ZCCHC16 Gene
protein-coding GIFtS: 38
GCID: GC0XP111326
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zinc finger, CCHC domain containing 16
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Aliases
for ZCCHC16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, CCHC Domain Containing 161 2 | | FLJ466081 | | Mar41 2 | | Zinc Finger CCHC Domain-Containing Protein 162 | | Mart41 2 | | MAR33 | | Mammalian Retrotransposon-Derived Protein 42 3 | | MART43 |
Export aliases for ZCCHC16 gene to outside databasesPrevious GC identifers: GC0XP111133 GC0XP101307 |
Summaries
for ZCCHC16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZCCHC16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZCCHC16 gene promoter:
Sp1 RREB-1 NF-YA HNF-3beta NF-YB CBF-A CBF-B CP1A NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZCCHC16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZCCHC16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq23 Ensembl cytogenetic band: Xq23 HGNC cytogenetic band: Xq23ZCCHC16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP111326: view genomic region
(about GC identifiers)
Start:
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111,326,253 bp from pter |
End:
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111,700,473 bp from pter |
Size:
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374,221 bases |
Orientation:
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plus strand |
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Proteins
for ZCCHC16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZCH16_HUMAN, Q6ZR62 (See
protein sequence)Recommended Name: Zinc finger CCHC domain-containing protein 16 Size: 310 amino acids; 34685 Da
Secondary accessions: B2RPG1Explore the universe of human proteins at neXtProt for ZCCHC16: NX_Q6ZR62
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZR62
ZCCHC16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001004308.2
ENSEMBL proteins: ENSP00000340590
Human Recombinant Protein Products:
ZCCHC16 Antibody Products:
Assay Products for ZCCHC16: |
Protein
Domains /
Families
for ZCCHC16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZCCHC16 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6ZR62ProtoNet protein and cluster: Q6ZR62 1 Blocks protein family: IPB001878 C2HC-type zinc-finger signature
UniProtKB/Swiss-Prot: ZCH16_HUMAN, Q6ZR62Similarity: Contains 1 CCHC-type zinc finger |
Function
for ZCCHC16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZCCHC16 (NM_001004308) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZCCHC16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC16 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZCCHC16 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZCCHC16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZCCHC16
|
Drugs & Compounds
for ZCCHC16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZCCHC16
Search CenterWatch for drugs/clinical trials and news about ZCCHC16 / ZCH16
|
Transcripts
for ZCCHC16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZCCHC16 gene: NM_001004308.2 Unigene Cluster for ZCCHC16: Zinc finger, CCHC domain containing 16 Hs.368140 Unigene Representative Sequence: NM_0010043081 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000340433(uc022cct.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZCCHC16 (NM_001004308) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZCCHC16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC16 |
Additional cDNA sequence: AK128465.1 BC137430.1 BC137433.1 1 DOTS entry: DT.101974423 2 AceView cDNA sequences: NM_001004308 AK128465
GeneLoc Exon Structure
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Expression
for ZCCHC16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZCCHC16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATCCCATT
About this image
See ZCCHC16 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.368140
SABiosciences Custom PCR Arrays for ZCCHC16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZCCHC16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZCCHC16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZCCHC16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC16 |
Orthologs
for ZCCHC16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZCCHC16 gene from 2/5 species (see all 5) About this table
ENSEMBL Gene Tree for ZCCHC16 (if available)
TreeFam Gene Tree for ZCCHC16 (if available) |
Paralogs
for ZCCHC16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZCCHC16 gene
- PEG102 ZCCHC52
ZCCHC16 for paralogs About GeneDecksing
|
Genomic Variants
for ZCCHC16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZCCHC16 (111326253 - 111576253 bp, first 250kb of ZCCHC16)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZCCHC16
2 CNVs: 52905 36985 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZCCHC16 |
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Disorders
/ Diseases
for ZCCHC16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZCCHC16 for disorders About MalaCards
ZCCHC16 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZCCHC16 (1 document)
Export disorders for ZCCHC16 gene to outside databases
|
Publications
for ZCCHC16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZCCHC16 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZCCHC16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. (PubMed id 16093683)1, 3 Brandt J....Volff J.N. (2005)
- Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. (PubMed id 15716091)1, 3 Brandt J.... Volff J.-N. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome-wide association study of biochemical traits in Korcula Island, Croatia. (PubMed id 19260141)1 Zemunik T....Rudan I. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZCCHC16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZCCHC16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZCCHC16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZCCHC16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZCCHC16 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZCCHC16 gene:
Search GeneIP for patents involving ZCCHC16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZCCHC16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZCCHC16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZCCHC16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZCCHC16 | | | OriGene Protein Over-expression Lysate for ZCCHC16 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZCCHC16 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZCCHC16 | | OriGene Custom Protein Services for ZCCHC16 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZCCHC16 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZCCHC16 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZCCHC16 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZCCHC16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZCCHC16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC16 |
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| | | | Search Tocris compounds for ZCCHC16 |
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 | | | ZCCHC16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC16 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZCCHC16 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC16 |
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