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Aliases for ZBTB47 Gene

Aliases for ZBTB47 Gene

  • Zinc Finger And BTB Domain Containing 47 2 3 5
  • Zinc Finger Protein 651 2 3 4
  • ZNF651 3 4
  • Zinc Finger And BTB Domain-Containing Protein 47 3
  • KIAA1190 4

External Ids for ZBTB47 Gene

Previous HGNC Symbols for ZBTB47 Gene

  • ZNF651

Previous GeneCards Identifiers for ZBTB47 Gene

  • GC03P042674

Summaries for ZBTB47 Gene

GeneCards Summary for ZBTB47 Gene

ZBTB47 (Zinc Finger And BTB Domain Containing 47) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF652.

UniProtKB/Swiss-Prot for ZBTB47 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB47 Gene

Genomics for ZBTB47 Gene

Regulatory Elements for ZBTB47 Gene

Enhancers for ZBTB47 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F042631 0.2 ENCODE 12.6 -21.8 -21801 0.2 LOC101928323 ZBTB47 SEC22C SS18L2 CCDC13-AS1 CCDC13
GH03F042650 1.3 FANTOM5 ENCODE 0.8 +0.1 145 6.4 HDGF PKNOX1 ZFP64 SIN3A DMAP1 ZNF121 GLIS2 KLF7 FOS SP3 SEC22C NKTR SS18L2 HHATL FAM198A LOC101928323 ZBTB47
GH03F042610 1.3 Ensembl ENCODE 0.2 -41.6 -41567 2.7 HDGF ATF1 ZFP64 ARID4B SIN3A DMAP1 GLIS2 ZNF143 KLF7 FOS NKTR SEC22C SS18L2 ZBTB47
GH03F042599 1.1 ENCODE 0.2 -52.6 -52550 3.8 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 SEC22C NKTR ZBTB47
GH03F042637 0.7 ENCODE 0.3 -15.0 -15045 2.6 PKNOX1 JUNB CEBPG GABPA SCRT2 EED THRAP3 TCF7 ETV6 CREM SEC22C ZBTB47
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZBTB47 on UCSC Golden Path with GeneCards custom track

Promoters for ZBTB47 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001847189 816 1801 ZFP64 SIN3A DMAP1 GLIS2 KLF7 SP3 PPARG KAT8 SMARCA4 GLIS1

Genomic Location for ZBTB47 Gene

Chromosome:
3
Start:
42,653,684 bp from pter
End:
42,667,580 bp from pter
Size:
13,897 bases
Orientation:
Plus strand

Genomic View for ZBTB47 Gene

Genes around ZBTB47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBTB47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBTB47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB47 Gene

Proteins for ZBTB47 Gene

  • Protein details for ZBTB47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UFB7-ZBT47_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 47
    Protein Accession:
    Q9UFB7
    Secondary Accessions:
    • H7BXD3
    • Q6ZSY6
    • Q8WTY8
    • Q9ULN0

    Protein attributes for ZBTB47 Gene

    Size:
    747 amino acids
    Molecular mass:
    82760 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH21855.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAB61386.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZBTB47 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB47 Gene

Post-translational modifications for ZBTB47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB47 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB47 Gene

Domains & Families for ZBTB47 Gene

Gene Families for ZBTB47 Gene

Suggested Antigen Peptide Sequences for ZBTB47 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UFB7

UniProtKB/Swiss-Prot:

ZBT47_HUMAN :
  • Contains 1 BTB (POZ) domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 BTB (POZ) domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB47: view

Function for ZBTB47 Gene

Molecular function for ZBTB47 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZBTB47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB47: view

Phenotypes for ZBTB47 Gene

GenomeRNAi human phenotypes for ZBTB47:
genes like me logo Genes that share phenotypes with ZBTB47: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBTB47 Gene

Localization for ZBTB47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB47 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZBTB47 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZBTB47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB47: view

Pathways & Interactions for ZBTB47 Gene

SuperPathways for ZBTB47 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB47: view

No data available for Pathways by source and SIGNOR curated interactions for ZBTB47 Gene

Transcripts for ZBTB47 Gene

mRNA/cDNA for ZBTB47 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(96) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBTB47 Gene

Zinc finger and BTB domain containing 47:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB47 Gene

No ASD Table

Relevant External Links for ZBTB47 Gene

GeneLoc Exon Structure for
ZBTB47
ECgene alternative splicing isoforms for
ZBTB47

Expression for ZBTB47 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZBTB47 Gene

Protein differential expression in normal tissues from HIPED for ZBTB47 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZBTB47 Gene



Protein tissue co-expression partners for ZBTB47 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZBTB47 Gene:

ZBTB47

SOURCE GeneReport for Unigene cluster for ZBTB47 Gene:

Hs.409561
genes like me logo Genes that share expression patterns with ZBTB47: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB47 Gene

Orthologs for ZBTB47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB47 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB47 35
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB47 35
  • 89 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB47 34 35
  • 88.31 (n)
dog
(Canis familiaris)
Mammalia ZBTB47 34 35
  • 87.95 (n)
mouse
(Mus musculus)
Mammalia Zfp651 35
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB47 35
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZBTB47 35
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZBTB47 35
  • 64 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13314 34
zebrafish
(Danio rerio)
Actinopterygii zbtb47b 35
  • 94 (a)
OneToMany
zbtb47a 35
  • 54 (a)
OneToMany
Species where no ortholog for ZBTB47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB47 Gene

ENSEMBL:
Gene Tree for ZBTB47 (if available)
TreeFam:
Gene Tree for ZBTB47 (if available)

Paralogs for ZBTB47 Gene

Paralogs for ZBTB47 Gene

(435) SIMAP similar genes for ZBTB47 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZBTB47: view

Variants for ZBTB47 Gene

Sequence variations from dbSNP and Humsavar for ZBTB47 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs11129967 -- 42,665,789(+) GAGGC(A/G)CAGCC utr-variant-3-prime
rs111314446 -- 42,667,865(+) GTGCT(C/G)CCACT downstream-variant-500B
rs112002106 -- 42,654,464(+) GGCGC(C/G)CCGCG intron-variant, upstream-variant-2KB
rs112880995 -- 42,663,726(+) ACAGG(A/G)GAGCT intron-variant
rs113130584 -- 42,654,369(+) CACAC(A/C)ACGCG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ZBTB47 Gene

Variant ID Type Subtype PubMed ID
nsv3781 CNV insertion 18451855
nsv954471 CNV deletion 24416366

Variation tolerance for ZBTB47 Gene

Gene Damage Index Score: 3.66; 56.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBTB47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZBTB47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB47 Gene

Disorders for ZBTB47 Gene

Relevant External Links for ZBTB47

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZBTB47

No disorders were found for ZBTB47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBTB47 Gene

Publications for ZBTB47 Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G. … Cagney G. (Sci. Rep. 2015) 3 64
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3 64
  5. CBFA2T3-ZNF651, like CBFA2T3-ZNF652, functions as a transcriptional corepressor complex. (PMID: 20116376) Kumar R. … Callen D.F. (FEBS Lett. 2010) 3 64

Products for ZBTB47 Gene

Sources for ZBTB47 Gene

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