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Aliases for ZC3H18 Gene

Aliases for ZC3H18 Gene

  • Zinc Finger CCCH-Type Containing 18 2 3
  • Nuclear Protein NHN1 3 4
  • NHN1 3 4
  • Zinc Finger CCCH Domain-Containing Protein 18 3
  • Conserved Nuclear Protein NHN1 3

External Ids for ZC3H18 Gene

Summaries for ZC3H18 Gene

GeneCards Summary for ZC3H18 Gene

ZC3H18 (Zinc Finger CCCH-Type Containing 18) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC3H18 Gene

Genomics for ZC3H18 Gene

Genomic Location for ZC3H18 Gene

Start:
88,570,381 bp from pter
End:
88,631,966 bp from pter
Size:
61,586 bases
Orientation:
Plus strand

Genomic View for ZC3H18 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC3H18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC3H18 Gene

Regulatory Elements for ZC3H18 Gene

Proteins for ZC3H18 Gene

  • Protein details for ZC3H18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86VM9-ZCH18_HUMAN
    Recommended name:
    Zinc finger CCCH domain-containing protein 18
    Protein Accession:
    Q86VM9
    Secondary Accessions:
    • Q96DG4
    • Q96MP7

    Protein attributes for ZC3H18 Gene

    Size:
    953 amino acids
    Molecular mass:
    106378 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZC3H18 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZC3H18 Gene

Proteomics data for ZC3H18 Gene at MOPED

Post-translational modifications for ZC3H18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZC3H18 Gene

No data available for DME Specific Peptides for ZC3H18 Gene

Domains for ZC3H18 Gene

Gene Families for ZC3H18 Gene

HGNC:
  • ZC3H :Zinc fingers, CCCH-type domain containing

Protein Domains for ZC3H18 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

ZCH18_HUMAN
Similarity:
  • Contains 1 C3H1-type zinc finger.:
    • Q86VM9
genes like me logo Genes that share domains with ZC3H18: view

Function for ZC3H18 Gene

Gene Ontology (GO) - Molecular Function for ZC3H18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZC3H18: view
genes like me logo Genes that share phenotypes with ZC3H18: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZC3H18 Gene

Localization for ZC3H18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZC3H18 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZC3H18 Gene COMPARTMENTS Subcellular localization image for ZC3H18 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZC3H18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZC3H18: view

Pathways for ZC3H18 Gene

SuperPathways for ZC3H18 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZC3H18 Gene

None

No data available for Pathways by source for ZC3H18 Gene

Transcripts for ZC3H18 Gene

Unigene Clusters for ZC3H18 Gene

Zinc finger CCCH-type containing 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H18 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b ^ 17 ^
SP1: -
SP2: -
SP3: - -
SP4:
SP5:
SP6: - -
SP7: - - - -
SP8: - - - - - - - - - - - - - -
SP9:
SP10:

ExUns: 18 ^ 19a · 19b ^ 20a · 20b
SP1: -
SP2:
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for ZC3H18 Gene

GeneLoc Exon Structure for
ZC3H18
ECgene alternative splicing isoforms for
ZC3H18

Expression for ZC3H18 Gene

mRNA expression in normal human tissues for ZC3H18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZC3H18 Gene

SOURCE GeneReport for Unigene cluster for ZC3H18 Gene Hs.93670

genes like me logo Genes that share expressions with ZC3H18: view

Orthologs for ZC3H18 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZC3H18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZC3H18 37
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZC3H18 36
  • 81.29 (n)
  • 83.58 (a)
ZC3H18 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZC3H18 36
  • 84.98 (n)
  • 88.95 (a)
ZC3H18 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zc3h18 36
  • 85.48 (n)
  • 90.93 (a)
Zc3h18 16
Zc3h18 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZC3H18 37
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZC3H18 37
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zc3h18 36
  • 85.67 (n)
  • 90.92 (a)
chicken
(Gallus gallus)
Aves ZC3H18 37
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZC3H18 37
  • 71 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.14309 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.20181 36
zebrafish
(Danio rerio)
Actinopterygii Dr.24473 36
zc3h18 37
  • 49 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG1677 37
  • 24 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 32 (a)
OneToOne
Species with no ortholog for ZC3H18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZC3H18 Gene

ENSEMBL:
Gene Tree for ZC3H18 (if available)
TreeFam:
Gene Tree for ZC3H18 (if available)

Paralogs for ZC3H18 Gene

Selected SIMAP similar genes for ZC3H18 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZC3H18: view

No data available for Paralogs for ZC3H18 Gene

Variants for ZC3H18 Gene

Sequence variations from dbSNP and Humsavar for ZC3H18 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs885157 -- 88,618,787(+) GGGTT(C/T)TCCCC intron-variant
rs885158 -- 88,618,549(+) AGCAG(C/T)CTGGC intron-variant
rs885159 -- 88,618,555(+) CTGGC(A/G)TCTGT intron-variant
rs899728 -- 88,577,597(-) TCGCC(C/T)TTCTC reference, synonymous-codon
rs936621 -- 88,577,049(-) GTCCC(C/T)ACTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZC3H18 Gene

Variant ID Type Subtype PubMed ID
nsv907226 CNV Loss 21882294
nsv907255 CNV Loss 21882294
nsv907264 CNV Loss 21882294
nsv833325 CNV Loss 17160897
esv2678436 CNV Deletion 23128226
esv28119 CNV Loss 19812545
nsv523859 CNV Gain 19592680
nsv907268 CNV Loss 21882294
dgv2977n71 CNV Loss 21882294
dgv2978n71 CNV Loss 21882294
dgv2979n71 CNV Loss 21882294
nsv907278 CNV Loss 21882294
nsv1926 CNV Insertion 18451855

Relevant External Links for ZC3H18 Gene

HapMap Linkage Disequilibrium report
ZC3H18

Disorders for ZC3H18 Gene

(1) University of Copenhagen DISEASES for ZC3H18 Gene

Relevant External Links for ZC3H18

Genetic Association Database (GAD)
ZC3H18
Human Genome Epidemiology (HuGE) Navigator
ZC3H18
genes like me logo Genes that share disorders with ZC3H18: view

No data available for UniProtKB/Swiss-Prot for ZC3H18 Gene

Publications for ZC3H18 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF. (PMID: 17579712) Hastings M.L. … Krainer A.R. (PLoS ONE 2007) 2 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for ZC3H18 Gene

Sources for ZC3H18 Gene

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