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ZCCHC4 Gene

protein-coding   GIFtS: 41
GCID: GC04P025314

Zinc Finger, CCHC Domain Containing 4

  Search for ZCCHC4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, CCHC Domain Containing 41 2     ZGRF42
GRF-Type Containing 41     DHHC Domain-Containing Zinc Finger Protein2
Zinc Finger1     Zinc Finger CCHC Domain-Containing Protein 42
HSPC0522     Zinc Finger, GRF-Type Containing 42

External Ids:    HGNC: 229171   Entrez Gene: 290632   Ensembl: ENSG000001682287   OMIM: 6117925   UniProtKB: Q9H5U63   

Export aliases for ZCCHC4 gene to outside databases

Previous GC identifers: GC04U900073 GC04P025065 GC04P024990 GC04P024923 GC04P024654


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZCCHC4 Gene:
ZCCHC4 (zinc finger, CCHC domain containing 4) is a protein-coding gene. GO annotations related to this gene include methyltransferase activity and nucleic acid binding.

UniProtKB/Swiss-Prot: ZCHC4_HUMAN, Q9H5U6
Function: May be a methyltransferase




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_006316.17  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZCCHC4 gene promoter:
         c-Fos   AP-1   RREB-1   JunB   Fra-1   FosB   CUTL1   GATA-1   JunD   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZCCHC4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZCCHC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.2   Ensembl cytogenetic band:  4p15.2   HGNC cytogenetic band: 4p15.31

ZCCHC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZCCHC4 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P025314:  view genomic region     (about GC identifiers)

Start:
25,314,396 bp from pter      End:
25,372,005 bp from pter
Size:
57,610 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZCHC4_HUMAN, Q9H5U6 (See protein sequence)
Recommended Name: Zinc finger CCHC domain-containing protein 4  
Size: 513 amino acids; 59010 Da
Sequence caution: Sequence=AAH16914.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB15524.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B2RXF6 B4DRD8 B7ZW20 Q5IW78 Q96AN7
Alternative splicing: 3 isoforms:  Q9H5U6-1   Q9H5U6-2   Q9H5U6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZCCHC4: NX_Q9H5U6

Explore proteomics data for ZCCHC4 at MOPED


See ZCCHC4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_079212.2  
ENSEMBL proteins: 
 ENSP00000303468   ENSP00000422115   ENSP00000422269  

ZCCHC4 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for ZCCHC4
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Novus Biologicals ZCCHC4 Protein
Novus Biologicals ZCCHC4 Lysate
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Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for ZCCHC4

 
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ZCCHC4 Antibody Products:

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ThermoFisher Antibody for ZCCHC4
LSBio Antibodies in human, mouse, rat for ZCCHC4

ZCCHC4 Assay Products:

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Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for ZCCHC4
Cloud-Clone Corp. CLIAs for ZCCHC4
Search eBioscience for ELISAs for ZCCHC4 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ZCCHC: Zinc fingers, CCHC domain containing

5 InterPro protein domains:
 IPR001594 Znf_DHHC_palmitoyltrfase
 IPR002052 DNA_methylase_N6_adenine_CS
 IPR010666 Znf_GRF
 IPR019369 N6_adenine_Mtase-rel_euk
 IPR001878 Znf_CCHC

Graphical View of Domain Structure for InterPro Entry Q9H5U6

ProtoNet protein and cluster: Q9H5U6

4 Blocks protein domains:
IPB001594 Zn-finger
IPB001878 C2HC-type zinc-finger signature
IPB002052 N-6 Adenine-specific DNA methylase
IPB010666 GRF zinc finger


UniProtKB/Swiss-Prot: ZCHC4_HUMAN, Q9H5U6
Similarity: Contains 1 CCHC-type zinc finger
Similarity: Contains 1 DHHC-type zinc finger


Find genes that share domains with ZCCHC4           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ZCHC4_HUMAN, Q9H5U6
Function: May be a methyltransferase

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding IEA--
GO:0008168methyltransferase activity IEA--
GO:0008270zinc ion binding IEA--
     
Find genes that share ontologies with ZCCHC4           About GenesLikeMe


Phenotypes:
     1 MGI phenotypic allele for Zcchc4 (no phenotypes)

Find genes that share phenotypes with ZCCHC4           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZCCHC4
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZCCHC4

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZCCHC4
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZCCHC4

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat ZCCHC4 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ZCCHC4 (see all 18):
hsa-miR-30c hsa-miR-579 hsa-miR-644 hsa-miR-520d-5p hsa-miR-30d hsa-miR-30a hsa-miR-199b-5p hsa-miR-186
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for ZCCHC4
Predesigned siRNA for gene silencing in human, mouse, rat ZCCHC4

Gene Editing
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DNA2.0 Custom Protein Engineering Service for ZCCHC4

Clone
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OriGene clones in human, mouse for ZCCHC4 (see all 7)
OriGene ORF clones in mouse, rat for ZCCHC4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ZCCHC4 (NM_024936)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZCCHC4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC4

Cell Line
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Browse ESI BIO Cell Lines and PureStem Progenitors for ZCCHC4 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC4


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2
peroxisome1
plasma membrane1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZCCHC4
Interactions:

    Search GeneGlobe Interaction Network for ZCCHC4

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ZCCHC4 (ZCHC4)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for ZCCHC4 gene: 
NM_024936.2  

Unigene Cluster for ZCCHC4:

Zinc finger, CCHC domain containing 4
Hs.278945  [show with all ESTs]
Unigene Representative Sequence: NM_024936
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000505451(uc003grm.1) ENST00000302874(uc003grl.4) ENST00000507760
ENST00000505412 ENST00000508058
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ZCCHC4 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate ZCCHC4 (see all 18):
hsa-miR-30c hsa-miR-579 hsa-miR-644 hsa-miR-520d-5p hsa-miR-30d hsa-miR-30a hsa-miR-199b-5p hsa-miR-186
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ZCCHC4
Predesigned siRNA for gene silencing in human, mouse, rat ZCCHC4
Clone
Products:
     
OriGene clones in human, mouse for ZCCHC4 (see all 7)
OriGene ORF clones in mouse, rat for ZCCHC4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ZCCHC4 (NM_024936)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZCCHC4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC4
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for ZCCHC4
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZCCHC4
  QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC4
  QuantiFast Probe-based Assays in human, mouse, rat ZCCHC4

Additional mRNA sequence: 

AF161537.1 AK026677.1 AK299211.1 AK309675.1 AY629351.1 BC016914.1 BC157834.1 BC171821.1 

7 DOTS entries:

DT.70103592  DT.40113534  DT.100777767  DT.75126464  DT.100777766  DT.100647803  DT.91811566 

Selected AceView cDNA sequences (see all 47):

AA746804 AW089587 CR610354 AL515869 AK026677 R86073 CR619058 AI698232 
AI092149 BC016914 AA460866 BX348886 AI886021 AW663095 BG724137 BU601731 
BQ228967 BG719159 BX375764 BG168986 AL515868 BG779772 BX503765 AW613723 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC4    About this scheme

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b
SP1:                                                                                                            
SP2:                                -     -     -     -                                                         
SP3:                                                                                                            
SP4:                                                                                      -     -               
SP5:                                                                                            -               


ECgene alternative splicing isoforms for ZCCHC4

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZCCHC4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGCCACCTCA
ZCCHC4 Expression
About this image

ZCCHC4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ZCCHC4 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.278945
    Custom PCR Arrays for ZCCHC4
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for ZCCHC4
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZCCHC4
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QuantiFast Probe-based Assays in human, mouse, rat ZCCHC4
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC4

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for ZCCHC4 gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Zcchc41 , 5 zinc finger, CCHC domain containing 41, 5 82.52(n)1
81.66(a)1
  5 (28.70 cM)5
787961  NM_030185.21  NP_084461.11 
 527754095 
chicken
(Gallus gallus)
Aves ZCCHC41 zinc finger, CCHC domain containing 4 67.28(n)
65.04(a)
  422806  XM_420756.4  XP_420756.3 
lizard
(Anolis carolinensis)
Reptilia ZCCHC46
zinc finger, CCHC domain containing 4
69(a)
1 ↔ 1
GL343348.1(174532-193446)
tropical clawed frog
(Xenopus tropicalis)
Amphibia zcchc41 zinc finger, CCHC domain containing 4 64.45(n)
65.35(a)
  493496  NM_001008133.1  NP_001008134.1 
zebrafish
(Danio rerio)
Actinopterygii zgc:1722481 zgc:172248 60.94(n)
58.8(a)
  564410  NM_001113599.1  NP_001107071.1 
fruit fly
(Drosophila melanogaster)
Insecta CG128631 CG12863 49.08(n)
39.58(a)
  36623  NM_137129.3  NP_610973.3 
worm
(Caenorhabditis elegans)
Secernentea F33A8.41 F33A8.4 45.91(n)
33.51(a)
  174691  NM_063967.4  NP_496368.1 


ENSEMBL Gene Tree for ZCCHC4 (if available)
TreeFam Gene Tree for ZCCHC4 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ZCCHC4 (see all 1220)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 4 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs355654361,2
C,F--25312397(+) CACTTG/ACAAAT 1 -- us2k17Minor allele frequency- A:0.05NA WA EA 366
rs1834297401,2
--25312408(+) TTTATA/GAACAA 1 -- us2k10--------
rs1434502671,2
--25312415(+) ACAAGA/TCTTTT 1 -- us2k10--------
rs1874765531,2
--25312518(+) GCCTAC/GGGCAC 1 -- us2k10--------
rs37562051,2
C,F,H--25312615(-) gagatA/Cggaaa 1 -- us2k127Minor allele frequency- C:0.30NS EA NA CSA WA 2912
rs37562041,2
C,F,H--25312670(+) TGGACA/TACTTG 1 -- us2k124Minor allele frequency- T:0.09EA NA NS 3868
rs1916187061,2
--25312756(+) GAAATA/GTGAAA 1 -- us2k10--------
rs1395573291,2
C--25312767(+) AAAAA-/AA    
   AAAAC
CAGCC
1 -- us2k10--------
rs99909831,2
C,F,H--25312834(+) ccccaA/Gtggtt 1 -- us2k14Minor allele frequency- G:0.00NS EA 418
rs46975631,2
C,F,H--25313117(+) tatgtC/Tgagtc 1 -- us2k110Minor allele frequency- T:0.22NA WA CSA EA 371

HapMap Linkage Disequilibrium report for ZCCHC4 (25314396 - 25372005 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ZCCHC4: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ZCCHC4
DNA2.0 Custom Variant and Variant Library Synthesis for ZCCHC4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611792    OMIM disorders: --


Find genes that share disorders with ZCCHC4           About GenesLikeMe


Export disorders for ZCCHC4 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ZCCHC4 gene integrated from 10 sources:
(articles sorted by number of sources associating them with ZCCHC4)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. (PubMed id 15225602)1, 2 Albrecht M. and Lengauer T. (FEBS Lett. 2004)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (Cell 2006)
  6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  7. (PubMed id )2 

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29063 HGNC: 22917 AceView: ZCCHC4 Ensembl:ENSG00000168228 euGenes: HUgn29063
ECgene: ZCCHC4 H-InvDB: ZCCHC4

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ZCCHC4 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ZCCHC4 gene:
Search GeneIP for patents involving ZCCHC4

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZCCHC4  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ZCCHC4  
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 OriGene qSTAR qPCR primer pairs in human, mouse for ZCCHC4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for ZCCHC4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for ZCCHC4   OriGene Custom Protein Services for ZCCHC4  

 
 
 Block miRNA regulation of human, mouse, rat ZCCHC4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZCCHC4
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZCCHC4 Predesigned siRNA for gene silencing in human, mouse, rat ZCCHC4
 QuantiFast Probe-based Assays in human, mouse, rat ZCCHC4 QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC4
 Custom PCR Arrays for ZCCHC4 Search Chromatin IP Primers for ZCCHC4
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZCCHC4  Search GeneGlobe Interaction Network for ZCCHC4
 Regulatory tfbs in ZCCHC4 promoter
 GenScript Custom Purified and Recombinant Proteins Services for ZCCHC4 GenScript cDNA clones with any tag delivered in your preferred vector for ZCCHC4
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 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for ZCCHC4 (ZCHC4)
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 ZCCHC4 antibodies
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 ZCCHC4 lysates
 Antibodies for ZCCHC4
 See all of Abcam's Antibodies, Kits and Proteins for ZCCHC4
 Custom Antibody / Protein Production Service
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for ZCCHC4
 Antibodies for ZCCHC4
 ELISAs for ZCCHC4
 CLIAs for ZCCHC4



 Browse ESI BIO Cell Lines and PureStem Progenitors for ZCCHC4
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC4
 Browse SwitchGear 3'UTR luciferase reporter plasmids for ZCCHC4
 Browse SwitchGear Promoter luciferase reporter plasmids for ZCCHC4
 ThermoFisher Antibody for ZCCHC4
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC4
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZCCHC4
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZCCHC4
 LSBio Antibodies in human, mouse, rat for ZCCHC4
Customized transgenic rodents for:
 Humanization
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 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for ZCCHC4
  Search eBioscience for proteins for ZCCHC4
  Search eBioscience for elisas for ZCCHC4
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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