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Aliases for ZBTB45 Gene

Aliases for ZBTB45 Gene

  • Zinc Finger And BTB Domain Containing 45 2 3
  • Zinc Finger Protein 499 2 3 4
  • ZNF499 3 4
  • Zinc Finger And BTB Domain-Containing Protein 45 3

External Ids for ZBTB45 Gene

Previous HGNC Symbols for ZBTB45 Gene

  • ZNF499

Previous GeneCards Identifiers for ZBTB45 Gene

  • GC19M063717
  • GC19M059024
  • GC19M055335

Summaries for ZBTB45 Gene

GeneCards Summary for ZBTB45 Gene

ZBTB45 (Zinc Finger And BTB Domain Containing 45) is a Protein Coding gene. An important paralog of this gene is NACC2.

UniProtKB/Swiss-Prot for ZBTB45 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB45 Gene

Genomics for ZBTB45 Gene

Regulatory Elements for ZBTB45 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZBTB45 Gene

Start:
58,513,530 bp from pter
End:
58,538,911 bp from pter
Size:
25,382 bases
Orientation:
Minus strand

Genomic View for ZBTB45 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB45 Gene

Proteins for ZBTB45 Gene

  • Protein details for ZBTB45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96K62-ZBT45_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 45
    Protein Accession:
    Q96K62
    Secondary Accessions:

    Protein attributes for ZBTB45 Gene

    Size:
    511 amino acids
    Molecular mass:
    54008 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZBTB45 Gene

Proteomics data for ZBTB45 Gene at MOPED

Post-translational modifications for ZBTB45 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB45 Gene

No data available for DME Specific Peptides for ZBTB45 Gene

Domains for ZBTB45 Gene

Gene Families for ZBTB45 Gene

HGNC:
  • BTBD :BTB/POZ domain containing
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZBTB45 Gene

Suggested Antigen Peptide Sequences for ZBTB45 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96K62

UniProtKB/Swiss-Prot:

ZBT45_HUMAN :
  • Q96K62
Domain:
  • Contains 1 BTB (POZ) domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB45: view

Function for ZBTB45 Gene

Molecular function for ZBTB45 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB45: view

Phenotypes for ZBTB45 Gene

GenomeRNAi human phenotypes for ZBTB45:
genes like me logo Genes that share phenotypes with ZBTB45: view

Animal Model Products

CRISPR Products

miRNA for ZBTB45 Gene

miRTarBase miRNAs that target ZBTB45

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB45

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB45 Gene

Localization for ZBTB45 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB45 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB45 Gene COMPARTMENTS Subcellular localization image for ZBTB45 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZBTB45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB45: view

Pathways for ZBTB45 Gene

SuperPathways for ZBTB45 Gene

No Data Available

Interacting Proteins for ZBTB45 Gene

Gene Ontology (GO) - Biological Process for ZBTB45 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB45: view

No data available for Pathways by source for ZBTB45 Gene

Transcripts for ZBTB45 Gene

Unigene Clusters for ZBTB45 Gene

Zinc finger and BTB domain containing 45:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB45

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB45 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4
SP1: - - -
SP2: -
SP3: - -
SP4:

Relevant External Links for ZBTB45 Gene

GeneLoc Exon Structure for
ZBTB45
ECgene alternative splicing isoforms for
ZBTB45

Expression for ZBTB45 Gene

mRNA expression in normal human tissues for ZBTB45 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZBTB45 Gene

SOURCE GeneReport for Unigene cluster for ZBTB45 Gene Hs.515662

genes like me logo Genes that share expressions with ZBTB45: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB45 Gene

Orthologs for ZBTB45 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB45 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB45 35
  • 99.59 (n)
  • 99.59 (a)
ZBTB45 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB45 35
  • 81.72 (n)
  • 84.14 (a)
dog
(Canis familiaris)
Mammalia ZBTB45 35
  • 81.96 (n)
  • 88.24 (a)
ZBTB45 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb45 35
  • 80.5 (n)
  • 86.69 (a)
Zbtb45 16
Zbtb45 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb45 35
  • 79.91 (n)
  • 86.5 (a)
lizard
(Anolis carolinensis)
Reptilia ZBTB45 36
  • 39 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.19474 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485837 35
  • 57.45 (n)
  • 57.6 (a)
Str.14835 35
Species with no ortholog for ZBTB45:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZBTB45 Gene

ENSEMBL:
Gene Tree for ZBTB45 (if available)
TreeFam:
Gene Tree for ZBTB45 (if available)

Paralogs for ZBTB45 Gene

Pseudogenes.org Pseudogenes for ZBTB45 Gene

genes like me logo Genes that share paralogs with ZBTB45: view

Variants for ZBTB45 Gene

Sequence variations from dbSNP and Humsavar for ZBTB45 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4801276 -- 58,520,106(+) CAAGT(C/G)CCCAA upstream-variant-2KB, utr-variant-5-prime
rs4801602 -- 58,514,318(+) GCGGA(A/C)GACAG intron-variant
rs7248520 -- 58,521,894(+) CTAGA(A/T)CAAAG upstream-variant-2KB
rs7260485 -- 58,521,385(+) aaaaa(A/G)aaaga upstream-variant-2KB
rs11545185 -- 58,517,218(-) CACCG(C/T)CTGCG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZBTB45 Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV Gain+Loss 19592680
nsv828657 CNV Gain 20364138
nsv912546 CNV Loss 21882294

Relevant External Links for ZBTB45 Gene

HapMap Linkage Disequilibrium report
ZBTB45
Human Gene Mutation Database (HGMD)
ZBTB45

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB45 Gene

Disorders for ZBTB45 Gene

No disorders were found for ZBTB45 Gene.

No data available for UniProtKB/Swiss-Prot for ZBTB45 Gene

Publications for ZBTB45 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZBTB45 Gene

Sources for ZBTB45 Gene

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