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Aliases for ZDHHC20 Gene

Aliases for ZDHHC20 Gene

  • Zinc Finger, DHHC-Type Containing 20 2 3
  • Zinc Finger DHHC Domain-Containing Protein 20 3 4
  • DHHC-20 3 4
  • Probable Palmitoyltransferase ZDHHC20 3
  • 4933421L13Rik 3
  • EC 2.3.1.225 4
  • EC 2.3.1 63

External Ids for ZDHHC20 Gene

Previous GeneCards Identifiers for ZDHHC20 Gene

  • GC00U907486
  • GC13M020845
  • GC13M020826
  • GC13M021950
  • GC13M002751

Summaries for ZDHHC20 Gene

GeneCards Summary for ZDHHC20 Gene

ZDHHC20 (Zinc Finger, DHHC-Type Containing 20) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC7.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZDHHC20 Gene

Genomics for ZDHHC20 Gene

Regulatory Elements for ZDHHC20 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZDHHC20 Gene

Start:
21,372,571 bp from pter
End:
21,459,370 bp from pter
Size:
86,800 bases
Orientation:
Minus strand

Genomic View for ZDHHC20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZDHHC20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZDHHC20 Gene

Proteins for ZDHHC20 Gene

  • Protein details for ZDHHC20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5W0Z9-ZDH20_HUMAN
    Recommended name:
    Probable palmitoyltransferase ZDHHC20
    Protein Accession:
    Q5W0Z9
    Secondary Accessions:
    • A8MTV9
    • C9JG20
    • I6L9D4
    • Q2TB82
    • Q6NVU8

    Protein attributes for ZDHHC20 Gene

    Size:
    365 amino acids
    Molecular mass:
    42278 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZDHHC20 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZDHHC20 Gene

Proteomics data for ZDHHC20 Gene at MOPED

Selected DME Specific Peptides for ZDHHC20 Gene

Post-translational modifications for ZDHHC20 Gene

  • Ubiquitination at Lys96 and Lys123
  • Modification sites at PhosphoSitePlus

Other Protein References for ZDHHC20 Gene

Domains for ZDHHC20 Gene

Gene Families for ZDHHC20 Gene

HGNC:
  • ZDHHC :Zinc fingers, DHHC-type

Protein Domains for ZDHHC20 Gene

Graphical View of Domain Structure for InterPro Entry

Q5W0Z9

UniProtKB/Swiss-Prot:

ZDH20_HUMAN :
  • Q5W0Z9
Domain:
  • The DHHC domain is required for palmitoyltransferase activity.
Family:
  • Belongs to the DHHC palmitoyltransferase family.
Similarity:
  • Contains 1 DHHC-type zinc finger.
genes like me logo Genes that share domains with ZDHHC20: view

Function for ZDHHC20 Gene

Molecular function for ZDHHC20 Gene

UniProtKB/Swiss-Prot CatalyticActivity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

Enzyme Numbers (IUBMB) for ZDHHC20 Gene

Gene Ontology (GO) - Molecular Function for ZDHHC20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0016409 palmitoyltransferase activity IDA 23034182
GO:0019706 protein-cysteine S-palmitoyltransferase activity IEA --
genes like me logo Genes that share ontologies with ZDHHC20: view

Phenotypes for ZDHHC20 Gene

genes like me logo Genes that share phenotypes with ZDHHC20: view

Animal Model Products

CRISPR Products

miRNA for ZDHHC20 Gene

miRTarBase miRNAs that target ZDHHC20

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZDHHC20

In Situ Assay Products

Flow Cytometry Products

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for ZDHHC20 Gene

Localization for ZDHHC20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZDHHC20 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZDHHC20 Gene COMPARTMENTS Subcellular localization image for ZDHHC20 gene
Compartment Confidence
plasma membrane 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZDHHC20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA 16647879
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ZDHHC20: view

Pathways for ZDHHC20 Gene

SuperPathways for ZDHHC20 Gene

No Data Available

Interacting Proteins for ZDHHC20 Gene

Gene Ontology (GO) - Biological Process for ZDHHC20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
GO:0018345 protein palmitoylation IDA 23034182
genes like me logo Genes that share ontologies with ZDHHC20: view

No data available for Pathways by source for ZDHHC20 Gene

Transcripts for ZDHHC20 Gene

Unigene Clusters for ZDHHC20 Gene

Zinc finger, DHHC-type containing 20:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZDHHC20

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZDHHC20

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC20 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c
SP1: -
SP2: -
SP3: - - - -
SP4: - - -
SP5: - -
SP6: -

Relevant External Links for ZDHHC20 Gene

GeneLoc Exon Structure for
ZDHHC20
ECgene alternative splicing isoforms for
ZDHHC20

Expression for ZDHHC20 Gene

mRNA expression in normal human tissues for ZDHHC20 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZDHHC20 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (4.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZDHHC20 Gene

SOURCE GeneReport for Unigene cluster for ZDHHC20 Gene Hs.564611

genes like me logo Genes that share expressions with ZDHHC20: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZDHHC20 Gene

Orthologs for ZDHHC20 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZDHHC20 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZDHHC20 35
  • 99.44 (n)
  • 99.72 (a)
ZDHHC20 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZDHHC20 35
  • 91.69 (n)
  • 92.38 (a)
ZDHHC20 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZDHHC20 35
  • 93.5 (n)
  • 94.35 (a)
ZDHHC20 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zdhhc20 35
  • 89.99 (n)
  • 92.07 (a)
Zdhhc20 16
Zdhhc20 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZDHHC20 36
  • 62 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZDHHC20 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zdhhc20 35
  • 90.45 (n)
  • 91.98 (a)
chicken
(Gallus gallus)
Aves ZDHHC20 35
  • 78.74 (n)
  • 79.49 (a)
ZDHHC20 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZDHHC20 36
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zdhhc20 35
  • 70.09 (n)
  • 72.93 (a)
zebrafish
(Danio rerio)
Actinopterygii ZDHHC20 (1 of 2) 36
  • 63 (a)
OneToMany
ZDHHC20 (2 of 2) 36
  • 58 (a)
OneToMany
zgc:162723 35
  • 64.07 (n)
  • 67.66 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004938 35
  • 53.99 (n)
  • 50.35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1407 35
  • 53.79 (n)
  • 53.45 (a)
CG1407 36
  • 37 (a)
ManyToMany
CG17287 36
  • 36 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea dhhc-4 36
  • 32 (a)
ManyToMany
spe-10 36
  • 31 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PFA3 36
  • 27 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons SMO1-3 35
  • 48.64 (n)
  • 37.41 (a)
rice
(Oryza sativa)
Liliopsida Os10g0545200 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 45 (a)
OneToMany
Species with no ortholog for ZDHHC20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZDHHC20 Gene

ENSEMBL:
Gene Tree for ZDHHC20 (if available)
TreeFam:
Gene Tree for ZDHHC20 (if available)

Paralogs for ZDHHC20 Gene

Paralogs for ZDHHC20 Gene

Selected SIMAP similar genes for ZDHHC20 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZDHHC20 Gene

genes like me logo Genes that share paralogs with ZDHHC20: view

Variants for ZDHHC20 Gene

Sequence variations from dbSNP and Humsavar for ZDHHC20 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs1073039 -- 21,437,423(-) gcagc(A/G)agcat intron-variant
rs1080426 -- 21,429,454(-) GAAAC(C/T)GTGGA intron-variant
rs1148971 -- 21,432,353(+) gagac(A/G)gagtc intron-variant
rs1148972 -- 21,444,791(+) TGGCT(C/G)ATGTC intron-variant
rs1148973 -- 21,453,399(-) cttgc(C/T)ttcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZDHHC20 Gene

Variant ID Type Subtype PubMed ID
esv992961 CNV Insertion 20482838
esv28175 CNV Loss 19812545
esv2668027 CNV Deletion 23128226
esv1388531 CNV Insertion 17803354

Relevant External Links for ZDHHC20 Gene

HapMap Linkage Disequilibrium report
ZDHHC20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZDHHC20 Gene

Disorders for ZDHHC20 Gene

Relevant External Links for ZDHHC20

Genetic Association Database (GAD)
ZDHHC20
genes like me logo Genes that share disorders with ZDHHC20: view

No data available for UniProtKB/Swiss-Prot for ZDHHC20 Gene

Publications for ZDHHC20 Gene

  1. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. (PMID: 16647879) Ohno Y. … Igarashi Y. (Biochim. Biophys. Acta 2006) 3
  4. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3
  5. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3

Products for ZDHHC20 Gene

  • antibodies-online peptides for ZDHHC20
  • antibodies-online antibodies for ZDHHC20
  • antibodies-online kits for ZDHHC20

Sources for ZDHHC20 Gene

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