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ZCCHC7 Gene

protein-coding   GIFtS: 54
GCID: GC09P037120

Zinc Finger, CCHC Domain Containing 7

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, CCHC Domain Containing 71 2
TRAMP-Like Complex RNA-Binding Factor ZCCHC72 3
AIR12
Zinc Finger CCHC Domain-Containing Protein 72

External Ids:    HGNC: 262091   Entrez Gene: 841862   Ensembl: ENSG000001479057   UniProtKB: Q8N3Z63   

Export aliases for ZCCHC7 gene to outside databases

Previous GC identifers: GC09P037111 GC09P037112 GC09P037113 GC09P037071


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZCCHC7 Gene:
ZCCHC7 (zinc finger, CCHC domain containing 7) is a protein-coding gene. GO annotations related to this gene include nucleic acid binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008413.19  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZCCHC7 gene promoter:
         Max1   SREBP-1c   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   SREBP-1b   Evi-1   POU2F1   SREBP-1a   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZCCHC7 promoter sequence
   Search Chromatin IP Primers for ZCCHC7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZCCHC7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.2   Ensembl cytogenetic band:  9p13.2   HGNC cytogenetic band: 9p13.1

ZCCHC7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZCCHC7 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P037120:  view genomic region     (about GC identifiers)

Start:
37,120,469 bp from pter      End:
37,358,146 bp from pter
Size:
237,678 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZCHC7_HUMAN, Q8N3Z6 (See protein sequence)
Recommended Name: Zinc finger CCHC domain-containing protein 7  
Size: 543 amino acids; 63052 Da
Subunit: Component of a nucleolar TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an
helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding
factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with
nuclear, or nucleolar RNA exosomes
Caution: It is uncertain whether Met-1 or Met-2 is the initiator
Sequence caution: Sequence=AAH36940.1; Type=Erroneous initiation; Sequence=BAB15418.1; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAC11087.1; Type=Erroneous
initiation; Sequence=BAG37581.1; Type=Erroneous initiation; Sequence=CAI12726.1; Type=Erroneous initiation;
Secondary accessions: B2RCI4 D3DRQ0 Q5T0Q8 Q5T0Q9 Q5T0R0 Q8N2M1 Q8N4J2 Q8TBK8 Q9H648 Q9P0F0
Alternative splicing: 2 isoforms:  Q8N3Z6-1   Q8N3Z6-2   

Explore the universe of human proteins at neXtProt for ZCCHC7: NX_Q8N3Z6

Explore proteomics data for ZCCHC7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZCCHC7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001276048.1  NP_001276049.1  NP_001276050.1  NP_115602.2  

    ENSEMBL proteins: 
     ENSP00000337839   ENSP00000316365   ENSP00000443113  

    ZCCHC7 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZCCHC7

     
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    Search eBioscience for ELISAs for ZCCHC7 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZCCHC: Zinc fingers, CCHC domain containing

    1 InterPro protein domain:
     IPR001878 Znf_CCHC

    Graphical View of Domain Structure for InterPro Entry Q8N3Z6

    ProtoNet protein and cluster: Q8N3Z6

    1 Blocks protein domain: IPB001878 C2HC-type zinc-finger signature

    UniProtKB/Swiss-Prot: ZCHC7_HUMAN, Q8N3Z6
    Similarity: Contains 4 CCHC-type zinc fingers


    Find genes that share domains with ZCCHC7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0008270zinc ion binding IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with ZCCHC7           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZCCHC7:
     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZCCHC7
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZCCHC7

    miRNA
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    miRTarBase miRNAs that target ZCCHC7:
    hsa-mir-365a-3p (MIRT044027)

    Block miRNA regulation of human, mouse, rat ZCCHC7 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZCCHC7:
    hsa-miR-1236
    SwitchGear 3'UTR luciferase reporter plasmidZCCHC7 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ZCCHC7
    Predesigned siRNA for gene silencing in human, mouse, rat ZCCHC7

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC7

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZCHC7_HUMAN, Q8N3Z6: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus4
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with ZCCHC7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZCCHC7 About    
    See pathways by source

    SuperPathContained pathways About
    1Deadenylation-dependent mRNA decay
    RNA degradation0.48


    Find genes that share SuperPaths with ZCCHC7           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for ZCCHC7):
        RNA degradation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZCCHC7
    Interactions:

        Search GeneGlobe Interaction Network for ZCCHC7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZCCHC7 (Q8N3Z62, 3 ENSP000003378394) via UniProtKB, MINT, STRING, and/or I2D (see all 154)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNIP1Q8TAD82, 3MINT-62166 I2D: score=3 
    PAPD5Q8NDF83, ENSP000003969954I2D: score=1 STRING: ENSP00000396995
    PAPD7Q5XG873, ENSP000002308594I2D: score=1 STRING: ENSP00000230859
    SREBF2Q127723I2D: score=2 
    UBE2IP632793I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZCCHC7 (ZCHC7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZCCHC7 gene (4 alternative transcripts): 
    NM_001289119.1  NM_001289120.1  NM_001289121.1  NM_032226.2  

    Unigene Cluster for ZCCHC7:

    Zinc finger, CCHC domain containing 7
    Hs.654700  [show with all ESTs]
    Unigene Representative Sequence: AK126219
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336755(uc003zzq.3 uc011lqh.2 uc022bgu.1) ENST00000322831(uc003zzs.1)
    ENST00000461038(uc010mlt.3) ENST00000488607 ENST00000463625 ENST00000497924
    ENST00000481507 ENST00000496099 ENST00000534928
    miRNA
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    Block miRNA regulation of human, mouse, rat ZCCHC7 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZCCHC7:
    hsa-miR-1236
    SwitchGear 3'UTR luciferase reporter plasmidZCCHC7 3' UTR sequence
    Inhib. RNA
    Products:
         
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    GenScript: all cDNA clones in your preferred vector: ZCCHC7 (NM_032226)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZCCHC7
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    Primer
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    OriGene qPCR primer pairs and template standards for ZCCHC7
    OriGene qSTAR qPCR primer pairs in human, mouse for ZCCHC7
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZCCHC7
      QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC7
      QuantiFast Probe-based Assays in human, mouse, rat ZCCHC7

    Additional mRNA sequence: 

    AF161349.1 AK026264.1 AK074608.1 AK126219.1 AK303193.1 AK315128.1 BC005990.1 BC022434.1 
    BC034022.1 BC036940.1 

    Selected DOTS entries (see all 28):

    DT.443289  DT.100810767  DT.100810774  DT.95160700  DT.91758828  DT.40263362  DT.439657  DT.121196594 
    DT.205246  DT.70102780  DT.91758811  DT.91758814  DT.100700157  DT.100810768  DT.410989  DT.91758824 
    DT.100768029  DT.100810770  DT.100810771  DT.121196628  DT.100810773  DT.120729579  DT.121196727  DT.121196737 

    Selected AceView cDNA sequences (see all 272):

    BE295251 BX352833 BC005990 AI914255 BP344330 CB122221 CR621518 BX388557 
    AL709194 BE675698 AK126219 BM469725 BE081597 CR611439 BQ231508 BG530318 
    N28270 AI418466 AW139513 BG613852 BQ422572 BX388667 AA953501 AI701803 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC7 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16 ^
    SP1:                                -     -     -     -                       -     -     -     -     -     -     -                       -     -               
    SP2:                                -     -     -     -                       -     -     -     -     -     -     -                       -     -               
    SP3:                                            -     -                       -     -     -     -     -     -     -                       -     -               
    SP4:                                                                                                                                      -     -               
    SP5:                                      -     -                             -     -     -     -                                                               

    ExUns: 17
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ZCCHC7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZCCHC7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAAGCAAC
    ZCCHC7 Expression
    About this image


    ZCCHC7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Blood (Hematopoietic System)
             Mature B-Cells Peripheral Blood
     
     Eye (Sensory Organs)
             Lens
     
     Neural Tube (Nervous System)
             Metencephalon
    ZCCHC7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZCCHC7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654700
        Custom PCR Arrays for ZCCHC7
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ZCCHC7 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zcchc71 , 5 zinc finger, CCHC domain containing 71, 5 78.59(n)1
    65.92(a)1
      4 (23.57 cM)5
    3198851  NM_138590.41  NP_613056.21 
     447558775 
    chicken
    (Gallus gallus)
    Aves LOC1017515251 zinc finger CCHC domain-containing protein 7-like 59.82(n)
    50.53(a)
      101751525  XM_004950834.1  XP_004950891.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZCCHC76
    zinc finger, CCHC domain containing 7
    41(a)
    1 ↔ 1
    GL343201.1(3459862-3592113)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.194672 Xenopus laevis transcribed sequence with weak similarity more 76.52(n)    BU901366.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zcchc71 zinc finger, CCHC domain containing 7 49.9(n)
    41.04(a)
      317641  XM_001332506.5  XP_001332542.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG97156
    --
    6(a)
    1 ↔ 1
    3L(16838486-16845450)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes AIR2(YDL175C)4 Zinc knuckle protein, involved in nuclear RNA processing more   --   4(145518-144484) 851379  NP_010106.1 


    ENSEMBL Gene Tree for ZCCHC7 (if available)
    TreeFam Gene Tree for ZCCHC7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZCCHC7 gene

    Find genes that share paralogs with ZCCHC7           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for ZCCHC7
    PGOHUM00000247812 PGOHUM00000248182


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZCCHC7 (see all 3935)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1849409981,2
    --37118490(+) TCTCTC/TTTGCT 1 -- us2k10--------
    rs1155909201,2
    C,F--37118558(+) TTAAAG/ACGATT 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1416313191,2
    --37118859(+) CACTTC/TGGGCT 1 -- us2k10--------
    rs123387321,2
    C--37119267(+) gcctgA/Gccaac 1 -- us2k10--------
    rs1382917151,2
    C--37119301(+) AAAATA/GCAAAA 1 -- us2k10--------
    rs123387701,2
    C,A--37119368(+) aggagA/Gatggc 1 -- us2k12Minor allele frequency- G:0.33NA CSA 3
    rs120001911,2
    C,H--37119528(+) TACAAG/AAAgtg 1 -- us2k15Minor allele frequency- A:0.00NS EA NA 422
    rs78610991,2
    C,F,A,H--37119544(+) gctcaT/Cgcctg 1 -- us2k120Minor allele frequency- C:0.47NS EA NA WA CSA 2343
    rs120022631,2
    H--37119559(+) cccagG/Tgcttt 1 -- us2k10--------
    rs1503653701,2
    --37119799(+) TTGTAG/TTAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZCCHC7 (37120469 - 37358146 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ZCCHC7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv994123CNV Deletion20482838
    nsv6535CNV Insertion18451855
    esv271260CNV Insertion20981092
    nsv6534CNV Insertion18451855
    nsv466390CNV Loss19166990
    nsv520965CNV Loss19592680
    nsv529027CNV Loss19592680
    nsv893056CNV Gain21882294
    nsv893057CNV Gain21882294
    nsv831551CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZCCHC7           About GenesLikeMe

    Genetic Association Database (GAD): ZCCHC7

    Export disorders for ZCCHC7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZCCHC7 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with ZCCHC7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Comparison of the yeast and human nuclear exosome complexes. (PubMed id 22817747)2 Sloan K.E.... Watkins N.J. (Biochem. Soc. Trans. 2012)
    7. Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex. (PubMed id 21878619)1 Fasken M.B....Corbett A.H. (J. Biol. Chem. 2011)
    8. Interaction profiling identifies the human nuclear exosome targeting complex. (PubMed id 21855801)2 Lubas M....Jensen T.H. (Mol. Cell 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (EMBO Rep. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84186 HGNC: 26209 AceView: ZCCHC7 Ensembl:ENSG00000147905 euGenes: HUgn84186
    ECgene: ZCCHC7 Kegg: 84186 H-InvDB: ZCCHC7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZCCHC7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZCCHC7 gene:
    Search GeneIP for patents involving ZCCHC7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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