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Aliases for ZBTB44 Gene

Aliases for ZBTB44 Gene

  • Zinc Finger And BTB Domain Containing 44 2 3 5
  • BTB/POZ Domain-Containing Protein 15 3 4
  • BTB (POZ) Domain Containing 15 2 3
  • Zinc Finger Protein 851 3 4
  • BTBD15 3 4
  • ZNF851 3 4
  • HSPC063 3

External Ids for ZBTB44 Gene

Previous HGNC Symbols for ZBTB44 Gene

  • BTBD15

Previous GeneCards Identifiers for ZBTB44 Gene

  • GC11M129603
  • GC11M130096
  • GC11M126049

Summaries for ZBTB44 Gene

GeneCards Summary for ZBTB44 Gene

ZBTB44 (Zinc Finger And BTB Domain Containing 44) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is NFE2.

UniProtKB/Swiss-Prot for ZBTB44 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB44 Gene

Genomics for ZBTB44 Gene

Regulatory Elements for ZBTB44 Gene

Enhancers for ZBTB44 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZBTB44 on UCSC Golden Path with GeneCards custom track

Promoters for ZBTB44 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZBTB44 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZBTB44 Gene

Chromosome:
11
Start:
130,226,677 bp from pter
End:
130,314,769 bp from pter
Size:
88,093 bases
Orientation:
Minus strand

Genomic View for ZBTB44 Gene

Genes around ZBTB44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZBTB44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZBTB44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB44 Gene

Proteins for ZBTB44 Gene

  • Protein details for ZBTB44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCP5-ZBT44_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 44
    Protein Accession:
    Q8NCP5
    Secondary Accessions:
    • Q6IPT8
    • Q86VJ7
    • Q86XX5

    Protein attributes for ZBTB44 Gene

    Size:
    570 amino acids
    Molecular mass:
    63848 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB44 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB44 Gene

Proteomics data for ZBTB44 Gene at MOPED

Post-translational modifications for ZBTB44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZBTB44 Gene

Domains & Families for ZBTB44 Gene

Gene Families for ZBTB44 Gene

Protein Domains for ZBTB44 Gene

Suggested Antigen Peptide Sequences for ZBTB44 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NCP5

UniProtKB/Swiss-Prot:

ZBT44_HUMAN :
  • Contains 1 BTB (POZ) domain.
  • Contains 4 C2H2-type zinc fingers.
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB44: view

Function for ZBTB44 Gene

Molecular function for ZBTB44 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZBTB44 Gene

genes like me logo Genes that share phenotypes with ZBTB44: view

Animal Model Products

miRNA for ZBTB44 Gene

miRTarBase miRNAs that target ZBTB44

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZBTB44 Gene

Localization for ZBTB44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB44 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB44 Gene COMPARTMENTS Subcellular localization image for ZBTB44 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZBTB44 Gene

Pathways & Interactions for ZBTB44 Gene

SuperPathways for ZBTB44 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB44 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZBTB44 Gene

Drugs & Compounds for ZBTB44 Gene

No Compound Related Data Available

Transcripts for ZBTB44 Gene

Unigene Clusters for ZBTB44 Gene

Zinc finger and BTB domain containing 44:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB44 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b
SP1: - - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - - - - -
SP7: - -
SP8:
SP9: -

Relevant External Links for ZBTB44 Gene

GeneLoc Exon Structure for
ZBTB44
ECgene alternative splicing isoforms for
ZBTB44

Expression for ZBTB44 Gene

mRNA expression in normal human tissues for ZBTB44 Gene

Protein differential expression in normal tissues from HIPED for ZBTB44 Gene

This gene is overexpressed in Plasma (45.3) and Peripheral blood mononuclear cells (21.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZBTB44 Gene



SOURCE GeneReport for Unigene cluster for ZBTB44 Gene Hs.721470

genes like me logo Genes that share expression patterns with ZBTB44: view

Protein tissue co-expression partners for ZBTB44 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB44 Gene

Orthologs for ZBTB44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB44 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZBTB44 35
  • 93.7 (n)
  • 96.89 (a)
ZBTB44 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB44 35
  • 94.22 (n)
  • 98.44 (a)
ZBTB44 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb44 35
  • 91.83 (n)
  • 96.47 (a)
Zbtb44 16
Zbtb44 36
  • 96 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZBTB44 35
  • 99.63 (n)
  • 100 (a)
ZBTB44 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb44 35
  • 91.39 (n)
  • 96.69 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 91 (a)
OneToMany
-- 36
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB44 36
  • 93 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZBTB44 35
  • 83.48 (n)
  • 92.22 (a)
ZBTB44 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZBTB44 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16848 35
zbtb44 35
  • 77.9 (n)
  • 88.62 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15152 35
zebrafish
(Danio rerio)
Actinopterygii zbtb44 35
  • 65.08 (n)
  • 69.91 (a)
zbtb44 36
  • 52 (a)
OneToOne
Species with no ortholog for ZBTB44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB44 Gene

ENSEMBL:
Gene Tree for ZBTB44 (if available)
TreeFam:
Gene Tree for ZBTB44 (if available)

Paralogs for ZBTB44 Gene

Paralogs for ZBTB44 Gene

Pseudogenes.org Pseudogenes for ZBTB44 Gene

genes like me logo Genes that share paralogs with ZBTB44: view

Variants for ZBTB44 Gene

Sequence variations from dbSNP and Humsavar for ZBTB44 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs17857365 - 130,261,321(+) GCTTT(C/T)GCGCT nc-transcript-variant, reference, missense
rs519024 -- 130,262,441(+) gccTG(G/T)GAACC intron-variant
rs551961 -- 130,246,916(+) acaaa(C/T)atacc intron-variant
rs564556 -- 130,240,328(+) AGCCA(A/C)CGCAC intron-variant
rs577742 -- 130,244,547(+) ctgta(A/G)tccca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZBTB44 Gene

Variant ID Type Subtype PubMed ID
nsv832295 CNV Gain 17160897
essv12346 CNV CNV 17122850
dgv446e1 CNV Complex 17122850
nsv468896 CNV Loss 19166990
esv33203 CNV Loss 17666407
nsv39016 CNV Loss 16902084
nsv818872 CNV Loss 17921354
essv506 CNV CNV 17122850
esv34550 CNV Loss 17911159

Variation tolerance for ZBTB44 Gene

Residual Variation Intolerance Score: 29.8% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZBTB44 Gene

HapMap Linkage Disequilibrium report
ZBTB44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB44 Gene

Disorders for ZBTB44 Gene

Relevant External Links for ZBTB44

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZBTB44

No disorders were found for ZBTB44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZBTB44 Gene

Publications for ZBTB44 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZBTB44 Gene

Sources for ZBTB44 Gene

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