ZC3H10 Gene
protein-coding GIFtS: 47
GCID: GC12P056512
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zinc finger CCCH-type containing 10(Previous name: zinc finger CCCH-type domain containing 10 )
(Previous symbol: ZC3HDC10)
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Aliases
for ZC3H10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger CCCH-Type Containing 101 2 | | ZC3HDC101 2 3 | | Zinc Finger CCCH-Type Domain Containing 101 2 | | FLJ144511 | | Zinc Finger CCCH Domain-Containing Protein 102 |
Export aliases for ZC3H10 gene to outside databasesPrevious GC identifers: GC12P054799 GC12P053553 |
Summaries
for ZC3H10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZC3H10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZC3H10 gene promoter:
RFX1 Nkx2-5 Tal-1beta c-Ets-1 CREB deltaCREB ITF-2 NF-Y CBF(2) ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZC3H10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZC3H10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13.2 Ensembl cytogenetic band: 12q13.2 HGNC cytogenetic band: 12q13.2ZC3H10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P056512: view genomic region
(about GC identifiers)
Start:
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56,511,943 bp from pter |
End:
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56,516,278 bp from pter |
Size:
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4,336 bases |
Orientation:
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plus strand |
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Proteins
for ZC3H10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZC3HA_HUMAN, Q96K80 (See
protein sequence)Recommended Name: Zinc finger CCCH domain-containing protein 10 Size: 434 amino acids; 46052 DaExplore the universe of human proteins at neXtProt for ZC3H10: NX_Q96K80
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96K80
ZC3H10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116175.1
ENSEMBL proteins: ENSP00000257940 ENSP00000450122 ENSP00000448309 ENSP00000448881
Human Recombinant Protein Products:
ZC3H10 Antibody Products:
Assay Products for ZC3H10: |
Protein
Domains /
Families
for ZC3H10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZC3H10 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96K80ProtoNet protein and cluster: Q96K80 1 Blocks protein family: IPB000571 Zn-finger
UniProtKB/Swiss-Prot: ZC3HA_HUMAN, Q96K80Similarity: Contains 3 C3H1-type zinc fingers |
Function
for ZC3H10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZC3H10 (NM_032786) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZC3H10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H10 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZC3H10 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZC3H10:
|
Pathways & Interactions
for ZC3H10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZC3H10
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5 Interacting proteins for ZC3H10 (Q96K801, 2, 3 ENSP000002579404) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ZC3H10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZC3H10
Search CenterWatch for drugs/clinical trials and news about ZC3H10 / ZC3HA
|
Transcripts
for ZC3H10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZC3H10 gene: NM_032786.1 Unigene Cluster for ZC3H10: Zinc finger CCCH-type containing 10 Hs.632706 [show with all ESTs]Unigene Representative Sequence: BC0187085 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000257940(uc001sjp.1) ENST00000552345 ENST00000549973 ENST00000551880
ENST00000546903
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZC3H10 (NM_032786) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZC3H10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H10 |
Additional cDNA sequence: AK027357.1 BC018708.1 9 DOTS entries: DT.110044 DT.121169603 DT.100833901 DT.121169464 DT.91688146 DT.100778958 DT.121169589 DT.95102735 DT.40207823 24/77 AceView cDNA sequences (see all 77): AI969773 BQ448544 AK027357 BQ073665 NM_032786 CR613256 AA190515 AA904967 CA455322 AI864180 BE218067 AI217892 AI095114 BU621020 BU689451 AI758611 BC018708 AU279921 AW272428 BX280083 CB148206 AW172460 AI392828 BQ000497
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZC3H10 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b |
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| SP1: | | | | | - | | - | | | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for ZC3H10
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Expression
for ZC3H10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZC3H10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCACACTGAT
About this image
See ZC3H10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZC3H10
SOURCE GeneReport for Unigene cluster: Hs.632706
SABiosciences Custom PCR Arrays for ZC3H10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZC3H10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZC3H10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZC3H10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZC3H10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H10 |
Orthologs
for ZC3H10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZC3H10 gene from 7/16 species (see all 16) About this table
ENSEMBL Gene Tree for ZC3H10 (if available)
TreeFam Gene Tree for ZC3H10 (if available) |
Paralogs
for ZC3H10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZC3H10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZC3H10 (56511943 - 56516278 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZC3H10: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZC3H10 |
|
Disorders
/ Diseases
for ZC3H10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZC3H10 for disorders About GeneDecksing
1  disease for ZC3H10: About MalaCardsataxia
Human Genome Epidemiology (HuGE) Navigator: ZC3H10 (1 document)
Export disorders for ZC3H10 gene to outside databases
|
Publications
for ZC3H10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZC3H10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZC3H10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)
- Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration. (PubMed id 18814840)1 Guardiola-Serrano F....Altschmied J. (2008)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
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External Searches for ZC3H10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZC3H10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZC3H10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZC3H10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZC3H10 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZC3H10 gene:
Search GeneIP for patents involving ZC3H10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZC3H10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZC3H10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZC3H10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZC3H10 | | | OriGene Protein Over-expression Lysate for ZC3H10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZC3H10 | | OriGene 3'-UTR Clone for ZC3H10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZC3H10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZC3H10 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | Search Tocris compounds for ZC3H10 |
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 | | | ZC3H10 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZC3H10 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZC3H10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZC3H10 |
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