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Aliases for ZCCHC4 Gene

Aliases for ZCCHC4 Gene

  • Zinc Finger, CCHC Domain Containing 4 2 3
  • Zinc Finger CCHC Domain-Containing Protein 4 3
  • DHHC Domain-Containing Zinc Finger Protein 3
  • Zinc Finger, GRF-Type Containing 4 3
  • GRF-Type Containing 4 2
  • Zinc Finger 2
  • HSPC052 3
  • ZGRF4 3

External Ids for ZCCHC4 Gene

Previous GeneCards Identifiers for ZCCHC4 Gene

  • GC04U900073
  • GC04P025065
  • GC04P024990
  • GC04P024923
  • GC04P024654

Summaries for ZCCHC4 Gene

GeneCards Summary for ZCCHC4 Gene

ZCCHC4 (Zinc Finger, CCHC Domain Containing 4) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and methyltransferase activity.

UniProtKB/Swiss-Prot for ZCCHC4 Gene

  • May be a methyltransferase

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC4 Gene

Genomics for ZCCHC4 Gene

Regulatory Elements for ZCCHC4 Gene

Genomic Location for ZCCHC4 Gene

Start:
25,312,774 bp from pter
End:
25,370,383 bp from pter
Size:
57,610 bases
Orientation:
Plus strand

Genomic View for ZCCHC4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZCCHC4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC4 Gene

Proteins for ZCCHC4 Gene

  • Protein details for ZCCHC4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H5U6-ZCHC4_HUMAN
    Recommended name:
    Zinc finger CCHC domain-containing protein 4
    Protein Accession:
    Q9H5U6
    Secondary Accessions:
    • B2RXF6
    • B4DRD8
    • B7ZW20
    • Q5IW78
    • Q96AN7

    Protein attributes for ZCCHC4 Gene

    Size:
    513 amino acids
    Molecular mass:
    59010 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH16914.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB15524.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZCCHC4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZCCHC4 Gene

Proteomics data for ZCCHC4 Gene at MOPED

Post-translational modifications for ZCCHC4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC4 Gene

No data available for DME Specific Peptides for ZCCHC4 Gene

Domains for ZCCHC4 Gene

Gene Families for ZCCHC4 Gene

HGNC:
  • ZCCHC :Zinc fingers, CCHC domain containing

Suggested Antigen Peptide Sequences for ZCCHC4 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H5U6

UniProtKB/Swiss-Prot:

ZCHC4_HUMAN :
  • Q9H5U6
Similarity:
  • Contains 1 CCHC-type zinc finger.
  • Contains 1 DHHC-type zinc finger.
genes like me logo Genes that share domains with ZCCHC4: view

Function for ZCCHC4 Gene

Molecular function for ZCCHC4 Gene

UniProtKB/Swiss-Prot Function: May be a methyltransferase

Gene Ontology (GO) - Molecular Function for ZCCHC4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0008168 methyltransferase activity IEA --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZCCHC4: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZCCHC4 Gene

Localization for ZCCHC4 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZCCHC4 Gene COMPARTMENTS Subcellular localization image for ZCCHC4 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC4 Gene

Pathways for ZCCHC4 Gene

SuperPathways for ZCCHC4 Gene

No Data Available

Interacting Proteins for ZCCHC4 Gene

Gene Ontology (GO) - Biological Process for ZCCHC4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with ZCCHC4: view

No data available for Pathways by source for ZCCHC4 Gene

Transcripts for ZCCHC4 Gene

Unigene Clusters for ZCCHC4 Gene

Zinc finger, CCHC domain containing 4:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZCCHC4

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZCCHC4

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC4 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b
SP1:
SP2: - - - -
SP3:
SP4: - -
SP5: -

Relevant External Links for ZCCHC4 Gene

GeneLoc Exon Structure for
ZCCHC4
ECgene alternative splicing isoforms for
ZCCHC4

Expression for ZCCHC4 Gene

mRNA expression in normal human tissues for ZCCHC4 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZCCHC4 Gene

SOURCE GeneReport for Unigene cluster for ZCCHC4 Gene Hs.278945

genes like me logo Genes that share expressions with ZCCHC4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZCCHC4 Gene

Orthologs for ZCCHC4 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZCCHC4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZCCHC4 35
  • 99.15 (n)
  • 99.02 (a)
ZCCHC4 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZCCHC4 35
  • 90.32 (n)
  • 88.5 (a)
ZCCHC4 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZCCHC4 35
  • 91.16 (n)
  • 89.27 (a)
ZCCHC4 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zcchc4 35
  • 82.52 (n)
  • 81.66 (a)
Zcchc4 16
Zcchc4 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZCCHC4 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZCCHC4 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zcchc4 35
  • 86.3 (n)
  • 85.93 (a)
chicken
(Gallus gallus)
Aves ZCCHC4 35
  • 67.28 (n)
  • 65.04 (a)
ZCCHC4 36
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZCCHC4 36
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zcchc4 35
  • 64.45 (n)
  • 65.35 (a)
zebrafish
(Danio rerio)
Actinopterygii ZCCHC4 36
  • 55 (a)
OneToOne
zgc:172248 35
  • 60.94 (n)
  • 58.8 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12863 35
  • 49.08 (n)
  • 39.58 (a)
CG12863 36
  • 34 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F33A8.4 35
  • 45.91 (n)
  • 33.51 (a)
F33A8.4 36
  • 27 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 40 (a)
OneToOne
Species with no ortholog for ZCCHC4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZCCHC4 Gene

ENSEMBL:
Gene Tree for ZCCHC4 (if available)
TreeFam:
Gene Tree for ZCCHC4 (if available)

Paralogs for ZCCHC4 Gene

No data available for Paralogs for ZCCHC4 Gene

Variants for ZCCHC4 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC4 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs167584 -- 25,346,701(-) tttaa(C/T)ggctt intron-variant
rs178427 -- 25,348,882(-) AAGCT(C/T)TTTTA intron-variant
rs184360 -- 25,360,479(-) agtta(C/T)gaact intron-variant
rs188819 -- 25,360,496(-) ctgaa(C/G)ggcag intron-variant
rs315673 -- 25,366,906(-) TAAAC(C/T)TGATA intron-variant

Relevant External Links for ZCCHC4 Gene

HapMap Linkage Disequilibrium report
ZCCHC4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZCCHC4 Gene

Disorders for ZCCHC4 Gene

No disorders were found for ZCCHC4 Gene.

No data available for UniProtKB/Swiss-Prot for ZCCHC4 Gene

Publications for ZCCHC4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. (PMID: 15225602) Albrecht M. … Lengauer T. (FEBS Lett. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZCCHC4 Gene

  • antibodies-online proteins for ZCCHC4
  • antibodies-online antibodies for ZCCHC4
  • antibodies-online kits for ZCCHC4

Sources for ZCCHC4 Gene

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