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Aliases for ZC3H7A Gene

Aliases for ZC3H7A Gene

  • Zinc Finger CCCH-Type Containing 7A 2 3
  • Zinc Finger CCCH-Type Domain Containing 7 2 3
  • ZC3HDC7 3 4
  • ZC3H7 3 4
  • Zinc Finger CCCH Domain-Containing Protein 7A 3
  • Zinc Finger CCCH Type Domain Containing 7 3
  • Zinc Finger CCCH-Type Containing 7 2
  • Zinc-Finger Protein AY163807 3
  • HSPC055 3

External Ids for ZC3H7A Gene

Previous Symbols for ZC3H7A Gene

  • ZC3HDC7
  • ZC3H7

Summaries for ZC3H7A Gene

GeneCards Summary for ZC3H7A Gene

ZC3H7A (Zinc Finger CCCH-Type Containing 7A) is a Protein Coding gene. An important paralog of this gene is ZC3H7B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC3H7A Gene

Genomics for ZC3H7A Gene

Genomic Location for ZC3H7A Gene

Start:
11,750,586 bp from pter
End:
11,797,267 bp from pter
Size:
46,682 bases
Orientation:
Minus strand

Genomic View for ZC3H7A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC3H7A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC3H7A Gene

Regulatory Elements for ZC3H7A Gene

Proteins for ZC3H7A Gene

  • Protein details for ZC3H7A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWR0-Z3H7A_HUMAN
    Recommended name:
    Zinc finger CCCH domain-containing protein 7A
    Protein Accession:
    Q8IWR0
    Secondary Accessions:
    • D3DUG5
    • Q9NPE9

    Protein attributes for ZC3H7A Gene

    Size:
    971 amino acids
    Molecular mass:
    110538 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZC3H7A Gene

    Alternative splice isoforms for ZC3H7A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZC3H7A Gene

Proteomics data for ZC3H7A Gene at MOPED

Post-translational modifications for ZC3H7A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys425, Lys709, and Lys783

No data available for DME Specific Peptides for ZC3H7A Gene

Domains for ZC3H7A Gene

Gene Families for ZC3H7A Gene

HGNC:
  • TTC :Tetratricopeptide (TTC) repeat domain containing
  • ZC3H :Zinc fingers, CCCH-type domain containing

Protein Domains for ZC3H7A Gene

UniProtKB/Swiss-Prot:

Z3H7A_HUMAN
Similarity:
  • Contains 1 C2H2-type zinc finger.:
    • Q8IWR0
  • Contains 3 C3H1-type zinc fingers.:
    • Q8IWR0
  • Contains 3 TPR repeats.:
    • Q8IWR0
genes like me logo Genes that share domains with ZC3H7A: view

Function for ZC3H7A Gene

Gene Ontology (GO) - Molecular Function for ZC3H7A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZC3H7A: view

miRNA for ZC3H7A Gene

miRTarBase miRNAs that target ZC3H7A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZC3H7A Gene

Localization for ZC3H7A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZC3H7A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZC3H7A Gene COMPARTMENTS Subcellular localization image for ZC3H7A gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for ZC3H7A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZC3H7A: view

Pathways for ZC3H7A Gene

SuperPathways for ZC3H7A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZC3H7A Gene

None

No data available for Pathways by source for ZC3H7A Gene

Transcripts for ZC3H7A Gene

Unigene Clusters for ZC3H7A Gene

Zinc finger CCCH-type containing 7A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H7A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^
SP1: - - - - - - - - -
SP2: -
SP3: - - - - - - -
SP4: - - - - - -
SP5:
SP6: - -
SP7: - - - - -
SP8: - - - - -
SP9: - - - -
SP10: - - -
SP11: -
SP12:
SP13:
SP14:

ExUns: 16 ^ 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^ 21a · 21b ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b
SP1: -
SP2: -
SP3:
SP4:
SP5: - -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13:
SP14:

Relevant External Links for ZC3H7A Gene

GeneLoc Exon Structure for
ZC3H7A
ECgene alternative splicing isoforms for
ZC3H7A

Expression for ZC3H7A Gene

mRNA expression in normal human tissues for ZC3H7A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZC3H7A Gene

SOURCE GeneReport for Unigene cluster for ZC3H7A Gene Hs.371856

genes like me logo Genes that share expressions with ZC3H7A: view

Orthologs for ZC3H7A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZC3H7A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZC3H7A 36
  • 99.76 (n)
  • 99.59 (a)
ZC3H7A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZC3H7A 36
  • 90.77 (n)
  • 94.03 (a)
ZC3H7A 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZC3H7A 36
  • 92.28 (n)
  • 94.34 (a)
ZC3H7A 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zc3h7a 36
  • 87.16 (n)
  • 85.54 (a)
Zc3h7a 16
Zc3h7a 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZC3H7A 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 76 (a)
OneToMany
-- 37
  • 68 (a)
OneToMany
-- 37
  • 83 (a)
OneToMany
-- 37
  • 65 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zc3h7a 36
  • 86.03 (n)
  • 86.55 (a)
chicken
(Gallus gallus)
Aves ZC3H7A 36
  • 76.16 (n)
  • 74.33 (a)
ZC3H7A 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZC3H7A 37
  • 69 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13783 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11347 36
zc3h7a 36
  • 62.81 (n)
  • 57.34 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11063 36
zebrafish
(Danio rerio)
Actinopterygii wufa12e01 36
zc3h7a 36
  • 60.28 (n)
  • 55.8 (a)
zc3h7a 37
  • 51 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 37 (a)
OneToMany
Species with no ortholog for ZC3H7A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZC3H7A Gene

ENSEMBL:
Gene Tree for ZC3H7A (if available)
TreeFam:
Gene Tree for ZC3H7A (if available)

Paralogs for ZC3H7A Gene

Paralogs for ZC3H7A Gene

Selected SIMAP similar genes for ZC3H7A Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ZC3H7A: view

Variants for ZC3H7A Gene

Sequence variations from dbSNP and Humsavar for ZC3H7A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs7090 -- 11,750,799(-) ATGGG(G/T)TATTT utr-variant-3-prime
rs8743 -- 11,758,498(-) TATGT(G/T)GGAAA synonymous-codon, reference
rs759327 -- 11,760,116(-) ATTTT(A/T)TCTTG intron-variant
rs1014279 -- 11,758,699(-) ATTTA(C/G)AGCAT intron-variant
rs1062210 -- 11,759,834(-) TGCCC(A/G)GCCCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZC3H7A Gene

Variant ID Type Subtype PubMed ID
esv2674286 CNV Deletion 23128226
esv21664 CNV Loss 19812545

Relevant External Links for ZC3H7A Gene

HapMap Linkage Disequilibrium report
ZC3H7A

Disorders for ZC3H7A Gene

Relevant External Links for ZC3H7A

Genetic Association Database (GAD)
ZC3H7A
genes like me logo Genes that share disorders with ZC3H7A: view

No data available for UniProtKB/Swiss-Prot for ZC3H7A Gene

Publications for ZC3H7A Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Common variants at ten loci influence QT interval duration in the QTGEN Study. (PMID: 19305408) Newton-Cheh C. … Stricker B.H. (Nat. Genet. 2009) 3 49
  5. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3

Products for ZC3H7A Gene

Sources for ZC3H7A Gene

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