.1  NP_001002602.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG83143   -- 56(a)   52D9   --
    worm
    (Caenorhabditis elegans)
    Secernentea F33D11.123   -- 55(a)
    (best of 2)
      I(5871167-5872804)   --


    ENSEMBL Gene Tree for ZDHHC7 (if available)
    TreeFam Gene Tree for ZDHHC7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZDHHC7 gene
    ZDHHC212  ZDHHC32  ZDHHC202  ZDHHC162  ZDHHC62  ZDHHC22  ZDHHC152  
    5 SIMAP similar genes for ZDHHC7 using alignment to 3 protein entries:     ZDHC7_HUMAN (see all proteins):
    ZDHHC3    ZDHHC2    ZDHHC1    ZDHHC18    ZDHHC5

    Find genes that share paralogs with ZDHHC7           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for ZDHHC7
    PGOHUM00000262391 PGOHUM00000234745 PGOHUM00000249293


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZDHHC7 (see all 1180)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362614
    A colorectal cancer sample4--see VAR_0362612 D N mis40--------
    rs80519261,2
    C,F,A--85007610(+) GGCTGC/TGGCAC 2 -- int15Minor allele frequency- T:0.09NA WA EA 362
    rs1906068001,2
    --85007660(+) GCTGCA/GGCACA 2 -- int10--------
    rs1411658711,2
    --85007674(+) TGACCA/CTCTGG 2 -- int10--------
    rs1456369261,2
    C--85007798(+) AAACA-/TTGT  
            
    TTGTT
    2 -- int10--------
    rs1828962261,2
    --85007843(+) AAAACG/TATGGG 2 -- int10--------
    rs1879181971,2
    --85007903(+) TGAGTC/TGCGCT 2 -- int10--------
    rs99337851,2
    C,F,H--85007961(+) TGGAAA/GCTGTT 2 -- int118Minor allele frequency- G:0.13NS EA NA WA CSA 2022
    rs772961541,2
    F--85007985(+) AACAGC/TCTGGG 2 -- int11Minor allele frequency- T:0.05WA 118
    rs1462090801,2
    --85007990(+) CCTGGA/GGCTGG 2 -- int10--------

    HapMap Linkage Disequilibrium report for ZDHHC7 (85007787 - 85045141 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZDHHC7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660467CNV Deletion23128226
    nsv907087CNV Loss21882294
    esv29431CNV Loss19812545
    nsv907088CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614604    OMIM disorders: --


    Find genes that share disorders with ZDHHC7           About GenesLikeMe

    Genetic Association Database (GAD): ZDHHC7

    Export disorders for ZDHHC7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZDHHC7 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ZDHHC7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors. (PubMed id 22031296)1, 2 Pedram A.... Levin E.R. (Mol. Biol. Cell 2012)
    2. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. (PubMed id 16647879)1 Ohno Y....Igarashi Y. (Biochim. Biophys. Acta 2006)
    10. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55625 HGNC: 18459 AceView: ZDHHC7 Ensembl:ENSG00000153786 euGenes: HUgn55625
    ECgene: ZDHHC7 H-InvDB: ZDHHC7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZDHHC7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZDHHC7 gene:
    Search GeneIP for patents involving ZDHHC7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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