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ZDHHC13 Gene

protein-coding   GIFtS: 53
GCID: GC11P019095

Zinc Finger, DHHC-Type Containing 13

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger, DHHC-Type Containing 131 2     HIP3RP2 3
HIP14L2 3 5     HIP14-Related Protein2 3
Huntingtin-Interacting Protein 14-Related Protein2 3     Huntingtin Interacting Protein HIP3RP2
Huntingtin-Interacting Protein HIP3RP2 3     Palmitoyltransferase ZDHHC132
Putative MAPK-Activating Protein PM032 3     Probable Palmitoyltransferase ZDHHC132
Putative NF-Kappa-B-Activating Protein 2092 3     Zinc Finger, DHHC Domain Containing 132
Zinc Finger DHHC Domain-Containing Protein 132 3     EC 2.3.1.2253
DHHC-132 3     EC 2.3.18

External Ids:    HGNC: 184131   Entrez Gene: 545032   Ensembl: ENSG000001770547   OMIM: 6128155   UniProtKB: Q8IUH43   
ORGUL members:         

Export aliases for ZDHHC13 gene to outside databases

Previous GC identifers: GC11P019104 GC11P018822


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZDHHC13 Gene:
ZDHHC13 (zinc finger, DHHC-type containing 13) is a protein-coding gene. GO annotations related to this gene include palmitoyltransferase activity and signal transducer activity. An important paralog of this gene is ZDHHC12.

UniProtKB/Swiss-Prot: ZDH13_HUMAN, Q8IUH4
Function: Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZDHHC13 gene promoter:
         TBP   MEF-2   NCX/Ncx   NF-kappaB   HEN1   MEF-2A   NF-kappaB2   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZDHHC13 promoter sequence
   Search Chromatin IP Primers for ZDHHC13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZDHHC13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.1   Ensembl cytogenetic band:  11p15.1   HGNC cytogenetic band: 11p15.1

ZDHHC13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZDHHC13 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P019095:  view genomic region     (about GC identifiers)

Start:
19,138,646 bp from pter      End:
19,197,969 bp from pter
Size:
59,324 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZDH13_HUMAN, Q8IUH4 (See protein sequence)
Recommended Name: Palmitoyltransferase ZDHHC13  
Size: 622 amino acids; 70861 Da
Sequence caution: Sequence=BAA91856.1; Type=Erroneous termination; Positions=482; Note=Translated as Cys;
Secondary accessions: Q7Z2D3 Q86VK2 Q9NV30 Q9NV99
Alternative splicing: 3 isoforms:  Q8IUH4-1   Q8IUH4-2   Q8IUH4-3   

Explore the universe of human proteins at neXtProt for ZDHHC13: NX_Q8IUH4

Explore proteomics data for ZDHHC13 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys80
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ZDHHC13 (Q8IUH4) (see all 15)
     LHWAAIN  WIIYGSF  KCELFLLL  LAETGSLD 


    See ZDHHC13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001001483.1  NP_061901.2  

    ENSEMBL proteins: 
     ENSP00000400113   ENSP00000382288  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing
    ZDHHC: Zinc fingers, DHHC-type

    3 InterPro protein domains:
     IPR001594 Znf_DHHC_palmitoyltrfase
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q8IUH4

    ProtoNet protein and cluster: Q8IUH4

    2 Blocks protein domains:
    IPB001594 Zn-finger
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ZDH13_HUMAN, Q8IUH4
    Domain: The DHHC domain is required for palmitoyltransferase activity (By similarity)
    Similarity: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 1 DHHC-type zinc finger


    Find genes that share domains with ZDHHC13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZDH13_HUMAN, Q8IUH4
    Function: Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport (By similarity)
    Catalytic activity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

         Enzyme Numbers (IUBMB): EC 2.3.1.2251 EC 2.3.12

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0015095magnesium ion transmembrane transporter activity ISS--
    GO:0016409palmitoyltransferase activity ISS--
         
    Find genes that share ontologies with ZDHHC13           About GenesLikeMe


    Phenotypes:
         Selected MGI mutant phenotypes (inferred from 2 alleles(MGI details for Zdhhc13) (see all 16):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  growth/size/body 
     hematopoietic system  homeostasis/metabolism  immune system  integument  liver/biliary system 
     mortality/aging  muscle  nervous system  other  renal/urinary system 

    Find genes that share phenotypes with ZDHHC13           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZDHHC13
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZDHHC13
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    hsa-miR-548p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC13 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZDH13_HUMAN, Q8IUH4: Golgi apparatus membrane; Multi-pass membrane protein (By similarity). Cytoplasmic vesicle
    membrane; Multi-pass membrane protein (By similarity). Note=Low extracellular Mg(2+) induces increase in Golgi
    and in post-Golgi vesicles (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    plasma membrane3
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane ISS--
    GO:0005783endoplasmic reticulum IDA16647879
    GO:0005794Golgi apparatus IDA--
    GO:0016021integral component of membrane IEA--
    GO:0030660Golgi-associated vesicle membrane ISS--

    Find genes that share ontologies with ZDHHC13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZDHHC13
    Interactions:

        Search GeneGlobe Interaction Network for ZDHHC13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZDHHC13 (Q8IUH43 ENSP000004001134) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCBD1P614573I2D: score=1 
    RELAQ042063I2D: score=1 
    ARFGAP1ENSP000003146154STRING: ENSP00000314615
    SIN3AENSP000003536224STRING: ENSP00000353622
    VTI1AENSP000003767924STRING: ENSP00000376792
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IMP12761501
    GO:0008152metabolic process ISS--
    GO:0015693magnesium ion transport ----
    GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling IMP12761501

    Find genes that share ontologies with ZDHHC13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZDHHC13 (ZDH13)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZDHHC13 gene (2 alternative transcripts): 
    NM_001001483.2  NM_019028.2  

    Unigene Cluster for ZDHHC13:

    Zinc finger, DHHC-type containing 13
    Hs.188569  [show with all ESTs]
    Unigene Representative Sequence: BC036020
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532026 ENST00000446113(uc001mpi.3) ENST00000399351(uc001mpj.3)
    ENST00000525490 ENST00000524744 ENST00000532812 ENST00000530698 ENST00000530100

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate ZDHHC13:
    hsa-miR-548p
    SwitchGear 3'UTR luciferase reporter plasmidZDHHC13 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ZDHHC13
      QuantiFast Probe-based Assays in human, mouse, rat ZDHHC13

    Additional mRNA sequence: 

    AB024495.1 AB097014.1 AB097027.1 AK001714.1 AK001803.1 AK001831.1 AK123539.1 AK291348.1 
    AL833714.1 BC036020.1 BC050690.1 BC056152.1 

    11 DOTS entries:

    DT.409720  DT.100644836  DT.100009358  DT.101982446  DT.405934  DT.91854224  DT.97842391  DT.100748871 
    DT.95209254  DT.95260580  DT.205292 

    Selected AceView cDNA sequences (see all 91):

    BM823922 AK001831 BQ082829 AL833714 BM849174 BQ227824 BP342756 AB097027 
    AI092244 AI754385 BC056152 BM825680 AB097014 BC050690 BM904379 NM_001001483 
    CD672653 BM769058 AA459681 AW438768 BM823648 AA811609 AU134968 BM052998 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC13    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17
    SP1:                                                                          -                                       
    SP2:        -                                                                 -                                       
    SP3:                                                                          -                                       
    SP4:                                                                                                                  


    ECgene alternative splicing isoforms for ZDHHC13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZDHHC13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTTTCACC
    ZDHHC13 Expression
    About this image


    ZDHHC13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    ZDHHC13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZDHHC13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.188569
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ZDHHC13 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zdhhc131 , 5 zinc finger, DHHC domain containing 131, 5 89.92(n)1
    91.16(a)1
      7 (31.11 cM)5
    2439831  NM_028031.31  NP_082307.11 
     487890035 
    chicken
    (Gallus gallus)
    Aves ZDHHC131 zinc finger, DHHC-type containing 13 68.74(n)
    65.47(a)
      422980  NM_001031171.1  NP_001026342.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZDHHC136
    zinc finger, DHHC-type containing 13
    64(a)
    1 ↔ 1
    1(56061669-56108840)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004931451 palmitoyltransferase ZDHHC13-like 62.48(n)
    61.26(a)
      100493145  XM_002942834.2  XP_002942880.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi22e092 wufi22e09 71.03(n)   333946  CK015990.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hip146
    Huntingtin-interacting protein 14
    35(a)
    1 → many
    3L(15981336-15985564)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes AKR16
    AKR26
    Palmitoyl transferase involved in protein palmitoy...
    Ankyrin repeat-containing protein similar to Akr1p...
    20(a)
    19(a)
    many ↔ many
    many ↔ many
    IV(996029-998323) YDR264C
    XV(394837-397086) YOR034C


    ENSEMBL Gene Tree for ZDHHC13 (if available)
    TreeFam Gene Tree for ZDHHC13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZDHHC13 gene
    ZDHHC122  ZDHHC172  
    1 SIMAP similar gene for ZDHHC13 using alignment to 1 protein entry:     ZDH13_HUMAN:
    ZDHHC17

    Find genes that share paralogs with ZDHHC13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZDHHC13 (see all 1307)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1144474011,2
    C,F--19136695(+) AGTGCA/GGACGC 2 -- us2k11Minor allele frequency- G:0.08WA 118
    rs110250171,2
    C,F--19136734(+) GTTCAG/ACATCT 2 -- us2k110Minor allele frequency- A:0.29NA WA EA 508
    rs758464401,2
    C,F--19136736(+) TCAGCG/ATCTTC 2 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1813437881,2
    --19136745(+) TCTAAA/TTCAGA 2 -- us2k10--------
    rs1143184051,2
    C,F--19136887(+) TCCTCC/TCAGGA 2 -- us2k11Minor allele frequency- T:0.03WA 118
    rs110250181,2
    C,F,A,H--19136906(+) AAATAC/ACACCC 2 -- us2k119Minor allele frequency- A:0.27NS EA NA WA 2336
    rs110250191,2
    C,A,H--19137174(+) ttttgG/Tatttt 2 -- us2k10--------
    rs125740761,2
    C,F,H--19137185(+) TAGTAG/AAAACG 2 -- us2k12Minor allele frequency- A:0.33NA 6
    rs1850935721,2
    C--19137251(+) GCCTCA/GGCCTC 2 -- us2k10--------
    rs125751851,2
    H--19137385(+) ACTTGT/GCGGAA 2 -- us2k14Minor allele frequency- G:0.00NS EA 420

    HapMap Linkage Disequilibrium report for ZDHHC13 (19138646 - 19197969 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZDHHC13:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662583CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZDHHC13
    DNA2.0 Custom Variant and Variant Library Synthesis for ZDHHC13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612815    OMIM disorders: --


    Find genes that share disorders with ZDHHC13           About GenesLikeMe

    Genetic Association Database (GAD): ZDHHC13

    Export disorders for ZDHHC13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZDHHC13 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ZDHHC13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport. (PubMed id 18794299)1, 3, 9 Goytain A.... Quamme G.A. (J. Biol. Chem. 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (Oncogene 2003)
    5. HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis. (PubMed id 12393793)1, 2 Singaraja R.R....Hayden M.R. (Hum. Mol. Genet. 2002)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54503 HGNC: 18413 AceView: ZDHHC13 Ensembl:ENSG00000177054 euGenes: HUgn54503
    ECgene: ZDHHC13 H-InvDB: ZDHHC13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZDHHC13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZDHHC13 gene:
    Search GeneIP for patents involving ZDHHC13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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