ZCCHC13 Gene
protein-coding GIFtS: 47
GCID: GC0XP073524
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zinc finger, CCHC domain containing 13
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Aliases
for ZCCHC13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, CCHC Domain Containing 131 2 | | ZNF9L1 2 | | 4930513O09RIK1 | | Cnbp21 | | CNBP22 | | Zinc Finger CCHC Domain-Containing Protein 132 |
Export aliases for ZCCHC13 gene to outside databasesPrevious GC identifers: GC0XP073307 GC0XP073440 GC0XP067159 |
Summaries
for ZCCHC13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZCCHC13:
This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 3. However,the CDS of this intronless gene remains relatively intact, it is conserved in other mammalian species, it is known tobe transcribed, and it is therefore thought to encode a functional protein. The encoded protein contains six CCHC-typezinc fingers, and is thus thought to function as a transcription factor. (provided by RefSeq, May 2010)
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Genomic Views
for ZCCHC13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011669.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZCCHC13 gene promoter:
Spz1 AML1a HSF1 (long) C/EBPalpha Evi-1 AREB6 Max Cart-1 HSF1short c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZCCHC13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZCCHC13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq13.2 Ensembl cytogenetic band: Xq13.2 HGNC cytogenetic band: Xq13.2ZCCHC13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP073524: view genomic region
(about GC identifiers)
Start:
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73,524,025 bp from pter |
End:
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73,524,869 bp from pter |
Size:
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845 bases |
Orientation:
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plus strand |
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Proteins
for ZCCHC13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZCH13_HUMAN, Q8WW36 (See
protein sequence)Recommended Name: Zinc finger CCHC domain-containing protein 13 Size: 166 amino acids; 18005 DaExplore the universe of human proteins at neXtProt for ZCCHC13: NX_Q8WW36
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WW36
ZCCHC13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_976048.1
ENSEMBL proteins: ENSP00000345633
Human Recombinant Protein Products:
ZCCHC13 Antibody Products:
Assay Products for ZCCHC13: |
Protein
Domains /
Families
for ZCCHC13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZCCHC13 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8WW36ProtoNet protein and cluster: Q8WW36 UniProtKB/Swiss-Prot: ZCH13_HUMAN, Q8WW36Similarity: Contains 6 CCHC-type zinc fingers |
Function
for ZCCHC13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC13
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC13 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZCCHC13 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZCCHC13:
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Pathways & Interactions
for ZCCHC13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZCCHC13
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/189 Interacting proteins for ZCCHC13 (Q8WW362, 3 ENSP000003456334) via UniProtKB, MINT, STRING, and/or I2D (see all 189)About this table
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Drugs & Compounds
for ZCCHC13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZCCHC13
Search CenterWatch for drugs/clinical trials and news about ZCCHC13 / ZCH13
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Transcripts
for ZCCHC13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZCCHC13 gene: NM_203303.2 Unigene Cluster for ZCCHC13: Zinc finger, CCHC domain containing 13 Hs.157231 [show with all ESTs]Unigene Representative Sequence: NM_2033031 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000339534(uc004ebs.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC13
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZCCHC13 (NM_203303) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZCCHC13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC13 |
Additional cDNA sequence: BC021176.2 1 DOTS entry: DT.439050 6 AceView cDNA sequences: BC021176 BX109166 BI464391 NM_203303 AA812774 AA834973
GeneLoc Exon Structure
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Expression
for ZCCHC13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZCCHC13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAAAGGAGG
About this image
See ZCCHC13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZCCHC13
SOURCE GeneReport for Unigene cluster: Hs.157231
SABiosciences Custom PCR Arrays for ZCCHC13
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZCCHC13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZCCHC13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZCCHC13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC13 |
Orthologs
for ZCCHC13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZCCHC13 gene from 6/16 species (see all 16) About this table
ENSEMBL Gene Tree for ZCCHC13 (if available)
TreeFam Gene Tree for ZCCHC13 (if available) |
Paralogs
for ZCCHC13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZCCHC13 gene
- CNBP2
2 SIMAP similar genes for ZCCHC13 using alignment to 1 protein entry: ZCH13_HUMAN:ZNF9 CNBP
ZCCHC13 for paralogs About GeneDecksing
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Genomic Variants
for ZCCHC13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZCCHC13 (73524025 - 73524869 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZCCHC13: --
Human Gene Mutation Database (HGMD): ZCCHC13
Locus Specific Mutation Databases (LSDB): ZCCHC13
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZCCHC13 |
|
Disorders
/ Diseases
for ZCCHC13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZCCHC13 for disorders About GeneDecksing
6  diseases for ZCCHC13: About MalaCardsmyotonic dystrophy type 2 myotonic dystrophy x inactivation neurodegeneration
dementia ataxia
Export disorders for ZCCHC13 gene to outside databases
|
Publications
for ZCCHC13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZCCHC13 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZCCHC13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation. (PubMed id 18312684)1 Titulaer M.K....Luider T.M. (2008)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
- Identification of nine human-specific frameshift mutations by comparative analysis of the human and the chimpanzee genome sequences. (PubMed id 15961456)1 Hahn Y. and Lee B. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. (PubMed id 12045143)1 Chureau C....Duret L. (2002)
- Dementias, neurodegeneration, and viral mechanisms of disease from the perspective of human transmissible encephalopathies. (PubMed id 8030947)9 Manuelidis L. (1994)
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External Searches for ZCCHC13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZCCHC13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ZCCHC13 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZCCHC13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZCCHC13 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for ZCCHC13 gene:
Search GeneIP for patents involving ZCCHC13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZCCHC13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
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 | | | ZCCHC13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC13 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC13 |
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