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Aliases for ZCWPW1 Gene

Aliases for ZCWPW1 Gene

  • Zinc Finger, CW Type With PWWP Domain 1 2 3
  • Zinc Finger, CW-Type With PWWP Domain 1 2 3
  • Zinc Finger CW-Type PWWP Domain Protein 1 3
  • ZCW1 3

External Ids for ZCWPW1 Gene

Summaries for ZCWPW1 Gene

GeneCards Summary for ZCWPW1 Gene

ZCWPW1 (Zinc Finger, CW Type With PWWP Domain 1) is a Protein Coding gene. An important paralog of this gene is ZCWPW2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCWPW1 Gene

Genomics for ZCWPW1 Gene

Genomic Location for ZCWPW1 Gene

Start:
100,400,826 bp from pter
End:
100,429,414 bp from pter
Size:
28,589 bases
Orientation:
Minus strand

Genomic View for ZCWPW1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZCWPW1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCWPW1 Gene

Regulatory Elements for ZCWPW1 Gene

Proteins for ZCWPW1 Gene

  • Protein details for ZCWPW1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0M4-ZCPW1_HUMAN
    Recommended name:
    Zinc finger CW-type PWWP domain protein 1
    Protein Accession:
    Q9H0M4
    Secondary Accessions:
    • A8MVF5
    • B4DUQ2
    • Q8NA98
    • Q9BUD0
    • Q9NWF7

    Protein attributes for ZCWPW1 Gene

    Size:
    648 amino acids
    Molecular mass:
    72007 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB66669.1; Type=Frameshift; Positions=487; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZCWPW1 Gene

    Alternative splice isoforms for ZCWPW1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZCWPW1 Gene

Proteomics data for ZCWPW1 Gene at MOPED

Post-translational modifications for ZCWPW1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCWPW1 Gene

No data available for DME Specific Peptides for ZCWPW1 Gene

Domains for ZCWPW1 Gene

Protein Domains for ZCWPW1 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

ZCPW1_HUMAN
Domain:
  • Contains 1 PWWP domain.:
    • Q9H0M4
Similarity:
  • Contains 1 CW-type zinc finger.:
    • Q9H0M4
genes like me logo Genes that share domains with ZCWPW1: view

No data available for Gene Families for ZCWPW1 Gene

Function for ZCWPW1 Gene

Gene Ontology (GO) - Molecular Function for ZCWPW1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZCWPW1: view

Phenotypes for ZCWPW1 Gene

GenomeRNAi human phenotypes for ZCWPW1:
genes like me logo Genes that share phenotypes with ZCWPW1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZCWPW1 Gene

Localization for ZCWPW1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZCWPW1 Gene COMPARTMENTS Subcellular localization image for ZCWPW1 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

No data available for Gene Ontology (GO) - Cellular Components for ZCWPW1 Gene

Pathways for ZCWPW1 Gene

SuperPathways for ZCWPW1 Gene

No Data Available

Interacting Proteins for ZCWPW1 Gene

Gene Ontology (GO) - Biological Process for ZCWPW1 Gene

None

No data available for Pathways by source for ZCWPW1 Gene

Transcripts for ZCWPW1 Gene

Unigene Clusters for ZCWPW1 Gene

Zinc finger, CW type with PWWP domain 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZCWPW1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1:
SP2: - -
SP3: - -
SP4: -
SP5: -

Relevant External Links for ZCWPW1 Gene

GeneLoc Exon Structure for
ZCWPW1
ECgene alternative splicing isoforms for
ZCWPW1

Expression for ZCWPW1 Gene

mRNA expression in normal human tissues for ZCWPW1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZCWPW1 Gene

This gene is overexpressed in Testis (11.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZCWPW1 Gene

SOURCE GeneReport for Unigene cluster for ZCWPW1 Gene Hs.105191

genes like me logo Genes that share expressions with ZCWPW1: view

Orthologs for ZCWPW1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZCWPW1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZCWPW1 36
  • 99.59 (n)
  • 99.23 (a)
ZCWPW1 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZCWPW1 36
  • 81.46 (n)
  • 70.19 (a)
ZCWPW1 37
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZCWPW1 36
  • 81.72 (n)
  • 71.22 (a)
ZCWPW1 37
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zcwpw1 36
  • 74.57 (n)
  • 61.22 (a)
Zcwpw1 16
Zcwpw1 37
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZCWPW1 37
  • 38 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100910636 36
  • 74.24 (n)
  • 61.44 (a)
lizard
(Anolis carolinensis)
Reptilia ZCWPW1 37
  • 53 (a)
OneToOne
Species with no ortholog for ZCWPW1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZCWPW1 Gene

ENSEMBL:
Gene Tree for ZCWPW1 (if available)
TreeFam:
Gene Tree for ZCWPW1 (if available)

Paralogs for ZCWPW1 Gene

Paralogs for ZCWPW1 Gene

genes like me logo Genes that share paralogs with ZCWPW1: view

Variants for ZCWPW1 Gene

Sequence variations from dbSNP and Humsavar for ZCWPW1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1000215 -- 100,406,920(+) ACTCC(C/T)TTCAA intron-variant
rs1000217 -- 100,407,147(+) CATGT(A/C)TCTTA intron-variant
rs1476679 -- 100,406,823(+) TGTTA(C/T)GGACT intron-variant
rs1636992 -- 100,408,043(+) cctcc(C/T)gggtt intron-variant
rs1636993 -- 100,408,171(+) gtctc(A/C)aactt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZCWPW1 Gene

Variant ID Type Subtype PubMed ID
esv2734888 CNV Deletion 23290073
nsv831071 CNV Loss 17160897
nsv819923 CNV Loss 19587683
nsv527107 CNV Loss 19592680
dgv7398n71 CNV Loss 21882294
nsv888779 CNV Loss 21882294
dgv1226e199 CNV Deletion 23128226

Relevant External Links for ZCWPW1 Gene

HapMap Linkage Disequilibrium report
ZCWPW1

Disorders for ZCWPW1 Gene

No disorders were found for ZCWPW1 Gene.

No data available for UniProtKB/Swiss-Prot for ZCWPW1 Gene

Publications for ZCWPW1 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants. (PMID: 14607086) Perry J. … Zhao Y. (Trends Biochem. Sci. 2003) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Structural insight into the zinc finger CW domain as a histone modification reader. (PMID: 20826339) He F. … Muto Y. (Structure 2010) 2 3

Products for ZCWPW1 Gene

Sources for ZCWPW1 Gene

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