ZBTB47 Gene
protein-coding GIFtS: 44
GCID: GC03P042674
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zinc finger and BTB domain containing 47(Previous name: zinc finger protein 651 )
(Previous symbol: ZNF651)
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Aliases
for ZBTB47 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And BTB Domain Containing 471 2 | | Zinc Finger Protein 6511 2 3 | | ZNF6511 2 3 | | KIAA11901 3 | | DKFZp434N06151 | | Zinc Finger And BTB Domain-Containing Protein 472 |
Export aliases for ZBTB47 gene to outside databases |
Summaries
for ZBTB47 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZBT47_HUMAN, Q9UFB7Function: May be involved in transcriptional regulation
|
Genomic Views
for ZBTB47 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZBTB47 gene promoter:
STAT1 STAT4 STAT1beta STAT6 STAT5A STAT1alpha c-Ets-1 HOXA5 STAT2 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBTB47
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB47 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p22.1 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p22.1ZBTB47 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P042674: view genomic region
(about GC identifiers)
Start:
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42,695,176 bp from pter |
End:
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42,709,072 bp from pter |
Size:
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13,897 bases |
Orientation:
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plus strand |
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Proteins
for ZBTB47 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZBT47_HUMAN, Q9UFB7 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 47 Size: 371 amino acids; 42465 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q8WTY8 Q9ULN0Explore the universe of human proteins at neXtProt for ZBTB47: NX_Q9UFB7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UFB7
ZBTB47 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_660149.2
ENSEMBL proteins: ENSP00000232974 ENSP00000420968 ENSP00000411491
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZBTB47 for ontologies About GeneDecksing
ZBTB47 Antibody Products:
Assay Products for ZBTB47: |
Protein
Domains /
Families
for ZBTB47 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBTB47 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UFB7ProtoNet protein and cluster: Q9UFB7 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZBT47_HUMAN, Q9UFB7Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 9 C2H2-type zinc fingers |
Function
for ZBTB47 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZBT47_HUMAN, Q9UFB7Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZBTB47 (NM_145166) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB47 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB47 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB47 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZBTB47 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZBTB47 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBTB47
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZBTB47 (Q9UFB72, 3 ENSP000004114914) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZBTB47 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZBTB47 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZBTB47
Search CenterWatch for drugs/clinical trials and news about ZBTB47 / ZBT47
|
Transcripts
for ZBTB47 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZBTB47 gene: NM_145166.3 Unigene Cluster for ZBTB47: Zinc finger and BTB domain containing 47 Hs.409561 [show with all ESTs]Unigene Representative Sequence: NM_1451663 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000232974 ENST00000505904 ENST00000457842(uc003clu.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZBTB47 (NM_145166) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB47 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB47 |
Additional cDNA sequence: AB033016.1 AK127065.1 AL133062.1 BC021855.1 6 DOTS entries: DT.86996907 DT.215143 DT.100009678 DT.91741348 DT.100741924 DT.91873311 24/96 AceView cDNA sequences (see all 96): BM674023 BU743025 BM700666 AI380709 BM984714 BP343496 Z41509 AI471220 BM830427 BC021855 W95172 BM785547 AB033016 AI937491 BX099471 BF530692 BU620464 BM718586 BM856386 NM_145166 AI246244 F24608 F05045 AL133062
GeneLoc Exon Structure
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Expression
for ZBTB47 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZBTB47 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGAGTGAGAG
About this image
See ZBTB47 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBTB47
SOURCE GeneReport for Unigene cluster: Hs.409561
SABiosciences Custom PCR Arrays for ZBTB47
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB47
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZBTB47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB47 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB47 |
Orthologs
for ZBTB47 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZBTB47 gene from 6/13 species (see all 13) About this table
ENSEMBL Gene Tree for ZBTB47 (if available)
TreeFam Gene Tree for ZBTB47 (if available) |
Paralogs
for ZBTB47 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZBTB47 gene
- ZNF6522
18/448 SIMAP similar genes for ZBTB47 using alignment to 3 protein entries: ZBT47_HUMAN (see all proteins)
(see all similar genes):ZNF148 DKFZp434J0650 ZBTB21 ZNF652 ZNF775 kr-znf3
ZNF72 ZNF78L1 ZFS-2 KLHL32 MYNN ZFS-4
ZNF214 A-328A3.4 HZF16 ZFP41 ZNF ZNF227
ZBTB47 for paralogs About GeneDecksing
|
Genomic Variants
for ZBTB47 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZBTB47 (42695176 - 42709072 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZBTB47: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBTB47 |
|
Disorders
/ Diseases
for ZBTB47 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZBTB47 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZBTB47 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZBTB47) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- CBFA2T3-ZNF651, like CBFA2T3-ZNF652, functions as a t ranscriptional corepressor complex. (PubMed id 20116376)1 Kumar R....Callen D.F. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZBTB47 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZBTB47 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZBTB47 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZBTB47 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZBTB47 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZBTB47 gene:
Search GeneIP for patents involving ZBTB47
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZBTB47 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZBTB47 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZBTB47 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB47 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZBTB47 | | OriGene 3'-UTR Clone for ZBTB47 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB47 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 |  |  |  | |
| | | | Search Tocris compounds for ZBTB47 |
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 | | | ZBTB47 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB47 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZBTB47 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB47 |
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