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Aliases for ZCCHC18 Gene

Aliases for ZCCHC18 Gene

  • Zinc Finger CCHC-Type Containing 18 2 3
  • Zinc Finger, CCHC Domain Containing 12 Pseudogene 1 2 3
  • Paraneoplastic Ma Antigen Family Member 7B 2 3
  • Putative Zinc Finger CCHC Domain-Containing Protein 18 3
  • Zinc Finger, CCHC Domain Containing 18 5
  • PNMA7B 3
  • SIZN2 3

External Ids for ZCCHC18 Gene

Previous GeneCards Identifiers for ZCCHC18 Gene

  • GC0XP103244
  • GC0XP103356

Summaries for ZCCHC18 Gene

GeneCards Summary for ZCCHC18 Gene

ZCCHC18 (Zinc Finger CCHC-Type Containing 18) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZCCHC12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC18 Gene

Genomics for ZCCHC18 Gene

Regulatory Elements for ZCCHC18 Gene

Enhancers for ZCCHC18 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZCCHC18 on UCSC Golden Path with GeneCards custom track

Promoters for ZCCHC18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZCCHC18 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZCCHC18 Gene

104,112,131 bp from pter
104,115,847 bp from pter
3,717 bases
Plus strand

Genomic View for ZCCHC18 Gene

Genes around ZCCHC18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZCCHC18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZCCHC18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC18 Gene

Proteins for ZCCHC18 Gene

  • Protein details for ZCCHC18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger CCHC domain-containing protein 18
    Protein Accession:

    Protein attributes for ZCCHC18 Gene

    403 amino acids
    Molecular mass:
    45160 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZCCHC18 Gene

Proteomics data for ZCCHC18 Gene at MOPED

Post-translational modifications for ZCCHC18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC18 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZCCHC18 Gene

Domains & Families for ZCCHC18 Gene

Gene Families for ZCCHC18 Gene

Protein Domains for ZCCHC18 Gene


Suggested Antigen Peptide Sequences for ZCCHC18 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ZCCHC12 family.
  • Contains 1 CCHC-type zinc finger.
  • Belongs to the ZCCHC12 family.
  • Contains 1 CCHC-type zinc finger.
genes like me logo Genes that share domains with ZCCHC18: view

Function for ZCCHC18 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity IBA --
genes like me logo Genes that share ontologies with ZCCHC18: view

Animal Model Products

CRISPR Products

miRNA for ZCCHC18 Gene

miRTarBase miRNAs that target ZCCHC18

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZCCHC18 Gene

Localization for ZCCHC18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZCCHC18 Gene

Pathways & Interactions for ZCCHC18 Gene

SuperPathways for ZCCHC18 Gene

No Data Available

Interacting Proteins for ZCCHC18 Gene

Gene Ontology (GO) - Biological Process for ZCCHC18 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZCCHC18 Gene

Drugs & Compounds for ZCCHC18 Gene

No Compound Related Data Available

Transcripts for ZCCHC18 Gene

mRNA/cDNA for ZCCHC18 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZCCHC18 Gene

Zinc finger, CCHC domain containing 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC18 Gene

No ASD Table

Relevant External Links for ZCCHC18 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZCCHC18 Gene

mRNA expression in normal human tissues for ZCCHC18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZCCHC18 Gene Hs.648338

genes like me logo Genes that share expression patterns with ZCCHC18: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZCCHC18 Gene

Orthologs for ZCCHC18 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZCCHC18 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZCCHC18 35
  • 86.18 (n)
  • 80.05 (a)
(Canis familiaris)
Mammalia LOC492040 35
  • 84.94 (n)
  • 80.2 (a)
(Mus musculus)
Mammalia Zcchc18 35
  • 78.09 (n)
  • 68.54 (a)
Zcchc18 16
Zcchc12 36
  • 72 (a)
Zcchc18 36
  • 68 (a)
(Pan troglodytes)
Mammalia ZCCHC18 35
  • 99.5 (n)
  • 98.76 (a)
(Rattus norvegicus)
Mammalia Zcchc18 35
  • 80.43 (n)
  • 71.25 (a)
Species with no ortholog for ZCCHC18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZCCHC18 Gene

Gene Tree for ZCCHC18 (if available)
Gene Tree for ZCCHC18 (if available)

Paralogs for ZCCHC18 Gene

(3) SIMAP similar genes for ZCCHC18 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZCCHC18: view

Variants for ZCCHC18 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZCCHC18 Gene

Variant ID Type Subtype PubMed ID
dgv2459e1 CNV Complex 17122850
nsv469772 CNV Complex 16826518
nsv519626 CNV Gain 19592680
nsv7453 OTHER Inversion 18451855

Variation tolerance for ZCCHC18 Gene

Residual Variation Intolerance Score: 78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.50; 55.31% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for ZCCHC18 Gene

Disorders for ZCCHC18 Gene

Relevant External Links for ZCCHC18

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZCCHC18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC18 Gene

Publications for ZCCHC18 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Identification of proteins that interact with murine cytomegalovirus early protein M112-113 in brain. (PMID: 22340173) Wang H. … Fang F. (Chin. Med. J. 2011) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for ZCCHC18 Gene

Sources for ZCCHC18 Gene