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Aliases for ZCCHC5 Gene

Aliases for ZCCHC5 Gene

  • Zinc Finger CCHC-Type Containing 5 2 3
  • Zinc Finger, CCHC Domain Containing 5 3 5
  • Mammalian Retrotransposon-Derived 3 3
  • Mart3 3
  • MAR3 3
  • ZHC5 3

External Ids for ZCCHC5 Gene

Previous GeneCards Identifiers for ZCCHC5 Gene

  • GC0XM075952
  • GC0XM076667
  • GC0XM077717
  • GC0XM077798
  • GC0XM077911
  • GC0XM071491

Summaries for ZCCHC5 Gene

Entrez Gene Summary for ZCCHC5 Gene

  • This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell. [provided by RefSeq, Nov 2009]

GeneCards Summary for ZCCHC5 Gene

ZCCHC5 (Zinc Finger CCHC-Type Containing 5) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZCCHC16.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC5 Gene

Genomics for ZCCHC5 Gene

Regulatory Elements for ZCCHC5 Gene

Enhancers for ZCCHC5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZCCHC5 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZCCHC5 Gene

Chromosome:
X
Start:
78,656,069 bp from pter
End:
78,659,502 bp from pter
Size:
3,434 bases
Orientation:
Minus strand

Genomic View for ZCCHC5 Gene

Genes around ZCCHC5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZCCHC5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZCCHC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC5 Gene

Proteins for ZCCHC5 Gene

  • Protein details for ZCCHC5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8U3-ZCHC5_HUMAN
    Recommended name:
    Zinc finger CCHC domain-containing protein 5
    Protein Accession:
    Q8N8U3
    Secondary Accessions:
    • B2RMZ0
    • Q5JQE9

    Protein attributes for ZCCHC5 Gene

    Size:
    475 amino acids
    Molecular mass:
    52817 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZCCHC5 Gene

Proteomics data for ZCCHC5 Gene at MOPED

Post-translational modifications for ZCCHC5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZCCHC5 Gene

Domains & Families for ZCCHC5 Gene

Gene Families for ZCCHC5 Gene

Protein Domains for ZCCHC5 Gene

Suggested Antigen Peptide Sequences for ZCCHC5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8U3

UniProtKB/Swiss-Prot:

ZCHC5_HUMAN :
  • Contains 1 CCHC-type zinc finger.
Similarity:
  • Contains 1 CCHC-type zinc finger.
genes like me logo Genes that share domains with ZCCHC5: view

Function for ZCCHC5 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZCCHC5: view
genes like me logo Genes that share phenotypes with ZCCHC5: view

Animal Model Products

miRNA for ZCCHC5 Gene

miRTarBase miRNAs that target ZCCHC5

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZCCHC5 Gene

Localization for ZCCHC5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZCCHC5 Gene COMPARTMENTS Subcellular localization image for ZCCHC5 gene
Compartment Confidence
cytoskeleton 2
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC5 Gene

Pathways & Interactions for ZCCHC5 Gene

SuperPathways for ZCCHC5 Gene

No Data Available

Interacting Proteins for ZCCHC5 Gene

Gene Ontology (GO) - Biological Process for ZCCHC5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZCCHC5 Gene

Drugs & Compounds for ZCCHC5 Gene

No Compound Related Data Available

Transcripts for ZCCHC5 Gene

mRNA/cDNA for ZCCHC5 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZCCHC5 Gene

Zinc finger, CCHC domain containing 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC5 Gene

No ASD Table

Relevant External Links for ZCCHC5 Gene

GeneLoc Exon Structure for
ZCCHC5
ECgene alternative splicing isoforms for
ZCCHC5

Expression for ZCCHC5 Gene

mRNA expression in normal human tissues for ZCCHC5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZCCHC5 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (x7.8), Artery - Aorta (x6.5), and Esophagus - Muscularis (x5.8).

SOURCE GeneReport for Unigene cluster for ZCCHC5 Gene Hs.134873

genes like me logo Genes that share expression patterns with ZCCHC5: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZCCHC5 Gene

Orthologs for ZCCHC5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZCCHC5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZCCHC5 35
  • 75.3 (n)
  • 61.28 (a)
ZCCHC5 36
  • 52 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZCCHC5 35
  • 75.58 (n)
  • 59.73 (a)
mouse
(Mus musculus)
Mammalia Zcchc5 35
  • 70.55 (n)
  • 56.8 (a)
Zcchc5 16
Zcchc5 36
  • 46 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZCCHC5 35
  • 98.88 (n)
  • 97.26 (a)
rat
(Rattus norvegicus)
Mammalia Zcchc5 35
  • 71.99 (n)
  • 55.16 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 30 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 25 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
Species with no ortholog for ZCCHC5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZCCHC5 Gene

ENSEMBL:
Gene Tree for ZCCHC5 (if available)
TreeFam:
Gene Tree for ZCCHC5 (if available)

Paralogs for ZCCHC5 Gene

Paralogs for ZCCHC5 Gene

genes like me logo Genes that share paralogs with ZCCHC5: view

Variants for ZCCHC5 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs4077512 - 78,658,072(+) TGGAG(A/G)CGCCA reference, missense
rs747741103 -- 78,658,145(+) AGATC(C/T)TGTGG reference, synonymous-codon
rs747871202 -- 78,658,035(+) CATGG(A/G)CCATT reference, missense
rs748229681 -- 78,657,414(+) ACCCT(-/C)CCCCT reference, frameshift-variant
rs748276891 -- 78,657,116(+) ACCCA(C/T)TCAGC reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZCCHC5 Gene

Variant ID Type Subtype PubMed ID
dgv517n21 CNV Gain 19592680

Variation tolerance for ZCCHC5 Gene

Residual Variation Intolerance Score: 84.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.28; 40.84% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZCCHC5 Gene

Disorders for ZCCHC5 Gene

Relevant External Links for ZCCHC5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZCCHC5

No disorders were found for ZCCHC5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC5 Gene

Publications for ZCCHC5 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. (PMID: 15716091) Brandt J. … Volff J.-N. (Gene 2005) 2 3
  3. A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. (PMID: 16093683) Brandt J. … Volff J.-N. (Cytogenet. Genome Res. 2005) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZCCHC5 Gene

Sources for ZCCHC5 Gene

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