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Aliases for ZCCHC17 Gene

Aliases for ZCCHC17 Gene

  • Zinc Finger CCHC-Type Containing 17 2 3 5
  • Zinc Finger CCHC Domain-Containing Protein 17 3 4
  • Pnn-Interacting Nucleolar Protein 3 4
  • PNO40 3 4
  • PS1D 3 4
  • Putative S1 RNA Binding Domain Protein 3
  • Zinc Finger, CCHC Domain Containing 17 3
  • Putative S1 RNA-Binding Domain Protein 4
  • Nucleolar Protein Of 40 KDa 3
  • Nucleolar Protein 40 3
  • PS1D Protein 4
  • HSPC251 3

External Ids for ZCCHC17 Gene

Previous GeneCards Identifiers for ZCCHC17 Gene

  • GC01P031439
  • GC01P031542
  • GC01P031769
  • GC01P029876

Summaries for ZCCHC17 Gene

GeneCards Summary for ZCCHC17 Gene

ZCCHC17 (Zinc Finger CCHC-Type Containing 17) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and poly(A) RNA binding.

Gene Wiki entry for ZCCHC17 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC17 Gene

Genomics for ZCCHC17 Gene

Regulatory Elements for ZCCHC17 Gene

Enhancers for ZCCHC17 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F031687 0.6 Ensembl ENCODE 6.2 +393.1 393120 5.4 ZFP64 SIN3A SCRT2 FOS ZNF680 ZNF654 ZBTB11 REST TBX21 ZNF623 ENSG00000224066 DCDC2B SNRNP40 TSSK3 ENSG00000229447 ADGRB2 IQCC ZCCHC17 COL16A1 GC01M031668
GH01F031570 0.4 ENCODE 4.1 +274.5 274481 1.6 GATA3 ZNF362 ESRRA MTA2 IKZF1 REST TBX21 SERINC2 ZCCHC17 TINAGL1 LOC105378627
GH01F031299 0.7 FANTOM5 0.8 +2.3 2346 0.0 CTCF SUZ12 ZBTB33 EZH2 ZCCHC17 GC01P031311
GH01F031305 0.7 Ensembl ENCODE 0.4 +9.3 9319 2.1 BCOR SMARCA5 CTCF CBX3 JUN BHLHE40 CEBPB ZMYM3 NFXL1 EP300 SERINC2 ENSG00000229044 FABP3 SNRNP40 GC01P031311 ZCCHC17
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZCCHC17 on UCSC Golden Path with GeneCards custom track

Promoters for ZCCHC17 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000669525 -182 2401 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF207 ZNF143

Genomic Location for ZCCHC17 Gene

31,296,982 bp from pter
31,365,722 bp from pter
68,741 bases
Plus strand

Genomic View for ZCCHC17 Gene

Genes around ZCCHC17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZCCHC17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZCCHC17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC17 Gene

Proteins for ZCCHC17 Gene

  • Protein details for ZCCHC17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nucleolar protein of 40 kDa
    Protein Accession:
    Secondary Accessions:
    • B4DY38
    • D3DPN4
    • Q6PKH4
    • Q9NYG4
    • Q9P0M8

    Protein attributes for ZCCHC17 Gene

    241 amino acids
    Molecular mass:
    27570 Da
    Quaternary structure:
    • Interacts with PNN. Associates with the 60S ribosomal subunit (By similarity).
    • Sequence=AAF36171.1; Type=Frameshift; Positions=48; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZCCHC17 Gene

    Alternative splice isoforms for ZCCHC17 Gene


neXtProt entry for ZCCHC17 Gene

Post-translational modifications for ZCCHC17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZCCHC17 Gene

Domains & Families for ZCCHC17 Gene

Gene Families for ZCCHC17 Gene

Protein Domains for ZCCHC17 Gene

Suggested Antigen Peptide Sequences for ZCCHC17 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 S1 motif domain.
  • Contains 1 CCHC-type zinc finger.
  • Contains 1 S1 motif domain.
  • Contains 1 CCHC-type zinc finger.
genes like me logo Genes that share domains with ZCCHC17: view

Function for ZCCHC17 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0008270 zinc ion binding IEA --
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZCCHC17: view
genes like me logo Genes that share phenotypes with ZCCHC17: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZCCHC17 Gene

Localization for ZCCHC17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZCCHC17 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for ZCCHC17 Gene COMPARTMENTS Subcellular localization image for ZCCHC17 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZCCHC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IEA --
GO:0022625 cytosolic large ribosomal subunit IEA --
GO:0030529 intracellular ribonucleoprotein complex IEA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with ZCCHC17: view

Pathways & Interactions for ZCCHC17 Gene

SuperPathways for ZCCHC17 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZCCHC17 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZCCHC17 Gene

Transcripts for ZCCHC17 Gene

Unigene Clusters for ZCCHC17 Gene

Zinc finger, CCHC domain containing 17:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC17 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1: - - -
SP2: - -
SP4: -
SP5: -

Relevant External Links for ZCCHC17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZCCHC17 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZCCHC17 Gene

Protein differential expression in normal tissues from HIPED for ZCCHC17 Gene

This gene is overexpressed in Testis (14.7), Lung (13.9), Retina (11.7), and Pancreatic juice (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZCCHC17 Gene

Protein tissue co-expression partners for ZCCHC17 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZCCHC17 Gene:


SOURCE GeneReport for Unigene cluster for ZCCHC17 Gene:

genes like me logo Genes that share expression patterns with ZCCHC17: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZCCHC17 Gene

Orthologs for ZCCHC17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZCCHC17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZCCHC17 34 35
  • 99.59 (n)
(Bos Taurus)
Mammalia -- 35
  • 95 (a)
ZCCHC17 34 35
  • 94.74 (n)
(Canis familiaris)
Mammalia ZCCHC17 34 35
  • 94.05 (n)
(Mus musculus)
Mammalia Zcchc17 34 16 35
  • 90.58 (n)
(Rattus norvegicus)
Mammalia Zcchc17 34
  • 89.84 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 75 (a)
-- 35
  • 73 (a)
-- 35
  • 71 (a)
(Gallus gallus)
Aves ZCCHC17 35
  • 74 (a)
(Anolis carolinensis)
Reptilia ZCCHC17 35
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7227 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.34048 34
(Danio rerio)
Actinopterygii zcchc17 35
  • 59 (a)
zgc65790 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10823 34
Species where no ortholog for ZCCHC17 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZCCHC17 Gene

Gene Tree for ZCCHC17 (if available)
Gene Tree for ZCCHC17 (if available)

Paralogs for ZCCHC17 Gene Pseudogenes for ZCCHC17 Gene

genes like me logo Genes that share paralogs with ZCCHC17: view

No data available for Paralogs for ZCCHC17 Gene

Variants for ZCCHC17 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC17 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs431905488 untested 31,365,958(-) ATCTC(A/G)CTCTG intron-variant, downstream-variant-500B
rs483352865 untested 31,365,893(-) GAAAG(-/A)GGCAT intron-variant, downstream-variant-500B, reference, frameshift-variant
rs483352875 untested 31,365,952(-) ACTCT(-/GT)CTTTC intron-variant, downstream-variant-500B
rs1048168 -- 31,365,901(-) ACTTA(C/T)GAGAA intron-variant, downstream-variant-500B, reference, synonymous-codon
rs10564200 -- 31,323,979(+) ATGAC(-/TG)TATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZCCHC17 Gene

Variant ID Type Subtype PubMed ID
esv1665695 CNV insertion 17803354
esv2758930 CNV loss 17122850
esv3585647 CNV loss 21293372
esv3585648 CNV loss 21293372

Variation tolerance for ZCCHC17 Gene

Residual Variation Intolerance Score: 33.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.50; 10.89% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZCCHC17 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZCCHC17 Gene

Disorders for ZCCHC17 Gene

Relevant External Links for ZCCHC17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZCCHC17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC17 Gene

Publications for ZCCHC17 Gene

  1. Molecular characterization of a novel nucleolar protein, pNO40. (PMID: 12893261) Chang W.-L. … Ouyang P. (Biochem. Biophys. Res. Commun. 2003) 2 3 4 22 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Identification of ribosomal proteins specific to higher eukaryotic organisms. (PMID: 12202495) Gueydan C. … Kruys V. (J. Biol. Chem. 2002) 2 3 64

Products for ZCCHC17 Gene

Sources for ZCCHC17 Gene

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