Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZDHHC23 Gene

protein-coding   GIFtS: 48
GCID: GC03P113666

Zinc Finger, DHHC-Type Containing 23

  Search for ZDHHC23
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger, DHHC-Type Containing 231 2     Probable Palmitoyltransferase ZDHHC232
Zinc Finger DHHC Domain-Containing Protein 232 3     Zinc Finger, DHHC Domain Containing 232
DHHC-232 3     EC 2.3.1.2253
NIDD2     zDHHC233
Palmitoyltransferase ZDHHC232     

External Ids:    HGNC: 286541   Entrez Gene: 2548872   Ensembl: ENSG000001843077   UniProtKB: Q8IYP93   

Export aliases for ZDHHC23 gene to outside databases

Previous GC identifers: GC03P114988 GC03P115149 GC03P111040


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZDHHC23 Gene:
ZDHHC23 (zinc finger, DHHC-type containing 23) is a protein-coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups.

UniProtKB/Swiss-Prot: ZDH23_HUMAN, Q8IYP9
Function: Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the
plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC23 gene promoter:
         C/EBPbeta   p300   MyoD   POU3F2   YY1   Evi-1   Egr-4   Egr-2   Zic1   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC23 promoter sequence
   Search Chromatin IP Primers for ZDHHC23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.31   Ensembl cytogenetic band:  3q13.31   HGNC cytogenetic band: 3q13.31

ZDHHC23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC23 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P113666:  view genomic region     (about GC identifiers)

Start:
113,666,748 bp from pter      End:
113,684,248 bp from pter
Size:
17,501 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZDH23_HUMAN, Q8IYP9 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC23  
Size: 409 amino acids; 45983 Da
Subunit: Interacts with NOS1 (By similarity)
Secondary accessions: D3DN76

Explore the universe of human proteins at neXtProt for ZDHHC23: NX_Q8IYP9

Explore proteomics data for ZDHHC23 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZDHHC23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_775841.2  
    ENSEMBL proteins: 
     ENSP00000330485   ENSP00000417840   ENSP00000420251   ENSP00000420292   ENSP00000417579  

    ZDHHC23 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ZDHHC23
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZDHHC23
    GenScript Custom Purified and Recombinant Proteins Services for ZDHHC23
    Novus Biologicals ZDHHC23 Protein
    Novus Biologicals ZDHHC23 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZDHHC23

     
    Search eBioscience for Proteins for ZDHHC23 

    ZDHHC23 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZDHHC23
    Novus Biologicals ZDHHC23 Antibodies
    Abcam antibodies for ZDHHC23
    Cloud-Clone Corp. Antibodies for ZDHHC23
    Search ThermoFisher Antibodies for ZDHHC23
    LSBio Antibodies in human, mouse, rat for ZDHHC23

    ZDHHC23 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZDHHC23
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZDHHC23
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZDHHC23
    Cloud-Clone Corp. CLIAs for ZDHHC23
    Search eBioscience for ELISAs for ZDHHC23 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q8IYP9

    ProtoNet protein and cluster: Q8IYP9

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDH23_HUMAN, Q8IYP9
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC23           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDH23_HUMAN, Q8IYP9
    Function: Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the
    plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Number (IUBMB): EC 2.3.1.2251

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016746transferase activity, transferring acyl groups ----
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    Find genes that share ontologies with ZDHHC23           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Zdhhc23 (no phenotypes)

    Find genes that share phenotypes with ZDHHC23           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC23
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC23

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC23
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZDHHC23

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZDHHC23:
    hsa-mir-192-5p (MIRT026927), hsa-mir-215-5p (MIRT024437)

    Block miRNA regulation of human, mouse, rat ZDHHC23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC23 (see all 44):
    hsa-miR-300 hsa-miR-624* hsa-miR-301a hsa-miR-218 hsa-miR-449a hsa-miR-3142 hsa-miR-186 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC23 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZDHHC23
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZDHHC23

    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC23 (see all 6)
    OriGene ORF clones in mouse, rat for ZDHHC23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZDHHC23 (NM_173570)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC23

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZDHHC23
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC23 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZDH23_HUMAN, Q8IYP9: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ZDHHC23           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC23
    Interactions:

        GeneGlobe Interaction Network for ZDHHC23

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZDHHC23 (Q8IYP93 ENSP000003304854) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NOS1P294753, ENSP000003207584I2D: score=2 STRING: ENSP00000320758
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018345protein palmitoylation IEA--
    GO:0072659protein localization to plasma membrane IEA--

    Find genes that share ontologies with ZDHHC23           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC23 (ZDH23)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZDHHC23 gene: 
    NM_173570.3  

    Unigene Cluster for ZDHHC23:

    Zinc finger, DHHC-type containing 23
    Hs.21902  [show with all ESTs]
    Unigene Representative Sequence: AK127260
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000330212(uc003eau.3 uc003eav.3) ENST00000498275 ENST00000478793
    ENST00000491556 ENST00000488129(uc003eaw.1) ENST00000496083
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZDHHC23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC23 (see all 44):
    hsa-miR-300 hsa-miR-624* hsa-miR-301a hsa-miR-218 hsa-miR-449a hsa-miR-3142 hsa-miR-186 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC23 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZDHHC23
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC23
    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC23 (see all 6)
    OriGene ORF clones in mouse, rat for ZDHHC23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZDHHC23 (NM_173570)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC23
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZDHHC23
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC23
      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC23
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC23

    Additional mRNA sequence: 

    AF131818.1 AK022842.1 AK127025.1 AK127260.1 AK127996.1 BC035230.1 

    5 DOTS entries:

    DT.95349357  DT.100028103  DT.99992085  DT.95110597  DT.120867158 

    Selected AceView cDNA sequences (see all 69):

    AI830994 AI824803 AI207184 BF594840 AW003367 AK127996 CA389627 BM908262 
    BQ425714 AI023877 AF131818 AA813226 Z38410 AW271809 AA765840 BU607697 
    BU618853 NM_173570 AI207975 BX507161 BM786099 CD653393 AI768537 BP871742 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC23    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
    SP1:        -     -                             -           -     -                     
    SP2:                    -                       -           -     -                     
    SP3:                                            -           -           -               
    SP4:                                                                                    


    ECgene alternative splicing isoforms for ZDHHC23

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZDHHC23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAATTTTAC
    ZDHHC23 Expression
    About this image


    ZDHHC23 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Mature B-Cells Peripheral Blood
    ZDHHC23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.21902
        Custom PCR Arrays for ZDHHC23
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZDHHC23
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC23
    QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC23
    QuantiFast Probe-based Assays in human, mouse, rat ZDHHC23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ZDHHC23 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc231 , 5 zinc finger, DHHC domain containing 231, 5 87.29(n)1
    90.91(a)1
      16 (28.44 cM)5
    3321751  NM_001007460.11  NP_001007461.11 
     439691465 
    chicken
    (Gallus gallus)
    Aves ZDHHC231 zinc finger, DHHC-type containing 23 69.75(n)
    68.78(a)
      418353  NM_001012819.1  NP_001012837.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC236
    zinc finger, DHHC-type containing 23
    66(a)
    1 ↔ 1
    3(176484636-176487457)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia zdhhc231 zinc finger, DHHC-type containing 23 62.08(n)
    57.66(a)
      100379670  XM_002939646.2  XP_002939692.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zdhhc23b1 zinc finger, DHHC-type containing 23b 57.12(n)
    50.64(a)
      445301  NM_001003757.1  NP_001003757.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta GABPI1 beta4GalNAcTB pilot 43.63(n)
    30.62(a)
      33516  NM_134897.4  NP_608741.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SWF16
    Palmitoyltransferase that acts on transmembrane pr...
    17(a)
    1 ↔ 1
    IV(703234-704244) YDR126W


    ENSEMBL Gene Tree for ZDHHC23 (if available)
    TreeFam Gene Tree for ZDHHC23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZDHHC23 gene
    1 SIMAP similar gene for ZDHHC23 using alignment to 5 protein entries:     ZDH23_HUMAN (see all proteins):
    ZDHHC3

    Find genes that share paralogs with ZDHHC23           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZDHHC23 (see all 364)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1928195381,2
    --113666656(+) CAGGGC/TCGCGG 1 -- us2k10--------
    rs1168190041,2
    F--113666926(+) CGTCAC/GGCCCG 1 -- ut511Minor allele frequency- G:0.03WA 118
    rs1474312341,2
    --113667184(+) AGGGAC/GCCTGG 1 -- int10--------
    rs14872671,2
    C--113667186(+) GGAGCC/ATGGTG 1 -- int15Minor allele frequency- A:0.00EA NA MN 232
    rs1398127281,2
    C--113667221(+) TGCTTC/TGCCTT 1 -- int10--------
    rs1452909091,2
    --113667234(+) CCTATA/GGCCCC 1 -- int10--------
    rs1380851581,2
    C--113667549(+) TAAGC-/AGAGAGA 1 -- int10--------
    rs1149905521,2
    F--113667587(+) GTAAGT/CTGTGT 1 -- int11Minor allele frequency- C:0.02WA 118
    rs1844310981,2
    C--113667642(+) ACAGGC/TGCAAA 1 -- ut510--------
    rs2010144161,2
    --113667687(+) GAAAAA/GGAAAA 2 K R mis10--------

    HapMap Linkage Disequilibrium report for ZDHHC23 (113666748 - 113684248 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZDHHC23:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv25178CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZDHHC23
    DNA2.0 Custom Variant and Variant Library Synthesis for ZDHHC23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease from the University of Copenhagen DISEASES database for ZDHHC23:
    Diabetes mellitus

    Find genes that share disorders with ZDHHC23           About GenesLikeMe


    Export disorders for ZDHHC23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZDHHC23 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZDHHC23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels. (PubMed id 22399288)2 Tian L.... Shipston M.J. (J. Biol. Chem. 2012)
    4. Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. (PubMed id 22482804)1 Ellinghaus D....Franke A. (Am. J. Hum. Genet. 2012)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. NIDD, a novel DHHC-containing protein, targets neuronal nitric-oxide synthase (nNOS) to the synaptic membrane through a PDZ-dependent interaction and regulates nNOS activity. (PubMed id 15105416)1 Saitoh F....Suzuki T. (J. Biol. Chem. 2004)
    9. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (Genome Res. 1997)
    10. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 254887 HGNC: 28654 AceView: ZDHHC23 Ensembl:ENSG00000184307 euGenes: HUgn254887
    ECgene: ZDHHC23 H-InvDB: ZDHHC23

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZDHHC23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZDHHC23 gene:
    Search GeneIP for patents involving ZDHHC23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZDHHC23  
     OriGene qPCR primer pairs and template standards for ZDHHC23   OriGene Protein Over-expression Lysate for ZDHHC23  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZDHHC23  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC23   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZDHHC23   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZDHHC23   OriGene Custom Protein Services for ZDHHC23  

     
     
     Block miRNA regulation of human, mouse, rat ZDHHC23 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZDHHC23
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC23 Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC23
     QuantiFast Probe-based Assays in human, mouse, rat ZDHHC23 QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC23
     Custom PCR Arrays for ZDHHC23 Search Chromatin IP Primers for ZDHHC23
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC23  GeneGlobe Interaction Network for ZDHHC23
     Regulatory tfbs in ZDHHC23 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZDHHC23 GenScript cDNA clones with any tag delivered in your preferred vector for ZDHHC23
     GenScript Custom Assay Services for ZDHHC23 GenScript Custom overexpressing Cell Line Services for ZDHHC23
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZDHHC23 (ZDH23)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZDHHC23 antibodies
     ZDHHC23 proteins
     ZDHHC23 lysates
     Antibodies for ZDHHC23
     See all of Abcam's Antibodies, Kits and Proteins for ZDHHC23
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZDHHC23
     Antibodies for ZDHHC23
     ELISAs for ZDHHC23
     CLIAs for ZDHHC23



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC23
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC23
     SwitchGear 3'UTR luciferase reporter plasmids for ZDHHC23
     SwitchGear Promoter luciferase reporter plasmids for ZDHHC23
     Search ThermoFisher Antibodies for ZDHHC23
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC23
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC23
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC23
     LSBio Antibodies in human, mouse, rat for ZDHHC23
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZDHHC23
      Search eBioscience for proteins for ZDHHC23
      Search eBioscience for elisas for ZDHHC23
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZDHHC23 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4