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Aliases & Descriptions for ZBTB44
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| BTBD15 2, 3 | | HSPC063 1, 2 | | MGC26123 2 | | MGC57431 2 | | MGC60348 2 | | MGC88058 2 | | ZNF851 1, 2 |
| | | Descriptions |
|---|
| BTB (POZ) domain containing 15 1, 2 | | BTB/POZ domain-containing protein 15 3 | | zinc finger and BTB domain containing 44 2 |
|
| | Search outside databases for aliases for ZBTB44 gene |
Summaries for ZBTB44(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZBT44_HUMAN, Q8NCP5Function: May be involved in transcriptional regulation (By similarity) |
Genomic Location for ZBTB44
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q24.3 Ensembl cytogenetic band: 11q24.3 HGNC cytogenetic band: 11q24.3ZBTB44 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M129603:
(about GC identifiers)
Start:
|
129,597,423 bp from pter |
End:
|
129,689,817 bp from pter |
Size:
|
92,395 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000011.8 NT_033899.7
| Proteins for ZBTB44
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: ZBT44_HUMAN, Q8NCP5 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 44 Size: 570 amino acids; 63848 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q6IPT8 Q86VJ7 Q86XX5Alternative splicing: 4 isoforms: Q8NCP5-1 Q8NCP5-2 Q8NCP5-3 Q8NCP5-4 Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_054874.3
ENSEMBL proteins: ENSP00000350574 ENSP00000341618 ENSP00000380861
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: ZBTB44 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for ZBTB44: Assays for ZBTB44: | Protein
Domains/ Families for ZBTB44(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q8NCP5
ProtoNet protein and cluster: Q8NCP5 1 Blocks protein family: IPB000210 BTB/POZ domain
UniProtKB/Swiss-Prot: ZBT44_HUMAN, Q8NCP5Similarity: Contains 1 BTB (POZ) domainSimilarity: Contains 4 C2H2-type zinc fingers | Gene Function for ZBTB44
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014155
Applied Biosystems Silencer® siRNAs for ZBTB44
Sigma-Aldrich siRNA and siRNA Panels for ZBTB44  Sigma-Aldrich shRNA for ZBTB44  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014155                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014155                                  untagged cDNA clones in CMV expression vector (see all 2): NM_014155 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_014155
UniProtKB/Swiss-Prot: ZBT44_HUMAN, Q8NCP5Function: May be involved in transcriptional regulation (By similarity)4 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for ZBTB44
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| --2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006350 | transcription |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | About this table
|
Drugs & Compounds for ZBTB44(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for ZBTB44
|
Transcripts for ZBTB44(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014155
Sigma-Aldrich siRNA and siRNA Panels for ZBTB44  Sigma-Aldrich shRNA for ZBTB44  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_014155 REFSEQ mRNAs for ZBTB44 gene: NM_014155.4
Applied Biosystems TaqMan ® Gene Expression Assays: NM_014155               OriGene GFP tagged cDNA clone in CMV expression vector: NM_014155                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014155                                  untagged cDNA clones in CMV expression vector (see all 2): NM_014155  Additional cDNA sequence: AF161548.1 AK023933.1 AK024659.1 AK026770.1 AK096676.1 AK130071.1 AK314701.1 BC017675.2 BC040658.1 BC071729.1 CR615509.1 13 DOTS entries: DT.453369 DT.100646532 DT.95328396 DT.100748982 DT.115092 DT.92070124 DT.40127822 DT.91699219 DT.95270526 DT.120736652 DT.120779902 DT.102844137 DT.40131694 24/270 AceView cDNA sequences (see all 270
):BM969910 AA480979 CD642602 AA931090 AU141844 BQ953305 T16371 BG565590 BQ130575 CA391236 AA765505 AI807684 AK024659 CK821904 BC017675 AA480980 AA352857 BM718607 AI245892 AA723924 AI989464 AI866261 AK023933 AA286906
highest scoring ESTs for ZBTB44:AA521091 AI927695 AF150253 AF161548 AL707880 BC071729 BG723160 BI459825 BI460291 BI520347 Unigene Cluster for ZBTB44: Zinc finger and BTB domain containing 44 Hs.719099 [show with all ESTs]Unigene Representative Sequence: NM_014155
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB44 (see all 9
)
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for ZBTB44
3 Ensembl transcripts including schematic representations: ENST00000357899
ENST00000338191
ENST00000397753
|
Expression for ZBTB44
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ZBTB44 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB44
1 / 2 / 3 11 probe-sets matching ZBTB44 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.719099
|
Orthologs for ZBTB44
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZBTB44 gene from 5/9 species (see all 9
)
About this table Species with no ortholog for ZBTB44
ENSEMBL Gene Tree for ZBTB44 | Paralogs for ZBTB44(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for ZBTB44 gene
- ZBTB242 ZBTB7C2 ZBTB7A2 ZBTB7B2
|
SNPs/Variants for ZBTB44(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ZBTB44 (up to first 250kb)
|
Disorders & Mutations for ZBTB44
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for ZBTB44(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for ZBTB44 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 9 PubMed articles for ZBTB44 gene: |
Search for ZBTB44
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZBTB44
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ZBTB44
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBTB44(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for ZBTB44(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for ZBTB44:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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