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Aliases for ZCCHC13 Gene

Aliases for ZCCHC13 Gene

  • Zinc Finger CCHC-Type Containing 13 2 3 5
  • Zinc Finger CCHC Domain-Containing Protein 13 3
  • Zinc Finger, CCHC Domain Containing 13 3
  • CNBP2 3
  • ZNF9L 3

External Ids for ZCCHC13 Gene

Previous GeneCards Identifiers for ZCCHC13 Gene

  • GC0XP073307
  • GC0XP073440
  • GC0XP073524
  • GC0XP067159

Summaries for ZCCHC13 Gene

Entrez Gene Summary for ZCCHC13 Gene

  • This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 3. However, the CDS of this intronless gene remains relatively intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. The encoded protein contains six CCHC-type zinc fingers, and is thus thought to function as a transcription factor. [provided by RefSeq, May 2010]

GeneCards Summary for ZCCHC13 Gene

ZCCHC13 (Zinc Finger CCHC-Type Containing 13) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is CNBP.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC13 Gene

Genomics for ZCCHC13 Gene

Regulatory Elements for ZCCHC13 Gene

Enhancers for ZCCHC13 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF074342 1.3 Ensembl ENCODE 29 +39.5 39456 1.9 HDGF WRNIP1 GLI4 FEZF1 ZNF2 ETS1 YY1 ZNF121 ZNF207 KLF7 ZCCHC13 FTX ENSG00000271533 ENSG00000226515 LOC727681
GH0XF074534 1.4 FANTOM5 Ensembl ENCODE 16.2 +231.9 231893 3.8 PKNOX1 ZNF133 FEZF1 RAD21 GLIS2 SCRT2 EGR2 ZNF263 ZNF654 SP3 ZCCHC13 SLC16A2 RLIM PIR45746 PIR50185
GH0XF073943 1.2 ENCODE 16.2 -359.7 -359651 2.2 MLX YBX1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 RAB11FIP1P1 ENSG00000271430 JPX FTX DDX3P1 ENSG00000271199 RN7SL648P TOMM20P4 ENSG00000228906 ENSG00000271533
GH0XF073850 1.1 ENCODE 16.2 -452.5 -452516 2.3 PKNOX1 CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF302 ZNF548 FOS ZNF263 RAB11FIP1P1 JPX ENSG00000271430 RN7SL648P TOMM20P4 FTX ZCCHC13 ENSG00000271533 ENSG00000234969 ENSG00000271199
GH0XF073562 1 ENCODE 16.2 -740.8 -740810 2.5 HDGF GLI4 ZNF2 YY1 ZNF207 ZNF263 SP3 YY2 ZHX2 SREBF1 ENSG00000225396 LOC100132304 ZCCHC13 JPX RAB11FIP1P1 CHIC1 PIR39676
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZCCHC13 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZCCHC13 Gene

74,304,190 bp from pter
74,305,034 bp from pter
845 bases
Plus strand

Genomic View for ZCCHC13 Gene

Genes around ZCCHC13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZCCHC13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZCCHC13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC13 Gene

Proteins for ZCCHC13 Gene

  • Protein details for ZCCHC13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger CCHC domain-containing protein 13
    Protein Accession:

    Protein attributes for ZCCHC13 Gene

    166 amino acids
    Molecular mass:
    18005 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZCCHC13 Gene

Post-translational modifications for ZCCHC13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC13 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZCCHC13 Gene

Domains & Families for ZCCHC13 Gene

Gene Families for ZCCHC13 Gene

Protein Domains for ZCCHC13 Gene


Suggested Antigen Peptide Sequences for ZCCHC13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 6 CCHC-type zinc fingers.
  • Contains 6 CCHC-type zinc fingers.
genes like me logo Genes that share domains with ZCCHC13: view

Function for ZCCHC13 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZCCHC13: view
genes like me logo Genes that share phenotypes with ZCCHC13: view

Animal Model Products

miRNA for ZCCHC13 Gene

miRTarBase miRNAs that target ZCCHC13

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZCCHC13 Gene

Localization for ZCCHC13 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZCCHC13 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC13 Gene

Pathways & Interactions for ZCCHC13 Gene

SuperPathways for ZCCHC13 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZCCHC13 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZCCHC13 Gene

Transcripts for ZCCHC13 Gene

mRNA/cDNA for ZCCHC13 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZCCHC13 Gene

Zinc finger, CCHC domain containing 13:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC13 Gene

No ASD Table

Relevant External Links for ZCCHC13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZCCHC13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZCCHC13 Gene

mRNA differential expression in normal tissues according to GTEx for ZCCHC13 Gene

This gene is overexpressed in Testis (x52.9).

Protein differential expression in normal tissues from HIPED for ZCCHC13 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZCCHC13 Gene

Protein tissue co-expression partners for ZCCHC13 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZCCHC13 Gene:


SOURCE GeneReport for Unigene cluster for ZCCHC13 Gene:

genes like me logo Genes that share expression patterns with ZCCHC13: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZCCHC13 Gene

Orthologs for ZCCHC13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZCCHC13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZCCHC13 34
  • 99.11 (n)
(Canis familiaris)
Mammalia ZCCHC13 35
  • 77 (a)
(Bos Taurus)
Mammalia ZCCHC13 35
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 59 (a)
(Mus musculus)
Mammalia Zcchc13 35
  • 58 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 48 (a)
(Gallus gallus)
Aves CNBP 35
  • 58 (a)
(Danio rerio)
Actinopterygii cnbpb 35
  • 53 (a)
cnbpa 35
  • 52 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3800 35
  • 30 (a)
(Caenorhabditis elegans)
Secernentea K08D12.3 35
  • 29 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GIS2 35
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10180 35
  • 24 (a)
Species where no ortholog for ZCCHC13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZCCHC13 Gene

Gene Tree for ZCCHC13 (if available)
Gene Tree for ZCCHC13 (if available)

Paralogs for ZCCHC13 Gene

Paralogs for ZCCHC13 Gene

(2) SIMAP similar genes for ZCCHC13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZCCHC13: view

Variants for ZCCHC13 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC13 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs10654348 -- 74,302,304(+) ATGAT(-/AAG)AAGAA upstream-variant-2KB
rs111676408 -- 74,304,748(+) ATCTA(A/G)CCAAG reference, missense
rs112142144 -- 74,304,549(+) CCTGC(A/G)GCAGA reference, missense
rs112576615 -- 74,304,679(+) TGGCC(A/G)CGTGG reference, missense
rs113865303 -- 74,303,794(+) GCTAA(A/T)TTTTG upstream-variant-2KB

Variation tolerance for ZCCHC13 Gene

Residual Variation Intolerance Score: 73.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.83; 47.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZCCHC13 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZCCHC13 Gene

Disorders for ZCCHC13 Gene

Relevant External Links for ZCCHC13

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZCCHC13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC13 Gene

Publications for ZCCHC13 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation. (PMID: 18312684) Titulaer M.K. … Luider T.M. (BMC Bioinformatics 2008) 3 64
  4. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan R.S. … Benjamin E.J. (BMC Med. Genet. 2007) 46 64
  5. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3 64

Products for ZCCHC13 Gene

Sources for ZCCHC13 Gene

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