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ZDHHC6 Gene

protein-coding   GIFtS: 51
GCID: GC10M114180

Zinc Finger, DHHC-Type Containing 6

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, DHHC-Type Containing 61 2     Palmitoyltransferase ZDHHC62
Transmembrane Protein H42 3     Probable Palmitoyltransferase ZDHHC62
Zinc Finger DHHC Domain-Containing Protein 62 3     Zinc Finger, DHHC Domain Containing 62
Zinc Finger Protein 3762 3     EC 2.3.1.2253
DHHC-62 3     EC 2.3.18
ZNF3762 3     

External Ids:    HGNC: 191601   Entrez Gene: 644292   Ensembl: ENSG000000230417   UniProtKB: Q9H6R63   

Export aliases for ZDHHC6 gene to outside databases

Previous GC identifers: GC10M113083 GC10M113423 GC10M114321 GC10M113854 GC10M107817


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZDHHC6 Gene:
ZDHHC6 (zinc finger, DHHC-type containing 6) is a protein-coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC21.

UniProtKB/Swiss-Prot: ZDHC6_HUMAN, Q9H6R6
Function: Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon
complex and efficient folding of glycosylated proteins




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC6 gene promoter:
         AML1a   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC6 promoter sequence
   Search Chromatin IP Primers for ZDHHC6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.2   Ensembl cytogenetic band:  10q25.2   HGNC cytogenetic band: 10q26.11

ZDHHC6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC6 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M114180:  view genomic region     (about GC identifiers)

Start:
114,190,058 bp from pter      End:
114,206,672 bp from pter
Size:
16,615 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZDHC6_HUMAN, Q9H6R6 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC6  
Size: 413 amino acids; 47663 Da
Sequence caution: Sequence=BAB15462.1; Type=Erroneous initiation;
Secondary accessions: D3DRB6 Q53G45 Q96IV7 Q9H605
Alternative splicing: 2 isoforms:  Q9H6R6-1   Q9H6R6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZDHHC6: NX_Q9H6R6

Explore proteomics data for ZDHHC6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ZDHHC6 (Q9H6R6) (see all 5)
     MDHHCPW  FPYDMGS  QNHASFTLFLLLAPLGC  QYSLTIEQLKQKADKRVRSVRYKVIEDY 


    See ZDHHC6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071939.1  
    ENSEMBL proteins: 
     ENSP00000358413   ENSP00000358412  

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    Cloud-Clone Corp. Proteins for ZDHHC6

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    3 InterPro protein domains:
     IPR001594 Znf_DHHC_palmitoyltrfase
     IPR001452 SH3_domain
     IPR011511 SH3_2

    Graphical View of Domain Structure for InterPro Entry Q9H6R6

    ProtoNet protein and cluster: Q9H6R6

    2 Blocks protein domains:
    IPB001594 Zn-finger
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: ZDHC6_HUMAN, Q9H6R6
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDHC6_HUMAN, Q9H6R6
    Function: Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon
    complex and efficient folding of glycosylated proteins
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    Find genes that share ontologies with ZDHHC6           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZDHHC6:
     Increased G2M DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC6
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    miRTarBase miRNAs that target ZDHHC6:
    hsa-mir-186-5p (MIRT045294), hsa-mir-19b-1-5p (MIRT038979)

    Block miRNA regulation of human, mouse, rat ZDHHC6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC6 (see all 9):
    hsa-miR-3910 hsa-miR-498 hsa-miR-183 hsa-miR-1297 hsa-miR-135b hsa-miR-26a hsa-miR-3915 hsa-miR-26b
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC6

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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZDHC6_HUMAN, Q9H6R6: Endoplasmic reticulum membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    plasma membrane3
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA16647879
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ZDHHC6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC6
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for ZDHHC6 (Q9H6R62, 3 ENSP000003584134) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GOT2P005052, 3, ENSP000002452064MINT-63342 I2D: score=4 STRING: ENSP00000245206
    CITED4Q96RK13I2D: score=1 
    EWSR1Q018443I2D: score=1 
    GMEB1Q9Y6923I2D: score=1 
    HOXA2O433643I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018345protein palmitoylation IDA--

    Find genes that share ontologies with ZDHHC6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC6 (ZDHC6)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZDHHC6 gene: 
    NM_022494.1  

    Unigene Cluster for ZDHHC6:

    Zinc finger, DHHC-type containing 6
    Hs.196990  [show with all ESTs]
    Unigene Representative Sequence: BX647270
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369405(uc001kzv.3 uc001kzw.3 uc009xya.1) ENST00000369404
    ENST00000482410 ENST00000471035
    miRNA
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    Block miRNA regulation of human, mouse, rat ZDHHC6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC6 (see all 9):
    hsa-miR-3910 hsa-miR-498 hsa-miR-183 hsa-miR-1297 hsa-miR-135b hsa-miR-26a hsa-miR-3915 hsa-miR-26b
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC6
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    GenScript: all cDNA clones in your preferred vector: ZDHHC6 (NM_022494)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC6
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC6
      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC6
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC6

    Additional mRNA sequence: 

    AF267740.1 AK025605.1 AK026369.1 AK054991.1 AK223086.1 AK308026.1 BC007213.1 BC017434.2 
    BX647270.1 

    15 DOTS entries:

    DT.316091  DT.121217269  DT.99941334  DT.121217350  DT.316095  DT.97844614  DT.121217088  DT.99929190 
    DT.121217250  DT.102842209  DT.95253090  DT.97766987  DT.100780921  DT.121217120  DT.121217358 

    Selected AceView cDNA sequences (see all 193):

    CA397275 CD677507 CD722121 AI921374 BC007213 AI027610 BC017434 AI625669 
    AI003234 F03815 Z38935 AI424445 F07576 AA897114 BE041418 AA806202 
    BF115013 AA788798 H52302 BF513470 NM_022494 AW591218 AA127273 AA287717 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC6 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c
    SP1:                          -                                               -                 -           -     -     -                                       
    SP2:                          -                       -                       -                 -           -     -     -                                       
    SP3:                                                                                                                                                            
    SP4:                                                                          -     -           -                                                               
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for ZDHHC6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZDHHC6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGTACTTCT
    ZDHHC6 Expression
    About this image

    ZDHHC6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.196990
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZDHHC6 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc61 , 5 zinc finger, DHHC domain containing 61, 5 89.02(n)1
    92.74(a)1
      19 (51.33 cM)5
    669801  NM_001033573.11  NP_001028745.11 
     552983015 
    chicken
    (Gallus gallus)
    Aves ZDHHC61 zinc finger, DHHC-type containing 6 78.71(n)
    82.69(a)
      423897  XM_421759.4  XP_421759.4 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC66
    zinc finger, DHHC-type containing 6
    78(a)
    1 ↔ 1
    GL343204.1(1940633-1961983)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC526472 similar to zinc finger, DHHC domain containing 6 73.4(n)    BC041720.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa04d122 wufa04d12 74.32(n)   334821  57048494 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG51961 CG5196 49.17(n)
    42.54(a)
      41522  NM_141934.1  NP_650191.1 
    worm
    (Caenorhabditis elegans)
    Secernentea M18.81 M18.8 50.84(n)
    39.84(a)
      178158  NM_069901.6  NP_502302.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFA4(YOL003C)4 Palmitoyltransferase with autoacylation activity, required more   --   15(322994-321858) 854159  NP_014640.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G093201 AT3G09320 48.73(n)
    37.14(a)
      820088  NM_111766.2  NP_566348.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g04580001 Os05g0458000 46.17(n)
    37.43(a)
      4338999  NM_001062277.1  NP_001055742.1 


    ENSEMBL Gene Tree for ZDHHC6 (if available)
    TreeFam Gene Tree for ZDHHC6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZDHHC6 gene
    ZDHHC212  ZDHHC32  ZDHHC72  ZDHHC202  ZDHHC162  ZDHHC22  ZDHHC152  

    Find genes that share paralogs with ZDHHC6           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ZDHHC6
    PGOHUM00000240686


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZDHHC6 (see all 285)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs733630631,2
    --114189661(+) GCACCA/CGGGCT 1 -- int10--------
    rs1416734491,2
    C--114189725(+) TTGTT-/GGGGGG 1 -- int10--------
    rs1862150971,2
    --114189726(+) TGTTGA/GGGGGG 1 -- int10--------
    rs1924282931,2
    --114189772(+) AGCACA/TAGGAT 1 -- int10--------
    rs1824711721,2
    --114189775(+) ACAAGC/GATGCC 1 -- int10--------
    rs1452038941,2
    --114189875(+) CATCCA/GCTGCC 1 -- int10--------
    rs1491303211,2
    --114189956(+) GTTTTA/GAGATG 1 -- int10--------
    rs779106951,2
    C,F--114190020(+) CTTTTT/CAGTCA 1 -- int11Minor allele frequency- C:0.05WA 118
    rs22909631,2
    C,H--114190291(+) AAAATC/TCTACA 1 -- ut314Minor allele frequency- T:0.00NS EA 418
    rs22909641,2
    C,H--114190292(+) AAATCC/TTACAG 1 -- ut31 ese34Minor allele frequency- T:0.00NS EA 420

    HapMap Linkage Disequilibrium report for ZDHHC6 (114190058 - 114206672 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ZDHHC6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2741040CNV Deletion23290073
    esv2741029CNV Deletion23290073
    nsv831990CNV Loss17160897
    nsv831991CNV Loss17160897
    nsv7211OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZDHHC6           About GenesLikeMe

    Genetic Association Database (GAD): ZDHHC6
    Human Genome Epidemiology (HuGE) Navigator: ZDHHC6 (1 document)

    Export disorders for ZDHHC6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZDHHC6 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ZDHHC6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Genome-wide meta-analysis identifies new susceptibility loci for migraine. (PubMed id 23793025)1 Anttila V.... . (Nat. Genet. 2013)
    5. Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PubMed id 22745667)1 Asbach B....Wagner R. (PLoS ONE 2012)
    6. Palmitoylated calnexin is a key component of the ribosome-translocon complex. (PubMed id 22314232)2 Lakkaraju A.K.... van der Goot F.G. (EMBO J. 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. (PubMed id 19801377)1 Yang W....Freeman M.R. (amp 2010)
    10. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. (PubMed id 16647879)1 Ohno Y....Igarashi Y. (Biochim. Biophys. Acta 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64429 HGNC: 19160 AceView: ZDHHC6 Ensembl:ENSG00000023041 euGenes: HUgn64429
    ECgene: ZDHHC6 H-InvDB: ZDHHC6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZDHHC6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZDHHC6 gene:
    Search GeneIP for patents involving ZDHHC6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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