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ZDHHC20 Gene

protein-coding   GIFtS: 50
GCID: GC13M021950

Zinc Finger, DHHC-Type Containing 20

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, DHHC-Type Containing 201 2     Probable Palmitoyltransferase ZDHHC202
Zinc Finger DHHC Domain-Containing Protein 202 3     EC 2.3.1.2253
DHHC-202 3     EC 2.3.18
4933421L13Rik2     

External Ids:    HGNC: 207491   Entrez Gene: 2538322   Ensembl: ENSG000001807767   UniProtKB: Q5W0Z93   

Export aliases for ZDHHC20 gene to outside databases

Previous GC identifers: GC00U907486 GC13M020845 GC13M020826 GC13M002751


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZDHHC20 Gene:
ZDHHC20 (zinc finger, DHHC-type containing 20) is a protein-coding gene. Diseases associated with ZDHHC20 include malaria. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC21.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NT_024524.15  NC_018924.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC20 gene promoter:
         STAT1   Pax-5   HOXA3   Pbx1a   GATA-3   STAT1beta   XBP-1   STAT1alpha   PPAR-alpha   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC20 promoter sequence
   Search Chromatin IP Primers for ZDHHC20

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.11   Ensembl cytogenetic band:  13q12.11   HGNC cytogenetic band: 13q12.11

ZDHHC20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC20 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M021950:  view genomic region     (about GC identifiers)

Start:
21,946,710 bp from pter      End:
22,033,509 bp from pter
Size:
86,800 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZDH20_HUMAN, Q5W0Z9 (See protein sequence)
Recommended Name: Probable palmitoyltransferase ZDHHC20  
Size: 365 amino acids; 42278 Da
Secondary accessions: A8MTV9 C9JG20 Q6NVU8
Alternative splicing: 3 isoforms:  Q5W0Z9-1   Q5W0Z9-2   Q5W0Z9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZDHHC20: NX_Q5W0Z9

Explore proteomics data for ZDHHC20 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys96, Lys123
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ZDHHC20 (Q5W0Z9) (see all 6)
     MDHHCPW  SLGCSKN  KPDRAHH  CILKMDH 


    See ZDHHC20 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001273567.1  NP_694983.2  

    ENSEMBL proteins: 
     ENSP00000383433   ENSP00000371905   ENSP00000443236   ENSP00000401232   ENSP00000313583  
     ENSP00000396819  

    ZDHHC20 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q5W0Z9

    ProtoNet protein and cluster: Q5W0Z9

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDH20_HUMAN, Q5W0Z9
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    ZDHHC20 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDH20_HUMAN, Q5W0Z9
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0016746transferase activity, transferring acyl groups ----
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    ZDHHC20 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for ZDHHC20:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC20
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC20
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZDHHC20

    miRNA
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    miRTarBase miRNAs that target ZDHHC20:
    hsa-mir-335-5p (MIRT018634)

    Block miRNA regulation of human, mouse, rat ZDHHC20 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC20 (see all 78):
    hsa-miR-411* hsa-miR-548j hsa-miR-3607-3p hsa-miR-520f hsa-miR-30d hsa-miR-30a hsa-miR-629* hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC20 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC20

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    GenScript: all cDNA clones in your preferred vector: ZDHHC20 (NM_153251)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC20

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC20


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZDH20_HUMAN, Q5W0Z9: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA16647879
    GO:0016021integral component of membrane IEA--

    ZDHHC20 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC20
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC20

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for ZDHHC20 (ENSP000003719054) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1ENSP000003444564STRING: ENSP00000344456
    JUPENSP000003111134STRING: ENSP00000311113
    UBCENSP000003448184STRING: ENSP00000344818
    TMEM35ENSP000003620214STRING: ENSP00000362021
    DLG2ENSP000003652724STRING: ENSP00000365272
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018345protein palmitoylation IDA--

    ZDHHC20 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC20 (ZDH20)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZDHHC20 gene (2 alternative transcripts): 
    NM_001286638.1  NM_153251.3  

    Unigene Cluster for ZDHHC20:

    Zinc finger, DHHC-type containing 20
    Hs.564611  [show with all ESTs]
    Unigene Representative Sequence: NM_153251
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000400590(uc001uoa.2 uc001uod.3 uc001uoc.3 uc001uoe.3 uc010tcs.2)
    ENST00000464055 ENST00000477811 ENST00000494731 ENST00000484277 ENST00000382466
    ENST00000542645 ENST00000415724 ENST00000320220 ENST00000422251
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZDHHC20 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC20 (see all 78):
    hsa-miR-411* hsa-miR-548j hsa-miR-3607-3p hsa-miR-520f hsa-miR-30d hsa-miR-30a hsa-miR-629* hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC20 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZDHHC20
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC20
    Clone
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    OriGene clones in human, mouse for ZDHHC20 (see all 6)
    OriGene ORF clones in mouse, rat for ZDHHC20
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZDHHC20 (NM_153251)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC20
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC20
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC20
      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC20
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC20

    Additional mRNA sequence: 

    AK090979.1 AK299354.1 AL833626.1 BC034944.1 BC036691.1 BC037336.1 BC050367.1 

    15 DOTS entries:

    DT.75166788  DT.100784012  DT.116238  DT.120784063  DT.101962807  DT.101979037  DT.75149530  DT.120784460 
    DT.100725915  DT.95363371  DT.100724784  DT.120783856  DT.120784025  DT.100690507  DT.120784392 

    Selected AceView cDNA sequences (see all 171):

    BC050367 BG571281 BM807303 BM126657 AA827058 BX490149 NM_153251 AA454190 
    BM126922 AA383635 AL833626 CA446645 BC034944 R71043 BE350064 AK090979 
    AI640293 BE463631 AA731630 AA298278 AI951066 AI572845 BX480028 AA765809 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC20 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c
    SP1:                                                                                            -                     
    SP2:                                                              -                                                   
    SP3:                    -                                         -                 -           -                     
    SP4:                                                              -                 -           -                     
    SP5:        -           -                                                                                             


    ECgene alternative splicing isoforms for ZDHHC20

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZDHHC20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACACAGAAC
    ZDHHC20 Expression
    About this image


    ZDHHC20 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    ZDHHC20 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC20 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.564611
        Custom PCR Arrays for ZDHHC20
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZDHHC20 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc201 , 5 zinc finger, DHHC domain containing 201, 5 89.99(n)1
    92.07(a)1
      14 (30.51 cM)5
    759651  NM_029492.41  NP_083768.41 
     578327025 
    chicken
    (Gallus gallus)
    Aves ZDHHC201 zinc finger, DHHC-type containing 20 78.74(n)
    79.49(a)
      418947  XM_004938807.1  XP_004938864.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC206
    zinc finger, DHHC-type containing 20
    70(a)
    1 ↔ 1
    3(187801518-187856033)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia zdhhc201 zinc finger, DHHC-type containing 2 70.09(n)
    72.93(a)
      549883  NM_001017129.2  NP_001017129.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1627231 zgc:162723 64.07(n)
    67.66(a)
      561776  NM_001083549.1  NP_001077018.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG14071 CG1407 53.79(n)
    53.45(a)
      36043  NM_001273914.1  NP_001260843.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dhhc-46
    spe-106
    Protein SPE-10 (spe-10) mRNA, complete cds
    32(a)
    31(a)
    many ↔ many
    many ↔ many
    III(9863252-9867786) WBGene00014075
    V(10384157-10385711) WBGene00004964
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFA36
    Palmitoyltransferase for Vac8p, required for vacuo...
    27(a)
    1 → many
    XIV(27337-28347) YNL326C
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SMO1-31 SMO1-3 48.64(n)
    37.41(a)
      828373  NM_001203872.1  NP_001190801.1 
    rice
    (Oryza sativa)
    Liliopsida Os10g05452001 Os10g0545200   --   4349278  NM_001071741.1  NP_001065206.1 


    ENSEMBL Gene Tree for ZDHHC20 (if available)
    TreeFam Gene Tree for ZDHHC20 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZDHHC20 gene
    ZDHHC212  ZDHHC32  ZDHHC72  ZDHHC162  ZDHHC62  ZDHHC22  ZDHHC152  
    2 SIMAP similar genes for ZDHHC20 using alignment to 5 protein entries:     ZDH20_HUMAN (see all proteins):
    ZDHHC2    ZDHHC15

    ZDHHC20 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for ZDHHC20
    PGOHUM00000242372 PGOHUM00000248624 PGOHUM00000243125 PGOHUM00000243583


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZDHHC20 (see all 1328)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs95507321,2
    C,F,A--21967590(+) GCCAAG/TATCGC 1 -- int13Minor allele frequency- T:0.50NA 6
    rs1447632161,2
    C--21967812(+) CACTCC/TAGCCT 1 -- int10--------
    rs1475839061,2
    C--21967839(+) AAAAA-/AAAAA 
            
    GGTAC
    1 -- int10--------
    rs1815562111,2
    --21967982(+) ACCTGC/TGCTGG 1 -- int10--------
    rs95096781,2
    C,F--21967983(+) cctgcG/Actggg 1 -- int16Minor allele frequency- A:0.13NA WA CSA 246
    rs1862756131,2
    --21968135(+) CAGCCA/GGGATG 1 -- int10--------
    rs1166530091,2
    C,F--21968233(+) AAATCA/GGATCA 1 -- int11Minor allele frequency- G:0.14WA 118
    rs1172821881,2
    C,F--21968268(+) AGCCAC/AAGTCA 1 -- int11Minor allele frequency- A:0.02NA 120
    rs740393191,2
    C,F--21968308(+) TTTGGC/GCCCCT 1 -- int12Minor allele frequency- G:0.12WA 120
    rs1403514751,2
    C--21968312(+) GCCCCC/TTCTTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for ZDHHC20 (21946710 - 22033509 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZDHHC20:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668027CNV Deletion23128226
    esv1388531CNV Insertion17803354
    esv992961CNV Insertion20482838
    esv28175CNV Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for ZDHHC20:    
    About MalaCards
    malaria


    ZDHHC20 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZDHHC20

    Export disorders for ZDHHC20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZDHHC20 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with ZDHHC20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PubMed id 23400010)1 Del-Aguila J.L....Boerwinkle E. (Pharmacogenomics J. 2013)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. DHHC20: a human palmitoyl acyltransferase that causes cellular transformation. (PubMed id 20334580)1 Draper J.M. and Smith C.D. (Mol. Membr. Biol. 2010)
    9. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 253832 HGNC: 20749 AceView: FLJ25952 Ensembl:ENSG00000180776 euGenes: HUgn253832
    ECgene: ZDHHC20 H-InvDB: ZDHHC20

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZDHHC20 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZDHHC20 gene:
    Search GeneIP for patents involving ZDHHC20

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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