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ZDHHC15 Gene

protein-coding   GIFtS: 48
GCID: GC0XM074588

Zinc Finger, DHHC-Type Containing 15

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, DHHC-Type Containing 151 2     Palmitoyltransferase ZDHHC152
Zinc Finger DHHC Domain-Containing Protein 152 3     Zinc Finger, DHHC Domain Containing 152
DHHC-152 3     EC 2.3.1.2253
MRX912 5     EC 2.3.18

External Ids:    HGNC: 203421   Entrez Gene: 1588662   Ensembl: ENSG000001023837   OMIM: 3005765   UniProtKB: Q96MV83   

Export aliases for ZDHHC15 gene to outside databases

Previous GC identifers: GC0XM071766 GC0XM072806 GC0XM073458 GC0XM073459 GC0XM074375 GC0XM074504 GC0XM068222


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZDHHC15 Gene:
The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are
associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Sep 2009)

GeneCards Summary for ZDHHC15 Gene:
ZDHHC15 (zinc finger, DHHC-type containing 15) is a protein-coding gene. Diseases associated with ZDHHC15 include neuronal ceroid lipofuscinosis, and mental retardation, x-linked. GO annotations related to this gene include palmitoyltransferase activity. An important paralog of this gene is ZDHHC21.

UniProtKB/Swiss-Prot: ZDH15_HUMAN, Q96MV8
Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC15 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC15 promoter sequence
   Search Chromatin IP Primers for ZDHHC15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.3   Ensembl cytogenetic band:  Xq13.3   HGNC cytogenetic band: Xq13.3

ZDHHC15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC15 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM074588:  view genomic region     (about GC identifiers)

Start:
74,588,262 bp from pter      End:
74,743,337 bp from pter
Size:
155,076 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZDH15_HUMAN, Q96MV8 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC15  
Size: 337 amino acids; 39331 Da
Secondary accessions: B3KVG7 Q3SY30 Q6UWH3
Alternative splicing: 3 isoforms:  Q96MV8-1   Q96MV8-2   Q96MV8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZDHHC15: NX_Q96MV8

Explore proteomics data for ZDHHC15 at MOPED

Post-translational modifications: 

  • Autopalmitoylated (By similarity)1
  • Modification sites at neXtProt
  • Selected DME Specific Peptides for ZDHHC15 (Q96MV8) (see all 6)
     MDHHCPW  WVNNCIG  KFHVLFL  KPDRCHHCS 


    See ZDHHC15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001139728.1  NP_001139729.1  NP_659406.1  

    ENSEMBL proteins: 
     ENSP00000362465   ENSP00000445420   ENSP00000362459  

    ZDHHC15 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZDHHC: Zinc fingers, DHHC-type

    1 InterPro protein domain:
     IPR001594 Znf_DHHC_palmitoyltrfase

    Graphical View of Domain Structure for InterPro Entry Q96MV8

    ProtoNet protein and cluster: Q96MV8

    1 Blocks protein domain: IPB001594 Zn-finger

    UniProtKB/Swiss-Prot: ZDH15_HUMAN, Q96MV8
    Domain: The DHHC domain is required for palmitoyltransferase activity
    Similarity: Belongs to the DHHC palmitoyltransferase family
    Similarity: Contains 1 DHHC-type zinc finger


    ZDHHC15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDH15_HUMAN, Q96MV8
    Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity)
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0008270zinc ion binding IEA--
    GO:0016409palmitoyltransferase activity IDA--
    GO:0016746transferase activity, transferring acyl groups ----
    GO:0019706protein-cysteine S-palmitoyltransferase activity IEA--
         
    ZDHHC15 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZDHHC15:
     Decreased POU5F1-GFP protein e 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Zdhhc15):
     embryogenesis  growth/size/body  nervous system 

    ZDHHC15 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC15
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    miRNA
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    miRTarBase miRNAs that target ZDHHC15:
    hsa-mir-335-5p (MIRT017787), hsa-mir-148b-3p (MIRT019337)

    Block miRNA regulation of human, mouse, rat ZDHHC15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC15 (see all 46):
    hsa-miR-323-3p hsa-miR-3938 hsa-miR-136 hsa-miR-562 hsa-miR-3607-3p hsa-miR-29a hsa-miR-218 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC15 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZDHHC15

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZDH15_HUMAN, Q96MV8: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    cytosol1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IDA16647879
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    ZDHHC15 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC15
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC15

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for ZDHHC15 (Q96MV83 ENSP000003624654) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    H3F3AP842433I2D: score=1 
    H3F3BP842433I2D: score=1 
    SHQ1Q6PI263I2D: score=5 
    HSP90AA1P079003I2D: score=2 
    DLG4P783523I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development ----
    GO:0016188synaptic vesicle maturation IEA--
    GO:0018345protein palmitoylation IDA--
    GO:0045184establishment of protein localization IEA--

    ZDHHC15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC15 (ZDH15)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZDHHC15 gene (3 alternative transcripts): 
    NM_001146256.1  NM_001146257.1  NM_144969.2  

    Unigene Cluster for ZDHHC15:

    Zinc finger, DHHC-type containing 15
    Hs.253211  [show with all ESTs]
    Unigene Representative Sequence: NM_144969
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373367 ENST00000482827 ENST00000541184(uc004ecg.3 uc004ech.3 uc011mqo.1 uc004eci.2)
    ENST00000373361
    miRNA
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    Block miRNA regulation of human, mouse, rat ZDHHC15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZDHHC15 (see all 46):
    hsa-miR-323-3p hsa-miR-3938 hsa-miR-136 hsa-miR-562 hsa-miR-3607-3p hsa-miR-29a hsa-miR-218 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC15 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC15
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC15

    Additional mRNA sequence: 

    AK056374.1 AK122885.1 AK123754.1 AK128587.1 AY358786.1 BC103980.1 BC103981.1 BC103982.1 

    4 DOTS entries:

    DT.102839780  DT.40261152  DT.75109446  DT.121323721 

    Selected AceView cDNA sequences (see all 32):

    AY358786 AL134778 BX955930 BU102099 AK128587 AK056374 BX280612 BQ028106 
    AI469998 NM_144969 CD637240 CD637244 CD637238 N63207 CD637242 CD637246 
    AA424051 BX441758 AI628380 AA421824 AK123754 AK122885 AI362114 AW104616 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZDHHC15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZDHHC15 Expression
    About this image

    ZDHHC15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.253211

    UniProtKB/Swiss-Prot: ZDH15_HUMAN, Q96MV8
    Tissue specificity: Expressed in placenta, liver, lung, kidney, heart and brain

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZDHHC15 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc151 , 5 zinc finger, DHHC domain containing 151, 5 93.77(n)1
    97.92(a)1
      X (46.69 cM)5
    1086721  NM_175358.41  NP_780567.11 
     1045369695 
    chicken
    (Gallus gallus)
    Aves ZDHHC151 zinc finger, DHHC-type containing 15 74.92(n)
    75.23(a)
      422329  XM_420303.3  XP_420303.2 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC156
    zinc finger, DHHC-type containing 15
    68(a)
    1 ↔ 1
    GL343825.1(104184-113883)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia zdhhc151 zinc finger, DHHC-type containing 15 69.25(n)
    68.66(a)
      100488081  XM_002931791.2  XP_002931837.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc02b122 Transcribed sequence with weak similarity to protein more 76.08(n)    CK026759.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG172876
    CG14076
    --
    33(a)
    33(a)
    many ↔ many
    many ↔ many
    2R(13044039-13045821)
    2R(5915948-5920393)
    worm
    (Caenorhabditis elegans)
    Secernentea dhhc-46
    spe-106
    Protein SPE-10 (spe-10) mRNA, complete cds
    30(a)
    29(a)
    many ↔ many
    many ↔ many
    III(9863252-9867786) WBGene00014075
    V(10384157-10385711) WBGene00004964
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFA3(YNL326C)4 Palmitoyltransferase for Vac8p, required for vacuolar more   --   14(28347-27337) 855390  NP_014073.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G608001 AT3G60800 49.65(n)
    40.08(a)
      825251  NM_115944.3  NP_191639.2 
    rice
    (Oryza sativa)
    Liliopsida Os03g08043001 Os03g0804300 48.9(n)
    36.36(a)
      4334485  NM_001058153.1  NP_001051618.1 


    ENSEMBL Gene Tree for ZDHHC15 (if available)
    TreeFam Gene Tree for ZDHHC15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZDHHC15 gene
    ZDHHC212  ZDHHC32  ZDHHC72  ZDHHC202  ZDHHC162  ZDHHC62  ZDHHC22  
    2 SIMAP similar genes for ZDHHC15 using alignment to 2 protein entries:     ZDH15_HUMAN (see all proteins):
    ZDHHC2    ZDHHC20

    ZDHHC15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZDHHC15 (see all 2386)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1135982821,2
    C,F--74587832(+) CATAGT/CCTTCA 2 -- ds50011Minor allele frequency- C:0.00CSA 1
    rs1463839961,2
    --74587835(+) AGCCTG/TCAGTG 2 -- ds50010--------
    rs1807435091,2
    --74587865(+) GTTCAC/TTTCAC 2 -- ds50010--------
    rs59027381,2
    C--74588247(+) TTAGG-/AAAAAA 2 -- ds50010--------
    rs1397174511,2
    --74588330(+) TTCTGA/CACCAA 2 -- ut310--------
    rs120149951,2
    C,H--74588788(+) ATACCC/TGCATG 2 -- ut31 ese30--------
    rs70523141,2
    C,F,A,H--74589117(+) TCCTGC/TTGAAG 2 -- ut31 ese318Minor allele frequency- T:0.39NS EA NA CSA 1985
    rs1861265971,2
    C--74589118(+) CCTGCC/TGAAGA 2 -- ut310--------
    rs722150311,2
    C--74589151(+) GTGTA-/TGTGTG
            
    TGTGT
    2 -- cds10--------
    rs723477201,2
    C--74589151(+) GTGTA-/TGTG  
            
    TGTGT
    2 -- ut310--------

    HapMap Linkage Disequilibrium report for ZDHHC15 (74588262 - 74743337 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ZDHHC15:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2740234CNV Deletion23290073
    esv988916CNV Deletion20482838
    esv2740237CNV Deletion23290073
    esv2740236CNV Deletion23290073
    esv1585432CNV Deletion17803354
    esv2740235CNV Deletion23290073
    nsv425323CNV Loss16902084
    esv25282CNV Gain19812545

    Human Gene Mutation Database (HGMD): ZDHHC15
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZDHHC15
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300576   
    OMIM disorders: 300577  
    UniProtKB/Swiss-Prot: ZDH15_HUMAN, Q96MV8
  • Mental retardation, X-linked 91 (MRX91) [MIM:300577]: A disorder characterized by significantly below
    average general intellectual functioning associated with impairments in adaptive behavior and manifested during
    the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental
    retardation, while syndromic mental retardation presents with associated physical, neurological and/or
    psychiatric manifestations. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 6 diseases for ZDHHC15:    
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    neuronal ceroid lipofuscinosis    mental retardation, x-linked    mental retardation    neuronitis
    multiple myeloma    myeloma


    ZDHHC15 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZDHHC15

    Export disorders for ZDHHC15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZDHHC15 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZDHHC15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    2. Loss of ZDHHC15 expression in a woman with a balanced translocation t(X;15)(q13.3;cen) and severe mental retardation. (PubMed id 15915161)1, 2 Mansouri M.R.... Dahl N. (Eur. J. Hum. Genet. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. (PubMed id 16647879)1 Ohno Y....Igarashi Y. (Biochim. Biophys. Acta 2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 158866 HGNC: 20342 AceView: ZDHHC15 Ensembl:ENSG00000102383 euGenes: HUgn158866
    ECgene: ZDHHC15 H-InvDB: ZDHHC15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZDHHC15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZDHHC15 gene:
    Search GeneIP for patents involving ZDHHC15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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