Aliases for ZCCHC10 Gene
External Ids for ZCCHC10 Gene
- HGNC: 25954
- Entrez Gene: 54819
- Ensembl: ENSG00000155329
- UniProtKB: Q8TBK6
Previous GeneCards Identifiers for ZCCHC10 Gene
- GC05M132409
- GC05M132360
- GC05M132332
- GC05M127524
Summaries for ZCCHC10 Gene
GeneCards Summary for ZCCHC10 Gene
ZCCHC10 (Zinc Finger CCHC-Type Containing 10) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.
Additional gene information for ZCCHC10 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZCCHC10 Gene
Genomics for ZCCHC10 Gene
GeneHancer (GH) Regulatory Elements for ZCCHC10 Gene
Promoters and enhancers for ZCCHC10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ZCCHC10 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ZCCHC10 Gene
Genomic Locations for ZCCHC10 Gene
- chr5:132,996,985-133,026,617
- (GRCh38/hg38)
- Size:
- 29,633 bases
- Orientation:
- Minus strand
- chr5:132,332,677-132,362,296
- (GRCh37/hg19)
Genomic View for ZCCHC10 Gene
Genes around ZCCHC10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.1 by Ensembl
- 5q31.1 by Entrez Gene
- 5q31.1 by HGNC
ZCCHC10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZCCHC10 Gene
Proteins for ZCCHC10 Gene
-
Protein details for ZCCHC10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TBK6-ZCH10_HUMAN
- Recommended name:
- Zinc finger CCHC domain-containing protein 10
- Protein Accession:
- Q8TBK6
- Q9NXR4
Protein attributes for ZCCHC10 Gene
- Size:
- 192 amino acids
- Molecular mass:
- 20967 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZCCHC10 Gene
Post-translational modifications for ZCCHC10 Gene
No Post-translational modifications
Other Protein References for ZCCHC10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZCCHC10
-
Abcam antibodies for ZCCHC10
- Invitrogen Antibodies for ZCCHC10
- GeneTex ZCCHC10 antibody for ZCCHC10
Protein Products
-
OriGene Purified Proteins for ZCCHC10
- Search Origene for MassSpec and Protein Over-expression Lysates for ZCCHC10
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- Search GeneTex for Proteins for ZCCHC10
-
Abcam proteins for ZCCHC10
Assay Products
No data available for DME Specific Peptides for ZCCHC10 Gene
Domains & Families for ZCCHC10 Gene
Gene Families for ZCCHC10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ZCCHC10 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZCCHC10 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ZCCHC10 Gene
Function for ZCCHC10 Gene
Phenotypes From GWAS Catalog for ZCCHC10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZCCHC10 Gene
- GenomeRNAi human phenotypes for ZCCHC10:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
- Search ViGene Biosciences for ZCCHC10
CRISPR Products
-
OriGene CRISPR knockouts for ZCCHC10
- genomics-online: gRNA clones - Search results for 118 available ZCCHC10 gene related products
- Overview of 118 available ZCCHC10 gene related products
- Applied Biological Materials CRISPR for ZCCHC10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZCCHC10
- GenScript: Design CRISPR guide RNA sequences for ZCCHC10
miRNA Products
- Search ViGene Biosciences for ZCCHC10
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ZCCHC10
- Browse OriGene Inhibitory RNA Products For ZCCHC10
- genomics-online: shRNA clones - Search results for 118 available ZCCHC10 gene related products
- Overview of 118 available ZCCHC10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
Clone Products
- Sino Biological Human cDNA Clone for ZCCHC10
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for ZCCHC10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ZCCHC10
-
ViGene Biosciences adenoviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZCCHC10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZCCHC10 Gene
Localization for ZCCHC10 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| mitochondrion | 1 |
- Nucleoli (2)
- Nucleus (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZCCHC10 Gene
Pathways & Interactions for ZCCHC10 Gene
No Data Available
Interacting Proteins for ZCCHC10 Gene
Selected Interacting proteins:
Q8TBK6-ZCH10_HUMAN
ENSP00000324274
for ZCCHC10 Gene via
MINT
UniProtKB
IID
STRING
No data available for Pathways by source and SIGNOR curated interactions for ZCCHC10 Gene
Transcripts for ZCCHC10 Gene
mRNA/cDNA for ZCCHC10 Gene
- (12) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (146) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZCCHC10 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZCCHC10
- genomics-online: gRNA clones - Search results for 118 available ZCCHC10 gene related products
- Overview of 118 available ZCCHC10 gene related products
- Applied Biological Materials CRISPR for ZCCHC10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZCCHC10
- GenScript: Design CRISPR guide RNA sequences for ZCCHC10
miRNA Products
- Search ViGene Biosciences for ZCCHC10
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ZCCHC10
- Browse OriGene Inhibitory RNA Products For ZCCHC10
- genomics-online: shRNA clones - Search results for 118 available ZCCHC10 gene related products
- Overview of 118 available ZCCHC10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZCCHC10 gene
Clone Products
- Sino Biological Human cDNA Clone for ZCCHC10
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for ZCCHC10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | |||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||
| SP7: | - | - | - | - | - | ||||||||||||||||||||||
| SP8: | - | - | - | - | |||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | ||||||||||||||||||||
| SP10: |
Expression for ZCCHC10 Gene
This gene is overexpressed in Plasma (32.8) and CD8 Tcells (12.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZCCHC10 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ZCCHC10 Gene:
ZCCHC10SOURCE GeneReport for Unigene cluster for ZCCHC10 Gene:
Hs.29700Evidence on tissue expression from TISSUES for ZCCHC10 Gene
- Nervous system(4.3)
- Intestine(4.2)
Primer Products
-
OriGene qPCR primer pairs for ZCCHC10
-
OriGene qPCR primer pairs and template standards for ZCCHC10
- genomics-online: primer clones - Search results for 118 available ZCCHC10 gene related products
- Overview of 118 available ZCCHC10 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZCCHC10 Gene
Orthologs for ZCCHC10 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | ZCCHC10 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZCCHC10 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | ZCCHC10 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Zcchc10 34 |
|
OneToMany | |
| Gm6214 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | ZCCHC10 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZCCHC10 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ZCCHC10 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.6376 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | zcchc10 34 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG5516 34 |
|
OneToOne |
- Species where no ortholog for ZCCHC10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZCCHC10 Gene
(7) SIMAP similar genes for ZCCHC10 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for ZCCHC10 Gene
No data available for Paralogs for ZCCHC10 Gene
Variants for ZCCHC10 Gene
| SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000072463 | -- | 133,010,699(-) | G/A | intron_variant | |
| rs1000123952 | -- | 132,998,181(-) | AACA/ | 3_prime_UTR_variant, non_coding_transcript_variant | |
| rs1000278132 | -- | 133,007,409(-) | G/A | intron_variant | |
| rs1000372793 | -- | 133,004,652(-) | C/A | intron_variant | |
| rs1000441185 | -- | 133,000,855(-) | C/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1022039 | CNV | gain | 25217958 |
| nsv1073495 | CNV | deletion | 25765185 |
| nsv1117581 | CNV | deletion | 24896259 |
| nsv1131915 | CNV | deletion | 24896259 |
| nsv1131916 | CNV | deletion | 24896259 |
| nsv1135956 | CNV | deletion | 24896259 |
| nsv830489 | CNV | loss | 17160897 |
| nsv830490 | CNV | gain | 17160897 |
| nsv968988 | CNV | duplication | 23825009 |
| nsv980725 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
34.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.57;
12.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZCCHC10 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZCCHC10
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZCCHC10 Gene
Disorders for ZCCHC10 Gene
Additional Disease Information for ZCCHC10
No disorders were found for ZCCHC10 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZCCHC10 Gene
Publications for ZCCHC10 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
Products for ZCCHC10 Gene
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- genomics-online: cdna clones - Search results for 118 available ZCCHC10 gene related products
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- Overview of 118 available ZCCHC10 gene related products
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- Overview of 118 available ZCCHC10 gene related products
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- Overview of 118 available ZCCHC10 gene related products
Sources for ZCCHC10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew