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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZC3HC1 Gene

protein-coding GIFtS: 52
GCID: GC07M129658

zinc finger, C3HC-type containing 1

Explore 5 diseases affiliated with
ZC3HC1 via

MalaCards

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zinc Finger, C3HC-Type Containing 1¹ ²		Hematopoietic Stem/Progenitor Cell Protein 216²
NIPA¹ ² ³		Nuclear Interacting Partner Of Anaplastic Lymphoma Kinase (ALK)²
Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase² ³		Nuclear Interaction Partner Of ALK²
Zinc Finger C3HC-Type Protein 1² ³		Nuclear-Interacting Partner Of ALK²
HNIPA¹		Zinc Finger, C3HC Type 1²
1110054L24Rik²

External Ids:	HGNC: 29913¹	Entrez Gene: 51530²	Ensembl: ENSG00000091732⁷	UniProtKB: Q86WB0³

Export aliases for ZC3HC1 gene to outside databases

Previous GC identifers: GC07M129253 GC07M129445 GC07M124019

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Function: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by

mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation

regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its

inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an

antiapoptotic role in NPM-ALK-mediated signaling events

Gene Wiki entry for ZC3HC1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZC3HC1 gene promoter:
Max1 GATA-1 AREB6 Max CBF-A CBF-B STAT3 c-Myc CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZC3HC1 promoter sequence

Search SABiosciences Chromatin IP Primers for ZC3HC1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZC3HC1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32.2 Ensembl cytogenetic band: 7q32.2 HGNC cytogenetic band: 7q32.2

ZC3HC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZC3HC1 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M129658: view genomic region (about GC identifiers)

Start:	129,658,126 bp from pter	End:	129,691,291 bp from pter
Size:	33,166 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 129,042,758-129,076,662

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0 (See protein sequence)

Recommended Name: Nuclear-interacting partner of ALK

Size: 502 amino acids; 55262 Da

Subunit: Interacts with the NPM-ALK fusion protein in a tyrosine phosphorylation-dependent manner. Interacts with SKP1.

Component of a SCF(NIPA) E3 complex with SKP1, RBX1 and CUL1 when not phosphorylated on Ser-354. Interacts with CCNB1

Subcellular location: Nucleus

Developmental stage: Weakly expressed in G0/G1 phases, abundant during S and G2/M phases, and strongly decreases

thereafter

Caution: Reported to contain a F-box domain (PubMed:16009132). Such domain is however not predicted by any detection

method

Sequence caution: Sequence=AAF36136.1; Type=Frameshift; Positions=93, 187, 220; Sequence=AAH28917.1; Type=Erroneous

initiation; Sequence=AAS07546.1; Type=Erroneous gene model prediction; Sequence=AAS07547.1; Type=Erroneous gene model

prediction;

Secondary accessions: A6NH66 Q75MF3 Q75MF4 Q8N330 Q96F75 Q9HA34 Q9NVX4 Q9P0R0

Alternative splicing: 3 isoforms: Q86WB0-1 Q86WB0-2 Q86WB0-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZC3HC1: NX_Q86WB0

Post-translational modifications:

Phosphorylated. Phosphorylated on Ser residues at G2/M phase, but not during S and G0 phases. May also be weakly

phosphorylated on Tyr residues. Ser-354 phosphorylation, a major site during the course of cell-cycle-dedendent

phosphorylation, results in its dissociation from the SCF(NIPA) complex, thereby preventing CCNB1 degradation leading

to mitotic entry¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q86WB0

ZC3HC1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057562.3

ENSEMBL proteins:

ENSP00000351052 ENSP00000353933 ENSP00000419509 ENSP00000418533 ENSP00000417682

ENSP00000418407 ENSP00000420068 ENSP00000417217 ENSP00000309301

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	Uscn Proteins for ZC3HC1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0031965	nuclear membrane	IDA	--

ZC3HC1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZC3HC1 for domains About GeneDecksing

2 InterPro domains/families:

IPR013909 NIPA/Rsm1

IPR012935 Znf_C3HC-like

Graphical View of Domain Structure for InterPro Entry Q86WB0

ProtoNet protein and cluster: Q86WB0

1 Blocks protein family: IPB012935 Zinc finger

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Domain: The F-box-like region is required for the interaction with SKP1

Similarity: Contains 1 C3HC-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Function: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by

mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation

regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its

inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an

antiapoptotic role in NPM-ALK-mediated signaling events

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		hsa-miR-589*
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3HC1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	16105984
GO:0008270	zinc ion binding	IEA	--
GO:0019901	protein kinase binding	IPI	16105984

ZC3HC1 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for ZC3HC1:

Decreased viability of wild-ty

Animal Models:
Mouse knock-out Zc3hc1^tm1.2Jduy for ZC3HC1
12 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Zc3hc1):

behavior/neurological	cellular	craniofacial	endocrine/exocrine gland	growth/size
hematopoietic system	homeostasis/metabolism	immune system	mortality/aging	no phenotypic analysis
reproductive system	skeleton

ZC3HC1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cell Cycle / Checkpoint Control

Cell Cycle / Checkpoint Control

1.00

Apoptosis and Autophagy

Apoptosis and Autophagy

1.00

Protein Stability

Protein Stability

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Cell Signaling Technology (CST) Pathways for ZC3HC1

	Apoptosis and Autophagy
	Cell Cycle / Checkpoint Control
	Protein Stability

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Pathway: Protein modification; protein ubiquitination

ZC3HC1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZC3HC1

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

5/535 Interacting proteins for ZC3HC1 (Q86WB0^{2, 3} ENSP00000351052⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 535)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CCNB1	P14635²^,³, ENSP00000256442⁴	MINT-7947479 I2D: score=2 STRING: ENSP00000256442
PDPK1	O15530²^,³	MINT-8265665 I2D: score=2
TNFSF11	O14788²^,³	MINT-8274797 I2D: score=2
TSC22D1	Q15714²^,³	MINT-8275644 I2D: score=2
CUL1	Q13616²^,³, ENSP00000326804⁴	MINT-7947479 I2D: score=2 STRING: ENSP00000326804

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007067	mitosis	IEA	--
GO:0016567	protein ubiquitination	IEA	--
GO:0043066	negative regulation of apoptotic process	IEA	--
GO:0051301	cell division	IEA	--

ZC3HC1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZC3HC1
Search CenterWatch for drugs/clinical trials and news about ZC3HC1 / NIPA

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZC3HC1 gene:

NM_016478.3

Unigene Cluster for ZC3HC1:

Zinc finger, C3HC-type containing 1

Hs.194157 [show with all ESTs]

Unigene Representative Sequence: NM_016478

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000358303(uc010lma.3 uc003vpi.3) ENST00000360708 ENST00000467642

ENST00000481503 ENST00000477578 ENST00000471022 ENST00000483827 ENST00000480193

ENST00000470651 ENST00000484432 ENST00000311873

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		hsa-miR-589*
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Additional cDNA sequence:

AF151050.1 AJ537494.1 AK001317.1 AK022373.1 BC000190.1 BC011551.1 BC028917.1

12 DOTS entries:

DT.316743 DT.100774889 DT.40108337 DT.75177243 DT.91787394 DT.100738541 DT.100804029 DT.121039330

DT.95193685 DT.100786778 DT.121039322 DT.92435144

24/211 AceView cDNA sequences (see all 211):

BM719894 CR607048 BX384219 CR617545 CR618908 BM843455 BM823327 BM466507

BC000190 CB137494 BM795918 BQ645081 BQ651241 BU844456 BM013594 BQ653235

BM843186 CR603577 BQ962845 AJ537494 BX333474 BM795545 BU540711 BU194234

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3HC1 (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	·	8c	^	9	^	10	^	11a	·	11b	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15
SP1:													-		-		-		-		-				-						-
SP2:									-				-		-		-		-		-				-						-
SP3:									-						-		-		-		-		-		-						-
SP4:																															-
SP5:									-		-		-				-				-				-

ECgene alternative splicing isoforms for ZC3HC1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZC3HC1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTCTGTTAA

About this image
See ZC3HC1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZC3HC1

SOURCE GeneReport for Unigene cluster: Hs.194157

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Tissue specificity: Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain,

placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not

expressed in leukocytes

SABiosciences Expression via Pathway-Focused PCR Array including ZC3HC1:

Apoptosis 384HT in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZC3HC1 gene from 7/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zc3hc1^{1 , 5}	zinc finger, C3HC type 1^{1, 5}	84.06(n)¹ 85.18(a)¹		6 (12.52 cM)⁵ 232679¹ NM_172735.2¹ NP_766323.1¹ 30366380⁵
chicken (Gallus gallus)	Aves	ZC3HC1¹	zinc finger, C3HC-type containing 1	65.76(n) 65.34(a)		416679 NM_001199437.1 NP_001186366.1
lizard (Anolis carolinensis)	Reptilia	ZC3HC1⁶	--	58(a)	1 ↔ 1	GL343708.1(158993-194906)
African clawed frog (Xenopus laevis)	Amphibia	MGC68711²	hypothetical protein MGC68711	75.12(n)		BC061669.1
zebrafish (Danio rerio)	Actinopterygii	zc3hc1¹	zinc finger, C3HC-type containing 1	57.11(n) 49.45(a)		560141 NM_001077378.1 NP_001070846.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G48950⁶ ATILP1⁶	IAP-like protein 1	15(a) 11(a)	many → 1 many → 1	1(18106897-18110237) 1(5880130-5884756)
rice (Oryza sativa)	Liliopsida	-- -- (see all 3)	zinc ion binding protein, putative, expressed (see all 3)	12(a) 11(a) (see all 3)	many → 1 many → 1 (see all 3)	7(2633332-2639491) 1(23854684-23860796)

ENSEMBL Gene Tree for ZC3HC1 (if available)
TreeFam Gene Tree for ZC3HC1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140757788^1,2		--	129657635(+)	`TACTTC/TAGTAC`	1	--	int¹		0	--	--	--	--
rs144626988^1,2		--	129657687(+)	`CATATC/TAGAGA`	1	--	int¹		0	--	--	--	--
rs73479682^1,2	C,	--	129657851(+)	`GAGGGG/TTCTCT`	1	--	int¹		1		WA	2
rs2242487^1,2	C,F,A,H,	--	129657882(+)	`ATTACG/ATTGTT`	1	--	int¹		26		EA NS NA WA	3194
rs112843375^1,2		--	129658049(+)	`GCCAAC/TCTGAA`	1	--	int¹		1		CSA	2
rs141220042^1,2		--	129658066(+)	`AAGTTA/GAATGT`	1	--	int¹		0	--	--	--	--
rs55902062^1,2	C,F,	--	129658088(+)	`TTCTCC/GGGCCC`	1	--	int¹		1		NA	120
rs1997081^1,2	C,H,	--	129658259(+)	`GTTAAC/TCCCAC`	1	--	ut3¹ ese³		16		NA WA CSA EA	513
rs114626883^1,2	C,F,	--	129658269(+)	`CACTCC/ATTTAA`	1	--	ut3¹		1		WA	118
rs138876979^1,2		--	129658271(+)	`CTCCTC/TTAACA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZC3HC1 (129658126 - 129691291 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZC3HC1: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ZC3HC1 for disorders About GeneDecksing

5 diseases for ZC3HC1: About MalaCards

hepatitis e ehrlichiosis gigantism hepatitis

prostatitis

Human Genome Epidemiology (HuGE) Navigator: ZC3HC1 (2 documents)

Export disorders for ZC3HC1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ZC3HC1 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with ZC3HC1)

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Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2, 3} Zhang Q.-H.... Chen Z. (2000)
Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA). (PubMed id 12748172)^{1, 2, 9} Ouyang T.... Duyster J. (2003)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{1, 2} Beausoleil S.A.... Gygi S.P. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry. (PubMed id 16009132)^{1, 2} Bassermann F.... Duyster J. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51530	HGNC: 29913	AceView: NIPA	Ensembl:ENSG00000091732	euGenes: HUgn51530
ECgene: ZC3HC1	H-InvDB: ZC3HC1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZC3HC1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ZC3HC1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ZC3HC1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ZC3HC1 gene:
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ZC3HC1 Gene

zinc finger, C3HC-type containing 1

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ZC3HC1 Gene

zinc finger, C3HC-type containing 1

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