Aliases for ZCCHC10 Gene
Aliases for ZCCHC10 Gene
External Ids for ZCCHC10 Gene
- HGNC: 25954
- Entrez Gene: 54819
- Ensembl: ENSG00000155329
- UniProtKB: Q8TBK6
Previous GeneCards Identifiers for ZCCHC10 Gene
- GC05M132409
- GC05M132360
- GC05M132332
- GC05M127524
Summaries for ZCCHC10 Gene
GeneCards Summary for ZCCHC10 Gene
ZCCHC10 (Zinc Finger CCHC-Type Containing 10) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC10 Gene
Genomics for ZCCHC10 Gene
Regulatory Elements for ZCCHC10 Gene
Enhancers for ZCCHC10 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around ZCCHC10 on UCSC Golden Path with GeneCards custom track
Promoters for ZCCHC10 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around ZCCHC10 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ZCCHC10 gene promoter:
Regulatory Element Products
Genomic Location for ZCCHC10 Gene
- Chromosome:
- 5
- Start:
- 132,996,985 bp from pter
- End:
- 133,026,617 bp from pter
- Size:
- 29,633 bases
- Orientation:
- Minus strand
Genomic View for ZCCHC10 Gene
Genes around ZCCHC10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.1 by Ensembl
- 5q31.1 by Entrez Gene
- 5q31.1 by HGNC
ZCCHC10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZCCHC10 Gene
Proteins for ZCCHC10 Gene
-
Protein details for ZCCHC10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TBK6-ZCH10_HUMAN
- Recommended name:
- Zinc finger CCHC domain-containing protein 10
- Protein Accession:
- Q8TBK6
- Q9NXR4
Protein attributes for ZCCHC10 Gene
- Size:
- 192 amino acids
- Molecular mass:
- 20967 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZCCHC10 Gene
Post-translational modifications for ZCCHC10 Gene
Other Protein References for ZCCHC10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZCCHC10
- Abcam antibodies for ZCCHC10 (Q8TBK6)
- GeneTex ZCCHC10 antibody for ZCCHC10
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZCCHC10
Protein Products
-
OriGene Purified Proteins for ZCCHC10
- Search Origene for MassSpec and Protein Over-expression Lysates for ZCCHC10
- Origene Custom Protein Services for ZCCHC10
- Search GeneTex for Proteins for ZCCHC10
Assay Products
No data available for DME Specific Peptides for ZCCHC10 Gene
Domains & Families for ZCCHC10 Gene
Gene Families for ZCCHC10 Gene
Protein Domains for ZCCHC10 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZCCHC10 Gene
Graphical View of Domain Structure for InterPro Entry
Q8TBK6- Similarity:
-
- Contains 1 CCHC-type zinc finger.
Function for ZCCHC10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for ZCCHC10 Gene
- GenomeRNAi human phenotypes for ZCCHC10:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
- Search ViGene Biosciences for ZCCHC10
CRISPR Products
-
OriGene CRISPR knockouts for ZCCHC10
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZCCHC10
- GenScript: Design CRISPR guide RNA sequences for ZCCHC10
miRNA Products
- Search ViGene Biosciences for ZCCHC10
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZCCHC10
- Browse OriGene Inhibitory RNA Products For ZCCHC10
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
Clone Products
- OriGene clones in human for ZCCHC10
- OriGene ORF clones in human,mouse,rat for ZCCHC10
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZCCHC10 Gene
Localization for ZCCHC10 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| mitochondrion | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC10 Gene
Pathways & Interactions for ZCCHC10 Gene
More details on SuperPathways for ZCCHC10
No Data Available
Interacting Proteins for ZCCHC10 Gene
Selected Interacting proteins:
Q8TBK6-ZCH10_HUMAN
ENSP00000324274
for ZCCHC10 Gene via
MINT
STRING
UniProtKB
I2D
No data available for Pathways by source and SIGNOR curated interactions for ZCCHC10 Gene
Transcripts for ZCCHC10 Gene
mRNA/cDNA for ZCCHC10 Gene
- (15) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (146) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZCCHC10 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZCCHC10
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZCCHC10
- GenScript: Design CRISPR guide RNA sequences for ZCCHC10
miRNA Products
- Search ViGene Biosciences for ZCCHC10
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZCCHC10
- Browse OriGene Inhibitory RNA Products For ZCCHC10
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
Clone Products
- OriGene clones in human for ZCCHC10
- OriGene ORF clones in human,mouse,rat for ZCCHC10
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | |||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||
| SP7: | - | - | - | - | - | ||||||||||||||||||||||
| SP8: | - | - | - | - | |||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | ||||||||||||||||||||
| SP10: |
Expression for ZCCHC10 Gene
This gene is overexpressed in Plasma (32.8) and CD8 Tcells (12.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZCCHC10 Gene
SOURCE GeneReport for Unigene cluster for ZCCHC10 Gene Hs.29700
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for ZCCHC10
-
OriGene qPCR primer pairs and template standards for ZCCHC10
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZCCHC10 Gene
Orthologs for ZCCHC10 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | ZCCHC10 36 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZCCHC10 36 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ZCCHC10 36 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Gm6214 36 |
|
OneToMany | |
| Zcchc10 36 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 36 |
|
OneToMany | |
| -- 36 |
|
OneToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | ZCCHC10 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZCCHC10 36 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ZCCHC10 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.6376 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zcchc10 36 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG5516 36 |
|
OneToOne |
- Species with no ortholog for ZCCHC10:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZCCHC10 Gene
(7) SIMAP similar genes for ZCCHC10 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for ZCCHC10 Gene
No data available for Paralogs for ZCCHC10 Gene
Variants for ZCCHC10 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs6596096 | -- | 133,013,126(+) | ggcaa(C/T)gcaca | intron-variant | |
| rs6859346 | -- | 132,999,473(+) | CCTCA(C/T)GTAGC | intron-variant | |
| rs3087646 | -- | 132,998,560(-) | TGGAC(C/T)GATGG | nc-transcript-variant, utr-variant-3-prime | |
| rs3210524 | -- | 132,997,818(-) | CTTAA(A/G)TAGAA | nc-transcript-variant, utr-variant-3-prime | |
| rs3885730 | -- | 133,026,202(-) | TATGC(C/T)CCTCC | intron-variant |
Residual Variation Intolerance Score:
34.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.57;
12.32% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ZCCHC10 Gene
- HapMap Linkage Disequilibrium report
- ZCCHC10
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZCCHC10 Gene
Disorders for ZCCHC10 Gene
Relevant External Links for ZCCHC10
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ZCCHC10
No disorders were found for ZCCHC10 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC10 Gene
Publications for ZCCHC10 Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
- Dynamic protein-protein interaction wiring of the human spliceosome. (PMID: 22365833) Hegele A. … Stelzl U. (Mol. Cell 2012) 3
Products for ZCCHC10 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ZCCHC10
- Search Origene for MassSpec and Protein Over-expression Lysates for ZCCHC10
- Origene Custom Protein Services for ZCCHC10
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for ZCCHC10
- Browse OriGene Inhibitory RNA Products For ZCCHC10
- OriGene qPCR primer pairs for ZCCHC10
- OriGene qPCR primer pairs and template standards for ZCCHC10
- OriGene CRISPR knockouts for ZCCHC10
- OriGene clones in human for ZCCHC10
- OriGene ORF clones in human,mouse,rat for ZCCHC10
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for ZCCHC10
- GenScript Custom Assay Services for ZCCHC10
- GenScript Custom overexpressing Cell Line Services for ZCCHC10
- GenScript: Design CRISPR guide RNA sequences for ZCCHC10
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ZCCHC10
- Novus Biologicals Antibodies for ZCCHC10
- Novus Biologicals proteins and lysates for ZCCHC10
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for ZCCHC10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
- Search ViGene Biosciences for ZCCHC10
- Search ViGene Biosciences for ZCCHC10
- Santa Cruz Biotechnology (SCBT) Antibodies for ZCCHC10
- Search Santa Cruz Biotechnology (SCBT) for ZCCHC10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ZCCHC10
Sources for ZCCHC10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon