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ZCCHC6 Gene

protein-coding   GIFtS: 49
GCID: GC09M088902

Zinc Finger, CCHC Domain Containing 6

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, CCHC Domain Containing 61 2     PAP Associated Domain Containing 62
Zinc Finger CCHC Domain-Containing Protein 62 3     Terminal Uridylyltransferase 72
TUT72 3     EC 2.7.7.523
TUTase 72 3     HS23
TUTase71     KIAA17113
PAPD62     

External Ids:    HGNC: 258171   Entrez Gene: 796702   Ensembl: ENSG000000832237   UniProtKB: Q5VYS83   

Export aliases for ZCCHC6 gene to outside databases

Previous GC identifers: GC09M084359 GC09M086132 GC09M088093 GC09M058725


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZCCHC6 Gene:
ZCCHC6 (zinc finger, CCHC domain containing 6) is a protein-coding gene. GO annotations related to this gene include RNA uridylyltransferase activity and nucleic acid binding. An important paralog of this gene is TUT1.

UniProtKB/Swiss-Prot: TUT7_HUMAN, Q5VYS8
Function: Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in
uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA
degradation

Gene Wiki entry for ZCCHC6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZCCHC6 gene promoter:
         CRE-BP1   Ik-2   POU2F1   Nkx6-1   ATF-2   POU2F1a   FOXO1a   CUTL1   NF-kappaB1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZCCHC6 promoter sequence
   Search Chromatin IP Primers for ZCCHC6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZCCHC6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21   Ensembl cytogenetic band:  9q21.33   HGNC cytogenetic band: 9q21

ZCCHC6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZCCHC6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M088902:  view genomic region     (about GC identifiers)

Start:
88,902,648 bp from pter      End:
88,969,402 bp from pter
Size:
66,755 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TUT7_HUMAN, Q5VYS8 (See protein sequence)
Recommended Name: Terminal uridylyltransferase 7  
Size: 1495 amino acids; 171229 Da
Cofactor: Magnesium or manganese (By similarity)
Sequence caution: Sequence=BAB14584.1; Type=Erroneous initiation; Sequence=BAB71052.1; Type=Erroneous initiation;
Secondary accessions: Q5H9T0 Q5VYS5 Q5VYS7 Q658Z9 Q659A2 Q6MZJ3 Q8N5F0 Q96N57 Q96NE8 Q9C0F2
Q9H8M6
Alternative splicing: 6 isoforms:  Q5VYS8-1   Q5VYS8-2   Q5VYS8-3   Q5VYS8-4   Q5VYS8-5   Q5VYS8-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZCCHC6: NX_Q5VYS8

Explore proteomics data for ZCCHC6 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys11, Lys602
  • Modification sites at PhosphoSitePlus

  • See ZCCHC6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001171988.1  NP_001172003.1  NP_078893.2  

    ENSEMBL proteins: 
     ENSP00000277141   ENSP00000365127   ENSP00000365124   ENSP00000365130   ENSP00000365115  
     ENSP00000365114   ENSP00000365128  

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    Cloud-Clone Corp. Proteins for ZCCHC6

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZCCHC: Zinc fingers, CCHC domain containing

    2 InterPro protein domains:
     IPR002058 PAP_assoc
     IPR001878 Znf_CCHC

    Graphical View of Domain Structure for InterPro Entry Q5VYS8

    ProtoNet protein and cluster: Q5VYS8

    2 Blocks protein domains:
    IPB002058 PAP/25A-associated domain
    IPB002934 DNA polymerase


    UniProtKB/Swiss-Prot: TUT7_HUMAN, Q5VYS8
    Similarity: Belongs to the DNA polymerase type-B-like family
    Similarity: Contains 3 CCHC-type zinc fingers
    Similarity: Contains 2 PAP-associated domains


    Find genes that share domains with ZCCHC6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TUT7_HUMAN, Q5VYS8
    Function: Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in
    uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA
    degradation
    Catalytic activity: UTP + RNA(n) = diphosphate + RNA(n+1)

         Enzyme Number (IUBMB): EC 2.7.7.521

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0008270zinc ion binding IEA--
    GO:0044822poly(A) RNA binding IDA--
    GO:0050265RNA uridylyltransferase activity IDA17353264
         
    Find genes that share ontologies with ZCCHC6           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZCCHC6

    miRNA
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    miRTarBase miRNAs that target ZCCHC6:
    hsa-mir-335-5p (MIRT017605), hsa-mir-629-5p (MIRT037782)

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    Selected qRT-PCR Assays for microRNAs that regulate ZCCHC6 (see all 19):
    hsa-miR-548j hsa-miR-548i hsa-miR-205* hsa-miR-3662 hsa-miR-548d-5p hsa-miR-548a-5p hsa-miR-4293 hsa-miR-548c-3p
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZCCHC6
    Interactions:

        Search GeneGlobe Interaction Network for ZCCHC6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZCCHC6 (Q5VYS83 ENSP000003651304) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLN3Q132863I2D: score=1 
    PDCD11ENSP000003588124STRING: ENSP00000358812
    EXOSC10ENSP000003661354STRING: ENSP00000366135
    GLTSCR2ENSP000002468024STRING: ENSP00000246802
    METTL1ENSP000003144414STRING: ENSP00000314441
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031123RNA 3'-end processing IDA17353264
    GO:0071044NOT histone mRNA catabolic process IMP18172165

    Find genes that share ontologies with ZCCHC6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZCCHC6 (TUT7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZCCHC6 gene (3 alternative transcripts): 
    NM_001185059.1  NM_001185074.1  NM_024617.3  

    Unigene Cluster for ZCCHC6:

    Zinc finger, CCHC domain containing 6
    Hs.597057  [show with all ESTs]
    Unigene Representative Sequence: NM_024617
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000277141(uc011ltf.2 uc004aou.3 uc004aoq.3 uc004aor.3 uc004aos.3)
    ENST00000375960(uc004aot.3 uc010mqf.2) ENST00000375957 ENST00000375963
    ENST00000469004 ENST00000375948 ENST00000375947 ENST00000375961(uc010mqe.3 uc004aov.3 uc004aow.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZCCHC6 (see all 19):
    hsa-miR-548j hsa-miR-548i hsa-miR-205* hsa-miR-3662 hsa-miR-548d-5p hsa-miR-548a-5p hsa-miR-4293 hsa-miR-548c-3p
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      QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC6
      QuantiFast Probe-based Assays in human, mouse, rat ZCCHC6

    Additional mRNA sequence: 

    AB051498.1 AK023471.1 AK055546.1 AK055948.1 AK058021.1 AK094169.1 AK308352.1 AL832026.1 
    AL832965.1 AL832988.1 BC015897.1 BC016387.1 BC032456.1 BC111003.1 BX640659.1 CR933643.1 

    22 DOTS entries:

    DT.100789317  DT.100789316  DT.40108224  DT.310907  DT.409474  DT.100789320  DT.411143  DT.91972968 
    DT.110986  DT.100789323  DT.75182369  DT.87046278  DT.91843233  DT.121152427  DT.121152464  DT.121152430 
    DT.121152441  DT.40280209  DT.455848  DT.86847048  DT.92015852  DT.92427730 

    Selected AceView cDNA sequences (see all 146):

    BQ020750 BX491541 AK055948 BX111702 CA773862 BU734789 CR620723 CR616935 
    AA459801 BM142103 AI472675 BC032456 AW104198 BU618655 CB160822 AW628308 
    AK055546 CD722458 AB051498 AL528585 CB161503 CK819900 AA809435 CA424334 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC6 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^
    SP1:                                                                                                                                                            
    SP2:                                                              -                 -                       -                                                   
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                              -                                                                                             

    ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29
    SP1:                                                              -     -         
    SP2:                                                                              
    SP3:              -                                               -     -         
    SP4:                                                                              
    SP5:                                                                              


    ECgene alternative splicing isoforms for ZCCHC6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZCCHC6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTTTTAATT
    ZCCHC6 Expression
    About this image


    ZCCHC6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 6 entries
             Zeugopod Long Bone
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             Pelvic Girdle
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Cartilage (Muscoskeletal System)
             Meckel's Cartilage
    ZCCHC6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZCCHC6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.597057
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZCCHC6 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zcchc61 , 5 zinc finger, CCHC domain containing 61, 5 82.53(n)1
    81.46(a)1
      13 (31.88 cM)5
    2142901  NM_153538.31  NP_705766.31 
     597718795 
    chicken
    (Gallus gallus)
    Aves ZCCHC61 zinc finger, CCHC domain containing 6 71.25(n)
    66.62(a)
      100857368  NM_001271947.1  NP_001258876.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZCCHC66
    zinc finger, CCHC domain containing 6
    75(a)
    1 ↔ 1
    2(41708663-41745711)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.7562 Transcribed sequence with weak similarity to protein more 75.89(n)    CF153319.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5623581 terminal uridylyltransferase 7-like 55.18(n)
    52.36(a)
      562358  XM_685750.6  XP_690842.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta mkg-p6
    monkey king protein
    14(a)
    many ↔ many
    3L(8395268-8398377)
    worm
    (Caenorhabditis elegans)
    Secernentea pup-26
    Y34F4.36
    (see all 4)
    Protein Y34F4.3 (Y34F4.3) mRNA, complete cds
    (see all 4)
    25(a)
    20(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    III(5185920-5188647) WBGene00019628
    III(1015680-1016136) WBGene00021338


    ENSEMBL Gene Tree for ZCCHC6 (if available)
    TreeFam Gene Tree for ZCCHC6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZCCHC6 gene
    TUT12  MTPAP2  ZCCHC112  PAPD42  
    1 SIMAP similar gene for ZCCHC6 using alignment to 4 protein entries:     TUT7_HUMAN (see all proteins):
    ZCCHC11

    Find genes that share paralogs with ZCCHC6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZCCHC6 (see all 1310)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1389971861,2
    C--88902148(+) GTTGCA/GTCATT 3 -- int10--------
    rs1925672701,2
    --88902152(+) CGTCAC/TTCATT 3 -- int10--------
    rs107807561,2
    C,F,A,H--88902165(+) TTTGCG/ATTCAA 3 -- int124Minor allele frequency- A:0.45NS EA NA WA 2712
    rs1836823071,2
    --88902172(+) TCAAAA/GTGAGT 3 -- int10--------
    rs794233561,2
    C--88902232(+) TTTAAG/TTTTGA 3 -- int10--------
    rs1157350671,2
    F--88902304(+) TGTGCG/ATCTTC 3 -- int11Minor allele frequency- A:0.09WA 118
    rs1878692191,2
    --88902378(+) TTCCCC/TGCCCC 3 -- int10--------
    rs1925485171,2
    --88902445(+) ACACAA/CTGGAT 3 -- int10--------
    rs108684051,2
    C,F,A,H--88902561(+) TACTAT/GCATTC 3 -- int112Minor allele frequency- G:0.41NA WA EA 512
    rs1850392051,2
    --88902600(+) TTTTTC/TCCCCA 3 -- int10--------

    HapMap Linkage Disequilibrium report for ZCCHC6 (88902648 - 88969402 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZCCHC6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv518696CNV Loss19592680
    nsv893539CNV Loss21882294
    nsv893538CNV Gain21882294
    nsv893536CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZCCHC6
    DNA2.0 Custom Variant and Variant Library Synthesis for ZCCHC6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZCCHC6           About GenesLikeMe

    Genetic Association Database (GAD): ZCCHC6

    Export disorders for ZCCHC6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZCCHC6 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with ZCCHC6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'. (PubMed id 18172165)1, 2 Mullen T.E. and Marzluff W.F. (Genes Dev. 2008)
    3. Efficient RNA polyuridylation by noncanonical poly(A) polymerases. (PubMed id 17353264)1, 2 Rissland O.S.... Norbury C.J. (Mol. Cell. Biol. 2007)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). (PubMed id 22898984)1 Thornton J.E....Gregory R.I. (RNA 2012)
    9. Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs. (PubMed id 23063654)1 Heo I....Kim V.N. (Cell 2012)
    10. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79670 HGNC: 25817 AceView: ZCCHC6 Ensembl:ENSG00000083223 euGenes: HUgn79670
    ECgene: ZCCHC6 H-InvDB: ZCCHC6

    (According to HUGE)
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    HUGE: KIAA1711

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZCCHC6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZCCHC6 gene:
    Search GeneIP for patents involving ZCCHC6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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