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Aliases & Descriptions for ZC3H14
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases FLJ11806 1 , 2 MGC26892 2 NY-REN-37 1 , 2 UKp68 1 , 2
Descriptions Renal carcinoma antigen NY-REN-37 3 nuclear protein UKp68 2 zinc finger CCCH-type containing 14 2
Search outside databases for aliases for ZC3H14 gene
Summaries for ZC3H14 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7 Function : Binds the polyadenosine RNA oligonucleotides
Genomic Location for ZC3H14
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the ZC3H14 gene Entrez Gene cytogenetic band: 14q31.3 Ensembl cytogenetic band: 14q31.3 HGNC cytogenetic band: 14q31.3 ZC3H14 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P088100:
(about GC identifiers )
Start:
88,099,067 bp from pter
End:
88,158,368 bp from pter
Size:
59,302 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000014.7 NT_026437.11 Proteins for ZC3H14
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7 (See
protein sequence )Recommended Name: Zinc finger CCCH domain-containing protein 14 Size : 736 amino acids; 82876 Da
Subcellular location : Nucleus
Sequence caution : Sequence=AAL83289.1; Type=Miscellaneous discrepancy; Note=Several sequencingerrors; Sequence=AAS90302.1; Type=Miscellaneous discrepancy; Note=Several sequencing errors;Sequence=AK021868; Type=Frameshift; Positions=199;
Secondary accessions : A8MY46 Q6MZU4 Q6PJ32 Q6PUI6 Q6PUI8 Q86TQ5 Q86TW0 Q86TW1 Q8NCT6 Q8NCZ3 Q8TDE2Q9HAC9 Q9Y5A0 Alternative splicing : 8 isoforms : Q6PJT7-1 Q6PJT7-2 Q6PJT7-3 Q6PJT7-4 Q6PJT7-5 Q6PJT7-6 Q6PJT7-7 Q6PJT7-8
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (6 alternative transcripts):
NP_001153575.1 NP_001153576.1 NP_079100.2 NP_997543.1 NP_997544.1 NP_997545.2 ENSEMBL proteins: ENSP00000377164 ENSP00000251038 ENSP00000307025 ENSP00000352250 ENSP00000338002 ENSP00000384682 ENSP00000377150 ENSP00000327176 ENSP00000370059 ENSP00000251037 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 1 Gene Ontology (GO) cellular component term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005634 nucleus
IEA --
About this table Antibodies for ZC3H14: Assays for ZC3H14:
Protein
Domains/ Families for ZC3H14(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q6PJT7 ProtoNet protein and cluster: Q6PJT7
1 Blocks protein family : IPB000571 Zn-finger UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7 Similarity : Belongs to the ZC3H14 familySimilarity : Contains 2 C3H1-type zinc fingers
Gene Function for ZC3H14
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5 ): BC027607 Applied Biosystems Silencer ® siRNAs for ZC3H14 Sigma-Aldrich siRNA for ZC3H14 Sigma-Aldrich shRNA for ZC3H14 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_024824                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_024824                                  untagged cDNA clones in CMV expression vector (see all 5 ): BC027607  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_024824 UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7 Function : Binds the polyadenosine RNA oligonucleotides
3 Gene Ontology (GO) molecular function terms (links to tree view) :
About this table
Pathways & Interactions for ZC3H14
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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1 Interacting protein for ZC3H14 (ENSP00000251038 3 ) via UniProtKB, MINT, and/or STRING About this table
Drugs & Compounds for ZC3H14 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for ZC3H14
Transcripts for ZC3H14(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
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siRNAs from Applied Biosystems ,
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shRNA from
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OriGene ,
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5 ): BC027607 Sigma-Aldrich siRNA for ZC3H14 Sigma-Aldrich shRNA for ZC3H14 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_024824 NM_207660 NM_207661 NM_207662
REFSEQ mRNAs for ZC3H14 gene (6 alternative transcripts): NM_001160103.1 NM_001160104.1 NM_024824.4 NM_207660.3 NM_207661.2 NM_207662.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_024824 NM_207660 NM_207661 NM_207662
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_024824                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_024824                                  untagged cDNA clones in CMV expression vector (see all 5 ): BC027607  
Additional cDNA sequence: AF086083.1 AF155107.1 AF474376.1 AK021868.1 AK090809.1 AK302136.1 AK303123.1 AK304275.1 AL359625.1 AL834215.1 AY578060.1 AY578061.1 AY578062.1 AY578063.1 BC011793.1 BC023641.2 BC027607.2 BC034274.1 BX248265.1 BX248281.1 BX248769.1 BX640716.1 BX640876.1
22 DOTS entries : DT.95187202 DT.95187208 DT.97808871 DT.99991930 DT.95187224 DT.100036903 DT.100791097 DT.101984724 DT.120750366 DT.95187756 DT.100036904 DT.40208088 DT.95187219 DT.95187225 DT.97847515 DT.100756450 DT.100786344 DT.100842122 DT.120750370 DT.92440508 DT.120750365 DT.91664110
24/348 AceView cDNA sequences (see all 348
):AI373666 AI143388 BE045438 CF242889 BC023641 AA741479 BG569535 BF477379 CA426551 AI201309 AU119634 AA455182 N67843 AA910410 BM855409 BM766255 BF131543 BX640716 AI090924 R92889 AA233647 CA866623 BQ427901 BX248769
highest scoring ESTs for ZC3H14 :AI561196 AA233551 AA233636 AA233647 AA233666 AA280736 AA443473 AA446535 AA448862 AA455182
Unigene Cluster for ZC3H14: Zinc finger CCCH-type containing 14 Hs.325846 [show with all ESTs ] Unigene Representative Sequence: NM_024824 GeneLoc Exon Structure 5/21 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H14 (see all 21
) ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d · 8e ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ SP1 :         -   -     -                               -   -   -     SP2 :           -     -                               -   -   -     SP3 :         -   -     -                               -   -   -   -   SP4 :                                             -   -   -     SP5 :                                                    
ExUns: 14a · 14b · 14c · 14d ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b · 17c · 17d ^ 18 ^ 19 ^ 20a · 20b · 20c SP1 :                 -       -             SP2 : -   -   -   -   -   -       -       -             SP3 : -   -   -   -   -   -       -       -             SP4 :                 -       -             SP5 : -   -   -   -   -   -       -       -            
About this scheme ECgene alternative splicing isoforms for ZC3H14 10 Ensembl transcripts including schematic representations : ENST00000393530
ENST00000251038
ENST00000302216
ENST00000359301
ENST00000336693
ENST00000406216
ENST00000393514
ENST00000318308
ENST00000380684
ENST00000353091
Expression for ZC3H14
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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ZC3H14 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for ZC3H14 1 / 2 / 3
7 probe-sets matching ZC3H14 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TACTGATGAASOURCE GeneReport for Unigene cluster: Hs.325846
Orthologs for ZC3H14
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for ZC3H14 gene from 5/9 species (see all 9
)
About this table Species with no ortholog for ZC3H14 ENSEMBL Gene Tree for ZC3H14 Paralogs for ZC3H14 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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SNPs/Variants for ZC3H14 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for ZC3H14 (up to first 250kb)
Disorders & Mutations for ZC3H14
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for ZC3H14 (Possibly Related Articles in
Doctor's Guide )
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Publications for ZC3H14 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10/15 PubMed articles for ZC3H14 gene (see all 15
):
Search for ZC3H14
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZC3H14
(According to
Entrez Gene ,
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AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing ZC3H14
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Specialized Databases showing ZC3H14 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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