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Aliases for ZBTB6 Gene

Aliases for ZBTB6 Gene

  • Zinc Finger And BTB Domain Containing 6 2 3
  • Zinc Finger Protein 482 2 3 4
  • Zinc Finger Protein With Interaction Domain 3 4
  • ZNF482 3 4
  • ZID 3 4
  • Zinc Finger And BTB Domain-Containing Protein 6 3

External Ids for ZBTB6 Gene

Previous HGNC Symbols for ZBTB6 Gene

  • ZNF482

Previous GeneCards Identifiers for ZBTB6 Gene

  • GC09M124710
  • GC09M125670
  • GC09M095286

Summaries for ZBTB6 Gene

GeneCards Summary for ZBTB6 Gene

ZBTB6 (Zinc Finger And BTB Domain Containing 6) is a Protein Coding gene. An important paralog of this gene is NACC2.

UniProtKB/Swiss-Prot for ZBTB6 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB6 Gene

Genomics for ZBTB6 Gene

Regulatory Elements for ZBTB6 Gene

Genomic Location for ZBTB6 Gene

Start:
122,908,056 bp from pter
End:
122,913,330 bp from pter
Size:
5,275 bases
Orientation:
Minus strand

Genomic View for ZBTB6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB6 Gene

Proteins for ZBTB6 Gene

  • Protein details for ZBTB6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15916-ZBTB6_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 6
    Protein Accession:
    Q15916
    Secondary Accessions:
    • A8K8N6

    Protein attributes for ZBTB6 Gene

    Size:
    424 amino acids
    Molecular mass:
    48236 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZBTB6 Gene

Proteomics data for ZBTB6 Gene at MOPED

Post-translational modifications for ZBTB6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB6 Gene

Domains for ZBTB6 Gene

Gene Families for ZBTB6 Gene

HGNC:
  • BTBD :BTB/POZ domain containing
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZBTB6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q15916

UniProtKB/Swiss-Prot:

ZBTB6_HUMAN :
  • Q15916
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB6: view

Function for ZBTB6 Gene

Molecular function for ZBTB6 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB6: view

Animal Model Products

CRISPR Products

miRNA for ZBTB6 Gene

Transcription Factor Targeting for ZBTB6 Gene

Selected GeneGlobe predicted Target genes for ZBTB6

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB6

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models and HOMER Transcription for ZBTB6 Gene

Localization for ZBTB6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB6 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB6 Gene COMPARTMENTS Subcellular localization image for ZBTB6 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZBTB6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB6: view

Pathways for ZBTB6 Gene

SuperPathways for ZBTB6 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB6: view

No data available for Pathways by source for ZBTB6 Gene

Transcripts for ZBTB6 Gene

mRNA/cDNA for ZBTB6 Gene

(4) Additional mRNA sequences :
(43) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBTB6 Gene

Zinc finger and BTB domain containing 6:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB6

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZBTB6

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB6 Gene

No ASD Table

Relevant External Links for ZBTB6 Gene

GeneLoc Exon Structure for
ZBTB6
ECgene alternative splicing isoforms for
ZBTB6

Expression for ZBTB6 Gene

mRNA expression in normal human tissues for ZBTB6 Gene

SOURCE GeneReport for Unigene cluster for ZBTB6 Gene Hs.654596

mRNA Expression by UniProt/SwissProt for ZBTB6 Gene

Q15916-ZBTB6_HUMAN
Tissue specificity: Widely expressed with highest levels in brain.
genes like me logo Genes that share expressions with ZBTB6: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for ZBTB6 Gene

Orthologs for ZBTB6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB6 35
  • 99.92 (n)
  • 100 (a)
ZBTB6 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB6 35
  • 92.37 (n)
  • 94.58 (a)
ZBTB6 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB6 35
  • 91.73 (n)
  • 96.22 (a)
ZBTB6 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb6 35
  • 89.91 (n)
  • 92.67 (a)
Zbtb6 16
Zbtb6 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB6 36
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb6 35
  • 89.13 (n)
  • 90.31 (a)
chicken
(Gallus gallus)
Aves ZBTB6 35
  • 72.82 (n)
  • 76.7 (a)
ZBTB6 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 33 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.19003 35
zbtb6 35
  • 68.61 (n)
  • 72.84 (a)
Species with no ortholog for ZBTB6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBTB6 Gene

ENSEMBL:
Gene Tree for ZBTB6 (if available)
TreeFam:
Gene Tree for ZBTB6 (if available)

Paralogs for ZBTB6 Gene

Selected SIMAP similar genes for ZBTB6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZBTB6: view

Variants for ZBTB6 Gene

Sequence variations from dbSNP and Humsavar for ZBTB6 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1147321 -- 122,910,772(-) TATAA(A/C/G/T)GTTTG utr-variant-3-prime
rs1147322 -- 122,913,322(-) TTTTC(C/T)TCCAG utr-variant-5-prime
rs2239539 -- 122,913,280(-) TGCCG(C/T)GGAAT utr-variant-5-prime
rs2239540 -- 122,912,716(-) GGTCT(C/T)GTATT intron-variant
rs2596694 -- 122,914,993(+) ccgcg(C/T)ccggc upstream-variant-2KB

Relevant External Links for ZBTB6 Gene

HapMap Linkage Disequilibrium report
ZBTB6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZBTB6 Gene

Disorders for ZBTB6 Gene

No disorders were found for ZBTB6 Gene.

No data available for UniProtKB/Swiss-Prot for ZBTB6 Gene

Publications for ZBTB6 Gene

  1. The POZ domain: a conserved protein-protein interaction motif. (PMID: 7958847) Bardwell V.J. … Treisman R. (Genes Dev. 1994) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. NAC1, a POZ/BTB protein that functions as a corepressor. (PMID: 19121354) Korutla L. … Mackler S.A. (Neurochem. Int. 2009) 3
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3
  5. Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling. (PMID: 25391492) Lamoliatte F. … Thibault P. (Nat Commun 2014) 3

Products for ZBTB6 Gene

Sources for ZBTB6 Gene

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