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Aliases for ZDHHC24 Gene

Aliases for ZDHHC24 Gene

  • Zinc Finger DHHC-Type Containing 24 2 3
  • Zinc Finger DHHC Domain-Containing Protein 24 3 4
  • Zinc Finger, DHHC-Type Containing 24 3 5
  • DHHC-24 3 4
  • Zinc Finger, DHHC Domain Containing 24 3
  • EC 4

External Ids for ZDHHC24 Gene

Previous GeneCards Identifiers for ZDHHC24 Gene

  • GC11M066064
  • GC11M066306
  • GC11M062638
  • GC11M066288

Summaries for ZDHHC24 Gene

GeneCards Summary for ZDHHC24 Gene

ZDHHC24 (Zinc Finger DHHC-Type Containing 24) is a Protein Coding gene. GO annotations related to this gene include protein-cysteine S-palmitoyltransferase activity. An important paralog of this gene is ZDHHC15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZDHHC24 Gene

Genomics for ZDHHC24 Gene

Regulatory Elements for ZDHHC24 Gene

Enhancers for ZDHHC24 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZDHHC24 on UCSC Golden Path with GeneCards custom track

Promoters for ZDHHC24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZDHHC24 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZDHHC24 Gene

66,520,637 bp from pter
66,546,238 bp from pter
25,602 bases
Minus strand

Genomic View for ZDHHC24 Gene

Genes around ZDHHC24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZDHHC24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZDHHC24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZDHHC24 Gene

Proteins for ZDHHC24 Gene

  • Protein details for ZDHHC24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable palmitoyltransferase ZDHHC24
    Protein Accession:
    Secondary Accessions:
    • Q6PEW7
    • Q9BSJ0

    Protein attributes for ZDHHC24 Gene

    284 amino acids
    Molecular mass:
    30176 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZDHHC24 Gene

Proteomics data for ZDHHC24 Gene at MOPED

Post-translational modifications for ZDHHC24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZDHHC24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZDHHC24 Gene

Domains & Families for ZDHHC24 Gene

Gene Families for ZDHHC24 Gene

Protein Domains for ZDHHC24 Gene

Suggested Antigen Peptide Sequences for ZDHHC24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • The DHHC domain is required for palmitoyltransferase activity.
  • Belongs to the DHHC palmitoyltransferase family.
  • Contains 1 DHHC-type zinc finger.
  • The DHHC domain is required for palmitoyltransferase activity.
  • Belongs to the DHHC palmitoyltransferase family.
  • Contains 1 DHHC-type zinc finger.
genes like me logo Genes that share domains with ZDHHC24: view

Function for ZDHHC24 Gene

Molecular function for ZDHHC24 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Enzyme Numbers (IUBMB) for ZDHHC24 Gene

Gene Ontology (GO) - Molecular Function for ZDHHC24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZDHHC24: view

Phenotypes for ZDHHC24 Gene

MGI mutant phenotypes for ZDHHC24:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with ZDHHC24: view

Animal Model Products

  • Taconic Biosciences Mouse Models for ZDHHC24

CRISPR Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZDHHC24 Gene

Localization for ZDHHC24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZDHHC24 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for ZDHHC24 Gene COMPARTMENTS Subcellular localization image for ZDHHC24 gene
Compartment Confidence
plasma membrane 3
cytosol 2
endoplasmic reticulum 1

No data available for Gene Ontology (GO) - Cellular Components for ZDHHC24 Gene

Pathways & Interactions for ZDHHC24 Gene

SuperPathways for ZDHHC24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZDHHC24 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZDHHC24 Gene

Drugs & Compounds for ZDHHC24 Gene

(1) Drugs for ZDHHC24 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Coenzyme A Nutra 0

(1) Additional Compounds for ZDHHC24 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with ZDHHC24: view

Transcripts for ZDHHC24 Gene

Unigene Clusters for ZDHHC24 Gene

Zinc finger, DHHC-type containing 24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC24 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b
SP1: -
SP2: -

Relevant External Links for ZDHHC24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZDHHC24 Gene

mRNA expression in normal human tissues for ZDHHC24 Gene

Protein differential expression in normal tissues from HIPED for ZDHHC24 Gene

This gene is overexpressed in Placenta (39.6) and CD8 Tcells (29.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZDHHC24 Gene

SOURCE GeneReport for Unigene cluster for ZDHHC24 Gene Hs.659933

genes like me logo Genes that share expression patterns with ZDHHC24: view

Protein tissue co-expression partners for ZDHHC24 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZDHHC24 Gene

Orthologs for ZDHHC24 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZDHHC24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZDHHC24 35
  • 89.79 (n)
  • 93.31 (a)
ZDHHC24 36
  • 93 (a)
(Canis familiaris)
Mammalia ZDHHC24 35
  • 91.9 (n)
  • 95.42 (a)
ZDHHC24 36
  • 95 (a)
(Mus musculus)
Mammalia Zdhhc24 35
  • 84.15 (n)
  • 87.68 (a)
Zdhhc24 16
Zdhhc24 36
  • 88 (a)
(Pan troglodytes)
Mammalia ZDHHC24 35
  • 99.37 (n)
  • 98.84 (a)
ZDHHC24 36
  • 74 (a)
(Rattus norvegicus)
Mammalia Zdhhc24 35
  • 84.39 (n)
  • 88.03 (a)
(Monodelphis domestica)
Mammalia ZDHHC24 36
  • 75 (a)
(Anolis carolinensis)
Reptilia ZDHHC24 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zdhhc24 35
  • 50.52 (n)
  • 44.92 (a)
(Danio rerio)
Actinopterygii zdhhc24 35
  • 53.26 (n)
  • 44.93 (a)
zdhhc24 36
  • 38 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009199 35
  • 49.91 (n)
  • 40.33 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10344 35
  • 46.79 (n)
  • 37.95 (a)
CG10344 36
  • 24 (a)
CG13029 36
  • 24 (a)
CG17195 36
  • 23 (a)
CG17196 36
  • 23 (a)
CG17197 36
  • 21 (a)
CG17198 36
  • 22 (a)
CG18810 36
  • 22 (a)
CG4676 36
  • 27 (a)
CG4956 36
  • 23 (a)
(Caenorhabditis elegans)
Secernentea dhhc-1 35
  • 42.03 (n)
  • 31.52 (a)
dhhc-1 36
  • 21 (a)
dhhc-10 36
  • 20 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 21 (a)
CSA.3283 36
  • 25 (a)
Species with no ortholog for ZDHHC24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZDHHC24 Gene

Gene Tree for ZDHHC24 (if available)
Gene Tree for ZDHHC24 (if available)

Paralogs for ZDHHC24 Gene

Paralogs for ZDHHC24 Gene

genes like me logo Genes that share paralogs with ZDHHC24: view

Variants for ZDHHC24 Gene

Sequence variations from dbSNP and Humsavar for ZDHHC24 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs608504 -- 66,542,454(+) ACGGG(C/T)GGTGA intron-variant, downstream-variant-500B, utr-variant-3-prime
rs610293 -- 66,542,909(+) CTTCC(C/T)GAGGC intron-variant, utr-variant-3-prime
rs640213 -- 66,538,385(+) agagc(A/C)aaact intron-variant
rs1189338 -- 66,537,640(+) ACCAT(C/G)CTGGC intron-variant
rs1201433 -- 66,537,803(+) GGCAC(A/C)TGTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZDHHC24 Gene

Variant ID Type Subtype PubMed ID
dgv1187n71 CNV Loss 21882294
nsv522277 CNV Loss 19592680
nsv897787 CNV Loss 21882294

Variation tolerance for ZDHHC24 Gene

Residual Variation Intolerance Score: 63.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.71; 86.53% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZDHHC24 Gene

Disorders for ZDHHC24 Gene

Relevant External Links for ZDHHC24

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZDHHC24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZDHHC24 Gene

Publications for ZDHHC24 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for ZDHHC24 Gene

Sources for ZDHHC24 Gene