Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZDHHC16 Gene

protein-coding   GIFtS: 49
GCID: GC10P099195

Zinc Finger, DHHC-Type Containing 16

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger, DHHC-Type Containing 161 2     Probable Palmitoyltransferase ZDHHC162
Zinc Finger DHHC Domain-Containing Protein 162 3     Zinc Finger, DHHC Domain Containing 162
DHHC-162 3     EC 2.3.1.2253
APH22     EC 2.3.18
Abl-Philin 22     

External Ids:    HGNC: 207141   Entrez Gene: 842872   Ensembl: ENSG000001713077   UniProtKB: Q969W13   

Export aliases for ZDHHC16 gene to outside databases

Previous GC identifers: GC10P098439 GC10P099337 GC10P098870 GC10P092831


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ZDHHC16 Gene:
ZDHHC16 (zinc finger, DHHC-type containing 16) is a protein-coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC21.

UniProtKB/Swiss-Prot: ZDH16_HUMAN, Q969W1
Function: May be involved in apoptosis regulation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC16 gene promoter:
         SRY   AML1a   Tal-1beta   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC16 promoter sequence
   Search Chromatin IP Primers for ZDHHC16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.1   Ensembl cytogenetic band:  10q24.1   HGNC cytogenetic band: 10q24.1

ZDHHC16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC16 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P099195:  view genomic region     (about GC identifiers)

Start:
99,205,927 bp from pter      End:
99,217,127 bp from pter
Size:
11,201 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZDH16_HUMAN, Q969W1 (See protein sequence)
Recommended Name: Probable palmitoyltransferase ZDHHC16  
Size: 377 amino acids; 43633 Da
Subunit: Interacts with ABL1 (By similarity)
Secondary accessions: D3DR52 D3DR53 D3DR54 Q5JTG7 Q5JTH0 Q8N4Z6 Q8WY84 Q9BSV3
Alternative splicing: 4 isoforms:  Q969W1-1   Q969W1-2   Q969W1-3   Q969W1-4   

Explore the universe of human proteins at neXtProt for ZDHHC16: NX_Q969W1

Explore proteomics data for ZDHHC16 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ZDHHC16 (Q969W1) (see all 12)
     WLNNCVG  MDHHCPW  TVSICKKCI  CVLKMDHHC 


    See ZDHHC16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001274732.1  NP_001274733.1  NP_115703.2  NP_932160.1  NP_932161.1  NP_932162.1  NP_932163.1  

    ENSEMBL proteins: 
     ENSP00000359891   ENSP00000400719   ENSP00000359883   ENSP00000345383   ENSP00000323360  
     ENSP00000359879   ENSP00000304487   ENSP00000398532   ENSP00000405240   ENSP00000396286  
     ENSP00000377357  

    ZDHHC16 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ZDHHC16
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZDHHC16
    GenScript Custom Purified and Recombinant Proteins Services for ZDHHC16
    Novus Biologicals ZDHHC16 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZDHHC16

     
    Search eBioscience for Proteins for ZDHHC16 

    ZDHHC16 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZDHHC16
    Novus Biologicals ZDHHC16 Antibodies
    Abcam antibodies for ZDHHC16
    Cloud-Clone Corp. Antibodies for ZDHHC16
    Search ThermoFisher Antibodies for ZDHHC16
    LSBio Antibodies in human, mouse, rat for ZDHHC16

    ZDHHC16 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZDHHC16
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZDHHC16
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZDHHC16
    Cloud-Clone Corp. CLIAs for ZDHHC16
    Search eBioscience for ELISAs for ZDHHC16 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q969W1

    ProtoNet protein and cluster: Q969W1

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDH16_HUMAN, Q969W1
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC16           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDH16_HUMAN, Q969W1
    Function: May be involved in apoptosis regulation (By similarity)
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0016746transferase activity, transferring acyl groups ----
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    Find genes that share ontologies with ZDHHC16           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for ZDHHC16:
     Increased HPV18 LCR reporter a  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZDHHC16

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ZDHHC16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC16 (see all 9):
    hsa-miR-22 hsa-miR-34c-5p hsa-miR-146b-3p hsa-miR-449b hsa-miR-1267 hsa-miR-449a hsa-miR-34a hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC16 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZDHHC16
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC16

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZDHHC16

    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC16 (see all 27)
    OriGene ORF clones in mouse, rat for ZDHHC16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): ZDHHC16 (NM_032327)
    Sino Biological Human cDNA Clone for ZDHHC16
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC16

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZDHHC16
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC16 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZDH16_HUMAN, Q969W1: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    plasma membrane3
    golgi apparatus1
    lysosome1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ZDHHC16           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC16
    Interactions:

        GeneGlobe Interaction Network for ZDHHC16

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for ZDHHC16 (Q969W13 ENSP000003598914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005193, ENSP000003614234I2D: score=2 STRING: ENSP00000361423
    HOXA2O433643I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0018345protein palmitoylation IDA--

    Find genes that share ontologies with ZDHHC16           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC16 (ZDH16)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZDHHC16 gene (7 alternative transcripts): 
    NM_001287803.1  NM_001287804.1  NM_032327.3  NM_198043.2  NM_198044.2  NM_198045.2  NM_198046.2  

    Unigene Cluster for ZDHHC16:

    Zinc finger, DHHC-type containing 16
    Hs.76662  [show with all ESTs]
    Unigene Representative Sequence: AB209272
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370854(uc001knk.3 uc001knl.3 uc001knm.3 uc001knn.3)
    ENST00000414567 ENST00000459777 ENST00000466895 ENST00000370846 ENST00000352634
    ENST00000353979 ENST00000370842 ENST00000345745 ENST00000462924 ENST00000433086
    ENST00000492610 ENST00000495735 ENST00000420089 ENST00000417044 ENST00000487315
    ENST00000492733 ENST00000393760(uc001knj.3 uc010qow.2)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZDHHC16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC16 (see all 9):
    hsa-miR-22 hsa-miR-34c-5p hsa-miR-146b-3p hsa-miR-449b hsa-miR-1267 hsa-miR-449a hsa-miR-34a hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC16 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZDHHC16
    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC16
    Clone
    Products:
         
    OriGene clones in human, mouse for ZDHHC16 (see all 27)
    OriGene ORF clones in mouse, rat for ZDHHC16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): ZDHHC16 (NM_032327)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZDHHC16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC16
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZDHHC16
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC16
      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC16
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC16

    Additional mRNA sequence: 

    AB209272.1 AF258563.1 AJ294945.1 AK074427.1 AK297962.1 AY359080.1 BC004535.2 BC008074.2 
    BC011749.2 BC012830.2 BC033157.1 

    Selected DOTS entries (see all 30):

    DT.100881446  DT.100881445  DT.97791878  DT.100881450  DT.75172954  DT.415742  DT.100881443  DT.100881454 
    DT.100881444  DT.95091515  DT.121278617  DT.95188805  DT.95091506  DT.121278494  DT.121278673  DT.100718186 
    DT.100659524  DT.91662225  DT.100656837  DT.100662493  DT.100671404  DT.121278601  DT.121278602  DT.95091488 

    Selected AceView cDNA sequences (see all 312):

    AI039642 AA532521 AW510416 BE272520 BX417220 CB129739 AI276289 T64516 
    AI873732 BC012830 NM_198046 AJ294945 AI190823 BX353685 CA438710 CR593129 
    AA649006 CR600260 AW439781 CB528852 AA775791 AA337175 BG000993 NM_032327 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC16 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b ·
    SP1:                                -     -                                         -                                         -                                 
    SP2:                          -     -     -                                         -                                         -                                 
    SP3:                          -     -     -                                         -                             -           -                                 
    SP4:                          -     -     -                                         -     -     -     -                       -                                 
    SP5:                          -     -     -                 -     -                 -                             -           -                                 

    ExUns: 14c
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ZDHHC16

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZDHHC16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCTTAAGG
    ZDHHC16 Expression
    About this image

    ZDHHC16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.76662
        Custom PCR Arrays for ZDHHC16
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZDHHC16
    OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC16
    QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC16
    QuantiFast Probe-based Assays in human, mouse, rat ZDHHC16
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ZDHHC16 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc161 , 5 zinc finger, DHHC domain containing 161, 5 92.06(n)1
    99.17(a)1
      19 (35.48 cM)5
    741681  NM_023740.21  NP_076229.21 
     419334725 
    chicken
    (Gallus gallus)
    Aves ZDHHC161 zinc finger, DHHC-type containing 16 75.89(n)
    73.78(a)
      423843  XM_421711.4  XP_421711.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC166
    zinc finger, DHHC-type containing 16
    67(a)
    1 ↔ 1
    GL343810.1(68857-83044)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.190942 Transcribed sequence with moderate similarity to protein more 75.22(n)    BX773791.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc639342 hypothetical protein MGC63934 77.11(n)   393316  BC053155.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG58801 CG5880 52.09(n)
    46.79(a)
      43268  NM_143282.3  NP_651539.3 
    worm
    (Caenorhabditis elegans)
    Secernentea C43H6.71 C43H6.7 42.41(n)
    33.8(a)
      183426  NM_076034.4  NP_508435.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFA36
    Palmitoyltransferase for Vac8p, required for vacuo...
    18(a)
    1 → many
    XIV(27337-28347) YNL326C


    ENSEMBL Gene Tree for ZDHHC16 (if available)
    TreeFam Gene Tree for ZDHHC16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZDHHC16 gene
    ZDHHC212  ZDHHC32  ZDHHC72  ZDHHC202  ZDHHC62  ZDHHC22  ZDHHC152  

    Find genes that share paralogs with ZDHHC16           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZDHHC16 (see all 213)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1133081281,2
    F--99207799(+) ACTTTG/CTTCAC 5 -- int11Minor allele frequency- C:0.50CSA 2
    rs1901695971,2
    --99208233(+) AGCTGA/GGCATG 5 -- int10--------
    rs1827225371,2
    --99208317(+) AAGACC/TAGCCT 5 -- int10--------
    rs1440785921,2
    C--99208335(+) ATTGCA/GAAACC 5 -- int10--------
    rs1866257371,2
    --99208352(+) CTACTA/TAAAAT 5 -- int10--------
    rs1465231071,2
    --99208386(+) GCAGGC/TGCCTG 5 -- int10--------
    rs79239131,2
    C,F,A--99208463(+) tgagcC/Tgagat 5 -- int13Minor allele frequency- T:0.50NA CSA 6
    rs1401073601,2
    C--99208484(+) ACTAC-/ATAGCCT 5 -- int10--------
    rs30660271,2
    C--99208485(+) CTACA-/AT/TA 
            
    GCCTG
    5 -- int10--------
    rs728339701,2
    C,F--99208506(+) CGAGAG/CTTCAT 5 -- int13Minor allele frequency- C:0.50WA NA CSA 6

    HapMap Linkage Disequilibrium report for ZDHHC16 (99205927 - 99217127 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZDHHC16: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZDHHC16
    DNA2.0 Custom Variant and Variant Library Synthesis for ZDHHC16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with ZDHHC16           About GenesLikeMe

    Genetic Association Database (GAD): ZDHHC16
    Human Genome Epidemiology (HuGE) Navigator: ZDHHC16 (1 document)

    Export disorders for ZDHHC16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZDHHC16 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with ZDHHC16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity. (PubMed id 12021275)1, 3, 9 Li B....Goff S.P. (J. Biol. Chem. 2002)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1. (PubMed id 17123647)1 Zhang F....Gu J. (Biochim. Biophys. Acta 2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 84287 HGNC: 20714 AceView: ZDHHC16 Ensembl:ENSG00000171307 euGenes: HUgn84287
    ECgene: ZDHHC16 H-InvDB: ZDHHC16

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZDHHC16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZDHHC16 gene:
    Search GeneIP for patents involving ZDHHC16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZDHHC16  
     OriGene qPCR primer pairs and template standards for ZDHHC16   OriGene Protein Over-expression Lysate for ZDHHC16  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZDHHC16  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZDHHC16   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZDHHC16   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZDHHC16   OriGene Custom Protein Services for ZDHHC16  

     
     
     Block miRNA regulation of human, mouse, rat ZDHHC16 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZDHHC16
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC16 Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC16
     QuantiFast Probe-based Assays in human, mouse, rat ZDHHC16 QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC16
     Custom PCR Arrays for ZDHHC16 Search Chromatin IP Primers for ZDHHC16
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZDHHC16  GeneGlobe Interaction Network for ZDHHC16
     Regulatory tfbs in ZDHHC16 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZDHHC16 GenScript cDNA clones with any tag delivered in your preferred vector for ZDHHC16
     GenScript Custom Assay Services for ZDHHC16 GenScript Custom overexpressing Cell Line Services for ZDHHC16
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZDHHC16 (ZDH16)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for ZDHHC16
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZDHHC16 antibodies
     ZDHHC16 lysates
     Antibodies for ZDHHC16
     See all of Abcam's Antibodies, Kits and Proteins for ZDHHC16
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZDHHC16
     Antibodies for ZDHHC16
     ELISAs for ZDHHC16
     CLIAs for ZDHHC16



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZDHHC16
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDHHC16
     SwitchGear 3'UTR luciferase reporter plasmids for ZDHHC16
     SwitchGear Promoter luciferase reporter plasmids for ZDHHC16
     Search ThermoFisher Antibodies for ZDHHC16
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZDHHC16
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC16
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZDHHC16
     LSBio Antibodies in human, mouse, rat for ZDHHC16
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZDHHC16
      Search eBioscience for proteins for ZDHHC16
      Search eBioscience for elisas for ZDHHC16
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZDHHC16 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4