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Aliases for ZC2HC1B Gene

Aliases for ZC2HC1B Gene

  • Zinc Finger C2HC-Type Containing 1B 2 3
  • Family With Sequence Similarity 164, Member B 2 3
  • Zinc Finger, C2HC-Type Containing 1B 3 5
  • C6orf94 3 4
  • FAM164B 3 4
  • Chromosome 6 Open Reading Frame 94 2
  • Protein FAM164B 3
  • DJ468K18.5 3

External Ids for ZC2HC1B Gene

Previous HGNC Symbols for ZC2HC1B Gene

  • FAM164B
  • C6orf94

Previous GeneCards Identifiers for ZC2HC1B Gene

  • GC06P144186

Summaries for ZC2HC1B Gene

GeneCards Summary for ZC2HC1B Gene

ZC2HC1B (Zinc Finger C2HC-Type Containing 1B) is a Protein Coding gene. Diseases associated with ZC2HC1B include Diabetes Mellitus, Transient Neonatal, 1. An important paralog of this gene is ZC2HC1A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC2HC1B Gene

Genomics for ZC2HC1B Gene

Regulatory Elements for ZC2HC1B Gene

Enhancers for ZC2HC1B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZC2HC1B on UCSC Golden Path with GeneCards custom track

Genomic Location for ZC2HC1B Gene

143,864,436 bp from pter
143,938,356 bp from pter
73,921 bases
Plus strand

Genomic View for ZC2HC1B Gene

Genes around ZC2HC1B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZC2HC1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZC2HC1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC2HC1B Gene

Proteins for ZC2HC1B Gene

  • Protein details for ZC2HC1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger C2HC domain-containing protein 1B
    Protein Accession:
    Secondary Accessions:
    • B2RUZ7
    • Q5TFG9

    Protein attributes for ZC2HC1B Gene

    222 amino acids
    Molecular mass:
    24665 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI21444.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI21445.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZC2HC1B Gene

Proteomics data for ZC2HC1B Gene at MOPED

Post-translational modifications for ZC2HC1B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZC2HC1B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZC2HC1B Gene

Domains & Families for ZC2HC1B Gene

Gene Families for ZC2HC1B Gene

Protein Domains for ZC2HC1B Gene


Suggested Antigen Peptide Sequences for ZC2HC1B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ZC2HC1 family.
  • Contains 1 C2HC-type zinc finger.
  • Belongs to the ZC2HC1 family.
  • Contains 1 C2HC-type zinc finger.
genes like me logo Genes that share domains with ZC2HC1B: view

Function for ZC2HC1B Gene

Phenotypes for ZC2HC1B Gene

genes like me logo Genes that share phenotypes with ZC2HC1B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZC2HC1B Gene

Localization for ZC2HC1B Gene

Subcellular locations from

Jensen Localization Image for ZC2HC1B Gene COMPARTMENTS Subcellular localization image for ZC2HC1B gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZC2HC1B Gene

Pathways & Interactions for ZC2HC1B Gene

SuperPathways for ZC2HC1B Gene

No Data Available

Interacting Proteins for ZC2HC1B Gene

Gene Ontology (GO) - Biological Process for ZC2HC1B Gene


No data available for Pathways by source and SIGNOR curated interactions for ZC2HC1B Gene

Drugs & Compounds for ZC2HC1B Gene

No Compound Related Data Available

Transcripts for ZC2HC1B Gene

mRNA/cDNA for ZC2HC1B Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZC2HC1B Gene

Zinc finger, C2HC-type containing 1B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZC2HC1B Gene

No ASD Table

Relevant External Links for ZC2HC1B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZC2HC1B Gene

mRNA expression in normal human tissues for ZC2HC1B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZC2HC1B Gene

This gene is overexpressed in Testis (x43.0).

Protein differential expression in normal tissues from HIPED for ZC2HC1B Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZC2HC1B Gene

SOURCE GeneReport for Unigene cluster for ZC2HC1B Gene Hs.121188

genes like me logo Genes that share expression patterns with ZC2HC1B: view

Protein tissue co-expression partners for ZC2HC1B Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for ZC2HC1B Gene

Orthologs for ZC2HC1B Gene

This gene was present in the common ancestor of animals.

Orthologs for ZC2HC1B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZC2HC1B 35
  • 86.76 (n)
  • 84.93 (a)
ZC2HC1B 36
  • 82 (a)
(Canis familiaris)
Mammalia ZC2HC1B 35
  • 87 (n)
  • 84.4 (a)
ZC2HC1B 36
  • 82 (a)
(Mus musculus)
Mammalia Zc2hc1b 35
  • 79.84 (n)
  • 76.74 (a)
Zc2hc1b 16
Zc2hc1b 36
  • 73 (a)
(Pan troglodytes)
Mammalia ZC2HC1B 35
  • 99.1 (n)
  • 98.65 (a)
ZC2HC1B 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zc2hc1b 35
  • 79.84 (n)
  • 77.33 (a)
(Monodelphis domestica)
Mammalia ZC2HC1B 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia ZC2HC1B 36
  • 76 (a)
(Gallus gallus)
Aves C3H6ORF94 35
  • 67.7 (n)
  • 64.2 (a)
ZC2HC1B 36
  • 47 (a)
(Caenorhabditis elegans)
Secernentea T03G11.3 35
  • 52.04 (n)
  • 46.76 (a)
T03G11.3 36
  • 21 (a)
Species with no ortholog for ZC2HC1B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZC2HC1B Gene

Gene Tree for ZC2HC1B (if available)
Gene Tree for ZC2HC1B (if available)

Paralogs for ZC2HC1B Gene

Paralogs for ZC2HC1B Gene

(2) SIMAP similar genes for ZC2HC1B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZC2HC1B: view

Variants for ZC2HC1B Gene

Sequence variations from dbSNP and Humsavar for ZC2HC1B Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs6934118 - 143,864,555(+) CAGAA(A/C/T)CATTT reference, missense
rs1079874 -- 143,928,405(+) ttgtc(A/G)aatat intron-variant
rs1303738 -- 143,932,823(+) gcagc(G/T)gttca intron-variant
rs6570584 -- 143,873,973(+) gtttt(C/T)ctttt intron-variant
rs6570586 -- 143,888,367(+) gtttt(C/T)gctat intron-variant

Variation tolerance for ZC2HC1B Gene

Gene Damage Index Score: 2.58; 44.79% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZC2HC1B Gene

Disorders for ZC2HC1B Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZC2HC1B Gene - From: DISEASES

Disorder Aliases PubMed IDs
diabetes mellitus, transient neonatal, 1
  • diabetes mellitus, transient neonatal
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZC2HC1B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZC2HC1B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZC2HC1B Gene

Publications for ZC2HC1B Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZC2HC1B Gene

Sources for ZC2HC1B Gene