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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZDHHC2 Gene

protein-coding   GIFtS: 52
GCID: GC08P017058

zinc finger, DHHC-type containing 2
 Explore 5 diseases affiliated with
ZDHHC2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ZDHHC2    

Aliases
for ZDHHC2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Zinc Finger, DHHC-Type Containing 21 2     Ream3
ZNF3721 2 3     Rec3
Reduced Expression Associated With Metastasis Protein2 3     Zinc Finger, DHHC Domain Containing 22
Reduced Expression In Cancer Protein2 3     EC 2.3.1.-3
Zinc Finger DHHC Domain-Containing Protein 22 3     REAM3
Zinc Finger Protein 3722 3     REC3
DHHC-22 3     Ream3
DHHC22     Rec3
Palmitoyltransferase ZDHHC22     EC 2.3.18

External Ids:    HGNC: 184691   Entrez Gene: 512012   Ensembl: ENSG000001042197   UniProtKB: Q9UIJ53   

Export aliases for ZDHHC2 gene to outside databases

Previous GC identifers: GC08P016907 GC08P017093 GC08P017024 GC08P017023 GC08P015559


Summaries
for ZDHHC2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ZDHC2_HUMAN, Q9UIJ5
Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity)

Gene Wiki entry for ZDHHC2


Genomic Views
for ZDHHC2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZDHHC2 gene promoter:
         GATA-3   AP-1   ATF-2   MEF-2A   POU2F1   POU2F1a   c-Jun   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZDHHC2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZDHHC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZDHHC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p22   Ensembl cytogenetic band:  8p22   HGNC cytogenetic band: 8p22

ZDHHC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P017058:  view genomic region     (about GC identifiers)

Start:
 17,013,538 bp from pter      End:
 17,082,308 bp from pter
Size:
 68,771 bases      Orientation:
 plus strand

Proteins
for ZDHHC2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZDHC2_HUMAN, Q9UIJ5 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC2  
Size: 367 amino acids; 42022 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: D3DSP5

Explore the universe of human proteins at neXtProt for ZDHHC2: NX_Q9UIJ5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UIJ5

    • 4/5 DME Specific Peptides for ZDHHC2 (Q9UIJ5) (see all 5)
     MDHHCPW  CILKMDH  NYKFFLLFL  KPDRCHHCS 

    ZDHHC2 Protein expression data from MOPED and PaxDb:    About this image 
    ZDHHC2 Protein Expression
    REFSEQ proteins: NP_057437.1  
    ENSEMBL proteins: 
     ENSP00000262096   ENSP00000430804   ENSP00000430317  

    Human Recombinant Protein Products for ZDHHC2: 
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    Novus Biologicals ZDHHC2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ZDHHC2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    ZDHHC2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ZDHHC2

    Protein Domains /
    Families
    for ZDHHC2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZDHHC2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q9UIJ5

    ProtoNet protein and cluster: Q9UIJ5

    1 Blocks protein family: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDHC2_HUMAN, Q9UIJ5
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    Function
    for ZDHHC2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDHC2_HUMAN, Q9UIJ5
    Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity)
    Catalytic activity: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA

         Enzyme Numbers (IUBMB): EC 2.3.12 EC 2.3.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IEA--
         
    ZDHHC2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ZDHHC2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZDHHC2
    8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate ZDHHC2 (see all 34):
    hsa-miR-3152-3p hsa-miR-300 hsa-miR-219-5p hsa-miR-301a hsa-miR-624 hsa-miR-218 hsa-miR-374c hsa-miR-548m
    SwitchGear 3'UTR luciferase reporter plasmid: ZDHHC2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of ZDHHC2 
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC2


    Pathways & Interactions
    for ZDHHC2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZDHHC2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for ZDHHC2 (Q9UIJ53 ENSP000002620964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAFBQ9Y5Q33, ENSP000003624104I2D: score=1 STRING: ENSP00000362410
    MSX2P355483, ENSP000002392434I2D: score=1 STRING: ENSP00000239243
    DLG4P783523I2D: score=1 
    TMEM35Q53FP23I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018345protein palmitoylation IEA--

    ZDHHC2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZDHHC2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZDHHC2
    Search CenterWatch for drugs/clinical trials and news about ZDHHC2 / ZDHC2 

    Transcripts
    for ZDHHC2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ZDHHC2 gene: 
    NM_016353.4  

    Unigene Cluster for ZDHHC2:

    Zinc finger, DHHC-type containing 2
    Hs.744097  [show with all ESTs]
    Unigene Representative Sequence: AL833080
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262096(uc003wxe.3) ENST00000523132 ENST00000522184 ENST00000517334


    miRNA
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    8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate ZDHHC2 (see all 34):
    hsa-miR-3152-3p hsa-miR-300 hsa-miR-219-5p hsa-miR-301a hsa-miR-624 hsa-miR-218 hsa-miR-374c hsa-miR-548m
    SwitchGear 3'UTR luciferase reporter plasmid: ZDHHC2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZDHHC2 (see all 7)
    OriGene shRNA RFP: ZDHHC2
    OriGene siRNA: ZDHHC2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZDHHC2
    Sirion Biotech Custom design and validation of potent shRNA sequences against ZDHHC2 
    Clone
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    GenScript: all cDNA clones in your preferred vector: ZDHHC2 (NM_016353)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZDHHC2

    Additional cDNA sequence: 

    AB023584.1 AK001608.1 AK126190.1 AL833080.1 BC039253.1 BC050272.1 

    7 DOTS entries:

    DT.443826  DT.440633  DT.100841593  DT.95272420  DT.100702824  DT.99987765  DT.95272421 

    24/129 AceView cDNA sequences (see all 129):

    AU130929 AI688634 CB109103 CR598335 AA777386 AW440609 AW297238 AI619547 
    BE671069 CR591508 BU169423 AA931887 AW473630 BF110784 CB123863 AI337674 
    AA781969 AI123822 AL597207 AI207121 AA461348 BM128097 CR626790 AW614265 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:        -                                                     -                                 
    SP2:                                                              -           -                     
    SP3:                                                                                                
    SP4:                                                                                                


    ECgene alternative splicing isoforms for ZDHHC2

    Expression
    for ZDHHC2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZDHHC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATTCACTCC
    ZDHHC2 Expression
    About this image

    ZDHHC2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    10/12 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 12) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    Spinal CordSpinal Dorsal ColumnsDorsal Spinal Cord Progenitor CellsSpinal Cord
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainHypothalamusBrain
    BrainMedulla OblongataBrain
    BrainMidbrain tegmentumBrain
    BrainStriatumBrain
    BrainThalamusBrain
    Neural TubeMetencephalonNeural Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)

    See ZDHHC2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZDHHC2

    SOURCE GeneReport for Unigene cluster: Hs.744097

    UniProtKB/Swiss-Prot: ZDHC2_HUMAN, Q9UIJ5
    Tissue specificity: Ubiquitously expressed. Reduced expression in colorectal cancers with liver metastasis

        SABiosciences Custom PCR Arrays for ZDHHC2
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    In Situ
    Assay Products:     
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    Orthologs
    for ZDHHC2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZDHHC2 gene from 8/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ZDHHC26
    		 Uncharacterized protein
    		 83(a)
    		 1 ↔ 1
    		 4(65025339-65052669)
    lizard
    (Anolis carolinensis)    		 Reptilia ZDHHC26
    		 --
    		 80(a)
    		 1 ↔ 1
    		 5(108170566-108205813)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.191302 Xenopus laevis transcribed sequence with moderate similarity more 82.09(n)    BJ066084.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zdhhc21 zinc finger, DHHC-type containing 2 70.28(n)
    75.83(a)    		   541365  NM_001013492.1  NP_001013510.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG14073   -- 50(a)
    (best of 2)    		     --
    worm
    (Caenorhabditis elegans)    		 Secernentea ZK757.13
    ZK757.41    		 Protein ZK757.41 38(a)3
    49.37(n)1
    40.31(a)1    		   III(9936543-9942821)3
    1914201  NM_001027862.21  NP_001023033.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT4G008401 putative S-acyltransferase 48.85(n)
    36.54(a)    		   826193  NM_116310.4  NP_567193.2 
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 transposon protein, putative, unclassified, expres...
    DHHC zinc finger domain containing protein, expres...
    		 30(a)
    28(a)
    		 possible ortholog
    possible ortholog
    		 7(16649384-16656253)
    3(33563383-33569015)


    ENSEMBL Gene Tree for ZDHHC2 (if available)
    TreeFam Gene Tree for ZDHHC2 (if available) 

    Paralogs
    for ZDHHC2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZDHHC2 gene
    ZDHHC212  ZDHHC32  ZDHHC72  ZDHHC202  ZDHHC232  ZDHHC152  
    9 SIMAP similar genes for ZDHHC2 using alignment to 2 protein entries:     ZDHC2_HUMAN (see all proteins):
    ZDHHC3    ZDHHC20    ZDHHC14    ZDHHC5    ZDHHC15    ZDHHC18
    ZDHHC7    ZDHHC1    ZDHHC8

    ZDHHC2 for paralogs           About GeneDecksing



    Genomic Variants
    for ZDHHC2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1477 NCBI SNPs in ZDHHC2 are shown (see all 1477)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1923957901,2
    		--17011864(+) GAAAAG/TAAATC 1 -- us2k10--------
    rs284885591,2
    		--17011868(+) ATAAAC/TCAAAG 1 -- us2k10--------
    rs1849893121,2
    		--17011902(+) GCTCTC/TCTTCC 1 -- us2k10--------
    rs1889782041,2
    		--17011990(+) TTAGAA/GACTAC 1 -- us2k10--------
    rs1468999471,2
    		--17012188(+) TAGATA/GAGTAA 1 -- us2k10--------
    rs1818557911,2
    		--17012219(+) AGATAC/TGACAC 1 -- us2k10--------
    rs29046581,2
    		C,F,A,H--17012250(+) GTAGAC/TGATGT 1 -- us2k114Minor allele frequency- T:0.24NS EA NA WA 790
    rs1479643781,2
    		--17012263(+) AAACTC/GGGCAG 1 -- us2k10--------
    rs1848800301,2
    		--17012315(+) GAGAGC/GAGGAA 1 -- us2k10--------
    rs38086471,2
    		C,F--17012336(-) ATGCGA/GCGATG 1 -- us2k16Minor allele frequency- G:0.29NA WA EA 364

    HapMap Linkage Disequilibrium report for ZDHHC2 (17013538 - 17082308 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ZDHHC2: --

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    Disorders / Diseases
    for ZDHHC2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ZDHHC2 for disorders           About GeneDecksing

    UniProtKB/Swiss-Prot: ZDHC2_HUMAN, Q9UIJ5
  • Note=Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer

    • 5 diseases for ZDHHC2:    About MalaCards
    cystitis    hepatocellular carcinoma    colorectal cancer    carcinoma
    malaria

    2 diseases from the University of Copenhagen DISEASES database for ZDHHC2:
    Interstitial cystitis     Chronic interstitial cystitis
    Human Genome Epidemiology (HuGE) Navigator: ZDHHC2 (1 document)

    Export disorders for ZDHHC2 gene to outside databases

    Publications
    for ZDHHC2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZDHHC2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ZDHHC2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis. (PubMed id 10918388)1, 2, 3 Oyama T.... Nakamura Y. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The palmitoyl transferase DHHC2 targets a dynamic mem brane cycling pathway: regulation by a C-terminal domain. (PubMed id 21471008)1 Greaves J....Chamberlain L.H. (2011)
    4. Gi/o signaling and the palmitoyltransferase DHHC2 reg ulate palmitate cycling and shuttling of RGS7 family-binding protein. (PubMed id 21343290)1 Jia L....Blumer K.J. (2011)
    5. DHHC2 is a protein S-acyltransferase for Lck. (PubMed id 22034844)1 Zeidman R....Magee A.I. (2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    8. Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling. (PubMed id 19144824)1 Planey S.L....Zacharias D.A. (2009)
    9. Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method. (PubMed id 18296695)1 Zhang J....Zacharias D.A. (2008)
    10. DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151. (PubMed id 18508921)1 Sharma C....Hemler M.E. (2008)

    External Searches for ZDHHC2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing ZDHHC2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51201 HGNC: 18469 AceView: ZDHHC2 Ensembl:ENSG00000104219 euGenes: HUgn51201
    ECgene: ZDHHC2 H-InvDB: ZDHHC2

    Other Databases showing ZDHHC2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ZDHHC2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZDHHC2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ZDHHC2 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for ZDHHC2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ZDHHC2 gene:
    Search GeneIP for patents involving ZDHHC2

    GeneCards and IP:
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