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Aliases for ZCCHC17 Gene

Aliases for ZCCHC17 Gene

  • Zinc Finger, CCHC Domain Containing 17 2 3
  • Zinc Finger CCHC Domain-Containing Protein 17 3 4
  • Putative S1 RNA-Binding Domain Protein 3 4
  • Pnn-Interacting Nucleolar Protein 3 4
  • PNO40 3 4
  • PS1D 3 4
  • Putative S1 RNA Binding Domain Protein 3
  • Nucleolar Protein Of 40 KDa 3
  • Nucleolar Protein 40 3
  • PS1D Protein 4
  • HSPC251 3

External Ids for ZCCHC17 Gene

Previous GeneCards Identifiers for ZCCHC17 Gene

  • GC01P031439
  • GC01P031542
  • GC01P031769
  • GC01P029876

Summaries for ZCCHC17 Gene

GeneCards Summary for ZCCHC17 Gene

ZCCHC17 (Zinc Finger, CCHC Domain Containing 17) is a Protein Coding gene. GO annotations related to this gene include RNA binding.

Gene Wiki entry for ZCCHC17 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC17 Gene

Genomics for ZCCHC17 Gene

Regulatory Elements for ZCCHC17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZCCHC17 Gene

31,296,982 bp from pter
31,365,722 bp from pter
68,741 bases
Plus strand

Genomic View for ZCCHC17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZCCHC17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC17 Gene

Proteins for ZCCHC17 Gene

  • Protein details for ZCCHC17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nucleolar protein of 40 kDa
    Protein Accession:
    Secondary Accessions:
    • B4DY38
    • D3DPN4
    • Q6PKH4
    • Q9NYG4
    • Q9P0M8

    Protein attributes for ZCCHC17 Gene

    241 amino acids
    Molecular mass:
    27570 Da
    Quaternary structure:
    • Interacts with PNN. Associates with the 60S ribosomal subunit (By similarity).
    • Sequence=AAF36171.1; Type=Frameshift; Positions=48; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZCCHC17 Gene

    Alternative splice isoforms for ZCCHC17 Gene


neXtProt entry for ZCCHC17 Gene

Proteomics data for ZCCHC17 Gene at MOPED

Post-translational modifications for ZCCHC17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZCCHC17 Gene

Domains for ZCCHC17 Gene

Gene Families for ZCCHC17 Gene

Protein Domains for ZCCHC17 Gene

Suggested Antigen Peptide Sequences for ZCCHC17 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 S1 motif domain.
  • Contains 1 CCHC-type zinc finger.
  • Contains 1 S1 motif domain.
  • Contains 1 CCHC-type zinc finger.
genes like me logo Genes that share domains with ZCCHC17: view

Function for ZCCHC17 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0005515 protein binding IPI 16189514
GO:0008270 zinc ion binding IEA --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with ZCCHC17: view

Phenotypes for ZCCHC17 Gene

GenomeRNAi human phenotypes for ZCCHC17:
genes like me logo Genes that share phenotypes with ZCCHC17: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZCCHC17

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZCCHC17 Gene

Localization for ZCCHC17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZCCHC17 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for ZCCHC17 Gene COMPARTMENTS Subcellular localization image for ZCCHC17 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZCCHC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IEA --
GO:0022625 cytosolic large ribosomal subunit --
GO:0030529 ribonucleoprotein complex IEA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with ZCCHC17: view

Pathways for ZCCHC17 Gene

SuperPathways for ZCCHC17 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZCCHC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
GO:0098779 activation of mitophagy in response to mitochondrial depolarization IMP 22020285
genes like me logo Genes that share ontologies with ZCCHC17: view

No data available for Pathways by source for ZCCHC17 Gene

Transcripts for ZCCHC17 Gene

Unigene Clusters for ZCCHC17 Gene

Zinc finger, CCHC domain containing 17:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZCCHC17

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC17 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1: - - -
SP2: - -
SP4: -
SP5: -

Relevant External Links for ZCCHC17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZCCHC17 Gene

mRNA expression in normal human tissues for ZCCHC17 Gene

Protein differential expression in normal tissues for ZCCHC17 Gene

This gene is overexpressed in Testis (14.7), Lung (13.9), Retina (11.7), and Pancreatic juice (7.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZCCHC17 Gene

SOURCE GeneReport for Unigene cluster for ZCCHC17 Gene Hs.524094

genes like me logo Genes that share expressions with ZCCHC17: view

Expression partners for ZCCHC17 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZCCHC17 Gene

Orthologs for ZCCHC17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZCCHC17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZCCHC17 35
  • 94.74 (n)
  • 99.17 (a)
-- 36
  • 95 (a)
ZCCHC17 36
  • 99 (a)
(Canis familiaris)
Mammalia ZCCHC17 35
  • 94.05 (n)
  • 99.59 (a)
ZCCHC17 36
  • 97 (a)
(Mus musculus)
Mammalia Zcchc17 35
  • 90.58 (n)
  • 95.07 (a)
Zcchc17 16
Zcchc17 36
  • 95 (a)
(Pan troglodytes)
Mammalia ZCCHC17 35
  • 99.59 (n)
  • 100 (a)
ZCCHC17 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zcchc17 35
  • 89.84 (n)
  • 94.62 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 75 (a)
-- 36
  • 71 (a)
-- 36
  • 73 (a)
(Gallus gallus)
Aves ZCCHC17 36
  • 74 (a)
(Anolis carolinensis)
Reptilia ZCCHC17 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7227 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.34048 35
(Danio rerio)
Actinopterygii zgc65790 35
zcchc17 36
  • 59 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10823 35
Species with no ortholog for ZCCHC17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZCCHC17 Gene

Gene Tree for ZCCHC17 (if available)
Gene Tree for ZCCHC17 (if available)

Paralogs for ZCCHC17 Gene Pseudogenes for ZCCHC17 Gene

genes like me logo Genes that share paralogs with ZCCHC17: view

No data available for Paralogs for ZCCHC17 Gene

Variants for ZCCHC17 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC17 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs11436 -- 31,364,473(+) GGAGG(C/T)CCTAT utr-variant-3-prime
rs756233 -- 31,326,929(-) TCAGA(C/T)CAGAG intron-variant
rs756352 -- 31,327,021(-) CAGTG(G/T)TGGCT intron-variant
rs1566961 -- 31,299,603(-) GGGAG(C/T)TATTG intron-variant
rs1566962 -- 31,299,388(-) ACCCA(A/G)AAAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZCCHC17 Gene

Variant ID Type Subtype PubMed ID
dgv46e1 CNV Complex 17122850
esv1665695 CNV Insertion 17803354

Relevant External Links for ZCCHC17 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZCCHC17 Gene

Disorders for ZCCHC17 Gene

No disorders were found for ZCCHC17 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZCCHC17 Gene

Publications for ZCCHC17 Gene

  1. Molecular characterization of a novel nucleolar protein, pNO40. (PMID: 12893261) Chang W.-L. … Ouyang P. (Biochem. Biophys. Res. Commun. 2003) 2 3 4 23
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 3 4
  3. Identification of ribosomal proteins specific to higher eukaryotic organisms. (PMID: 12202495) Gueydan C. … Kruys V. (J. Biol. Chem. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for ZCCHC17 Gene

Sources for ZCCHC17 Gene

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