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Aliases & Descriptions for ZC3H13
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| DKFZp434D1812 1, 2 | | FLJ35669 2 | | KIAA0853 1, 2, 3 | | OTTHUMP00000018357 2 |
| | | Descriptions |
|---|
| zinc finger CCCH-type containing 13 2 |
|
| | Search outside databases for aliases for ZC3H13 gene |
Summaries for ZC3H13(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Gene Wiki entry for ZC3H13 |
Genomic Location for ZC3H13
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the ZC3H13 gene 
Entrez Gene cytogenetic band: 13q14.12 Ensembl cytogenetic band: 13q14.12 HGNC cytogenetic band: 13q14.11ZC3H13 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M045426:
(about GC identifiers)
Start:
|
45,426,601 bp from pter |
End:
|
45,524,895 bp from pter |
Size:
|
98,295 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000013.9 NT_024524.13
| Proteins for ZC3H13
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: ZC3HD_HUMAN, Q5T200 (See
protein sequence)Recommended Name: Zinc finger CCCH domain-containing protein 13 Size: 1668 amino acids; 196635 Da
Secondary accessions: A2A323 O94936 Q5T1Z9 Q7Z7J3 Q8NDT6 Q9H0L6Alternative splicing: 2 isoforms: Q5T200-1 Q5T200-2 Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_055885.3
ENSEMBL proteins: ENSP00000368201 ENSP00000242848 ENSP00000282007
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for ZC3H13: Assays for ZC3H13: | Protein
Domains/ Families for ZC3H13(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q5T200
ProtoNet protein and cluster: Q5T200 1 Blocks protein family: IPB000571 Zn-finger
UniProtKB/Swiss-Prot: ZC3HD_HUMAN, Q5T200Similarity: Contains 1 C3H1-type zinc finger | Gene Function for ZC3H13
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC019000
Applied Biosystems Silencer® siRNAs for ZC3H13
Sigma-Aldrich siRNA for ZC3H13  Sigma-Aldrich shRNA for ZC3H13  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_015070                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_015070                                  untagged cDNA clones in CMV expression vector (see all 3): AK001815 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_015070
3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for ZC3H13
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Interacting protein for ZC3H13 (Q5T2002) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds for ZC3H13(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for ZC3H13
|
Transcripts for ZC3H13(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC019000
Sigma-Aldrich siRNA for ZC3H13  Sigma-Aldrich shRNA for ZC3H13  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_015070 REFSEQ mRNAs for ZC3H13 gene: NM_015070.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_015070               OriGene GFP tagged cDNA clone in CMV expression vector: NM_015070                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_015070                                  untagged cDNA clones in CMV expression vector (see all 3): AK001815  Additional cDNA sequence: AB020660.1 AK001815.1 AK056422.1 AK074924.1 AK092988.1 AL136745.1 AL831833.1 AY283618.1 BC019000.2 BC032425.1 BC050658.2 BC062685.1 BC107864.1 22 DOTS entries: DT.65284215 DT.455108 DT.110411 DT.95258392 DT.92352302 DT.92418508 DT.100813404 DT.407461 DT.407460 DT.92436998 DT.100813397 DT.100813401 DT.120791108 DT.40274428 DT.92326246 DT.92413573 DT.95359816 DT.97799374 DT.100813399 DT.91747216 DT.95345320 DT.97858505 24/309 AceView cDNA sequences (see all 309
):BU186837 BE551563 AA885613 AI088551 BG943739 BM699307 BM504539 BE766369 N50717 BG942948 AA588518 AA807559 NM_015070 AB020660 AA604101 BG943281 AW629264 BG942236 BG114807 CA393684 BC050658 AI695267 BX956136 AW237833
highest scoring ESTs for ZC3H13:AB020660 AI472196 AK056422 AY283618 BE247416 BF107255 BF681397 BI090938 BX504090 CA393684 Unigene Cluster for ZC3H13: Zinc finger CCCH-type containing 13 Hs.136102 [show with all ESTs]Unigene Representative Sequence: AY283618
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H13 (see all 9
)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24 | |
| SP1: | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for ZC3H13
3 Ensembl transcripts including schematic representations: ENST00000378921
ENST00000242848
ENST00000282007
|
Expression for ZC3H13
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ZC3H13 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ZC3H13
1 / 2 / 3 9 probe-sets matching ZC3H13 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.136102
|
Orthologs for ZC3H13
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZC3H13 gene from 5/13 species (see all 13
)
About this table Species with no ortholog for ZC3H13
ENSEMBL Gene Tree for ZC3H13 | Paralogs for ZC3H13(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for ZC3H13(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ZC3H13 (up to first 250kb)
|
Disorders & Mutations for ZC3H13
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for ZC3H13(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for ZC3H13 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/18 PubMed articles for ZC3H13 gene (see all 18
):- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)2, 3, 4 Nagase T....Ohara O. (1998)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)3, 4 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)3, 4 Olsen J.V....Mann M. (2006)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)3, 4 Dunham A.... Ross M.T. (2004)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)3, 4 Brill L.M....Peters E.C. (2004)
- Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)3, 4 Beausoleil S.A....Gygi S.P. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)3, 4 Wiemann S.... Poustka A. (2001)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)4 Cantin G.T....Yates J.R. III (2008)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)4 Daub H.... Mann M. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)4 Dephoure N.... Gygi S.P. (2008)
|
Search for ZC3H13
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZC3H13
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ZC3H13
(According to HUGE)
About This Section
| |
Specialized Databases showing ZC3H13(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for ZC3H13(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for ZC3H13:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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