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Aliases for ZDHHC11B Gene

Aliases for ZDHHC11B Gene

  • Zinc Finger, DHHC-Type Containing 11B 2 3
  • Zinc Finger DHHC Domain-Containing Protein 11B 3 4
  • DHHC-11B 3 4
  • Probable Palmitoyltransferase ZDHHC11B 3
  • EC 2.3.1.225 4

External Ids for ZDHHC11B Gene

Previous GeneCards Identifiers for ZDHHC11B Gene

  • GC05M000769

Summaries for ZDHHC11B Gene

GeneCards Summary for ZDHHC11B Gene

ZDHHC11B (Zinc Finger, DHHC-Type Containing 11B) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups. An important paralog of this gene is ZDHHC4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZDHHC11B Gene

Genomics for ZDHHC11B Gene

Regulatory Elements for ZDHHC11B Gene

Genomic Location for ZDHHC11B Gene

Start:
710,355 bp from pter
End:
784,742 bp from pter
Size:
74,388 bases
Orientation:
Minus strand

Genomic View for ZDHHC11B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZDHHC11B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZDHHC11B Gene

Proteins for ZDHHC11B Gene

  • Protein details for ZDHHC11B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7U3-ZH11B_HUMAN
    Recommended name:
    Probable palmitoyltransferase ZDHHC11B
    Protein Accession:
    P0C7U3
    Secondary Accessions:
    • A6NHR3

    Protein attributes for ZDHHC11B Gene

    Size:
    371 amino acids
    Molecular mass:
    41895 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZDHHC11B Gene

Proteomics data for ZDHHC11B Gene at MOPED

Post-translational modifications for ZDHHC11B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZDHHC11B Gene

No data available for DME Specific Peptides for ZDHHC11B Gene

Domains for ZDHHC11B Gene

Gene Families for ZDHHC11B Gene

HGNC:
  • ZDHHC :Zinc fingers, DHHC-type

Protein Domains for ZDHHC11B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZDHHC11B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7U3

UniProtKB/Swiss-Prot:

ZH11B_HUMAN :
  • P0C7U3
Domain:
  • The DHHC domain is required for palmitoyltransferase activity.
Family:
  • Belongs to the DHHC palmitoyltransferase family.
Similarity:
  • Contains 1 DHHC-type zinc finger.
genes like me logo Genes that share domains with ZDHHC11B: view

Function for ZDHHC11B Gene

Molecular function for ZDHHC11B Gene

UniProtKB/Swiss-Prot CatalyticActivity: Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA

Enzyme Numbers (IUBMB) for ZDHHC11B Gene

Gene Ontology (GO) - Molecular Function for ZDHHC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0019706 protein-cysteine S-palmitoyltransferase activity IEA --
genes like me logo Genes that share ontologies with ZDHHC11B: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZDHHC11B

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZDHHC11B Gene

Localization for ZDHHC11B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZDHHC11B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZDHHC11B Gene COMPARTMENTS Subcellular localization image for ZDHHC11B gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for ZDHHC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ZDHHC11B: view

Pathways for ZDHHC11B Gene

SuperPathways for ZDHHC11B Gene

No Data Available

Interacting Proteins for ZDHHC11B Gene

Gene Ontology (GO) - Biological Process for ZDHHC11B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ZDHHC11B: view

No data available for Pathways by source for ZDHHC11B Gene

Transcripts for ZDHHC11B Gene

mRNA/cDNA for ZDHHC11B Gene

(17) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZDHHC11B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZDHHC11B Gene

No ASD Table

Relevant External Links for ZDHHC11B Gene

GeneLoc Exon Structure for
ZDHHC11B
ECgene alternative splicing isoforms for
ZDHHC11B

Expression for ZDHHC11B Gene

mRNA expression in normal human tissues for ZDHHC11B Gene

mRNA differential expression in normal tissues according to GTEx for ZDHHC11B Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (4.6) and Brain - Cerebellum (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZDHHC11B Gene

genes like me logo Genes that share expressions with ZDHHC11B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZDHHC11B Gene

Orthologs for ZDHHC11B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZDHHC11B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 95 (a)
OneToMany
ZDHHC11B 35
  • 96.51 (n)
  • 95.18 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 44 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zdhhc11 16
Zdhhc11 36
  • 52 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 53 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CU694320.1 36
  • 32 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG17075 36
  • 11 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea dhhc-11 36
  • 20 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ERF2 36
  • 15 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10560 36
  • 26 (a)
OneToMany
Species with no ortholog for ZDHHC11B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZDHHC11B Gene

ENSEMBL:
Gene Tree for ZDHHC11B (if available)
TreeFam:
Gene Tree for ZDHHC11B (if available)

Paralogs for ZDHHC11B Gene

Paralogs for ZDHHC11B Gene

Selected SIMAP similar genes for ZDHHC11B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZDHHC11B: view

Variants for ZDHHC11B Gene

Sequence variations from dbSNP and Humsavar for ZDHHC11B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs172870 -- 745,191(-) AAGGA(G/T)TTCTC missense, reference
rs325135 -- 745,259(-) TAATA(A/C)CCGCA missense, reference
rs325138 -- 753,013(+) CAGGG(A/C)CATTC intron-variant
rs364673 -- 741,973(-) atcaa(A/C)aagac intron-variant
rs365283 -- 713,916(+) TTGTA(C/T)CTCCT intron-variant

Relevant External Links for ZDHHC11B Gene

HapMap Linkage Disequilibrium report
ZDHHC11B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZDHHC11B Gene

Disorders for ZDHHC11B Gene

No disorders were found for ZDHHC11B Gene.

No data available for UniProtKB/Swiss-Prot for ZDHHC11B Gene

Publications for ZDHHC11B Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4

Products for ZDHHC11B Gene

Sources for ZDHHC11B Gene

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