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Aliases for ZBTB8A Gene

Aliases for ZBTB8A Gene

  • Zinc Finger And BTB Domain Containing 8A 2 3
  • BTB/POZ And Zinc-Finger Domains Factor On Chromosome 1 3 4
  • BTB/POZ And Zinc-Finger Domain-Containing Factor 3 4
  • Zinc Finger And BTB Domain Containing 8 2 3
  • BOZF1 3 4
  • Zinc Finger And BTB Domain-Containing Protein 8A 3
  • ZNF916A 3
  • BOZ-F1 4
  • ZBTB8 3

External Ids for ZBTB8A Gene

Previous Symbols for ZBTB8A Gene

  • ZBTB8

Summaries for ZBTB8A Gene

GeneCards Summary for ZBTB8A Gene

ZBTB8A (Zinc Finger And BTB Domain Containing 8A) is a Protein Coding gene. An important paralog of this gene is ENSG00000254553.

UniProtKB/Swiss-Prot for ZBTB8A Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB8A Gene

Genomics for ZBTB8A Gene

Genomic Location for ZBTB8A Gene

32,539,171 bp from pter
32,605,941 bp from pter
66,771 bases
Plus strand

Genomic View for ZBTB8A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB8A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB8A Gene

Regulatory Elements for ZBTB8A Gene

Proteins for ZBTB8A Gene

  • Protein details for ZBTB8A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and BTB domain-containing protein 8A
    Protein Accession:
    Secondary Accessions:
    • Q8IUL5
    • Q8IWR9
    • Q8N2Y5
    • Q96BX0

    Protein attributes for ZBTB8A Gene

    441 amino acids
    Molecular mass:
    50141 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB8A Gene


neXtProt entry for ZBTB8A Gene

Proteomics data for ZBTB8A Gene at MOPED

Post-translational modifications for ZBTB8A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB8A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB8A Gene

Domains for ZBTB8A Gene

Gene Families for ZBTB8A Gene

  • ZNF :Zinc fingers, C2H2-type
  • BTBD :BTB/POZ domain containing

Protein Domains for ZBTB8A Gene


  • Contains 1 BTB (POZ) domain.:
    • Q96BR9
  • Contains 2 C2H2-type zinc fingers.:
    • Q96BR9
genes like me logo Genes that share domains with ZBTB8A: view

Function for ZBTB8A Gene

Molecular function for ZBTB8A Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB8A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB8A: view

Phenotypes for ZBTB8A Gene

genes like me logo Genes that share phenotypes with ZBTB8A: view

miRNA for ZBTB8A Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB8A Gene

Localization for ZBTB8A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB8A Gene

Subcellular locations from

Jensen Localization Image for ZBTB8A Gene COMPARTMENTS Subcellular localization image for ZBTB8A gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZBTB8A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB8A: view

Pathways for ZBTB8A Gene

SuperPathways for ZBTB8A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB8A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZBTB8A: view

No data available for Pathways by source for ZBTB8A Gene

Transcripts for ZBTB8A Gene

mRNA/cDNA for ZBTB8A Gene

(3) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBTB8A Gene

Zinc finger and BTB domain containing 8A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB8A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8
SP1: -
SP2: -
SP3: - -

Relevant External Links for ZBTB8A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZBTB8A Gene

mRNA expression in normal human tissues for ZBTB8A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZBTB8A Gene

SOURCE GeneReport for Unigene cluster for ZBTB8A Gene Hs.546479

genes like me logo Genes that share expressions with ZBTB8A: view

Orthologs for ZBTB8A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB8A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZBTB8A 36
  • 99.55 (n)
  • 99.32 (a)
  • 99 (a)
(Bos Taurus)
Mammalia ZBTB8A 36
  • 91.08 (n)
  • 94.78 (a)
  • 87 (a)
(Canis familiaris)
Mammalia ZBTB8A 36
  • 91.21 (n)
  • 94.77 (a)
  • 95 (a)
(Mus musculus)
Mammalia Zbtb8a 36
  • 80.41 (n)
  • 82.95 (a)
Zbtb8a 16
Zbtb8a 37
  • 85 (a)
(Monodelphis domestica)
Mammalia ZBTB8A 37
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia ZBTB8A 37
  • 81 (a)
(Rattus norvegicus)
Mammalia Zbtb8a 36
  • 81.24 (n)
  • 85.17 (a)
(Gallus gallus)
Aves ZBTB8A 36
  • 74.79 (n)
  • 79.5 (a)
  • 73 (a)
(Anolis carolinensis)
Reptilia ZBTB8A 37
  • 72 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zbtb8a.1 36
  • 60.43 (n)
  • 57.31 (a)
(Danio rerio)
Actinopterygii ZBTB8A 37
  • 44 (a)
zgc:136874 36
  • 52.44 (n)
  • 51.77 (a)
Species with no ortholog for ZBTB8A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB8A Gene

Gene Tree for ZBTB8A (if available)
Gene Tree for ZBTB8A (if available)

Paralogs for ZBTB8A Gene

Selected SIMAP similar genes for ZBTB8A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZBTB8A: view

Variants for ZBTB8A Gene

Sequence variations from dbSNP and Humsavar for ZBTB8A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs367853 -- 32,606,350(-) gttcc(C/T)ggcat downstream-variant-500B
rs420993 -- 32,605,145(+) actcc(A/C)tcaaa utr-variant-3-prime, nc-transcript-variant
rs422215 -- 32,603,153(-) AGTCC(A/G)TCTCA utr-variant-3-prime, nc-transcript-variant
rs428100 -- 32,598,427(+) agatg(C/G)agttt intron-variant
rs432974 -- 32,604,922(-) ccgcc(C/T)gcctc utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ZBTB8A Gene

Variant ID Type Subtype PubMed ID
esv2666068 CNV Deletion 23128226
nsv461039 CNV Loss 19166990
esv2746508 CNV Deletion 23290073
esv2576617 CNV Insertion 19546169
nsv512732 CNV Insertion 21212237
esv1277305 CNV Insertion 17803354
esv2671633 CNV Deletion 23128226

Relevant External Links for ZBTB8A Gene

HapMap Linkage Disequilibrium report

Disorders for ZBTB8A Gene

Relevant External Links for ZBTB8A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZBTB8A: view

No data available for UniProtKB/Swiss-Prot for ZBTB8A Gene

Publications for ZBTB8A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Regulation of the cyclin-dependent kinase inhibitor 1A gene (CDKN1A) by the repressor BOZF1 through inhibition of p53 acetylation and transcription factor Sp1 binding. (PMID: 23329847) Kim M.K. … Hur M.W. (J. Biol. Chem. 2013) 2 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3

Products for ZBTB8A Gene

Sources for ZBTB8A Gene

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