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Aliases for ZDHHC19 Gene

Aliases for ZDHHC19 Gene

  • Zinc Finger, DHHC-Type Containing 19 2 3
  • Zinc Finger DHHC Domain-Containing Protein 19 3 4
  • DHHC-19 3 4
  • Zinc Finger, DHHC Domain Containing 19 3
  • Probable Palmitoyltransferase ZDHHC19 3
  • EC 2.3.1.225 4
  • DHHC19 3

External Ids for ZDHHC19 Gene

Summaries for ZDHHC19 Gene

GeneCards Summary for ZDHHC19 Gene

ZDHHC19 (Zinc Finger, DHHC-Type Containing 19) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZDHHC19 Gene

Genomics for ZDHHC19 Gene

Genomic Location for ZDHHC19 Gene

Start:
196,197,449 bp from pter
End:
196,211,437 bp from pter
Size:
13,989 bases
Orientation:
Minus strand

Genomic View for ZDHHC19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZDHHC19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZDHHC19 Gene

Regulatory Elements for ZDHHC19 Gene

Proteins for ZDHHC19 Gene

  • Protein details for ZDHHC19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WVZ1-ZDH19_HUMAN
    Recommended name:
    Probable palmitoyltransferase ZDHHC19
    Protein Accession:
    Q8WVZ1
    Secondary Accessions:
    • A8MSY6
    • B3KVI1

    Protein attributes for ZDHHC19 Gene

    Size:
    309 amino acids
    Molecular mass:
    34352 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZDHHC19 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZDHHC19 Gene

Proteomics data for ZDHHC19 Gene at MOPED

Post-translational modifications for ZDHHC19 Gene

No Post-translational modifications

Other Protein References for ZDHHC19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZDHHC19 Gene

Domains for ZDHHC19 Gene

Gene Families for ZDHHC19 Gene

HGNC:
  • ZDHHC :Zinc fingers, DHHC-type

Protein Domains for ZDHHC19 Gene

UniProtKB/Swiss-Prot:

ZDH19_HUMAN
Domain:
  • The DHHC domain is required for palmitoyltransferase activity.:
    • Q8WVZ1
Family:
  • Belongs to the DHHC palmitoyltransferase family.:
    • Q8WVZ1
Similarity:
  • Contains 1 DHHC-type zinc finger.:
    • Q8WVZ1
genes like me logo Genes that share domains with ZDHHC19: view

Function for ZDHHC19 Gene

Molecular function for ZDHHC19 Gene

UniProtKB/Swiss-Prot CatalyticActivity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

Enzyme Numbers (IUBMB) for ZDHHC19 Gene

Gene Ontology (GO) - Molecular Function for ZDHHC19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0019706 protein-cysteine S-palmitoyltransferase activity IEA --
genes like me logo Genes that share ontologies with ZDHHC19: view

miRNA for ZDHHC19 Gene

miRTarBase miRNAs that target ZDHHC19

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZDHHC19 Gene

Localization for ZDHHC19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZDHHC19 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZDHHC19 Gene COMPARTMENTS Subcellular localization image for ZDHHC19 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for ZDHHC19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA 16647879
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ZDHHC19: view

Pathways for ZDHHC19 Gene

SuperPathways for ZDHHC19 Gene

No Data Available

Interacting Proteins for ZDHHC19 Gene

Gene Ontology (GO) - Biological Process for ZDHHC19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ZDHHC19: view

No data available for Pathways by source for ZDHHC19 Gene

Transcripts for ZDHHC19 Gene

Unigene Clusters for ZDHHC19 Gene

Zinc finger, DHHC-type containing 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC19 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10
SP1: - -
SP2: - - -
SP3: - - -
SP4:

Relevant External Links for ZDHHC19 Gene

GeneLoc Exon Structure for
ZDHHC19
ECgene alternative splicing isoforms for
ZDHHC19

Expression for ZDHHC19 Gene

mRNA expression in normal human tissues for ZDHHC19 Gene

mRNA differential expression in normal tissues according to GTEx for ZDHHC19 Gene

This gene is overexpressed in Whole Blood (31.6) and Testis (12.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZDHHC19 Gene

SOURCE GeneReport for Unigene cluster for ZDHHC19 Gene Hs.111591

genes like me logo Genes that share expressions with ZDHHC19: view

Orthologs for ZDHHC19 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZDHHC19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZDHHC19 36
  • 98.71 (n)
  • 98.06 (a)
ZDHHC19 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZDHHC19 36
  • 86.29 (n)
  • 84.62 (a)
ZDHHC19 37
  • 70 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZDHHC19 36
  • 86.88 (n)
  • 84.62 (a)
ZDHHC19 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zdhhc19 36
  • 75.97 (n)
  • 69.81 (a)
Zdhhc19 16
Zdhhc19 37
  • 62 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZDHHC19 37
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZDHHC19 37
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zdhhc19 36
  • 75.6 (n)
  • 69.61 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ERF2 37
  • 15 (a)
OneToMany
Species with no ortholog for ZDHHC19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZDHHC19 Gene

ENSEMBL:
Gene Tree for ZDHHC19 (if available)
TreeFam:
Gene Tree for ZDHHC19 (if available)

Paralogs for ZDHHC19 Gene

Selected SIMAP similar genes for ZDHHC19 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZDHHC19: view

Variants for ZDHHC19 Gene

Sequence variations from dbSNP and Humsavar for ZDHHC19 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs939891 -- 196,199,219(+) AAGTC(C/G)TCCCC intron-variant
rs939892 -- 196,199,363(+) GCCTT(C/T)GCTGT intron-variant
rs1105977 -- 196,202,381(+) CGCCT(G/T)TTCAG intron-variant
rs1105978 -- 196,202,509(+) GGACG(C/T)ACTGC intron-variant
rs1106479 -- 196,198,484(+) GCCAC(C/T)GTCCT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZDHHC19 Gene

Variant ID Type Subtype PubMed ID
dgv1549e1 CNV Complex 17122850
nsv878171 CNV Gain 21882294
nsv878174 CNV Loss 21882294
nsv878175 CNV Loss 21882294
esv32936 CNV Gain 17666407
nsv878176 CNV Gain 21882294
esv2662732 CNV Deletion 23128226
nsv878177 CNV Loss 21882294
dgv5372n71 CNV Gain 21882294
esv2726575 CNV Deletion 23290073

Relevant External Links for ZDHHC19 Gene

HapMap Linkage Disequilibrium report
ZDHHC19

Disorders for ZDHHC19 Gene

Relevant External Links for ZDHHC19

Genetic Association Database (GAD)
ZDHHC19
Human Genome Epidemiology (HuGE) Navigator
ZDHHC19
genes like me logo Genes that share disorders with ZDHHC19: view

No data available for UniProtKB/Swiss-Prot for ZDHHC19 Gene

Publications for ZDHHC19 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population. (PMID: 21160409) Petrovski S. … Goldstein D.B. (AIDS 2011) 3 49
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for ZDHHC19 Gene

Sources for ZDHHC19 Gene

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