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ZC3HC1 Gene

protein-coding GIFtS: 53

GC07M129445

zinc finger, C3HC-type containing 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
1110054L24Rik ^²
HSPC216 ^²
NIPA ^¹, ², ³
hNIPA ^³

Descriptions
Nuclear-interacting partner of anaplastic lymphoma kinase ^³
Zinc finger C3HC-type protein 1 ^³
hematopoietic stem/progenitor cell protein 216 ^²
nuclear interacting partner of anaplastic lymphoma kinase (ALK) ^²
nuclear interaction partner of ALK ^²
zinc finger, C3HC type 1 ^²
zinc finger, C3HC-type containing 1 ^²

External Ids
HGNC: 29913¹
Entrez Gene: 51530²
UniProtKB: Q86WB0³
Ensembl: ENSG00000091732⁷

Search outside databases for aliases for ZC3HC1 gene

Previous GC identifer: GC07M129253

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Function: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls

mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its

cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting

CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of

CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in

NPM-ALK-mediated signaling events

Gene Wiki entry for ZC3HC1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ZC3HC1 gene

Entrez Gene cytogenetic band: 7q32.2 Ensembl cytogenetic band: 7q32.2 HGNC cytogenetic band: 7q32.2

ZC3HC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M129445: (about GC identifiers)

Start:	129,445,362 bp from pter
End:	129,478,469 bp from pter
Size:	33,108 bases
Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 129,042,758-129,076,662

RefSeq DNA sequence:

NC_000007.12 NT_007933.14 NT_079596.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0 (See protein sequence)

Recommended Name: Nuclear-interacting partner of ALK

Size: 502 amino acids; 55262 Da

Subunit: Interacts with the NPM-ALK fusion protein in a tyrosine phosphorylation-dependent manner.

Interacts with SKP1. Component of a SCF(NIPA) E3 complex with SKP1A, RBX1 and CUL1 when not

phosphorylated on Ser-354. Interacts with CCNB1

Subcellular location: Nucleus

Developmental stage: Weakly expressed in G0/G1 phases, abundant during S and G2/M phases, and

strongly decreases thereafter

Caution: Reported to contain a F-box domain (PubMed:16009132). Such domain is however not predicted

by any detection method

Sequence caution: Sequence=AAF36136.1; Type=Frameshift; Positions=93, 187, 220;

Sequence=AAS07546.1; Type=Erroneous gene model prediction; Sequence=AAS07547.1; Type=Erroneous

gene model prediction;

Secondary accessions: A6NH66 Q75MF3 Q75MF4 Q8N330 Q96F75 Q9HA34 Q9NVX4 Q9P0R0

Alternative splicing: 3 isoforms: Q86WB0-1 Q86WB0-2 Q86WB0-3

Post-translational modifications:

Phosphorylated. Phosphorylated on Ser residues at G2/M phase, but not during S and G0 phases. May

also be weakly phosphorylated on Tyr residues. Ser-354 phosphorylation, a major site during the

course of cell-cycle-dedendent phosphorylation, results in its dissociation from the SCF(NIPA)

complex, thereby preventing CCNB1 degradation leading to mitotic entry¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_057562.3

ENSEMBL proteins:

ENSP00000353933 ENSP00000351052 ENSP00000309301

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NIPA)
	Human Recombinant Proteins from Abnova (ZC3HC1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

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Antibodies for ZC3HC1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ZC3HC1
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for ZC3HC1 (NIPA)
	Antibodies from Abcam (NIPA), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ZC3HC1)
	Novus Biologicals Antibody for ZC3HC1

Assays for ZC3HC1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q86WB0

ProtoNet protein and cluster: Q86WB0

1 Blocks protein family: IPB012935 Zinc finger

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Domain: The F-box-like region is required for the interaction with SKP1A

Similarity: Contains 1 C3HC-type zinc finger

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ZC3HC1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016478

Applied Biosystems Silencer® siRNAs for ZC3HC1

Sigma-Aldrich siRNA for ZC3HC1

Sigma-Aldrich shRNA Panels and shRNA for ZC3HC1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ZC3HC1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_016478
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016478
untagged cDNA clone in CMV expression vector: NM_016478

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_016478

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Function: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls

mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its

cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting

CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of

CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in

NPM-ALK-mediated signaling events

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008270	zinc ion binding	IEA	--
GO:0019901	protein kinase binding	IPI	16105984
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0

Pathway: Protein modification; protein ubiquitination

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007049	cell cycle	IEA	--
GO:0007067	mitosis	IEA	--
GO:0019941	modification-dependent protein catabolic process	IEA	--
GO:0051301	cell division	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ZC3HC1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ZC3HC1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016478

Sigma-Aldrich siRNA for ZC3HC1

Sigma-Aldrich shRNA Panels and shRNA for ZC3HC1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_016478

REFSEQ mRNAs for ZC3HC1 gene:

NM_016478.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_016478

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_016478
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_016478
                                 untagged cDNA clone in CMV expression vector: NM_016478

Additional cDNA sequence:

AF151050.1 AJ537494.1 AK001317.1 AK022373.1 BC000190.1 BC011551.1 BC028917.1 CR603577.1

CR607048.1 CR617545.1 CR618908.1

11 DOTS entries:

DT.316743 DT.100774889 DT.100804029 DT.40108337 DT.75177243 DT.91787394 DT.121039330 DT.95193685

DT.100738541 DT.92435144 DT.121039322

24/211 AceView cDNA sequences (see all 211 ):

BM843455 BU844456 CR603577 BQ651241 AJ537494 BQ653235 BC000190 CR607048

BX384219 BM719894 BI224212 BM795545 CR617545 BX333474 CR618908 BM823327

BM013594 BM795918 BQ645081 BU194234 CB137494 BU540711 BQ962845 BM843186

highest scoring ESTs for ZC3HC1:

AA039602 AA070015 AF151050 AI828094 AJ537494 AK001317 AK022373 AU122259 AW247353 BC000190

Unigene Cluster for ZC3HC1:

Zinc finger, C3HC-type containing 1

Hs.194157 [show with all ESTs]

Unigene Representative Sequence: NM_016478

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3HC1 (see all 9 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	·	8c	^	9	^	10	^	11a	·	11b	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15
SP1:													-		-		-		-		-				-						-
SP2:									-				-		-		-		-		-				-						-
SP3:									-						-		-		-		-		-		-						-
SP4:																															-
SP5:									-		-		-				-				-				-

About this scheme

ECgene alternative splicing isoforms for ZC3HC1

3 Ensembl transcripts including schematic representations:

ENST00000360708 ENST00000358303 ENST00000311873

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ZC3HC1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ZC3HC1

¹ / ² / ³

3 probe-sets matching ZC3HC1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
78439_at²^{, 3}	U95-E	1	1.00	1.00	1.00	1.00	AI828094	0.80	1.00	0.91	1
223163_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC000190	0.80	1.00	0.91	1
223163_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTTCTGTTAA

SOURCE GeneReport for Unigene cluster: Hs.194157
UniProtKB/Swiss-Prot: NIPA_HUMAN, Q86WB0
Tissue specificity: Widely expressed. Highly expressed in heart, skeletal muscle and testis.
Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small
intestine and colon. Weakly or not expressed in leukocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ZC3HC1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	LOC475196¹	--	similar to zinc finger, C3HC type 1	91.02(n) 93.41(a)	475196 XM_532428.2 XP_532428.2
chimpanzee (Pan troglodytes)	ZC3HC1¹	--	zinc finger, C3HC-type containing 1	99.34(n) 99(a)	463722 XM_001156206.1 XP_001156206.1
cow (Bos taurus)	ZC3HC1¹	--	zinc finger, C3HC-type containing 1	89.75(n) 91.22(a)	533550 NM_001034591.1 NP_001029763.1
rat (Rattus norvegicus)	Zc3hc1¹	--	zinc finger, C3HC-type containing 1	84.33(n) 86.2(a)	296957 XM_216113.4 XP_216113.4
mouse (Mus musculus)	Zc3hc1^{1, 5}	6⁵	zinc finger, C3HC type 1^{1, 5}	84.06(n)¹ 85.18(a)¹	232679¹ NM_172735.2¹ NP_766323.1¹ AI848853⁵ AJ537495⁵ (see all 21)

About this table Species with no ortholog for ZC3HC1

ENSEMBL Gene Tree for ZC3HC1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/182 NCBI SNPs in ZC3HC1 are shown (see all 182 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 48)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1464890^1,2	A,C,F,H,O	129451548(+)	`ACATGC/TTATCA`	1	T/A	mis¹		19	EA NA MN EU WA	2974
	rs867704^1,2	A,C,F,H,O	129478545(+)	`AAAGTC/GTAACC`	1	--	ng3¹		19	NA EA EU WA MN	2440
	rs11556924^1,2	A,C,F,H	129450732(+)	`CAGGAC/TGGTCA`	1	R/H	mis¹		12	EU EA WA	1254
	rs2242487^1,2	A,C,F,H	129445118(+)	`ATTACG/ATTGTT`	1	--	ng5¹		12	EA EU WA NA	1676
	rs11972756^1,2	C,F,H	129479903(+)	`tatcaA/Gtgttc`	1	--	ng3¹		4	EU EA WA	418
--	rs11556923^1,2	H	129451493(+)	`TGGACG/AATTCA`	1	L/S	mis¹ ese³		4	EU EA WA	402
	rs1997081^1,2	C	129445495(+)	`GTTAAC/TCCCAC`	1	--	ut3¹ ese³		3	NA	136
--	rs10231342^1,2	H	129479402(+)	`cccagC/Aaattt`	1	--	ng3¹		4	EU EA WA	420
	rs2140873^1,2	A,C,F,H,O	129476986(+)	`CCTTTG/CATACC`	1	--	int¹		6	EU EA NA	430
	rs2242488^1,2	A,C,F,H,O	129445891(+)	`TCTGGG/ATATGT`	1	--	int¹		8	EA NA EU WA	1618

About this table

HapMap Linkage Disequilibrium images for ZC3HC1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/19 PubMed articles for ZC3HC1 gene (see all 19 ):

Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{2, 3, 4} Zhang Q.H....Chen Z. (2000)
Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA). (PubMed id 12748172)^{1, 3, 4} Ouyang T.... Duyster J. (2003)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry. (PubMed id 16009132)^{3, 4} Bassermann F.... Duyster J. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)⁴ Cantin G.T....Yates J.R. III (2008)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)⁴ Daub H.... Mann M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 51530	HGNC: 29913	AceView: NIPA	Ensembl:ENSG00000091732	euGenes: HUgn51530
ECgene: ZC3HC1	H-InvDB: ZC3HC1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ZC3HC1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ZC3HC1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ZC3HC1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ZC3HC1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ZC3HC1		Antibodies for ZC3HC1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ZC3HC1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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Antibodies & Assays for ZC3HC1 (NIPA)

	Recombinant Proteins (NIPA)
	Antibodies (NIPA)

Search OriGene for ZC3HC1

Search Tocris compounds for ZC3HC1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ZC3HC1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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ZC3HC1 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for ZC3HC1

Summaries
for ZC3HC1

Genomic Location
for ZC3HC1

Proteins
for ZC3HC1

Protein Domains/
Families
for ZC3HC1

Gene Function
for ZC3HC1

Pathways & Interactions
for ZC3HC1

Drugs & Compounds
for ZC3HC1

Transcripts
for ZC3HC1

Expression
for ZC3HC1

Orthologs
for ZC3HC1

Paralogs
for ZC3HC1

SNPs/Variants
for ZC3HC1

Disorders & Mutations
for ZC3HC1

Medical News
for ZC3HC1

Publications
for ZC3HC1

Search for ZC3HC1

Genome Databases showing ZC3HC1

Other Databases showing ZC3HC1

Specialized Databases showing ZC3HC1

Licensable Technologies
for ZC3HC1

Services
for ZC3HC1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ZC3HC1 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor ZC3HC1

Summariesfor ZC3HC1

Genomic Locationfor ZC3HC1

Proteinsfor ZC3HC1

Protein Domains/Familiesfor ZC3HC1

Gene Functionfor ZC3HC1

Pathways & Interactionsfor ZC3HC1

Drugs & Compoundsfor ZC3HC1

Transcriptsfor ZC3HC1

Expression for ZC3HC1

Orthologsfor ZC3HC1

Paralogsfor ZC3HC1

SNPs/Variantsfor ZC3HC1

Disorders & Mutationsfor ZC3HC1

Medical Newsfor ZC3HC1

Publicationsfor ZC3HC1

Search for ZC3HC1

Genome Databases showing ZC3HC1

Other Databases showing ZC3HC1

Specialized Databases showing ZC3HC1

Licensable Technologiesfor ZC3HC1

Servicesfor ZC3HC1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ZC3HC1

Summaries
for ZC3HC1

Genomic Location
for ZC3HC1

Proteins
for ZC3HC1

Protein Domains/
Families
for ZC3HC1

Gene Function
for ZC3HC1

Pathways & Interactions
for ZC3HC1

Drugs & Compounds
for ZC3HC1

Transcripts
for ZC3HC1

Expression
for ZC3HC1

Orthologs
for ZC3HC1

Paralogs
for ZC3HC1

SNPs/Variants
for ZC3HC1

Disorders & Mutations
for ZC3HC1

Medical News
for ZC3HC1

Publications
for ZC3HC1

Licensable Technologies
for ZC3HC1

Services
for ZC3HC1