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Aliases for ZBTB41 Gene

Aliases for ZBTB41 Gene

  • Zinc Finger And BTB Domain Containing 41 2 3
  • FRBZ1 3 4
  • Zinc Finger And BTB Domain-Containing Protein 41 3
  • FRBZ1 Protein (FRBZ1) 3
  • ZNF924 3

External Ids for ZBTB41 Gene

Previous GeneCards Identifiers for ZBTB41 Gene

  • GC01M193860
  • GC01M195389
  • GC01M168280

Summaries for ZBTB41 Gene

GeneCards Summary for ZBTB41 Gene

ZBTB41 (Zinc Finger And BTB Domain Containing 41) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZBTB41 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB41 Gene

Genomics for ZBTB41 Gene

Regulatory Elements for ZBTB41 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZBTB41 Gene

Start:
197,153,680 bp from pter
End:
197,200,542 bp from pter
Size:
46,863 bases
Orientation:
Minus strand

Genomic View for ZBTB41 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB41 Gene

Proteins for ZBTB41 Gene

  • Protein details for ZBTB41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SVQ8-ZBT41_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 41
    Protein Accession:
    Q5SVQ8
    Secondary Accessions:
    • A2RUA8
    • Q6MZT8
    • Q6ZR25
    • Q7Z4T1
    • Q8IZ99

    Protein attributes for ZBTB41 Gene

    Size:
    909 amino acids
    Molecular mass:
    105192 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB41 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB41 Gene

Proteomics data for ZBTB41 Gene at MOPED

Post-translational modifications for ZBTB41 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB41 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB41 Gene

Domains for ZBTB41 Gene

Gene Families for ZBTB41 Gene

HGNC:
  • BTBD :BTB/POZ domain containing
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZBTB41 Gene

Graphical View of Domain Structure for InterPro Entry

Q5SVQ8

UniProtKB/Swiss-Prot:

ZBT41_HUMAN :
  • Q5SVQ8
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB41: view

Function for ZBTB41 Gene

Molecular function for ZBTB41 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB41: view

Phenotypes for ZBTB41 Gene

GenomeRNAi human phenotypes for ZBTB41:
genes like me logo Genes that share phenotypes with ZBTB41: view

Animal Model Products

CRISPR Products

miRNA for ZBTB41 Gene

miRTarBase miRNAs that target ZBTB41

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB41

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB41 Gene

Localization for ZBTB41 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB41 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB41 Gene COMPARTMENTS Subcellular localization image for ZBTB41 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZBTB41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB41: view

Pathways for ZBTB41 Gene

SuperPathways for ZBTB41 Gene

No Data Available

Interacting Proteins for ZBTB41 Gene

Gene Ontology (GO) - Biological Process for ZBTB41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB41: view

No data available for Pathways by source for ZBTB41 Gene

Transcripts for ZBTB41 Gene

mRNA/cDNA for ZBTB41 Gene

Unigene Clusters for ZBTB41 Gene

Zinc finger and BTB domain containing 41:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZBTB41

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZBTB41

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB41 Gene

No ASD Table

Relevant External Links for ZBTB41 Gene

GeneLoc Exon Structure for
ZBTB41
ECgene alternative splicing isoforms for
ZBTB41

Expression for ZBTB41 Gene

mRNA expression in normal human tissues for ZBTB41 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZBTB41 Gene

SOURCE GeneReport for Unigene cluster for ZBTB41 Gene Hs.529439

genes like me logo Genes that share expressions with ZBTB41: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB41 Gene

Orthologs for ZBTB41 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZBTB41 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB41 35
  • 99.74 (n)
  • 99.78 (a)
ZBTB41 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB41 35
  • 91.72 (n)
  • 96.64 (a)
ZBTB41 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB41 35
  • 93.58 (n)
  • 96.81 (a)
ZBTB41 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb41 35
  • 88.68 (n)
  • 93.94 (a)
Zbtb41 16
Zbtb41 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB41 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB41 36
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb41 35
  • 88.9 (n)
  • 94.49 (a)
chicken
(Gallus gallus)
Aves ZBTB41 35
  • 78.75 (n)
  • 83.31 (a)
ZBTB41 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZBTB41 36
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zbtb41 35
  • 67.7 (n)
  • 69.48 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC573743 35
  • 63.92 (n)
  • 64.12 (a)
ZBTB41 36
  • 61 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG12942 36
  • 10 (a)
OneToMany
CG30020 36
  • 8 (a)
OneToMany
CG7101 36
  • 28 (a)
OneToMany
Species with no ortholog for ZBTB41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB41 Gene

ENSEMBL:
Gene Tree for ZBTB41 (if available)
TreeFam:
Gene Tree for ZBTB41 (if available)

Paralogs for ZBTB41 Gene

Selected SIMAP similar genes for ZBTB41 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZBTB41: view

No data available for Paralogs for ZBTB41 Gene

Variants for ZBTB41 Gene

Sequence variations from dbSNP and Humsavar for ZBTB41 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1127661 -- 197,153,913(-) AGGAT(A/G)CTTTA utr-variant-3-prime
rs1415212 -- 197,188,764(+) AGGAA(A/T)AAAAG intron-variant
rs1415213 -- 197,188,864(+) GTCTA(A/T)AAATT intron-variant
rs1415215 -- 197,189,019(+) ATAGA(G/T)GCAAC intron-variant
rs1415217 -- 197,182,116(+) CAGTA(C/T)TTACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZBTB41 Gene

Variant ID Type Subtype PubMed ID
nsv528460 CNV Gain 19592680
esv743 CNV CNV 17122850
essv19099 CNV CNV 17122850
nsv873070 CNV Gain+Loss 21882294
dgv515n71 CNV Loss 21882294
esv2445525 CNV Deletion 19546169

Relevant External Links for ZBTB41 Gene

HapMap Linkage Disequilibrium report
ZBTB41
Human Gene Mutation Database (HGMD)
ZBTB41

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB41 Gene

Disorders for ZBTB41 Gene

Relevant External Links for ZBTB41

Genetic Association Database (GAD)
ZBTB41
genes like me logo Genes that share disorders with ZBTB41: view

No data available for UniProtKB/Swiss-Prot for ZBTB41 Gene

Publications for ZBTB41 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Ischemic stroke is associated with the ABO locus: the EuroCLOT study. (PMID: 23381943) Williams F.M. … . (Ann. Neurol. 2013) 3

Products for ZBTB41 Gene

Sources for ZBTB41 Gene

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