ZBTB41 Gene
protein-coding GIFtS: 45
GCID: GC01M197122
|
|
zinc finger and BTB domain containing 41
| |
Aliases
for ZBTB41 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And BTB Domain Containing 411 2 | | FLJ361991 | | FRBZ11 2 3 | | RP11-469L3.12 | | ZNF9241 2 | | FRBZ1 Protein (FRBZ1)2 | | DKFZp686C061201 | | Zinc Finger And BTB Domain-Containing Protein 412 |
Export aliases for ZBTB41 gene to outside databasesPrevious GC identifers: GC01M193860 GC01M195389 GC01M168280 |
Summaries
for ZBTB41 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZBT41_HUMAN, Q5SVQ8Function: May be involved in transcriptional regulation
|
Genomic Views
for ZBTB41 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZBTB41 gene promoter:
RFX1 GATA-3 FOXO3 FOXO3b GATA-1 GATA-2 HFH-1 FOXO3a Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZBTB41
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB41 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q31.3 Ensembl cytogenetic band: 1q31.3 HGNC cytogenetic band: 1q31.3ZBTB41 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M197122: view genomic region
(about GC identifiers)
Start:
|
197,122,814 bp from pter |
End:
|
197,169,672 bp from pter |
Size:
|
46,859 bases |
Orientation:
|
minus strand |
|
Proteins
for ZBTB41 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZBT41_HUMAN, Q5SVQ8 (See
protein sequence)Recommended Name: Zinc finger and BTB domain-containing protein 41 Size: 909 amino acids; 105192 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A2RUA8 Q6MZT8 Q6ZR25 Q7Z4T1 Q8IZ99Alternative splicing: 2 isoforms: Q5SVQ8-1 Q5SVQ8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZBTB41: NX_Q5SVQ8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5SVQ8
ZBTB41 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_919290.2
ENSEMBL proteins: ENSP00000356375
Human Recombinant Protein Products for ZBTB41:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZBTB41 for ontologies About GeneDecksing
ZBTB41 Antibody Products:
Assay Products for ZBTB41: |
Protein
Domains /
Families
for ZBTB41 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZBTB41 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q5SVQ8ProtoNet protein and cluster: Q5SVQ8 1 Blocks protein family: IPB000210 BTB/POZ domain
UniProtKB/Swiss-Prot: ZBT41_HUMAN, Q5SVQ8Similarity: Contains 1 BTB (POZ) domainSimilarity: Contains 14 C2H2-type zinc fingers |
Function
for ZBTB41 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZBT41_HUMAN, Q5SVQ8Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZBTB41 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ZBTB41:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZBTB41 (NM_194314) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB41 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB41 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB41 |
|
Pathways & Interactions
for ZBTB41 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZBTB41
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZBTB41 (ENSP000003563754) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZBTB41 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZBTB41 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZBTB41
Search CenterWatch for drugs/clinical trials and news about ZBTB41 / ZBT41
|
Transcripts
for ZBTB41 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZBTB41 gene: NM_194314.2 Unigene Cluster for ZBTB41: Zinc finger and BTB domain containing 41 Hs.529439 [show with all ESTs]Unigene Representative Sequence: NM_1943142 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000467322(uc001gtx.1 uc009wyz.1) ENST00000367405
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZBTB41 (NM_194314) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZBTB41 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB41 |
Additional cDNA sequence: AK128549.1 AY163816.2 AY336933.1 BC043426.2 BC132818.1 BC136600.1 BX640886.1 3 DOTS entries: DT.99934663 DT.97816823 DT.95269698 24/68 AceView cDNA sequences (see all 68): AI678433 CB243844 BX955111 AY163816 T05514 AA862919 BM821756 BQ229719 AW771175 AI049654 AY336933 AI601230 BM477815 BG288830 CB959136 BM980815 AI018621 BM474036 AK128549 AW299558 BI918375 BU184154 BX640886 BX484282
GeneLoc Exon Structure
|
Expression
for ZBTB41 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZBTB41 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCAACTTG
About this image
See ZBTB41 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZBTB41
SOURCE GeneReport for Unigene cluster: Hs.529439
SABiosciences Custom PCR Arrays for ZBTB41
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB41
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZBTB41 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB41 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB41 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB41 |
Orthologs
for ZBTB41 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZBTB41 gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for ZBTB41 (if available)
TreeFam Gene Tree for ZBTB41 (if available) |
Paralogs
for ZBTB41 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZBTB41 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZBTB41 (197122814 - 197169672 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZBTB41
2 CNVs: 97605 3326
Human Gene Mutation Database (HGMD): ZBTB41
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBTB41 |
|
Disorders
/ Diseases
for ZBTB41 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZBTB41 for disorders About MalaCards
ZBTB41 for disorders About GeneDecksing
Export disorders for ZBTB41 gene to outside databases
|
Publications
for ZBTB41 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZBTB41 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZBTB41) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
|
External Searches for ZBTB41 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZBTB41 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZBTB41 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZBTB41 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZBTB41 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZBTB41 gene:
Search GeneIP for patents involving ZBTB41
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZBTB41 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZBTB41 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZBTB41 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZBTB41 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZBTB41 | | OriGene 3'-UTR Clone for ZBTB41 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZBTB41 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZBTB41 | | OriGene Custom Protein Services for ZBTB41 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZBTB41 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZBTB41 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZBTB41 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZBTB41 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZBTB41 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZBTB41 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZBTB41 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZBTB41 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB41 |
|  |  |  |  | | | | ThermoFisher Antibodies for ZBTB41 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB41 |
| |  | |
|
|
|
