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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZDHHC3 Gene

protein-coding   GIFtS: 51
GCID: GC03M044941

Zinc Finger, DHHC-Type Containing 3

  Search for ZDHHC3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger, DHHC-Type Containing 31 2     DHHC1 Protein2
Golgi-Specific DHHC Zinc Finger Protein1 2     Golgi Apparatus-Specific Protein With DHHC Zinc Finger Domain2
Zinc Finger DHHC Domain-Containing Protein 32 3     Palmitoyltransferase ZDHHC32
Zinc Finger Protein 3732 3     Zinc Finger, DHHC Domain Containing 32
DHHC-32 3     EC 2.3.1.-3
ZNF3732 3     Protein DHHC13
GODZ2     EC 2.3.18

External Ids:    HGNC: 184701   Entrez Gene: 513042   Ensembl: ENSG000001638127   UniProtKB: Q9NYG23   

Export aliases for ZDHHC3 gene to outside databases

Previous GC identifers: GC03M043924 GC03M044146 GC03M044785 GC03M044927


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZDHHC3 Gene: 
ZDHHC3 (zinc finger, DHHC-type containing 3) is a protein-coding gene. GO annotations related to this gene include palmitoyltransferase activity and zinc ion binding. An important paralog of this gene is ZDHHC21.

UniProtKB/Swiss-Prot: ZDHC3_HUMAN, Q9NYG2
Function: Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit
(GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates
glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity)

Gene Wiki entry for ZDHHC3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZDHHC3 gene promoter:
         AML1a   NF-E2 p45   E47   GATA-1   AREB6   PPAR-gamma1   POU2F1   POU2F1a   PPAR-gamma2   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZDHHC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZDHHC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

ZDHHC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M044941:  view genomic region     (about GC identifiers)

Start:
44,956,749 bp from pter      End:
45,017,677 bp from pter
Size:
60,929 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZDHC3_HUMAN, Q9NYG2 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC3  
Size: 299 amino acids; 34170 Da
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: Q53A17 Q96BL0
Alternative splicing: 2 isoforms:  Q9NYG2-1   Q9NYG2-2   

Explore the universe of human proteins at neXtProt for ZDHHC3: NX_Q9NYG2

Explore proteomics data for ZDHHC3 at MOPED 

Post-translational modifications:

  • UniProtKB: Autopalmitoylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NYG2

  • 4/5 DME Specific Peptides for ZDHHC3 (Q9NYG2) (see all 5)
     MDHHCPW  KPDRAHH  WFIRDGCG  FVLFTMYIAL 

    ZDHHC3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZDHHC3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001128651.1  NP_057682.1  

    ENSEMBL proteins: 
     ENSP00000404108   ENSP00000402545   ENSP00000296127   ENSP00000395502   ENSP00000345268  
     ENSP00000416132   ENSP00000408294   ENSP00000409755  

    Human Recombinant Protein Products for ZDHHC3: 
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    Cloud-Clone Corp. Proteins for ZDHHC3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005794Golgi apparatus ----
    GO:0016021integral to membrane IEA--

    ZDHHC3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q9NYG2

    ProtoNet protein and cluster: Q9NYG2

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDHC3_HUMAN, Q9NYG2
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    ZDHHC3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDHC3_HUMAN, Q9NYG2
    Function: Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit
    (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates
    glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity)
    Catalytic activity: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA

         Enzyme Numbers (IUBMB): EC 2.3.12 EC 2.3.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IEA--
         
    ZDHHC3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ZDHHC3:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 

         1 MGI phenotypic allele for Zdhhc3 (no phenotypes)

    ZDHHC3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZDHHC3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZDHHC3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC3 
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    hsa-miR-3678-3p hsa-miR-520f hsa-miR-411 hsa-miR-219-5p hsa-miR-1304 hsa-miR-298 hsa-miR-3622b-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZDHHC3

    5/8 Interacting proteins for ZDHHC3 (Q9NYG22, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD1Q157972, 3MINT-62020 I2D: score=2 
    UBQLN4Q9NRR52, 3MINT-2873175 I2D: score=2 
    EWSR1Q018443I2D: score=3 
    MAP2K2P365073I2D: score=2 
    DLG4P783523I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006605protein targeting IEA--
    GO:0018345protein palmitoylation IEA--

    ZDHHC3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZDHHC3 (ZDHC3)

    Search CenterWatch for drugs/clinical trials and news about ZDHHC3 / ZDHC3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZDHHC3 gene (3 alternative transcripts): 
    NM_001135180.1  NM_001135179.1  NM_016598.2  

    Unigene Cluster for ZDHHC3:

    Zinc finger, DHHC-type containing 3
    Hs.61430  [show with all ESTs]
    Unigene Representative Sequence: NM_016598
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000339420(uc003cod.3 uc003cog.3 uc021wws.1) ENST00000466084(uc003coe.3)
    ENST00000443879 ENST00000296127 ENST00000424952 ENST00000479314 ENST00000342790
    ENST00000433512 ENST00000455235 ENST00000419642 ENST00000478669
    miRNA
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    hsa-miR-3678-3p hsa-miR-520f hsa-miR-411 hsa-miR-219-5p hsa-miR-1304 hsa-miR-298 hsa-miR-3622b-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC3 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF052182.1 AF247703.1 AF441791.1 AK000216.1 AK127837.1 AK299782.1 AL832057.1 AY605661.1 
    BC015467.1 BC020350.1 BC020424.1 BC038436.1 BC101284.2 BC101285.2 BC101286.1 BC101287.1 
    BC113070.1 

    20 DOTS entries:

    DT.213263  DT.86852866  DT.95355250  DT.100784266  DT.91803935  DT.409323  DT.102835693  DT.95338420 
    DT.97789758  DT.97804608  DT.120916346  DT.95107340  DT.95176844  DT.95259807  DT.100001040  DT.100740134 
    DT.95100237  DT.97839323  DT.100784268  DT.120916353 

    24/357 AceView cDNA sequences (see all 357):

    AW196576 BU687759 BM793017 BM728284 CA421254 AL597825 BQ051560 NM_016598 
    AI339876 CD370639 AI378354 CA446868 AA352136 AA778122 AI569742 AA716358 
    BC015467 AI583708 BQ021617 BC020424 BF062974 AI308759 BM931144 BM983310 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC3 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:                                            -                 -                                                   
    SP2:                                                              -                 -                                 
    SP3:                                            -                 -                 -                                 
    SP4:                                                              -                                                   
    SP5:                                            -                 -                                                   


    ECgene alternative splicing isoforms for ZDHHC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZDHHC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAACAAAAT
    ZDHHC3 Expression
    About this image


    See ZDHHC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZDHHC3

    SOURCE GeneReport for Unigene cluster: Hs.61430
        SABiosciences Custom PCR Arrays for ZDHHC3
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ZDHHC3 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc31 , 5 zinc finger, DHHC domain containing 31, 5 94.43(n)1
    97.32(a)1
      9 (73.66 cM)5
    690351  NM_026917.51  NP_081193.21 
     1230661605 
    chicken
    (Gallus gallus)
    Aves ZDHHC31 zinc finger, DHHC-type containing 3 75.51(n)
    82.31(a)
      420705  XM_418804.2  XP_418804.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC36
    Uncharacterized protein
    81(a)
    1 ↔ 1
    GL343224.1(33415-54939)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.123032 Xenopus laevis transcribed sequence with weak similarity more 77.82(n)    BJ067314.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1540291 zgc:154029 75.03(n)
    82.37(a)
      777709  NM_001077757.1  NP_001071225.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG83141 , 3 CG83141 57(a)3
    63.2(n)1
    64(a)1
      52D93
    367571  NM_137226.31  NP_611070.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F33D11.121 , 3 Protein F33D11.121 50(a)
    (best of 2)3
    57.4(n)1
    58.09(a)1
      I(5871167-5872804)3
    1722571  NM_059301.31  NP_491702.11 


    ENSEMBL Gene Tree for ZDHHC3 (if available)
    TreeFam Gene Tree for ZDHHC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZDHHC3 gene
    ZDHHC212  ZDHHC122  ZDHHC72  ZDHHC202  ZDHHC22  ZDHHC152  
    6 SIMAP similar genes for ZDHHC3 using alignment to 7 protein entries:     ZDHC3_HUMAN (see all proteins):
    ZDHHC2    ZDHHC7    ZDHHC23    ZDHHC1    ZDHHC18    ZDHHC5

    ZDHHC3 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ZDHHC3
    PGOHUM00000262392 PGOHUM00000235704


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/998 SNPs in ZDHHC3 are shown (see all 998)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs9378321,2
    H--44956690(+) CATAAG/TGAAGG 2 -- ds50015Minor allele frequency- T:0.00MN NS EA 604
    rs1408590851,2
    --44956706(+) GCCCAA/TGGGTT 2 -- ds50010--------
    rs66221,2
    C,F,A,H--44956860(+) TCAGTT/CTGAGG 2 -- ut3141Minor allele frequency- C:0.29MN EA NA NS WA CSA 3700
    rs753290031,2
    F--44956944(+) CAGGGT/CTGGAC 2 -- ut311Minor allele frequency- C:0.01WA 118
    rs1859124111,2
    --44957097(+) TCACCC/GCAGCC 2 -- ut310--------
    rs1152875281,2
    C,F--44957339(+) TGCTGC/TCCCCT 2 -- ut311Minor allele frequency- T:0.03WA 118
    rs1168506021,2
    C,F--44957452(+) AAATAG/AGGGGC 2 -- ut311Minor allele frequency- A:0.03EA 120
    rs1911612611,2
    --44957494(+) GTGAGC/TGTCAA 2 -- ut310--------
    rs1461536601,2
    --44957556(+) ATGTCA/GTCATT 2 -- ut310--------
    rs756645491,2
    C--44957627(+) CCAATA/C/GTCTTT 4 -- ut312CSA NA 121

    HapMap Linkage Disequilibrium report for ZDHHC3 (44956749 - 45017677 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZDHHC3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834675CNV Gain17160897
    nsv834676CNV Gain+Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZDHHC3 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with ZDHHC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport. (PubMed id 19955568)1, 3 Hines R.M....Quamme G.A. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. (PubMed id 23687301)1 Oku S....Fukata M. (2013)
    4. Regulation in the targeting of TRAIL receptor 1 to cel l surface via GODZ for TRAIL sensitivity in tumor cells. (PubMed id 22240897)1 Oh Y....Jung Y.K. (2012)
    5. Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin a6b4. (PubMed id 22314500)1 Sharma C....Hemler M.E. (2012)
    6. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (2009)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51304 HGNC: 18470 AceView: ZDHHC3andFLJ20209 Ensembl:ENSG00000163812 euGenes: HUgn51304
    ECgene: ZDHHC3 H-InvDB: ZDHHC3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZDHHC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZDHHC3 gene:
    Search GeneIP for patents involving ZDHHC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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