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ZC3H7B Gene

protein-coding   GIFtS: 52
GCID: GC22P041697

Zinc Finger CCCH-Type Containing 7B

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger CCCH-Type Containing 7B1 2     Rotavirus X Protein Associated With NSP32
Rotavirus 'X'-Associated Non-Structural Protein2 3     Ubiquitous Tetratricopeptide Containing Protein RoXaN2
RoXaN2 3     Zinc Finger CCCH Domain-Containing Protein 7B2
Rotavirus 'X' Associated Non-Structural Protein2     KIAA10313

External Ids:    HGNC: 308691   Entrez Gene: 232642   Ensembl: ENSG000001004037   UniProtKB: Q9UGR23   

Export aliases for ZC3H7B gene to outside databases

Previous GC identifers: GC22P040023 GC22P024664


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZC3H7B Gene:
This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts
with the rotavirus non-structural protein NSP3. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZC3H7B Gene:
ZC3H7B (zinc finger CCCH-type containing 7B) is a protein-coding gene. An important paralog of this gene is ZC3H7A.

Gene Wiki entry for ZC3H7B (Roxan) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZC3H7B gene promoter:
         AhR   CREB   AP-1   deltaCREB   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZC3H7B promoter sequence
   Search Chromatin IP Primers for ZC3H7B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZC3H7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

ZC3H7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZC3H7B gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P041697:  view genomic region     (about GC identifiers)

Start:
41,697,526 bp from pter      End:
41,756,151 bp from pter
Size:
58,626 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: Z3H7B_HUMAN, Q9UGR2 (See protein sequence)
Recommended Name: Zinc finger CCCH domain-containing protein 7B  
Size: 993 amino acids; 111578 Da
Subunit: Interacts (via LD motif) with rotavirus A NSP3 (via the coiled-coil region)
Secondary accessions: A7YY88 B2RCA4 Q5TFX9 Q8TBT9 Q9H8B6 Q9UGQ9 Q9UGR0 Q9UGR1 Q9UK03 Q9UPW9
Alternative splicing: 2 isoforms:  Q9UGR2-1   Q9UGR2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZC3H7B: NX_Q9UGR2

Explore proteomics data for ZC3H7B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys784
  • Modification sites at PhosphoSitePlus

  • See ZC3H7B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060060.3  
    ENSEMBL proteins: 
     ENSP00000345793   ENSP00000263243  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZC3H: Zinc fingers, CCCH-type domain containing
    TTC: Tetratricopeptide (TTC) repeat domain containing

    5 InterPro protein domains:
     IPR000571 Znf_CCCH
     IPR011990 TPR-like_helical
     IPR015880 Znf_C2H2-like
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9UGR2

    ProtoNet protein and cluster: Q9UGR2

    1 Blocks protein domain: IPB000571 Zn-finger

    UniProtKB/Swiss-Prot: Z3H7B_HUMAN, Q9UGR2
    Similarity: Contains 1 C2H2-type zinc finger
    Similarity: Contains 4 C3H1-type zinc fingers
    Similarity: Contains 3 TPR repeats


    Find genes that share domains with ZC3H7B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15047801
    GO:0044822poly(A) RNA binding IDA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZC3H7B           About GenesLikeMe


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target ZC3H7B:
    hsa-mir-877-3p (MIRT036862), hsa-mir-193a-5p (MIRT038605), hsa-mir-193b-3p (MIRT041480), hsa-mir-296-3p (MIRT038348), hsa-mir-421 (MIRT039423), hsa-mir-106b-3p (MIRT038598), hsa-mir-484 (MIRT042116)

    Block miRNA regulation of human, mouse, rat ZC3H7B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H7B (see all 111):
    hsa-miR-579 hsa-miR-323-3p hsa-miR-4254 hsa-miR-1914* hsa-miR-106a hsa-miR-1224-3p hsa-miR-3653 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H7B 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H7B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    Z3H7B_HUMAN, Q9UGR2: Nucleus. Note=Nuclear localization seems to be depleted upon rotavirus A infection
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZC3H7B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZC3H7B
    Interactions:

        Search GeneGlobe Interaction Network for ZC3H7B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    Selected Interacting proteins for ZC3H7B (Q9UGR21, 2, 3 ENSP000003457934) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2870822 I2D: score=3 STRING: ENSP00000244769
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    EIF4G1Q046373, ENSP000003168794I2D: score=1 STRING: ENSP00000316879
    FAM203AENSP000003213204STRING: ENSP00000321320
    FAM203BENSP000003666234STRING: ENSP00000366623
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016032viral process IEA--
    GO:0019048modulation by virus of host morphology or physiology ----

    Find genes that share ontologies with ZC3H7B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZC3H7B (Z3H7B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZC3H7B gene: 
    NM_017590.5  

    Unigene Cluster for ZC3H7B:

    Zinc finger CCCH-type containing 7B
    Hs.592188  [show with all ESTs]
    Unigene Representative Sequence: NM_017590
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000352645(uc003azw.3) ENST00000486331(uc003azv.1) ENST00000351589

    miRNA
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    Block miRNA regulation of human, mouse, rat ZC3H7B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H7B (see all 111):
    hsa-miR-579 hsa-miR-323-3p hsa-miR-4254 hsa-miR-1914* hsa-miR-106a hsa-miR-1224-3p hsa-miR-3653 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H7B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZC3H7B
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    GenScript: all cDNA clones in your preferred vector: ZC3H7B (NM_017590)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZC3H7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H7B
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      QuantiTect SYBR Green Assays in human, mouse, rat ZC3H7B
      QuantiFast Probe-based Assays in human, mouse, rat ZC3H7B

    Additional mRNA sequence: 

    AB028954.1 AF188530.1 AK021658.1 AK130876.1 AK225891.1 AK315009.1 AL136802.1 BC024313.2 
    BC047002.1 BC056860.1 BC098378.1 BC127840.1 BC152558.1 

    15 DOTS entries:

    DT.309578  DT.97793124  DT.120653885  DT.120653836  DT.100739744  DT.91749318  DT.95191635  DT.97842493 
    DT.40286943  DT.75108937  DT.120653844  DT.120653886  DT.95077466  DT.91749335  DT.95139385 

    Selected AceView cDNA sequences (see all 184):

    BE855831 BM762209 CN484543 BF514703 BE221224 AW572280 AW504643 BG177232 
    AW182888 AA935554 NM_017590 AA737525 AW499978 BU506783 CF995164 CN484544 
    BM712375 CR626766 CB988128 H55396 BC056860 BM478968 BQ052912 H55547 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H7B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:                                                  -                                         -           -           -                                       
    SP2:                                                                                                                                                            
    SP3:                                                                                            -                                                               
    SP4:                                                                                                        -                                                   
    SP5:                                                                                                                                                            

    ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for ZC3H7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZC3H7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGGCGGGGT
    ZC3H7B Expression
    About this image


    ZC3H7B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Blood (Cardiovascular System)
             Double Positive Thymocytes Thymus
    ZC3H7B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZC3H7B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592188
        Custom PCR Arrays for ZC3H7B
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat ZC3H7B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H7B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZC3H7B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zc3h7b1 , 5 zinc finger CCCH type containing 7B1, 5 90.43(n)1
    96.87(a)1
      15 (38.23 cM)5
    202861  NM_001081016.11  NP_001074485.11 
     817448485 
    chicken
    (Gallus gallus)
    Aves ZC3H7B1 zinc finger CCCH-type containing 7B 78.78(n)
    84.14(a)
      417996  XM_004937707.1  XP_004937764.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZC3H7B6
    zinc finger CCCH-type containing 7B
    75(a)
    1 ↔ 1
    5(26310133-26359937)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.121442 Xenopus laevis transcribed sequence with weak similarity more 74.48(n)    CD253715.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ZC3H7B (3 of 3)6
    zc3h7b6
    (see all 3)
    zinc finger CCCH-type containing 7B
    (see all 3)
    47(a)
    43(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    3(4774862-4780746) ENSDARG00000095045
    12(20252401-20282147) ENSDARG00000055930


    ENSEMBL Gene Tree for ZC3H7B (if available)
    TreeFam Gene Tree for ZC3H7B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZC3H7B gene
    ZC3H7A2  
    1 SIMAP similar gene for ZC3H7B using alignment to 2 protein entries:     Z3H7B_HUMAN (see all proteins):
    ZC3H7A

    Find genes that share paralogs with ZC3H7B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZC3H7B (see all 1248)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1410045641,2
    C--41695527(+) CTTGGC/TGTCCC 1 -- us2k10--------
    rs121574341,2
    C,F--41695636(+) AGAAGC/TGGTGG 1 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1139352051,2
    C,F--41695795(+) CTGTCA/G/TCCCAG 1 -- us2k12WA CSA 3
    rs1138574031,2
    C,F--41695893(+) TGGGAC/TTACAG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1417694161,2
    --41695900(+) ACAGGA/CTCCCG 1 -- us2k10--------
    rs1126450421,2
    C,F--41695912(+) CACCAC/TGCCCA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs412812831,2
    --41695972(+) GGATGG/TTCTCG 1 -- us2k10--------
    rs1863209201,2
    C--41696048(+) CCGCGC/GCCGGC 1 -- us2k10--------
    rs1911147021,2
    --41696345(+) TCGATG/TAAATG 1 -- us2k10--------
    rs60023221,2
    C--41696417(+) GCCTAA/GGGGGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZC3H7B (41697526 - 41756151 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ZC3H7B (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv507937CNV Insertion20534489
    nsv3638CNV Insertion18451855
    nsv915118CNV Loss21882294
    nsv915154CNV Loss21882294
    nsv834207CNV Loss17160897
    nsv915119CNV Loss21882294
    nsv915120CNV Loss21882294
    nsv915116CNV Loss21882294
    nsv524585CNV Loss19592680
    nsv516925CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZC3H7B           About GenesLikeMe

    Genetic Association Database (GAD): ZC3H7B
    Human Genome Epidemiology (HuGE) Navigator: ZC3H7B (1 document)

    Export disorders for ZC3H7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZC3H7B gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with ZC3H7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2, 3 Kikuno R.... Ohara O. (DNA Res. 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Nuclear localization of cytoplasmic poly(A)-binding protein upon rotavirus infection involves the interaction of NSP3 with eIF4G and RoXaN. (PubMed id 18799579)1, 2 Harb M.... Poncet D. (J. Virol. 2008)
    4. RoXaN, a novel cellular protein containing TPR, LD, and zinc finger motifs, forms a ternary complex with eukaryotic initiation factor 4G and rotavirus NSP3. (PubMed id 15047801)1, 2 Vitour D.... Poncet D. (J. Virol. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    9. Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22-translocation. (PubMed id 23580382)1 Panagopoulos I....Micci F. (amp 2013)
    10. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23264 HGNC: 30869 AceView: RoXaN Ensembl:ENSG00000100403 euGenes: HUgn23264
    ECgene: ZC3H7B H-InvDB: ZC3H7B

    (According to HUGE)
    About This Section

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    HUGE: KIAA1031

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZC3H7B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ZC3H7B gene:
    Search GeneIP for patents involving ZC3H7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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