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Aliases for ZC3H6 Gene

Aliases for ZC3H6 Gene

  • Zinc Finger CCCH-Type Containing 6 2 3
  • Zinc Finger CCCH-Type Domain Containing 6 2 3
  • ZC3HDC6 3 4
  • Zinc Finger CCCH Domain-Containing Protein 6 3
  • Zinc Finger CCCH Type Domain Containing 6 3
  • KIAA2035 4

External Ids for ZC3H6 Gene

Previous HGNC Symbols for ZC3H6 Gene

  • ZC3HDC6

Previous GeneCards Identifiers for ZC3H6 Gene

  • GC02P112774
  • GC02P113033
  • GC02P105545

Summaries for ZC3H6 Gene

GeneCards Summary for ZC3H6 Gene

ZC3H6 (Zinc Finger CCCH-Type Containing 6) is a Protein Coding gene. An important paralog of this gene is ZC3H4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC3H6 Gene

Genomics for ZC3H6 Gene

Regulatory Elements for ZC3H6 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZC3H6 Gene

Start:
112,275,594 bp from pter
End:
112,340,063 bp from pter
Size:
64,470 bases
Orientation:
Plus strand

Genomic View for ZC3H6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC3H6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC3H6 Gene

Proteins for ZC3H6 Gene

  • Protein details for ZC3H6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P61129-ZC3H6_HUMAN
    Recommended name:
    Zinc finger CCCH domain-containing protein 6
    Protein Accession:
    P61129
    Secondary Accessions:
    • A9JR71
    • Q6ZW96

    Protein attributes for ZC3H6 Gene

    Size:
    1189 amino acids
    Molecular mass:
    131670 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC85608.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC87128.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC87128.1; Type=Frameshift; Positions=1120; Evidence={ECO:0000305};

neXtProt entry for ZC3H6 Gene

Proteomics data for ZC3H6 Gene at MOPED

Post-translational modifications for ZC3H6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZC3H6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZC3H6 Gene

Domains for ZC3H6 Gene

Gene Families for ZC3H6 Gene

HGNC:
  • ZC3H :Zinc fingers, CCCH-type domain containing

Protein Domains for ZC3H6 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZC3H6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P61129

UniProtKB/Swiss-Prot:

ZC3H6_HUMAN :
  • P61129
Similarity:
  • Contains 3 C3H1-type zinc fingers.
genes like me logo Genes that share domains with ZC3H6: view

Function for ZC3H6 Gene

Gene Ontology (GO) - Molecular Function for ZC3H6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZC3H6: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC3H6

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZC3H6 Gene

Localization for ZC3H6 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZC3H6 Gene COMPARTMENTS Subcellular localization image for ZC3H6 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZC3H6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ZC3H6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZC3H6 Gene

Pathways for ZC3H6 Gene

SuperPathways for ZC3H6 Gene

No Data Available

Interacting Proteins for ZC3H6 Gene

Gene Ontology (GO) - Biological Process for ZC3H6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZC3H6: view

No data available for Pathways by source for ZC3H6 Gene

Transcripts for ZC3H6 Gene

Unigene Clusters for ZC3H6 Gene

Zinc finger CCCH-type containing 6:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC3H6

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZC3H6

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H6 Gene

No ASD Table

Relevant External Links for ZC3H6 Gene

GeneLoc Exon Structure for
ZC3H6
ECgene alternative splicing isoforms for
ZC3H6

Expression for ZC3H6 Gene

mRNA expression in normal human tissues for ZC3H6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZC3H6 Gene

SOURCE GeneReport for Unigene cluster for ZC3H6 Gene Hs.190477

genes like me logo Genes that share expressions with ZC3H6: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZC3H6 Gene

Orthologs for ZC3H6 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZC3H6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZC3H6 35
  • 99.21 (n)
  • 98.98 (a)
ZC3H6 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZC3H6 35
  • 88.25 (n)
  • 85.79 (a)
ZC3H6 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZC3H6 35
  • 91.08 (n)
  • 88.59 (a)
ZC3H6 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zc3h6 35
  • 84.06 (n)
  • 77.62 (a)
Zc3h6 16
Zc3h6 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZC3H6 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZC3H6 36
  • 67 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zc3h6 35
  • 83.96 (n)
  • 77.42 (a)
chicken
(Gallus gallus)
Aves ZC3H6 35
  • 71.32 (n)
  • 67.52 (a)
ZC3H6 36
  • 65 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 59 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia zc3h6 35
  • 61.3 (n)
  • 54.32 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC559312 35
  • 54.35 (n)
  • 49.38 (a)
ZC3H8 36
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta su(s) 36
  • 10 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T26A8.4 36
  • 19 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4406 36
  • 21 (a)
OneToMany
Species with no ortholog for ZC3H6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZC3H6 Gene

ENSEMBL:
Gene Tree for ZC3H6 (if available)
TreeFam:
Gene Tree for ZC3H6 (if available)

Paralogs for ZC3H6 Gene

Paralogs for ZC3H6 Gene

genes like me logo Genes that share paralogs with ZC3H6: view

Variants for ZC3H6 Gene

Sequence variations from dbSNP and Humsavar for ZC3H6 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs4258804 -- 112,306,228(+) agtgc(A/G)gtggc intron-variant
rs4332934 -- 112,295,298(+) TGACT(A/G)AGGAA intron-variant
rs4352239 -- 112,325,706(-) GAAAG(G/T)TGTCC intron-variant
rs4392265 -- 112,283,438(+) GTTCC(A/G)AGTAG intron-variant
rs4399734 -- 112,314,911(-) ATACA(A/T)AGTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZC3H6 Gene

Variant ID Type Subtype PubMed ID
nsv521956 CNV Loss 19592680
nsv874863 CNV Loss 21882294
dgv4278n71 CNV Gain 21882294
nsv874867 CNV Loss 21882294
dgv4279n71 CNV Loss 21882294
nsv874871 CNV Gain 21882294
dgv4280n71 CNV Gain 21882294
nsv819303 CNV Gain 19587683
esv29391 CNV Gain 19812545
nsv829621 CNV Gain 20364138
esv2672162 CNV Deletion 23128226
nsv874876 CNV Loss 21882294
nsv819480 CNV Loss 19587683

Relevant External Links for ZC3H6 Gene

HapMap Linkage Disequilibrium report
ZC3H6
Human Gene Mutation Database (HGMD)
ZC3H6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZC3H6 Gene

Disorders for ZC3H6 Gene

(1) University of Copenhagen DISEASES for ZC3H6 Gene

genes like me logo Genes that share disorders with ZC3H6: view

No data available for UniProtKB/Swiss-Prot for ZC3H6 Gene

Publications for ZC3H6 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. (PMID: 24337577) Andresen C.A. … Flores-Morales A. (J. Biol. Chem. 2014) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ZC3H6 Gene

Sources for ZC3H6 Gene

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