ZC3H11A Gene
protein-coding GIFtS: 51
GCID: GC01P203765
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zinc finger CCCH-type containing 11A(Previous name: zinc finger CCCH-type domain containing 11A )
(Previous symbol: ZC3HDC11A)
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Aliases
for ZC3H11A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger CCCH-Type Containing 11A1 2 | | Zinc Finger CCCH Domain-Containing Protein 11A2 | | ZC3HDC11A1 2 3 | | EC 4.1.1.318 | | KIAA06631 3 5 | | EC 4.2.1.118 | | Zinc Finger CCCH-Type Domain Containing 11A1 2 | | |
Export aliases for ZC3H11A gene to outside databasesPrevious GC identifers: GC01P200497 GC01P202031 GC01P174930 |
Summaries
for ZC3H11A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for ZC3H11A
|
Genomic Views
for ZC3H11A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZC3H11A gene promoter:
MEF-2 CUTL1 Cdc5 HNF-1A AREB6 MEF-2A HNF-1 aMEF-2 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZC3H11A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZC3H11A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32.1 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32.1ZC3H11A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P203765: view genomic region
(about GC identifiers)
Start:
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203,764,751 bp from pter |
End:
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203,823,256 bp from pter |
Size:
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58,506 bases |
Orientation:
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plus strand |
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Proteins
for ZC3H11A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZC11A_HUMAN, O75152 (See
protein sequence)Recommended Name: Zinc finger CCCH domain-containing protein 11A Size: 810 amino acids; 89131 Da
Sequence caution: Sequence=BAA31638.2; Type=Erroneous initiation; Sequence=CAH10553.1; Type=Miscellaneous discrepancy;Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: Q6AHY4 Q6AHY9 Q6AW79 Q6AWA1 Q6PJK4 Q86XZ7Explore the universe of human proteins at neXtProt for ZC3H11A: NX_O75152
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75152
2 DME Specific Peptides for ZC3H11A (O75152)
ZC3H11A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055642.3
ENSEMBL proteins: ENSP00000406531 ENSP00000415072 ENSP00000356183 ENSP00000356181 ENSP00000333253 ENSP00000432602 ENSP00000356179 ENSP00000438527
Human Recombinant Protein Products:
ZC3H11A Antibody Products:
Assay Products for ZC3H11A: |
Protein
Domains /
Families
for ZC3H11A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZC3H11A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75152ProtoNet protein and cluster: O75152 1 Blocks protein family: IPB000571 Zn-finger
UniProtKB/Swiss-Prot: ZC11A_HUMAN, O75152Similarity: Contains 3 C3H1-type zinc fingers |
Function
for ZC3H11A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Enzyme Numbers (IUBMB): EC 4.1.1.312 EC 4.2.1.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H11A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H11A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H11A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZC3H11A for ontologies About GeneDecksing
|
Pathways & Interactions
for ZC3H11A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZC3H11A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/35 Interacting proteins for ZC3H11A (O751521, 2, 3 ENSP000003332534) via UniProtKB, MINT, STRING, and/or I2D (see all 35)About this table
|
Drugs & Compounds
for ZC3H11A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZC3H11A
Search CenterWatch for drugs/clinical trials and news about ZC3H11A / ZC11A
|
Transcripts
for ZC3H11A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZC3H11A gene: NM_014827.4 Unigene Cluster for ZC3H11A: Zinc finger CCCH-type containing 11A Hs.532399 [show with all ESTs]Unigene Representative Sequence: CR62743913 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000466470 ENST00000432282 ENST00000453771 ENST00000461980 ENST00000367214
ENST00000492823 ENST00000367212(uc001hag.1) ENST00000332127(uc001hac.3 uc001had.3 uc001hae.3 uc010pqm.2)
ENST00000495527 ENST00000367210 ENST00000480354 ENST00000488411 ENST00000545588(uc001haf.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H11A (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H11A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZC3H11A (NM_014827) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZC3H11A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H11A |
Additional cDNA sequence: AB014563.1 AK095858.1 AK296983.1 AK310470.1 AL049419.1 BC014268.2 BC038513.2 BC046137.2 BC048271.1 CR627439.1 24/49 DOTS entries (see all 49): DT.319879 DT.99941762 DT.121452670 DT.100802807 DT.91757416 DT.95368226 DT.92024926 DT.101984844 DT.121452760 DT.95234065 DT.319880 DT.121452703 DT.100689774 DT.100825692 DT.121419632 DT.121419635 DT.121452692 DT.95234119 DT.121452745 DT.121452748 DT.91836429 DT.92414049 DT.95156707 DT.95157215 24/540 AceView cDNA sequences (see all 540): BU542936 AA454142 AL041677 AI803216 BM973370 BQ774787 AI193446 BU521292 BX470522 AA903135 BM556867 CA415029 NM_014827 CN478993 AW292854 BU615369 CA419266 CB157734 BX350111 AA804853 AF086224 AW295659 AA318373 BM801763
GeneLoc Exon Structure
|
Expression
for ZC3H11A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZC3H11A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATTTTCTAC
About this image
See ZC3H11A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZC3H11A
SOURCE GeneReport for Unigene cluster: Hs.532399
SABiosciences Custom PCR Arrays for ZC3H11A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZC3H11A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZC3H11A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZC3H11A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZC3H11A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H11A |
Orthologs
for ZC3H11A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZC3H11A gene from 5/16 species (see all 16) About this table
ENSEMBL Gene Tree for ZC3H11A (if available)
TreeFam Gene Tree for ZC3H11A (if available) |
Paralogs
for ZC3H11A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZC3H11A gene
- C12orf502
1 SIMAP similar gene for ZC3H11A using alignment to 5 protein entries: ZC11A_HUMAN (see all proteins):C12orf50
ZC3H11A for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZC3H11A
PGOHUM00000244423 PGOHUM00000243660
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Genomic Variants
for ZC3H11A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZC3H11A (203764751 - 203823256 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZC3H11A
2 CNVs: 48233 48232 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZC3H11A |
|
Disorders
/ Diseases
for ZC3H11A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZC3H11A for disorders About GeneDecksing
OMIM gene information: 613513
OMIM disorders: --
3  diseases for ZC3H11A: About MalaCardsessential hypertension myopia hypertension
Human Genome Epidemiology (HuGE) Navigator: ZC3H11A (1 document)
Export disorders for ZC3H11A gene to outside databases
|
Publications
for ZC3H11A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZC3H11A gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with ZC3H11A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
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External Searches for ZC3H11A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZC3H11A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZC3H11A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZC3H11A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZC3H11A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZC3H11A gene:
Search GeneIP for patents involving ZC3H11A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZC3H11A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZC3H11A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZC3H11A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZC3H11A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZC3H11A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZC3H11A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZC3H11A |
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 | | | ZC3H11A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H11A |
|  |  |  | | | | Search ThermoFisher Antibodies for ZC3H11A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H11A |
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