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ZC3H11A Gene

protein-coding   GIFtS: 54
GCID: GC01P203765

Zinc Finger CCCH-Type Containing 11A

(Previous name: zinc finger CCCH-type domain containing 11A)
(Previous symbol: ZC3HDC11A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger CCCH-Type Containing 11A1 2     Zinc Finger CCCH Domain-Containing Protein 11A2
ZC3HDC11A1 2 3     EC 4.1.1.318
Zinc Finger CCCH-Type Domain Containing 11A1 2     EC 4.2.1.118
KIAA06633 5     

External Ids:    HGNC: 290931   Entrez Gene: 98772   Ensembl: ENSG000000586737   OMIM: 6135135   UniProtKB: O751523   

Export aliases for ZC3H11A gene to outside databases

Previous GC identifers: GC01P200497 GC01P202031 GC01P174930


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZC3H11A Gene:
ZC3H11A (zinc finger CCCH-type containing 11A) is a protein-coding gene. Diseases associated with ZC3H11A include myopia, and essential hypertension.

UniProtKB/Swiss-Prot: ZC11A_HUMAN, O75152
Function: Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex

Gene Wiki entry for ZC3H11A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZC3H11A gene promoter:
         MEF-2   CUTL1   Cdc5   HNF-1A   AREB6   MEF-2A   HNF-1   aMEF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZC3H11A promoter sequence
   Search Chromatin IP Primers for ZC3H11A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZC3H11A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32.1

ZC3H11A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZC3H11A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P203765:  view genomic region     (about GC identifiers)

Start:
203,764,751 bp from pter      End:
203,823,256 bp from pter
Size:
58,506 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZC11A_HUMAN, O75152 (See protein sequence)
Recommended Name: Zinc finger CCCH domain-containing protein 11A  
Size: 810 amino acids; 89131 Da
Subunit: Interacts with THOC2, DDX39 and POLDIP3; the interactions are ATP-dependent and indicative for an
association with the TREX complex
Sequence caution: Sequence=BAA31638.2; Type=Erroneous initiation; Sequence=CAH10553.1; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: Q6AHY4 Q6AHY9 Q6AW79 Q6AWA1 Q6PJK4 Q86XZ7

Explore the universe of human proteins at neXtProt for ZC3H11A: NX_O75152

Explore proteomics data for ZC3H11A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for ZC3H11A (O75152)
     LTERLGK  AAQTLEK 


    See ZC3H11A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055642.3  
    ENSEMBL proteins: 
     ENSP00000406531   ENSP00000415072   ENSP00000356183   ENSP00000356181   ENSP00000333253  
     ENSP00000432602   ENSP00000356179   ENSP00000438527  

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    Cloud-Clone Corp. Proteins for ZC3H11A

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZC3H: Zinc fingers, CCCH-type domain containing

    1 InterPro protein domain:
     IPR000571 Znf_CCCH

    Graphical View of Domain Structure for InterPro Entry O75152

    ProtoNet protein and cluster: O75152

    1 Blocks protein domain: IPB000571 Zn-finger

    UniProtKB/Swiss-Prot: ZC11A_HUMAN, O75152
    Similarity: Contains 3 C3H1-type zinc fingers


    ZC3H11A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZC11A_HUMAN, O75152
    Function: Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex

         Enzyme Numbers (IUBMB): EC 4.1.1.312 EC 4.2.1.112

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
    GO:0044822poly(A) RNA binding IDA--
    GO:0046872metal ion binding IEA--
         
    ZC3H11A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZC3H11A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZC3H11A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZC3H11A

    miRNA
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    miRTarBase miRNAs that target ZC3H11A:
    hsa-mir-27b-3p (MIRT046201), hsa-mir-335-5p (MIRT017449), hsa-mir-16-5p (MIRT031561), hsa-mir-1 (MIRT023668), hsa-let-7b-5p (MIRT032296)

    Block miRNA regulation of human, mouse, rat ZC3H11A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H11A (see all 37):
    hsa-miR-3685 hsa-miR-607 hsa-miR-4328 hsa-miR-15a hsa-miR-503 hsa-miR-374c hsa-miR-424 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H11A 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H11A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton3
    nucleus3
    plasma membrane3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000346colocalizes with transcription export complex IDA--

    ZC3H11A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZC3H11A
    Interactions:

        Search GeneGlobe Interaction Network for ZC3H11A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for ZC3H11A (O751521, 2, 3 ENSP000003332534) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MLH1P406921, 2, 3, ENSP000002317904EBI-748480,EBI-744248 MINT-67298 I2D: score=5 STRING: ENSP00000231790
    SUMO1P631652, 3, ENSP000003760764MINT-8173832 I2D: score=1 STRING: ENSP00000376076
    BEND3Q5T5X72MINT-8173832
    CHAMP1Q96JM32MINT-8173832
    CTPS1P178122MINT-8173832
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016973poly(A)+ mRNA export from nucleus IMP--

    ZC3H11A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZC3H11A (ZC11A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZC3H11A gene: 
    NM_014827.4  

    Unigene Cluster for ZC3H11A:

    Zinc finger CCCH-type containing 11A
    Hs.532399  [show with all ESTs]
    Unigene Representative Sequence: CR627439
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000466470 ENST00000432282 ENST00000453771 ENST00000461980 ENST00000367214
    ENST00000492823 ENST00000367212(uc001hag.1) ENST00000332127(uc001hac.3 uc001had.3 uc001hae.3 uc010pqm.2)
    ENST00000495527 ENST00000367210 ENST00000480354 ENST00000488411 ENST00000545588(uc001haf.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat ZC3H11A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZC3H11A (see all 37):
    hsa-miR-3685 hsa-miR-607 hsa-miR-4328 hsa-miR-15a hsa-miR-503 hsa-miR-374c hsa-miR-424 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidZC3H11A 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: ZC3H11A (NM_014827)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZC3H11A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H11A
    Primer
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    OriGene qPCR primer pairs and template standards for ZC3H11A
    OriGene qSTAR qPCR primer pairs in human, mouse for ZC3H11A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZC3H11A
      QuantiTect SYBR Green Assays in human, mouse, rat ZC3H11A
      QuantiFast Probe-based Assays in human, mouse, rat ZC3H11A

    Additional mRNA sequence: 

    AB014563.1 AK095858.1 AK296983.1 AK310470.1 AL049419.1 BC014268.2 BC038513.2 BC046137.2 
    BC048271.1 CR627439.1 

    Selected DOTS entries (see all 48):

    DT.319879  DT.99941762  DT.121452670  DT.100802807  DT.91757416  DT.95368226  DT.101984844  DT.92024926 
    DT.121452760  DT.95234065  DT.319880  DT.121452703  DT.100689774  DT.100825692  DT.121419632  DT.121419635 
    DT.121452692  DT.95234119  DT.121452745  DT.121452748  DT.95156707  DT.95157215  DT.121452693  DT.121452706 

    Selected AceView cDNA sequences (see all 540):

    BQ420270 AB014563 CA419736 AI570930 AI803216 BQ446621 AA810418 CD243940 
    AI185506 BQ011090 AA569964 CN478993 AA454142 AA535623 AA774128 AA682981 
    CF528479 AA767554 W94384 BU615369 NM_014827 BM661734 CA415029 AA804853 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZC3H11A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATTTTCTAC
    ZC3H11A Expression
    About this image


    ZC3H11A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Thyroid (Endocrine System)
     
     Limb (Muscoskeletal System)
     
     Testis (Reproductive System)
     
     Uterus (Reproductive System)
    ZC3H11A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZC3H11A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.532399
        Custom PCR Arrays for ZC3H11A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H11A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZC3H11A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zc3h11a1 , 5 zinc finger CCCH type containing 11A1, 5 83.06(n)1
    81.27(a)1
      1 (57.94 cM)5
    705791  NM_001276767.11  NP_001263696.11 
     1336198715 
    chicken
    (Gallus gallus)
    Aves ZC3H11A1 zinc finger CCCH-type containing 11A 64.94(n)
    62.66(a)
      421172  NM_001031030.1  NP_001026201.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    51(a)
    50(a)
    many → 1
    many → 1
    4(118062486-118098807)
    GL343281.1(1777450-1779473)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.68112 Xenopus laevis transcribed sequence with moderate similarity more 80.86(n)    BJ618344.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc32e102 wufc32e10 76.22(n)   324551  BC059648.1 


    ENSEMBL Gene Tree for ZC3H11A (if available)
    TreeFam Gene Tree for ZC3H11A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZC3H11A gene
    1 SIMAP similar gene for ZC3H11A using alignment to 5 protein entries:     ZC11A_HUMAN (see all proteins):
    C12orf50

    ZC3H11A for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ZC3H11A
    PGOHUM00000244423 PGOHUM00000243660


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZC3H11A (see all 1277)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903476761,2
    --174928370(+) GTAGAC/GGCAGG 1 -- us2k10--------
    rs65939481,2
    C,F,A--174928373(+) gaggcG/Aggatt 1 -- us2k18Minor allele frequency- A:0.38NA WA CSA 16
    rs125692191,2
    C,F,H--174928501(+) ATTGGC/AAGTTG 1 -- us2k120Minor allele frequency- A:0.29NS EA NA WA 2346
    rs1389227211,2
    --174928707(+) GGTGTC/GGTGGC 1 -- us2k10--------
    rs49512331,2
    C,F,A,H--174928800(+) AAAAAT/GAAATT 1 -- us2k1 trp315Minor allele frequency- G:0.38NA WA CSA EA 518
    rs1490076911,2
    --174928811(+) GGCTAA/CCAGGA 1 -- us2k10--------
    rs49510051,2
    C,F,A,H--174928836(+) TCTGTC/TGACAT 1 -- us2k133Minor allele frequency- T:0.37NA NS EA WA CSA 2926
    rs1932613331,2
    C--174929143(+) CTAATC/TAGAGT 1 -- us2k10--------
    rs1849820611,2
    --174929173(+) AGGGGA/GACCTT 1 -- us2k10--------
    rs1457662671,2
    --174929182(+) TTGGGC/TTCCTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZC3H11A (203764751 - 203823256 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZC3H11A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678729CNV Deletion23128226
    esv2658459CNV Deletion23128226
    esv1633923CNV Insertion17803354
    nsv522989CNV Loss19592680
    nsv520482CNV Loss19592680
    nsv873111CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZC3H11A
    DNA2.0 Custom Variant and Variant Library Synthesis for ZC3H11A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613513    OMIM disorders: --

    3 diseases for ZC3H11A:    
    About MalaCards
    myopia    essential hypertension    hypertension


    ZC3H11A for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZC3H11A
    Human Genome Epidemiology (HuGE) Navigator: ZC3H11A (1 document)

    Export disorders for ZC3H11A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZC3H11A gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with ZC3H11A)
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    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1, 4 Ehret G.B....Chakravarti A. (Eur. J. Hum. Genet. 2009)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    7. The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export. (PubMed id 22928037)2 Folco E.G.... Reed R. (PLoS ONE 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    10. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9877 HGNC: 29093 AceView: KIAA0663 Ensembl:ENSG00000058673 euGenes: HUgn9877
    ECgene: ZC3H11A H-InvDB: ZC3H11A

    (According to HUGE)
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    HUGE: KIAA0663

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZC3H11A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZC3H11A gene:
    Search GeneIP for patents involving ZC3H11A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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