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Aliases for ZC2HC1C Gene

Aliases for ZC2HC1C Gene

  • Zinc Finger, C2HC-Type Containing 1C 2 3
  • Family With Sequence Similarity 164, Member C 2 3
  • C14orf140 3 4
  • FAM164C 3 4
  • Zinc Finger C2HC Domain-Containing Protein 1C 3
  • Chromosome 14 Open Reading Frame 140 2
  • Protein FAM164C 3

External Ids for ZC2HC1C Gene

Previous HGNC Symbols for ZC2HC1C Gene

  • C14orf140
  • FAM164C

Previous GeneCards Identifiers for ZC2HC1C Gene

  • GC14P075530

Summaries for ZC2HC1C Gene

GeneCards Summary for ZC2HC1C Gene

ZC2HC1C (Zinc Finger, C2HC-Type Containing 1C) is a Protein Coding gene. An important paralog of this gene is ZC2HC1B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC2HC1C Gene

Genomics for ZC2HC1C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZC2HC1C Gene

Start:
75,064,170 bp from pter
End:
75,079,987 bp from pter
Size:
15,818 bases
Orientation:
Plus strand

Genomic View for ZC2HC1C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC2HC1C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC2HC1C Gene

No data available for Regulatory Elements for ZC2HC1C Gene

Proteins for ZC2HC1C Gene

  • Protein details for ZC2HC1C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q53FD0-ZC21C_HUMAN
    Recommended name:
    Zinc finger C2HC domain-containing protein 1C
    Protein Accession:
    Q53FD0
    Secondary Accessions:
    • E9PJQ0
    • Q9BTA8
    • Q9H5S9

    Protein attributes for ZC2HC1C Gene

    Size:
    456 amino acids
    Molecular mass:
    51658 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15541.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};

    Alternative splice isoforms for ZC2HC1C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZC2HC1C Gene

Proteomics data for ZC2HC1C Gene at MOPED

Post-translational modifications for ZC2HC1C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZC2HC1C Gene

Domains for ZC2HC1C Gene

Gene Families for ZC2HC1C Gene

HGNC:
  • ZC2HC :Zinc fingers, C2HC-type containing

Protein Domains for ZC2HC1C Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q53FD0

UniProtKB/Swiss-Prot:

ZC21C_HUMAN :
  • Q53FD0
Family:
  • Belongs to the ZC2HC1 family.
Similarity:
  • Contains 1 C2HC-type zinc finger.
genes like me logo Genes that share domains with ZC2HC1C: view

No data available for Suggested Antigen Peptide Sequences for ZC2HC1C Gene

Function for ZC2HC1C Gene

Gene Ontology (GO) - Molecular Function for ZC2HC1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZC2HC1C: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC2HC1C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZC2HC1C Gene

Localization for ZC2HC1C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZC2HC1C Gene

Pathways for ZC2HC1C Gene

SuperPathways for ZC2HC1C Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZC2HC1C Gene

None

No data available for Pathways by source for ZC2HC1C Gene

Transcripts for ZC2HC1C Gene

Unigene Clusters for ZC2HC1C Gene

Zinc finger, C2HC-type containing 1C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC2HC1C

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZC2HC1C Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d ^ 3 ^ 4
SP1: - - -
SP2: - -
SP3:
SP4: - - - - - -
SP5: -

Relevant External Links for ZC2HC1C Gene

GeneLoc Exon Structure for
ZC2HC1C
ECgene alternative splicing isoforms for
ZC2HC1C

Expression for ZC2HC1C Gene

mRNA expression in normal human tissues for ZC2HC1C Gene

mRNA differential expression in normal tissues according to GTEx for ZC2HC1C Gene

This gene is overexpressed in Testis (16.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZC2HC1C Gene

SOURCE GeneReport for Unigene cluster for ZC2HC1C Gene Hs.48642

genes like me logo Genes that share expressions with ZC2HC1C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZC2HC1C Gene

Orthologs for ZC2HC1C Gene

This gene was present in the common ancestor of animals.

Orthologs for ZC2HC1C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZC2HC1C 35
  • 99.27 (n)
  • 98.25 (a)
ZC2HC1C 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM164C 35
  • 81.6 (n)
  • 71.52 (a)
ZC2HC1C 36
  • 61 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZC2HC1C 35
  • 83.7 (n)
  • 75.44 (a)
ZC2HC1C 36
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zc2hc1c 35
  • 75.71 (n)
  • 63.68 (a)
Zc2hc1c 16
Zc2hc1c 36
  • 54 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZC2HC1C 36
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
ManyToMany
rat
(Rattus norvegicus)
Mammalia Zc2hc1c 35
  • 77.28 (n)
  • 64.8 (a)
chicken
(Gallus gallus)
Aves FAM164C 35
  • 51.37 (n)
  • 39.49 (a)
ZC2HC1C 36
  • 27 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZC2HC1C 36
  • 26 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zc2hc1c 35
  • 54.76 (n)
  • 54.29 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC799591 35
  • 51.32 (n)
  • 44.44 (a)
zc2hc1c 36
  • 16 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG42675 36
  • 18 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
OneToOne
Species with no ortholog for ZC2HC1C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZC2HC1C Gene

ENSEMBL:
Gene Tree for ZC2HC1C (if available)
TreeFam:
Gene Tree for ZC2HC1C (if available)

Paralogs for ZC2HC1C Gene

Paralogs for ZC2HC1C Gene

genes like me logo Genes that share paralogs with ZC2HC1C: view

Variants for ZC2HC1C Gene

Sequence variations from dbSNP and Humsavar for ZC2HC1C Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs10246 -- 75,077,767(+) CTGTC(A/T)TCCAC utr-variant-3-prime, nc-transcript-variant, downstream-variant-500B
rs175488 -- 75,080,455(+) TCAGA(C/G)GATGA downstream-variant-500B
rs175489 -- 75,079,547(+) CAAGA(A/G)TAAGC utr-variant-3-prime, nc-transcript-variant
rs175490 -- 75,078,982(+) CGAGA(A/G)TATTA utr-variant-3-prime, nc-transcript-variant
rs175491 -- 75,078,644(+) ATAAT(C/T)CCAGC utr-variant-3-prime, nc-transcript-variant

Relevant External Links for ZC2HC1C Gene

HapMap Linkage Disequilibrium report
ZC2HC1C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZC2HC1C Gene

Disorders for ZC2HC1C Gene

No disorders were found for ZC2HC1C Gene.

No data available for UniProtKB/Swiss-Prot for ZC2HC1C Gene

Publications for ZC2HC1C Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4

Products for ZC2HC1C Gene

Sources for ZC2HC1C Gene

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