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Aliases for ZCCHC13 Gene

Aliases for ZCCHC13 Gene

  • Zinc Finger, CCHC Domain Containing 13 2 3
  • Zinc Finger CCHC Domain-Containing Protein 13 3
  • CNBP2 3
  • ZNF9L 3

External Ids for ZCCHC13 Gene

Previous GeneCards Identifiers for ZCCHC13 Gene

  • GC0XP073307
  • GC0XP073440
  • GC0XP073524
  • GC0XP067159

Summaries for ZCCHC13 Gene

Entrez Gene Summary for ZCCHC13 Gene

  • This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 3. However, the CDS of this intronless gene remains relatively intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. The encoded protein contains six CCHC-type zinc fingers, and is thus thought to function as a transcription factor. [provided by RefSeq, May 2010]

GeneCards Summary for ZCCHC13 Gene

ZCCHC13 (Zinc Finger, CCHC Domain Containing 13) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is CNBP.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC13 Gene

Genomics for ZCCHC13 Gene

Regulatory Elements for ZCCHC13 Gene

Genomic Location for ZCCHC13 Gene

Start:
74,304,190 bp from pter
End:
74,305,034 bp from pter
Size:
845 bases
Orientation:
Plus strand

Genomic View for ZCCHC13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZCCHC13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZCCHC13 Gene

Proteins for ZCCHC13 Gene

  • Protein details for ZCCHC13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WW36-ZCH13_HUMAN
    Recommended name:
    Zinc finger CCHC domain-containing protein 13
    Protein Accession:
    Q8WW36
    Secondary Accessions:

    Protein attributes for ZCCHC13 Gene

    Size:
    166 amino acids
    Molecular mass:
    18005 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZCCHC13 Gene

Proteomics data for ZCCHC13 Gene at MOPED

Post-translational modifications for ZCCHC13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZCCHC13 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZCCHC13 Gene

Domains for ZCCHC13 Gene

Gene Families for ZCCHC13 Gene

HGNC:
  • ZCCHC :Zinc fingers, CCHC domain containing

Protein Domains for ZCCHC13 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZCCHC13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WW36

UniProtKB/Swiss-Prot:

ZCH13_HUMAN :
  • Q8WW36
Similarity:
  • Contains 6 CCHC-type zinc fingers.
genes like me logo Genes that share domains with ZCCHC13: view

Function for ZCCHC13 Gene

Gene Ontology (GO) - Molecular Function for ZCCHC13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZCCHC13: view

Phenotypes for ZCCHC13 Gene

GenomeRNAi human phenotypes for ZCCHC13:
genes like me logo Genes that share phenotypes with ZCCHC13: view

Animal Model Products

CRISPR Products

miRNA for ZCCHC13 Gene

miRTarBase miRNAs that target ZCCHC13

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZCCHC13

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZCCHC13 Gene

Localization for ZCCHC13 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZCCHC13 Gene COMPARTMENTS Subcellular localization image for ZCCHC13 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC13 Gene

Pathways for ZCCHC13 Gene

SuperPathways for ZCCHC13 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZCCHC13 Gene

None

No data available for Pathways by source for ZCCHC13 Gene

Transcripts for ZCCHC13 Gene

mRNA/cDNA for ZCCHC13 Gene

(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZCCHC13 Gene

Zinc finger, CCHC domain containing 13:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZCCHC13

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC13 Gene

No ASD Table

Relevant External Links for ZCCHC13 Gene

GeneLoc Exon Structure for
ZCCHC13
ECgene alternative splicing isoforms for
ZCCHC13

Expression for ZCCHC13 Gene

mRNA expression in normal human tissues for ZCCHC13 Gene

mRNA differential expression in normal tissues according to GTEx for ZCCHC13 Gene

This gene is overexpressed in Testis (52.9).

Protein differential expression in normal tissues for ZCCHC13 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZCCHC13 Gene

SOURCE GeneReport for Unigene cluster for ZCCHC13 Gene Hs.157231

genes like me logo Genes that share expressions with ZCCHC13: view

Expression partners for ZCCHC13 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZCCHC13 Gene

Orthologs for ZCCHC13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZCCHC13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZCCHC13 35
  • 99.11 (n)
  • 97.33 (a)
cow
(Bos Taurus)
Mammalia ZCCHC13 36
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZCCHC13 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zcchc13 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 59 (a)
OneToMany
chicken
(Gallus gallus)
Aves CNBP 36
  • 58 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii cnbpa 36
  • 52 (a)
ManyToMany
cnbpb 36
  • 53 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG3800 36
  • 30 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea K08D12.3 36
  • 29 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GIS2 36
  • 29 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10180 36
  • 24 (a)
OneToMany
Species with no ortholog for ZCCHC13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZCCHC13 Gene

ENSEMBL:
Gene Tree for ZCCHC13 (if available)
TreeFam:
Gene Tree for ZCCHC13 (if available)

Paralogs for ZCCHC13 Gene

Paralogs for ZCCHC13 Gene

Selected SIMAP similar genes for ZCCHC13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZCCHC13: view

Variants for ZCCHC13 Gene

Sequence variations from dbSNP and Humsavar for ZCCHC13 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs174118 -- 74,303,858(-) cacga(A/G)gtcaa upstream-variant-2KB
rs174119 -- 74,303,500(+) GATAT(G/T)TTTAC upstream-variant-2KB
rs174120 -- 74,302,570(+) tccca(A/G)gttca upstream-variant-2KB
rs5937269 -- 74,302,425(+) aaagc(C/G)taaat upstream-variant-2KB
rs10654348 -- 74,302,304(+) ATGAT(-/AAG)AAGAA upstream-variant-2KB

Relevant External Links for ZCCHC13 Gene

HapMap Linkage Disequilibrium report
ZCCHC13
Human Gene Mutation Database (HGMD)
ZCCHC13
Locus Specific Mutation Databases (LSDB)
ZCCHC13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZCCHC13 Gene

Disorders for ZCCHC13 Gene

Relevant External Links for ZCCHC13

Genetic Association Database (GAD)
ZCCHC13

No disorders were found for ZCCHC13 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZCCHC13 Gene

Publications for ZCCHC13 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Identification of nine human-specific frameshift mutations by comparative analysis of the human and the chimpanzee genome sequences. (PMID: 15961456) Hahn Y. … Lee B. (Bioinformatics 2005) 3
  3. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3
  4. A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation. (PMID: 18312684) Titulaer M.K. … Luider T.M. (BMC Bioinformatics 2008) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZCCHC13 Gene

Sources for ZCCHC13 Gene

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