Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZDHHC5 Gene

protein-coding   GIFtS: 51
GCID: GC11P057435

Zinc Finger, DHHC-Type Containing 5

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger, DHHC-Type Containing 51 2     Membrane-Associated DHHC5 Zinc Finger Protein2
ZNF3752 3 5     Palmitoyltransferase ZDHHC52
Zinc Finger DHHC Domain-Containing Protein 52 3     Probable Palmitoyltransferase ZDHHC52
Zinc Finger Protein 3752 3     Zinc Finger, DHHC Domain Containing 52
DHHC-52 3     EC 2.3.1.2253
DHHC52 5     EC 2.3.18
KIAA17483 5     

External Ids:    HGNC: 184721   Entrez Gene: 259212   Ensembl: ENSG000001565997   OMIM: 6145865   UniProtKB: Q9C0B53   

Export aliases for ZDHHC5 gene to outside databases

Previous GC identifers: GC11P059829 GC11P058948 GC11P057686 GC11P057210 GC11P057192 GC11P053784


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZDHHC5 Gene:
ZDHHC5 (zinc finger, DHHC-type containing 5) is a protein-coding gene. GO annotations related to this gene include palmitoyltransferase activity. An important paralog of this gene is ZDHHC1.

UniProtKB/Swiss-Prot: ZDHC5_HUMAN, Q9C0B5
Function: Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2 (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC5 gene promoter:
         C/EBPbeta   AP-1   MIF-1   AREB6   CREB   IRF-2   deltaCREB   FOXJ2 (long isoform)   IRF-7A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC5 promoter sequence
   Search Chromatin IP Primers for ZDHHC5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.1   Ensembl cytogenetic band:  11q12.1   HGNC cytogenetic band: 11q13.1

ZDHHC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC5 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P057435:  view genomic region     (about GC identifiers)

Start:
57,435,219 bp from pter      End:
57,468,659 bp from pter
Size:
33,441 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZDHC5_HUMAN, Q9C0B5 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC5  
Size: 715 amino acids; 77545 Da
Sequence caution: Sequence=BAB21839.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAD18778.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q2TGF0 Q6ZMF0 Q8TAK8 Q9H923 Q9UFI7
Alternative splicing: 2 isoforms:  Q9C0B5-1   Q9C0B5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZDHHC5: NX_Q9C0B5

Explore proteomics data for ZDHHC5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys224
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ZDHHC5 (Q9C0B5) (see all 20)
     WVNNCIG  PPFLRPE  FGLLYVL  SYSSQKA 


    See ZDHHC5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056272.2  
    ENSEMBL proteins: 
     ENSP00000432202   ENSP00000287169   ENSP00000431209   ENSP00000435593   ENSP00000435722  

    ZDHHC5 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZDHHC5
    GenScript Custom Purified and Recombinant Proteins Services for ZDHHC5
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZDHHC5

     
    Search eBioscience for Proteins for ZDHHC5 

    ZDHHC5 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZDHHC5
    Novus Biologicals ZDHHC5 Antibody
    Abcam antibodies for ZDHHC5
    Cloud-Clone Corp. Antibodies for ZDHHC5
    Search ThermoFisher Antibodies for ZDHHC5
    LSBio Antibodies in human, mouse, rat for ZDHHC5

    ZDHHC5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZDHHC5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZDHHC5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZDHHC5
    Cloud-Clone Corp. CLIAs for ZDHHC5
    Search eBioscience for ELISAs for ZDHHC5 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q9C0B5

    ProtoNet protein and cluster: Q9C0B5

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDHC5_HUMAN, Q9C0B5
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDHC5_HUMAN, Q9C0B5
    Function: Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5. Also palmitoylates FLOT2 (By
    similarity)
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0016746transferase activity, transferring acyl groups ----
         
    Find genes that share ontologies with ZDHHC5           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for ZDHHC5:
     Cell division defect  Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZDHHC5

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZDHHC5:
    hsa-mir-32-5p (MIRT028354), hsa-mir-125b-5p (MIRT046025), hsa-mir-331-3p (MIRT043482)

    Block miRNA regulation of human, mouse, rat ZDHHC5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC5 (see all 54):
    hsa-miR-642a hsa-miR-218-1* hsa-miR-29a hsa-miR-25 hsa-miR-374a hsa-miR-29b-1* hsa-miR-3167 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZDHHC5
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZDHHC5

    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC5 (see all 7)
    OriGene ORF clones in mouse, rat for ZDHHC5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZDHHC5 (NM_015457)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC5

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZDHHC5
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZDHC5_HUMAN, Q9C0B5: Cell membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA16647879
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0030425dendrite IEA--

    Find genes that share ontologies with ZDHHC5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC5
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC5

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ZDHHC5 (Q9C0B53 ENSP000002871694) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSTR5P353463, ENSP000002938974I2D: score=1 STRING: ENSP00000293897
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development ----
    GO:0018345protein palmitoylation IDA--

    Find genes that share ontologies with ZDHHC5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC5 (ZDHC5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZDHHC5 gene: 
    NM_015457.2  

    Unigene Cluster for ZDHHC5:

    Zinc finger, DHHC-type containing 5
    Hs.27239  [show with all ESTs]
    Unigene Representative Sequence: AY894889
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000527985 ENST00000287169(uc001nkx.1 uc001nky.1) ENST00000528177
    ENST00000524540 ENST00000527090 ENST00000532842 ENST00000529480(uc001nkz.1)
    ENST00000529447
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZDHHC5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC5 (see all 54):
    hsa-miR-642a hsa-miR-218-1* hsa-miR-29a hsa-miR-25 hsa-miR-374a hsa-miR-29b-1* hsa-miR-3167 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZDHHC5
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC5
    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC5 (see all 7)
    OriGene ORF clones in mouse, rat for ZDHHC5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZDHHC5 (NM_015457)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC5
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC5
      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC5
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC5

    Additional mRNA sequence: 

    AB051535.1 AK023130.1 AK172807.1 AL117662.1 AY894889.1 BC026967.1 BX647707.1 

    12 DOTS entries:

    DT.100645408  DT.455986  DT.100654374  DT.100645410  DT.91893747  DT.100645409  DT.95269994  DT.95269995 
    DT.120733924  DT.97801577  DT.86853437  DT.97795465 

    Selected AceView cDNA sequences (see all 216):

    AA455663 AI520995 BC026967 CF125801 NM_015457 AA203170 CB045993 AK172807 
    BX456375 AI524470 BQ053572 CR614518 AL046025 Z38973 BU627218 BE889836 
    BU542569 BF094317 AI354991 AK023130 AB051535 BF064007 BM662367 AL551085 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC5 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b
    SP1:                    -     -                 -                                                                                 
    SP2:                    -     -     -     -     -                                                                                 
    SP3:                                                                                                                              
    SP4:                                                              -     -                                                         
    SP5:                    -     -     -     -     -     -                                                                           


    ECgene alternative splicing isoforms for ZDHHC5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZDHHC5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAAAAACGG
    ZDHHC5 Expression
    About this image

    ZDHHC5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.27239
        Custom PCR Arrays for ZDHHC5
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC5
    QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC5
    QuantiFast Probe-based Assays in human, mouse, rat ZDHHC5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for ZDHHC5 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc51 , 5 zinc finger, DHHC domain containing 51, 5 92.54(n)1
    97.9(a)1
      2 (49.45 cM)5
    2281361  NM_144887.41  NP_659136.11 
     846879705 
    chicken
    (Gallus gallus)
    Aves ZDHHC51 zinc finger, DHHC-type containing 5 76.69(n)
    84.97(a)
      423130  NM_001039600.1  NP_001034689.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC56
    zinc finger, DHHC-type containing 5
    87(a)
    1 ↔ 1
    1(91536510-91569142)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.156082 Transcribed sequences 71.41(n)    142025671 
    zebrafish
    (Danio rerio)
    Actinopterygii zdhhc5a1 zinc finger, DHHC-type containing 5a 60.77(n)
    64.63(a)
      571795  NM_001039640.1  NP_001034729.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG344496
    --
    24(a)
    1 → many
    X(9220691-9250260)
    worm
    (Caenorhabditis elegans)
    Secernentea Y39E4B.73   -- 48(a)   III(13178976-13185359)   --


    ENSEMBL Gene Tree for ZDHHC5 (if available)
    TreeFam Gene Tree for ZDHHC5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZDHHC5 gene
    ZDHHC12  ZDHHC142  ZDHHC112  ZDHHC11B2  ZDHHC42  ZDHHC82  ZDHHC192  ZDHHC92  
    ZDHHC182  
    8 SIMAP similar genes for ZDHHC5 using alignment to 4 protein entries:     ZDHC5_HUMAN (see all proteins):
    ZDHHC14    ZDHHC8    ZDHHC2    ZDHHC18    ZDHHC1    ZDHHC11B
    ZDHHC3    ZDHHC7

    Find genes that share paralogs with ZDHHC5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZDHHC5 (see all 720)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17981741,2
    C,F--57433742(+) GCTCAC/TGGCAA 1 -- us2k15Minor allele frequency- T:0.27NA WA 126
    rs1406501871,2
    --57433771(+) AAGCAA/GTTCTC 1 -- us2k10--------
    rs1445105571,2
    C--57434007(+) TCAAGC/TGTGTT 1 -- us2k10--------
    rs4991881,2
    C,F,A,H--57434122(-) GTAAGG/TTAAAA 1 -- us2k126Minor allele frequency- T:0.28NA EA NS WA 2714
    rs1478834361,2
    --57434230(+) TCAGGC/GAAGTG 1 -- us2k10--------
    rs1845088711,2
    --57434340(+) TTGCTA/TTTGGG 1 -- us2k10--------
    rs1489338041,2
    --57434405(+) AGTTAA/GCTCGC 1 -- us2k10--------
    rs343583361,2
    C--57434837(+) CCATC-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs116016071,2
    C,H--57434906(+) GGTTGG/TCCAAT 1 -- us2k14Minor allele frequency- T:0.03EA NS NA 416
    rs1162721861,2
    F--57435008(+) GAGGGG/TTTGCT 1 -- us2k11Minor allele frequency- T:0.02WA 118

    HapMap Linkage Disequilibrium report for ZDHHC5 (57435219 - 57468659 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ZDHHC5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832164CNV Loss17160897
    nsv508633CNV Loss20534489
    nsv832163CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZDHHC5
    DNA2.0 Custom Variant and Variant Library Synthesis for ZDHHC5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 614586    OMIM disorders: --


    Find genes that share disorders with ZDHHC5           About GenesLikeMe


    Export disorders for ZDHHC5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZDHHC5 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with ZDHHC5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase. (PubMed id 21820437)1, 2 Kokkola T.... Kreienkamp H.J. (FEBS Lett. 2011)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 25921 HGNC: 18472 AceView: ZDHHC5 Ensembl:ENSG00000156599 euGenes: HUgn25921
    ECgene: ZDHHC5 H-InvDB: ZDHHC5

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1748

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZDHHC5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZDHHC5 gene:
    Search GeneIP for patents involving ZDHHC5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZDHHC5  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZDHHC5  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC5   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZDHHC5   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZDHHC5   OriGene Custom Protein Services for ZDHHC5  

     
     
     Block miRNA regulation of human, mouse, rat ZDHHC5 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZDHHC5
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC5 Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC5
     QuantiFast Probe-based Assays in human, mouse, rat ZDHHC5 QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC5
     Custom PCR Arrays for ZDHHC5 Search Chromatin IP Primers for ZDHHC5
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC5  Search GeneGlobe Interaction Network for ZDHHC5
     Regulatory tfbs in ZDHHC5 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZDHHC5 GenScript cDNA clones with any tag delivered in your preferred vector for ZDHHC5
     GenScript Custom Assay Services for ZDHHC5 GenScript Custom overexpressing Cell Line Services for ZDHHC5
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZDHHC5 (ZDHC5)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZDHHC5 antibodies
     Antibodies for ZDHHC5
     See all of Abcam's Antibodies, Kits and Proteins for ZDHHC5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZDHHC5
     Antibodies for ZDHHC5
     ELISAs for ZDHHC5
     CLIAs for ZDHHC5



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC5
     SwitchGear 3'UTR luciferase reporter plasmids for ZDHHC5
     SwitchGear Promoter luciferase reporter plasmids for ZDHHC5
     Search ThermoFisher Antibodies for ZDHHC5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC5
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC5
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC5
     LSBio Antibodies in human, mouse, rat for ZDHHC5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZDHHC5
      Search eBioscience for proteins for ZDHHC5
      Search eBioscience for elisas for ZDHHC5
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZDHHC5 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4