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Aliases for ZC2HC1A Gene

Aliases for ZC2HC1A Gene

  • Zinc Finger, C2HC-Type Containing 1A 2 3
  • Family With Sequence Similarity 164, Member A 2 3
  • C8orf70 3 4
  • FAM164A 3 4
  • Chromosome 8 Open Reading Frame 70 2
  • Protein FAM164A 3
  • CGI-62 3

External Ids for ZC2HC1A Gene

Previous HGNC Symbols for ZC2HC1A Gene

  • C8orf70
  • FAM164A

Previous GeneCards Identifiers for ZC2HC1A Gene

  • GC08P079579

Summaries for ZC2HC1A Gene

GeneCards Summary for ZC2HC1A Gene

ZC2HC1A (Zinc Finger, C2HC-Type Containing 1A) is a Protein Coding gene. An important paralog of this gene is ZC2HC1B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZC2HC1A Gene

Genomics for ZC2HC1A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZC2HC1A Gene

78,666,047 bp from pter
78,719,765 bp from pter
53,719 bases
Plus strand

Genomic View for ZC2HC1A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZC2HC1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZC2HC1A Gene

No data available for Regulatory Elements for ZC2HC1A Gene

Proteins for ZC2HC1A Gene

  • Protein details for ZC2HC1A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger C2HC domain-containing protein 1A
    Protein Accession:
    Secondary Accessions:
    • Q9Y372

    Protein attributes for ZC2HC1A Gene

    325 amino acids
    Molecular mass:
    35092 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZC2HC1A Gene

Proteomics data for ZC2HC1A Gene at MOPED

Post-translational modifications for ZC2HC1A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZC2HC1A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZC2HC1A Gene

Domains & Families for ZC2HC1A Gene

Gene Families for ZC2HC1A Gene

Protein Domains for ZC2HC1A Gene


Suggested Antigen Peptide Sequences for ZC2HC1A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ZC2HC1 family.
  • Contains 1 C2HC-type zinc finger.
  • Belongs to the ZC2HC1 family.
  • Contains 1 C2HC-type zinc finger.
genes like me logo Genes that share domains with ZC2HC1A: view

Function for ZC2HC1A Gene

Gene Ontology (GO) - Molecular Function for ZC2HC1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZC2HC1A: view

Phenotypes for ZC2HC1A Gene

genes like me logo Genes that share phenotypes with ZC2HC1A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC2HC1A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZC2HC1A Gene

Localization for ZC2HC1A Gene

Subcellular locations from

Jensen Localization Image for ZC2HC1A Gene COMPARTMENTS Subcellular localization image for ZC2HC1A gene
Compartment Confidence
cytoskeleton 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZC2HC1A Gene

Pathways & Interactions for ZC2HC1A Gene

SuperPathways for ZC2HC1A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZC2HC1A Gene


No data available for Pathways by source and SIGNOR curated interactions for ZC2HC1A Gene

Drugs & Compounds for ZC2HC1A Gene

No Compound Related Data Available

Transcripts for ZC2HC1A Gene

Unigene Clusters for ZC2HC1A Gene

Zinc finger, C2HC-type containing 1A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZC2HC1A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZC2HC1A Gene

No ASD Table

Relevant External Links for ZC2HC1A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZC2HC1A Gene

mRNA expression in normal human tissues for ZC2HC1A Gene

Protein differential expression in normal tissues from HIPED for ZC2HC1A Gene

This gene is overexpressed in Frontal cortex (23.9) and Fetal Brain (18.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZC2HC1A Gene

SOURCE GeneReport for Unigene cluster for ZC2HC1A Gene Hs.271876

genes like me logo Genes that share expression patterns with ZC2HC1A: view

Protein tissue co-expression partners for ZC2HC1A Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZC2HC1A Gene

Orthologs for ZC2HC1A Gene

This gene was present in the common ancestor of animals.

Orthologs for ZC2HC1A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZC2HC1A 35
  • 89.89 (n)
  • 91.02 (a)
ZC2HC1A 36
  • 91 (a)
(Canis familiaris)
Mammalia ZC2HC1A 35
  • 92.39 (n)
  • 92.9 (a)
ZC2HC1A 36
  • 83 (a)
(Mus musculus)
Mammalia Zc2hc1a 35
  • 84.47 (n)
  • 87.35 (a)
Zc2hc1a 16
Zc2hc1a 36
  • 87 (a)
(Pan troglodytes)
Mammalia ZC2HC1A 35
  • 100 (n)
  • 100 (a)
ZC2HC1A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zc2hc1a 35
  • 85.91 (n)
  • 87.04 (a)
(Monodelphis domestica)
Mammalia ZC2HC1A 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia ZC2HC1A 36
  • 70 (a)
(Gallus gallus)
Aves FAM164A 35
  • 74.3 (n)
  • 75.16 (a)
ZC2HC1A 36
  • 61 (a)
(Anolis carolinensis)
Reptilia ZC2HC1A 36
  • 59 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zc2hc1a 35
  • 67.09 (n)
  • 68.57 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15440 35
(Danio rerio)
Actinopterygii wufc28a05 35
zc2hc1a 35
  • 59.29 (n)
  • 60.9 (a)
zc2hc1a 36
  • 57 (a)
(Caenorhabditis elegans)
Secernentea T03G11.3 36
  • 25 (a)
Species with no ortholog for ZC2HC1A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZC2HC1A Gene

Gene Tree for ZC2HC1A (if available)
Gene Tree for ZC2HC1A (if available)

Paralogs for ZC2HC1A Gene

Paralogs for ZC2HC1A Gene

(1) SIMAP similar genes for ZC2HC1A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZC2HC1A: view

Variants for ZC2HC1A Gene

Sequence variations from dbSNP and Humsavar for ZC2HC1A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1384803 -- 78,669,393(-) CTAGG(C/T)ACTTA intron-variant
rs1483570 -- 78,674,220(+) TGAAT(C/T)CATTT intron-variant
rs2369438 -- 78,669,608(+) AAGAG(A/G)GCTTC intron-variant
rs2369439 -- 78,672,327(+) GTGTG(A/G)GGTCA intron-variant
rs4641056 -- 78,670,261(+) CGCAC(C/T)CGGCG intron-variant

Variation tolerance for ZC2HC1A Gene

Residual Variation Intolerance Score: 20.19% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.86; 34.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZC2HC1A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZC2HC1A Gene

Disorders for ZC2HC1A Gene

Relevant External Links for ZC2HC1A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZC2HC1A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZC2HC1A Gene

Publications for ZC2HC1A Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67
  5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen J.V. … Mann M. (Sci. Signal. 2010) 67

Products for ZC2HC1A Gene

Sources for ZC2HC1A Gene

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