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Aliases for ZBTB44 Gene

Aliases for ZBTB44 Gene

  • Zinc Finger And BTB Domain Containing 44 2 3
  • BTB/POZ Domain-Containing Protein 15 3 4
  • BTB (POZ) Domain Containing 15 2 3
  • Zinc Finger Protein 851 3 4
  • BTBD15 3 4
  • ZNF851 3 4
  • Zinc Finger And BTB Domain-Containing Protein 44 3
  • HSPC063 3

External Ids for ZBTB44 Gene

Previous Symbols for ZBTB44 Gene

  • BTBD15

Summaries for ZBTB44 Gene

GeneCards Summary for ZBTB44 Gene

ZBTB44 (Zinc Finger And BTB Domain Containing 44) is a Protein Coding gene. An important paralog of this gene is ENSG00000254553.

UniProtKB/Swiss-Prot for ZBTB44 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB44 Gene

Genomics for ZBTB44 Gene

Genomic Location for ZBTB44 Gene

Start:
130,226,677 bp from pter
End:
130,314,766 bp from pter
Size:
88,090 bases
Orientation:
Minus strand

Genomic View for ZBTB44 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB44 Gene

Regulatory Elements for ZBTB44 Gene

Proteins for ZBTB44 Gene

  • Protein details for ZBTB44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCP5-ZBT44_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 44
    Protein Accession:
    Q8NCP5
    Secondary Accessions:
    • Q6IPT8
    • Q86VJ7
    • Q86XX5

    Protein attributes for ZBTB44 Gene

    Size:
    570 amino acids
    Molecular mass:
    63848 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB44 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB44 Gene

Proteomics data for ZBTB44 Gene at MOPED

Post-translational modifications for ZBTB44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZBTB44 Gene

Domains for ZBTB44 Gene

Gene Families for ZBTB44 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type
  • BTBD :BTB/POZ domain containing

Protein Domains for ZBTB44 Gene

UniProtKB/Swiss-Prot:

ZBT44_HUMAN
Domain:
  • Contains 1 BTB (POZ) domain.:
    • Q8NCP5
Similarity:
  • Contains 4 C2H2-type zinc fingers.:
    • Q8NCP5
genes like me logo Genes that share domains with ZBTB44: view

Function for ZBTB44 Gene

Molecular function for ZBTB44 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZBTB44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB44: view

miRNA for ZBTB44 Gene

miRTarBase miRNAs that target ZBTB44

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB44 Gene

Localization for ZBTB44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB44 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB44 Gene COMPARTMENTS Subcellular localization image for ZBTB44 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZBTB44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB44: view

Pathways for ZBTB44 Gene

SuperPathways for ZBTB44 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB44: view

No data available for Pathways by source for ZBTB44 Gene

Transcripts for ZBTB44 Gene

Unigene Clusters for ZBTB44 Gene

Zinc finger and BTB domain containing 44:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB44 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b
SP1: - - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - - - - -
SP7: - -
SP8:
SP9: -

Relevant External Links for ZBTB44 Gene

GeneLoc Exon Structure for
ZBTB44
ECgene alternative splicing isoforms for
ZBTB44

Expression for ZBTB44 Gene

mRNA expression in normal human tissues for ZBTB44 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZBTB44 Gene

SOURCE GeneReport for Unigene cluster for ZBTB44 Gene Hs.721470

genes like me logo Genes that share expressions with ZBTB44: view

Orthologs for ZBTB44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB44 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB44 36
  • 99.63 (n)
  • 100 (a)
ZBTB44 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB44 36
  • 93.7 (n)
  • 96.89 (a)
ZBTB44 37
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB44 36
  • 94.22 (n)
  • 98.44 (a)
ZBTB44 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb44 36
  • 91.83 (n)
  • 96.47 (a)
Zbtb44 16
Zbtb44 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 91 (a)
OneToMany
-- 37
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB44 37
  • 93 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb44 36
  • 91.39 (n)
  • 96.69 (a)
chicken
(Gallus gallus)
Aves ZBTB44 36
  • 83.48 (n)
  • 92.22 (a)
ZBTB44 37
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZBTB44 37
  • 66 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15152 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16848 36
zbtb44 36
  • 77.9 (n)
  • 88.62 (a)
zebrafish
(Danio rerio)
Actinopterygii zbtb44 36
  • 65.08 (n)
  • 69.91 (a)
zbtb44 37
  • 52 (a)
OneToOne
Species with no ortholog for ZBTB44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB44 Gene

ENSEMBL:
Gene Tree for ZBTB44 (if available)
TreeFam:
Gene Tree for ZBTB44 (if available)

Paralogs for ZBTB44 Gene

Pseudogenes.org Pseudogenes for ZBTB44 Gene

genes like me logo Genes that share paralogs with ZBTB44: view

Variants for ZBTB44 Gene

Sequence variations from dbSNP and Humsavar for ZBTB44 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs197199 -- 130,307,960(+) acctt(A/C)ggtga intron-variant
rs265303 -- 130,309,530(+) TCACA(C/T)ATCCA intron-variant
rs471986 -- 130,228,472(+) AAAAT(C/T)GCCTA utr-variant-3-prime, nc-transcript-variant
rs478106 -- 130,248,614(+) ccagc(C/T)tgagc intron-variant
rs495197 -- 130,264,892(+) accag(C/T)ttgtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZBTB44 Gene

Variant ID Type Subtype PubMed ID
nsv832295 CNV Gain 17160897
essv12346 CNV CNV 17122850
dgv446e1 CNV Complex 17122850
nsv468896 CNV Loss 19166990
esv33203 CNV Loss 17666407
nsv39016 CNV Loss 16902084
nsv818872 CNV Loss 17921354
essv506 CNV CNV 17122850
esv34550 CNV Loss 17911159

Relevant External Links for ZBTB44 Gene

HapMap Linkage Disequilibrium report
ZBTB44

Disorders for ZBTB44 Gene

No disorders were found for ZBTB44 Gene.

No data available for UniProtKB/Swiss-Prot for ZBTB44 Gene

Publications for ZBTB44 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PMID: 17525332) Matsuoka S. … Elledge S.J. (Science 2007) 4
  5. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 4

Products for ZBTB44 Gene

Sources for ZBTB44 Gene

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