ZCCHC10 Gene
protein-coding GIFtS: 44
GCID: GC05M132332
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|
zinc finger, CCHC domain containing 10
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Aliases
for ZCCHC10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, CCHC Domain Containing 101 2 | | FLJ200941 | | Zinc Finger CCHC Domain-Containing Protein 102 |
Export aliases for ZCCHC10 gene to outside databasesPrevious GC identifers: GC05M132409 GC05M132360 GC05M127524 |
Summaries
for ZCCHC10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZCCHC10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZCCHC10 gene promoter:
CREB AP-1 ATF-2 deltaCREB c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZCCHC10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZCCHC10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1ZCCHC10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M132332: view genomic region
(about GC identifiers)
Start:
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132,332,677 bp from pter |
End:
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132,362,296 bp from pter |
Size:
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29,620 bases |
Orientation:
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minus strand |
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Proteins
for ZCCHC10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZCH10_HUMAN, Q8TBK6 (See
protein sequence)Recommended Name: Zinc finger CCHC domain-containing protein 10 Size: 192 amino acids; 20967 Da
Secondary accessions: Q9NXR4Alternative splicing: 2 isoforms: Q8TBK6-1 Q8TBK6-2 Explore the universe of human proteins at neXtProt for ZCCHC10: NX_Q8TBK6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TBK6
ZCCHC10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060135.1
ENSEMBL proteins: ENSP00000324274 ENSP00000347533 ENSP00000423276 ENSP00000427430 ENSP00000422111 ENSP00000421071 ENSP00000427359
Human Recombinant Protein Products:
ZCCHC10 Antibody Products:
Assay Products for ZCCHC10: |
Protein
Domains /
Families
for ZCCHC10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZCCHC10 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8TBK6ProtoNet protein and cluster: Q8TBK6 1 Blocks protein family: IPB001878 C2HC-type zinc-finger signature
UniProtKB/Swiss-Prot: ZCH10_HUMAN, Q8TBK6Similarity: Contains 1 CCHC-type zinc finger |
Function
for ZCCHC10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZCCHC10 (NM_017665) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZCCHC10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC10 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZCCHC10 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZCCHC10:
|
Pathways & Interactions
for ZCCHC10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZCCHC10
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/32 Interacting proteins for ZCCHC10 (Q8TBK62, 3 ENSP000003242744) via UniProtKB, MINT, STRING, and/or I2D (see all 32)About this table
|
Drugs & Compounds
for ZCCHC10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZCCHC10
Search CenterWatch for drugs/clinical trials and news about ZCCHC10 / ZCH10
|
Transcripts
for ZCCHC10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZCCHC10 gene: NM_017665.1 Unigene Cluster for ZCCHC10: Zinc finger, CCHC domain containing 10 Hs.29700 [show with all ESTs]Unigene Representative Sequence: AK12297010 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000324170(uc003kyg.3 uc011cxl.2) ENST00000355372(uc003kyh.3)
ENST00000509437 ENST00000513848 ENST00000513541 ENST00000508080 ENST00000509008
ENST00000506403 ENST00000511440 ENST00000504170(uc003kyi.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZCCHC10 (NM_017665) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZCCHC10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC10 |
Additional cDNA sequence: AF086446.1 AK000101.1 AK122970.1 AK300543.1 BC005211.1 BC015986.1 BC022443.1 11 DOTS entries: DT.211270 DT.100786399 DT.100786405 DT.100786407 DT.102828795 DT.100786401 DT.91766522 DT.91766517 DT.100786402 DT.120839787 DT.91952741 24/146 AceView cDNA sequences (see all 146): AK122970 BM835147 BU165290 AI243398 AW663410 BF983215 W79536 NM_017665 AF086446 BX095107 AW663425 AI368938 BU170057 BM800630 AA700745 BC005211 CR598591 AU280137 BC022443 AA862483 AA918827 AK000101 AA708627 AA393762
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ZCCHC10 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b |
|---|
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| SP1: | | | | | | | | | | | - | | | | - | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZCCHC10
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Expression
for ZCCHC10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZCCHC10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAGATGTCA
About this image
See ZCCHC10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZCCHC10
SOURCE GeneReport for Unigene cluster: Hs.29700
SABiosciences Custom PCR Arrays for ZCCHC10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZCCHC10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZCCHC10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZCCHC10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC10 |
Orthologs
for ZCCHC10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZCCHC10 gene from 8/25 species (see all 25) About this table
ENSEMBL Gene Tree for ZCCHC10 (if available)
TreeFam Gene Tree for ZCCHC10 (if available) |
Paralogs
for ZCCHC10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZCCHC10 gene
- RNPS12 PNN2 TPRXL2
11 SIMAP similar genes for ZCCHC10 using alignment to 6 protein entries: ZCH10_HUMAN (see all proteins):LRRC37A3 FAM138D TMEM135 ZNF670 ZNF843 FAM138A
FAM138B FAM138C FAM138F KIAA1651 DNAPTP3
ZCCHC10 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZCCHC10
PGOHUM00000237886 PGOHUM00000251299
|
Genomic Variants
for ZCCHC10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZCCHC10 (132332677 - 132362296 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZCCHC10: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZCCHC10 |
|
Disorders
/ Diseases
for ZCCHC10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZCCHC10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZCCHC10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZCCHC10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
|
External Searches for ZCCHC10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZCCHC10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZCCHC10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZCCHC10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZCCHC10 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZCCHC10 gene:
Search GeneIP for patents involving ZCCHC10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZCCHC10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZCCHC10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZCCHC10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZCCHC10 | | | OriGene Protein Over-expression Lysate for ZCCHC10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZCCHC10 | | OriGene 3'-UTR Clone for ZCCHC10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZCCHC10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZCCHC10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZCCHC10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZCCHC10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZCCHC10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZCCHC10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZCCHC10 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZCCHC10 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZCCHC10 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZCCHC10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZCCHC10 |
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