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Aliases for ZCCHC5 Gene

Aliases for ZCCHC5 Gene

  • Zinc Finger, CCHC Domain Containing 5 2 3
  • Zinc Finger CCHC Domain-Containing Protein 5 3
  • Mammalian Retrotransposon-Derived 3 3
  • Mart3 3
  • Mar3 3
  • ZHC5 3

External Ids for ZCCHC5 Gene

Summaries for ZCCHC5 Gene

Entrez Gene Summary for ZCCHC5 Gene

  • This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell. [provided by RefSeq, Nov 2009]

GeneCards Summary for ZCCHC5 Gene

ZCCHC5 (Zinc Finger, CCHC Domain Containing 5) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is PEG10.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC5 Gene

Genomics for ZCCHC5 Gene

Genomic Location for ZCCHC5 Gene

Start:
78,656,069 bp from pter
End:
78,659,328 bp from pter
Size:
3,260 bases
Orientation:
Minus strand

Genomic View for ZCCHC5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZCCHC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC5 Gene

Regulatory Elements for ZCCHC5 Gene

Proteins for ZCCHC5 Gene

  • Protein details for ZCCHC5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8U3-ZCHC5_HUMAN
    Recommended name:
    Zinc finger CCHC domain-containing protein 5
    Protein Accession:
    Q8N8U3
    Secondary Accessions:
    • B2RMZ0
    • Q5JQE9

    Protein attributes for ZCCHC5 Gene

    Size:
    475 amino acids
    Molecular mass:
    52817 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZCCHC5 Gene

Proteomics data for ZCCHC5 Gene at MOPED

Post-translational modifications for ZCCHC5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZCCHC5 Gene

Domains for ZCCHC5 Gene

Gene Families for ZCCHC5 Gene

HGNC:
  • ZCCHC :Zinc fingers, CCHC domain containing

Protein Domains for ZCCHC5 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

ZCHC5_HUMAN
Similarity:
  • Contains 1 CCHC-type zinc finger.:
    • Q8N8U3
genes like me logo Genes that share domains with ZCCHC5: view

Function for ZCCHC5 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZCCHC5: view

miRNA for ZCCHC5 Gene

miRTarBase miRNAs that target ZCCHC5

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZCCHC5 Gene

Localization for ZCCHC5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZCCHC5 Gene COMPARTMENTS Subcellular localization image for ZCCHC5 gene
Compartment Confidence
cytoskeleton 2
cytosol 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for ZCCHC5 Gene

Pathways for ZCCHC5 Gene

SuperPathways for ZCCHC5 Gene

No Data Available

Interacting Proteins for ZCCHC5 Gene

Gene Ontology (GO) - Biological Process for ZCCHC5 Gene

None

No data available for Pathways by source for ZCCHC5 Gene

Transcripts for ZCCHC5 Gene

mRNA/cDNA for ZCCHC5 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZCCHC5 Gene

Zinc finger, CCHC domain containing 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC5 Gene

No ASD Table

Relevant External Links for ZCCHC5 Gene

GeneLoc Exon Structure for
ZCCHC5
ECgene alternative splicing isoforms for
ZCCHC5

Expression for ZCCHC5 Gene

mRNA expression in normal human tissues for ZCCHC5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZCCHC5 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (7.8), Artery - Aorta (6.5), and Esophagus - Muscularis (5.8).

SOURCE GeneReport for Unigene cluster for ZCCHC5 Gene Hs.134873

genes like me logo Genes that share expressions with ZCCHC5: view

Orthologs for ZCCHC5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZCCHC5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZCCHC5 36
  • 98.88 (n)
  • 97.26 (a)
cow
(Bos Taurus)
Mammalia ZCCHC5 36
  • 75.3 (n)
  • 61.28 (a)
ZCCHC5 37
  • 52 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZCCHC5 36
  • 75.58 (n)
  • 59.73 (a)
mouse
(Mus musculus)
Mammalia Zcchc5 36
  • 70.55 (n)
  • 56.8 (a)
Zcchc5 16
Zcchc5 37
  • 46 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zcchc5 36
  • 71.99 (n)
  • 55.16 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 30 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 31 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 31 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 31 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 25 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 26 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 31 (a)
ManyToMany
Species with no ortholog for ZCCHC5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZCCHC5 Gene

ENSEMBL:
Gene Tree for ZCCHC5 (if available)
TreeFam:
Gene Tree for ZCCHC5 (if available)

Paralogs for ZCCHC5 Gene

Paralogs for ZCCHC5 Gene

genes like me logo Genes that share paralogs with ZCCHC5: view

Variants for ZCCHC5 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs4077512 - 78,658,072(+) TGGAG(A/G)CGCCA reference, missense
rs4317713 -- 78,660,301(+) TAAAA(A/G)CAAAA upstream-variant-2KB
rs4532723 -- 78,660,282(+) AATGC(A/G)GAAGC upstream-variant-2KB
rs4565596 -- 78,659,999(+) GCTCA(A/G)AATCT upstream-variant-2KB
rs7471745 -- 78,660,233(+) GAATA(C/G)GCCCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZCCHC5 Gene

Variant ID Type Subtype PubMed ID
dgv517n21 CNV Gain 19592680

Relevant External Links for ZCCHC5 Gene

HapMap Linkage Disequilibrium report
ZCCHC5
Locus Specific Mutation Databases (LSDB)
ZCCHC5

Disorders for ZCCHC5 Gene

No disorders were found for ZCCHC5 Gene.

No data available for UniProtKB/Swiss-Prot for ZCCHC5 Gene

Publications for ZCCHC5 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. (PMID: 15716091) Brandt J. … Volff J.-N. (Gene 2005) 2 3
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. (PMID: 16093683) Brandt J. … Volff J.-N. (Cytogenet. Genome Res. 2005) 2 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ZCCHC5 Gene

Sources for ZCCHC5 Gene

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