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Aliases for ZC3HAV1L Gene

Aliases for ZC3HAV1L Gene

  • Zinc Finger CCCH-Type, Antiviral 1-Like 2 3
  • C7orf39 3 4
  • Chromosome 7 Open Reading Frame 39 2

External Ids for ZC3HAV1L Gene

Previous HGNC Symbols for ZC3HAV1L Gene

  • C7orf39

Previous GeneCards Identifiers for ZC3HAV1L Gene

  • GC07M138357
  • GC07M138706
  • GC07M133020

Summaries for ZC3HAV1L Gene

GeneCards Summary for ZC3HAV1L Gene

ZC3HAV1L (Zinc Finger CCCH-Type, Antiviral 1-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC3HAV1L Gene

Genomics for ZC3HAV1L Gene

Regulatory Elements for ZC3HAV1L Gene

Genomic Location for ZC3HAV1L Gene

139,021,498 bp from pter
139,036,489 bp from pter
14,992 bases
Minus strand

Genomic View for ZC3HAV1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC3HAV1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC3HAV1L Gene

Proteins for ZC3HAV1L Gene

  • Protein details for ZC3HAV1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger CCCH-type antiviral protein 1-like
    Protein Accession:
    Secondary Accessions:
    • Q8WUD9

    Protein attributes for ZC3HAV1L Gene

    300 amino acids
    Molecular mass:
    32962 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZC3HAV1L Gene


neXtProt entry for ZC3HAV1L Gene

Proteomics data for ZC3HAV1L Gene at MOPED

Post-translational modifications for ZC3HAV1L Gene

  • Ubiquitination at Lys 141 and Lys 174
  • Modification sites at PhosphoSitePlus

Other Protein References for ZC3HAV1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZC3HAV1L Gene

Domains & Families for ZC3HAV1L Gene

Protein Domains for ZC3HAV1L Gene


Suggested Antigen Peptide Sequences for ZC3HAV1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZC3HAV1L: view

No data available for Gene Families and UniProtKB/Swiss-Prot for ZC3HAV1L Gene

Function for ZC3HAV1L Gene

Phenotypes for ZC3HAV1L Gene

genes like me logo Genes that share phenotypes with ZC3HAV1L: view

Animal Model Products

CRISPR Products

miRNA for ZC3HAV1L Gene

miRTarBase miRNAs that target ZC3HAV1L

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC3HAV1L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for ZC3HAV1L Gene

Localization for ZC3HAV1L Gene

Subcellular locations from

Jensen Localization Image for ZC3HAV1L Gene COMPARTMENTS Subcellular localization image for ZC3HAV1L gene
Compartment Confidence
cytosol 3
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZC3HAV1L Gene

Pathways & Interactions for ZC3HAV1L Gene

SuperPathways for ZC3HAV1L Gene

No Data Available

Interacting Proteins for ZC3HAV1L Gene

Gene Ontology (GO) - Biological Process for ZC3HAV1L Gene


No data available for Pathways by source and SIGNOR curated interactions for ZC3HAV1L Gene

Drugs & Compounds for ZC3HAV1L Gene

No Compound Related Data Available

Transcripts for ZC3HAV1L Gene

mRNA/cDNA for ZC3HAV1L Gene

Unigene Clusters for ZC3HAV1L Gene

Zinc finger CCCH-type, antiviral 1-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC3HAV1L

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZC3HAV1L Gene

No ASD Table

Relevant External Links for ZC3HAV1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZC3HAV1L Gene

mRNA expression in normal human tissues for ZC3HAV1L Gene

Protein differential expression in normal tissues from HIPED for ZC3HAV1L Gene

This gene is overexpressed in Uterus (12.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZC3HAV1L Gene

SOURCE GeneReport for Unigene cluster for ZC3HAV1L Gene Hs.512833

genes like me logo Genes that share expression patterns with ZC3HAV1L: view

Protein tissue co-expression partners for ZC3HAV1L Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZC3HAV1L Gene

Orthologs for ZC3HAV1L Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZC3HAV1L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZC3HAV1L 35
  • 85.55 (n)
  • 83.28 (a)
  • 81 (a)
(Canis familiaris)
Mammalia ZC3HAV1L 35
  • 86.62 (n)
  • 87.9 (a)
  • 89 (a)
(Mus musculus)
Mammalia Zc3hav1l 35
  • 82.64 (n)
  • 76.55 (a)
Zc3hav1l 16
Zc3hav1l 36
  • 75 (a)
(Pan troglodytes)
Mammalia ZC3HAV1L 35
  • 99.44 (n)
  • 99.33 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Zc3hav1l 35
  • 82.19 (n)
  • 78.42 (a)
(Monodelphis domestica)
Mammalia ZC3HAV1L 36
  • 48 (a)
Species with no ortholog for ZC3HAV1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZC3HAV1L Gene

Gene Tree for ZC3HAV1L (if available)
Gene Tree for ZC3HAV1L (if available)

Paralogs for ZC3HAV1L Gene

(2) SIMAP similar genes for ZC3HAV1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZC3HAV1L: view

No data available for Paralogs for ZC3HAV1L Gene

Variants for ZC3HAV1L Gene

Sequence variations from dbSNP and Humsavar for ZC3HAV1L Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs546700 -- 139,031,485(+) ggagg(A/C)tgagg intron-variant
rs635770 -- 139,030,558(-) agcca(C/T)cacac intron-variant
rs1047459 -- 139,022,071(-) TTTTT(C/T)ATTAT utr-variant-3-prime
rs1394491 -- 139,037,358(-) GCACT(C/G)AGGAG upstream-variant-2KB
rs2279860 -- 139,036,275(-) CAGGC(C/T)TCGCC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZC3HAV1L Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073
nsv831155 CNV Loss 17160897

Variation tolerance for ZC3HAV1L Gene

Residual Variation Intolerance Score: 70.88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.85; 58.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZC3HAV1L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZC3HAV1L Gene

Disorders for ZC3HAV1L Gene

Relevant External Links for ZC3HAV1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZC3HAV1L: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZC3HAV1L Gene

Publications for ZC3HAV1L Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 67
  3. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 67
  4. Detection of a common chimeric transcript between human chromosomes 7 and 16. (PMID: 23273016) Fang W. … Landweber L.F. (Biol. Direct 2012) 67
  5. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67

Products for ZC3HAV1L Gene

Sources for ZC3HAV1L Gene

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