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ZC3H14 Gene

protein-coding   GIFtS: 47
GCID: GC14P089029

Zinc Finger CCCH-Type Containing 14

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger CCCH-Type Containing 141 2     NY-REN-372
Mammalian Suppressor Of Tau Pathology-22 3     UKp682
Renal Carcinoma Antigen NY-REN-372 3     Nuclear Protein UKp682
MSUT-22 3     Zinc Finger CCCH Domain-Containing Protein 142
SUT22 5     

External Ids:    HGNC: 205091   Entrez Gene: 798822   Ensembl: ENSG000001007227   OMIM: 6132795   UniProtKB: Q6PJT73   

Export aliases for ZC3H14 gene to outside databases

Previous GC identifers: GC14P088100 GC14P069199


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZC3H14 Gene:
ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA
stability, nuclear export, and translation (Kelly et al., 2007 (PubMed 17630287)).(supplied by OMIM, Mar 2010)

GeneCards Summary for ZC3H14 Gene:
ZC3H14 (zinc finger CCCH-type containing 14) is a protein-coding gene. Diseases associated with ZC3H14 include mental retardation, autosomal recessive 2, and tauopathy. GO annotations related to this gene include RNA binding.

UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7
Function: Binds the polyadenosine RNA oligonucleotides




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the ZC3H14 gene promoter:
         Max1   AP-1   ITF-2   Tal-1beta   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ZC3H14 promoter sequence
   Search Chromatin IP Primers for ZC3H14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZC3H14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q31.3   Ensembl cytogenetic band:  14q31.3   HGNC cytogenetic band: 14q31.3

ZC3H14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZC3H14 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P089029:  view genomic region     (about GC identifiers)

Start:
89,029,253 bp from pter      End:
89,079,853 bp from pter
Size:
50,601 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7 (See protein sequence)
Recommended Name: Zinc finger CCCH domain-containing protein 14  
Size: 736 amino acids; 82876 Da
Subunit: Interacts with HOOK2
Sequence caution: Sequence=AAL83289.1; Type=Miscellaneous discrepancy; Note=Several sequencing errors;
Sequence=AAS90302.1; Type=Frameshift; Positions=Several; Sequence=AAS90302.1; Type=Miscellaneous discrepancy;
Note=Aberrant splicing; Sequence=AK021868; Type=Frameshift; Positions=199; Sequence=CAE45933.1;
Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: A8MY46 B4E2H4 G3V5R4 Q6MZU4 Q6PJ32 Q6PUI6 Q6PUI8 Q86TQ5 Q86TW0 Q86TW1
Q8NCT6 Q8NCZ3 Q8TDE2 Q9HAC9 Q9Y5A0
Alternative splicing: 8 isoforms:  Q6PJT7-1   Q6PJT7-2   Q6PJT7-3   Q6PJT7-4   Q6PJT7-5   Q6PJT7-6   Q6PJT7-8   Q6PJT7-9   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZC3H14: NX_Q6PJT7

Explore proteomics data for ZC3H14 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys99, Lys139, Lys245, Lys283, Lys368, Lys378, Lys413, Lys489, Lys623, Lys728
  • Modification sites at PhosphoSitePlus

  • See ZC3H14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001153575.1  NP_001153576.1  NP_079100.2  NP_997543.1  NP_997544.1  NP_997545.2  

    ENSEMBL proteins: 
     ENSP00000251038   ENSP00000307025   ENSP00000451638   ENSP00000450917   ENSP00000450474  
     ENSP00000451389   ENSP00000452370   ENSP00000451489   ENSP00000452475   ENSP00000377150  
     ENSP00000338002   ENSP00000452210   ENSP00000450451   ENSP00000451054   ENSP00000451007  
     ENSP00000327176   ENSP00000451530   ENSP00000384682   ENSP00000451941   ENSP00000450823  
     ENSP00000352250  

    ZC3H14 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZC3H: Zinc fingers, CCCH-type domain containing

    1 InterPro protein domain:
     IPR000571 Znf_CCCH

    Graphical View of Domain Structure for InterPro Entry Q6PJT7

    ProtoNet protein and cluster: Q6PJT7

    1 Blocks protein domain: IPB000571 Zn-finger

    UniProtKB/Swiss-Prot: ZC3HE_HUMAN, Q6PJT7
    Similarity: Belongs to the ZC3H14 family
    Similarity: Contains 5 C3H1-type zinc fingers


    ZC3H14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZC3HE_HUMAN, Q6PJT7
    Function: Binds the polyadenosine RNA oligonucleotides

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0005515protein binding IPI19273536
    GO:0044822poly(A) RNA binding IDA--
    GO:0046872metal ion binding IEA--
         
    ZC3H14 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZC3H14
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZC3H14
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    miRNA
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    miRTarBase miRNAs that target ZC3H14:
    hsa-mir-769-5p (MIRT039156)

    Block miRNA regulation of human, mouse, rat ZC3H14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H14 (see all 23):
    hsa-miR-3149 hsa-miR-3689b hsa-miR-148b* hsa-miR-607 hsa-miR-4251 hsa-miR-520d-5p hsa-miR-3942-5p hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZC3H14

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    GenScript: all cDNA clones in your preferred vector (see all 6): ZC3H14 (NM_024824)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZC3H14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H14

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZC3HE_HUMAN, Q6PJT7: Nucleus speckle
    ZC3HE_HUMAN, Q6PJT7: Isoform 1: Nucleus speckle
    ZC3HE_HUMAN, Q6PJT7: Isoform 3: Nucleus speckle
    ZC3HE_HUMAN, Q6PJT7: Isoform 6: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0016607nuclear speck IEA--

    ZC3H14 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZC3H14
    Interactions:

        Search GeneGlobe Interaction Network for ZC3H14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZC3H14 (Q6PJT72, 3 ENSP000002510384) via UniProtKB, MINT, STRING, and/or I2D (see all 1040)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRT20P359002, 3, ENSP000001675884MINT-67243 I2D: score=5 STRING: ENSP00000167588
    SRRM1Q8IYB33, ENSP000003262614I2D: score=1 STRING: ENSP00000326261
    EXOC7Q9UPT53, ENSP000003341004I2D: score=4 STRING: ENSP00000334100
    TPRENSP000003564484STRING: ENSP00000356448
    EXOSC10ENSP000003661354STRING: ENSP00000366135
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZC3H14 (ZC3HE)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZC3H14 gene (6 alternative transcripts): 
    NM_001160103.1  NM_001160104.1  NM_024824.4  NM_207660.3  NM_207661.2  NM_207662.3  

    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000251038(uc001xww.3 uc010twd.2 uc010twe.2 uc001xwx.3 uc010twf.2 uc001xwy.3 uc010twg.2 uc001xxa.3 uc001xxc.3 uc001xxb.3)
    ENST00000302216 ENST00000554602 ENST00000553495 ENST00000556945 ENST00000556158
    ENST00000557607 ENST00000555799 ENST00000555755 ENST00000393514 ENST00000336693
    ENST00000557693 ENST00000555120 ENST00000556000 ENST00000557605 ENST00000556110
    ENST00000557047 ENST00000318308
    miRNA
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    Block miRNA regulation of human, mouse, rat ZC3H14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H14 (see all 23):
    hsa-miR-3149 hsa-miR-3689b hsa-miR-148b* hsa-miR-607 hsa-miR-4251 hsa-miR-520d-5p hsa-miR-3942-5p hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZC3H14
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    GenScript: all cDNA clones in your preferred vector (see all 6): ZC3H14 (NM_024824)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H14
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZC3H14
      QuantiTect SYBR Green Assays in human, mouse, rat ZC3H14
      QuantiFast Probe-based Assays in human, mouse, rat ZC3H14

    Selected AceView cDNA sequences (see all 348):

    BM766255 BF131543 H90342 BC023641 H90382 BE045438 CF242889 BM988449 
    BG569535 N67843 AI681400 AA280736 R92889 BQ427901 AL834215 BX344589 
    BM855409 AA364183 NM_207660 CB141209 AK090809 AI090924 BX345661 BU175978 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H14 (see all 21)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d · 8e ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^
    SP1:                          -     -           -                                                                                         -     -     -         
    SP2:                                -           -                                                                                         -     -     -         
    SP3:                          -     -           -                                                                                         -     -     -     -   
    SP4:                                                                                                                                      -     -     -         
    SP5:                                                                                                                                                            

    ExUns: 14a · 14b · 14c · 14d ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b · 17c · 17d ^ 18 ^ 19 ^ 20a · 20b · 20c
    SP1:                                                  -                 -                                 
    SP2:  -     -     -     -     -     -                 -                 -                                 
    SP3:  -     -     -     -     -     -                 -                 -                                 
    SP4:                                                  -                 -                                 
    SP5:  -     -     -     -     -     -                 -                 -                                 


    ECgene alternative splicing isoforms for ZC3H14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZC3H14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACTGATGAA
    ZC3H14 Expression
    About this image

    ZC3H14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZC3H14 Protein Expression
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    QuantiFast Probe-based Assays in human, mouse, rat ZC3H14
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZC3H14 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zc3h141 , 5 zinc finger CCCH type containing 141, 5 90.61(n)1
    89.93(a)1
      12 (49.88 cM)5
    755531  NM_029334.21  NP_083610.21 
     987469685 
    chicken
    (Gallus gallus)
    Aves ZC3H141 zinc finger CCCH-type containing 14 72.23(n)
    71.72(a)
      423399  NM_001012586.2  NP_001012604.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZC3H146
    zinc finger CCCH-type containing 14
    68(a)
    1 ↔ 1
    1(13547708-13580895)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.239692 Xenopus laevis transcribed sequence with moderate similarity more 77.17(n)    BJ095425.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.135702 Transcribed sequence with weak similarity to protein more 74.42(n)    BM316027.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nab26
    --
    20(a)
    1 ↔ 1
    3R(20140382-20144142)
    worm
    (Caenorhabditis elegans)
    Secernentea sut-26
    Protein SUT-2 (sut-2) mRNA, complete cds
    20(a)
    1 ↔ 1
    V(4562215-4570043) WBGene00022019


    ENSEMBL Gene Tree for ZC3H14 (if available)
    TreeFam Gene Tree for ZC3H14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZC3H14 gene

    ZC3H14 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ZC3H14
    PGOHUM00000235161 PGOHUM00000243298


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZC3H14 (see all 1146)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1481786341,2
    C--89027429(+) GGAAG-/ACACACA 4 -- us2k10--------
    rs1421400091,2
    --89027483(+) AATAGC/GTTCCA 4 -- us2k10--------
    rs617413991,2
    C,F--89027544(+) GACCAC/TGTGAC 4 -- us2k13Minor allele frequency- T:0.06NS CSA WA 198
    rs1511838571,2
    --89027549(+) CGTGAC/TAGACC 4 -- us2k10--------
    rs1403092981,2
    --89027553(+) ACAGAC/TCCTAG 4 -- us2k10--------
    rs1880648341,2
    --89027594(+) CCACAA/TCCCAC 4 -- us2k10--------
    rs1503674941,2
    --89027658(+) TTTGGC/TAGATG 4 -- us2k10--------
    rs744594751,2
    F--89027660(+) TGGCAG/TATGTA 4 -- us2k11Minor allele frequency- T:0.05NA 120
    rs1117153301,2
    C--89027740(+) CTTGGCTGGTCTC
    AAACTT
    /-
    CTGGT
    5 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1169186231,2
    C,F--89027811(+) ATGAGC/TCACTG 5 -- us2k11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for ZC3H14 (89029253 - 89079853 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZC3H14:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2748997CNV Deletion23290073
    esv2748994CNV Deletion23290073
    esv2748995CNV Deletion23290073
    nsv820243CNV Gain19587683
    nsv902181CNV Gain21882294
    nsv456391CNV Gain19166990

    Human Gene Mutation Database (HGMD): ZC3H14
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ZC3H14
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613279    OMIM disorders: --

    5 diseases for ZC3H14:    About MalaCards
    mental retardation, autosomal recessive 2    tauopathy    intellectual disability    renal cell carcinoma
    malaria


    ZC3H14 for disorders           About GeneDecksing


    Export disorders for ZC3H14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZC3H14 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with ZC3H14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2, 3 Scanlan M.J....Old L.J. (Int. J. Cancer 1999)
    2. Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein. (PubMed id 19303045)1, 2 Leung S.W.... Corbett A.H. (Gene 2009)
    3. SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. (PubMed id 19273536)1, 2 Guthrie C.R.... Kraemer B.C. (Hum. Mol. Genet. 2009)
    4. Recognition of polyadenosine RNA by zinc finger proteins. (PubMed id 17630287)1, 2 Kelly S.M.... Berland K.M. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79882 HGNC: 20509 AceView: FLJ11806 Ensembl:ENSG00000100722 euGenes: HUgn79882
    ECgene: ZC3H14 H-InvDB: ZC3H14

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZC3H14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZC3H14 gene:
    Search GeneIP for patents involving ZC3H14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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