ZDBF2 Gene
protein-coding GIFtS: 37
GCID: GC02P207139
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zinc finger, DBF-type containing 2
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Aliases
for ZDBF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, DBF-Type Containing 21 2 | | KIAA15711 3 | | FLJ453381 | | DBF4-Type Zinc Finger-Containing Protein 22 |
Export aliases for ZDBF2 gene to outside databasesPrevious GC identifers: GC02P206848 GC02P198990 |
Summaries
for ZDBF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZDBF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZDBF2 gene promoter:
SRF Sox5 USF1 p300 Brachyury SRF (504 AA) IRF-1 Evi-1 USF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZDBF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZDBF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q33.3 Ensembl cytogenetic band: 2q33.3 HGNC cytogenetic band: 2q33.3ZDBF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P207139: view genomic region
(about GC identifiers)
Start:
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207,139,387 bp from pter |
End:
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207,179,148 bp from pter |
Size:
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39,762 bases |
Orientation:
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plus strand |
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Proteins
for ZDBF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZDBF2_HUMAN, Q9HCK1 (See
protein sequence)Recommended Name: DBF4-type zinc finger-containing protein 2 Size: 2354 amino acids; 265618 Da
Sequence caution: Sequence=BAC85454.1; Type=Erroneous initiation;
Secondary accessions: Q6ZNP7 Q6ZSN8Explore the universe of human proteins at neXtProt for ZDBF2: NX_Q9HCK1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HCK1
ZDBF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065974.1
ENSEMBL proteins: ENSP00000363545
Human Recombinant Protein Products for ZDBF2:
ZDBF2 Antibody Products:
Assay Products for ZDBF2: |
Protein
Domains /
Families
for ZDBF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZDBF2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9HCK1ProtoNet protein and cluster: Q9HCK1 UniProtKB/Swiss-Prot: ZDBF2_HUMAN, Q9HCK1Similarity: Contains 1 DBF4-type zinc finger |
Function
for ZDBF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZDBF2 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZDBF2 (NM_020923) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZDBF2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZDBF2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDBF2 |
|
Pathways & Interactions
for ZDBF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZDBF2
1 Interacting protein for ZDBF2 (Q9HCK13) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for ZDBF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZDBF2
Search CenterWatch for drugs/clinical trials and news about ZDBF2
|
Transcripts
for ZDBF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZDBF2 gene: NM_020923.1 Unigene Cluster for ZDBF2: Zinc finger, DBF-type containing 2 Hs.110489 [show with all ESTs]Unigene Representative Sequence: NM_0209231 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000374423(uc002vbp.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZDBF2 (NM_020923) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZDBF2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZDBF2 |
Additional cDNA sequence: AB046791.2 AK024339.1 AK127271.1 AK130893.1 2 DOTS entries: DT.206131 DT.100741554 17 AceView cDNA sequences: BX093847 AU137494 AI151388 AI128443 CB160399 AI128504 BX113617 BC028329 AK002005 T58264 AI653148 BE535795 AU157195 T54342 BE734382 T85180 T84296
GeneLoc Exon Structure
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Expression
for ZDBF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZDBF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAACTAAT
About this image
See ZDBF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZDBF2
SOURCE GeneReport for Unigene cluster: Hs.110489
SABiosciences Custom PCR Arrays for ZDBF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZDBF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZDBF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZDBF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZDBF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDBF2 |
Orthologs
for ZDBF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for ZDBF2 gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for ZDBF2 (if available)
TreeFam Gene Tree for ZDBF2 (if available) |
Paralogs
for ZDBF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZDBF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZDBF2 (207139387 - 207179148 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZDBF2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZDBF2 |
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Disorders
/ Diseases
for ZDBF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZDBF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZDBF2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZDBF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared wit h bipolar disorder. (PubMed id 22688191)1 Bergen S.E....Sullivan P.F. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Identification of the mouse paternally expressed impr inted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chrom osome 2. (PubMed id 19200453)1 Kobayashi H....Kono T. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
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External Searches for ZDBF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZDBF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZDBF2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZDBF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZDBF2 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZDBF2 gene:
Search GeneIP for patents involving ZDBF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZDBF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZDBF2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZDBF2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZDBF2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZDBF2 | | OriGene 3'-UTR Clone for ZDBF2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZDBF2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZDBF2 | | OriGene Custom Protein Services for ZDBF2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZDBF2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZDBF2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZDBF2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZDBF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZDBF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZDBF2 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZDBF2 |
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 | | | ZDBF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZDBF2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZDBF2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZDBF2 |
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