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Aliases & Descriptions for ZBTB4
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases KAISO-L1 1 , 2 , 3 KIAA1538 1 , 2 , 3 , 5 OTTHUMP00000135276 2
Descriptions KAISO-like zinc finger protein 1 2 , 3 zinc finger and BTB domain containing 4 2
Search outside databases for aliases for ZBTB4 genePrevious GC identifer: GC17M007563
Summaries for ZBTB4 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: ZBTB4_HUMAN, Q9P1Z0 Function : May be involved in transcriptional regulation
Genomic Location for ZBTB4
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the ZBTB4 gene Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.2 ZBTB4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M007303:
(about GC identifiers )
Start:
7,303,421 bp from pter
End:
7,328,241 bp from pter
Size:
24,821 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000017.9 NT_010718.15 Proteins for ZBTB4
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: ZBTB4_HUMAN, Q9P1Z0 (See
protein sequence )Recommended Name: Zinc finger and BTB domain-containing protein 4 Size : 1013 amino acids; 105114 Da
Subcellular location : Nucleus (Potential)
Secondary accessions : Q7Z697 Q86XJ4 Q8N4V8
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (2 alternative transcripts):
NP_001122305.1 NP_065950.2 ENSEMBL proteins: ENSP00000369973 ENSP00000307858 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for ZBTB4: Assays for ZBTB4:
Protein
Domains/ Families for ZBTB4(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9P1Z0 ProtoNet protein and cluster: Q9P1Z0
1 Blocks protein family : IPB000210 BTB/POZ domain UniProtKB/Swiss-Prot: ZBTB4_HUMAN, Q9P1Z0 Similarity : Contains 1 BTB (POZ) domainSimilarity : Contains 6 C2H2-type zinc fingers
Gene Function for ZBTB4
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_020899 Applied Biosystems Silencer ® siRNAs for ZBTB4 Sigma-Aldrich siRNA and siRNA Panels for ZBTB4 Sigma-Aldrich shRNA for ZBTB4 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_020899 UniProtKB/Swiss-Prot: ZBTB4_HUMAN, Q9P1Z0 Function : May be involved in transcriptional regulation
4 Gene Ontology (GO) molecular function terms (links to tree view) :
About this table
Pathways & Interactions for ZBTB4
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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Gene Network CentralTM Interacting Genes and Proteins Network for ZBTB4 1 Interacting protein for ZBTB4 (ENSP00000307858 3 ) via UniProtKB, MINT, and/or STRING About this table 2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0006350 transcription
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA --
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Drugs & Compounds for ZBTB4 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for ZBTB4
Transcripts for ZBTB4(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_020899 Sigma-Aldrich siRNA and siRNA Panels for ZBTB4 Sigma-Aldrich shRNA for ZBTB4 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001128833 NM_020899
REFSEQ mRNAs for ZBTB4 gene (2 alternative transcripts): NM_001128833.1 NM_020899.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001128833 NM_020899
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833                                  untagged cDNA clones in CMV expression vector (see all 2 ): NM_001128833  
Additional cDNA sequence: AB040971.2 AK027143.1 AK122826.1 AK122971.1 AY302699.1 BC015902.1 BC033259.1 BC043352.2 BC131774.1
10 DOTS entries : DT.100819620 DT.456393 DT.99957914 DT.91882042 DT.120976070 DT.304966 DT.75156238 DT.95195736 DT.95285201 DT.95305021
24/273 AceView cDNA sequences (see all 273
):CB306760 BM692980 AY302699 F28370 AI185028 AW991664 AA617772 BM697291 AI669498 AW468104 AA375608 BU620047 AA338527 BQ880799 AK122826 AA255479 BE218908 BC033259 W37794 BM908383 CA395952 AW794402 BE327655 AI191330
highest scoring ESTs for ZBTB4 :BC043352 BQ427479 W51743 AA037440 AA092171 AA150142 AA152211 AA255479 AA256903 AA284243
Unigene Cluster for ZBTB4: Zinc finger and BTB domain containing 4 Hs.35096 [show with all ESTs ] Unigene Representative Sequence: NM_020899 GeneLoc Exon Structure 2 Ensembl transcripts including schematic representations : ENST00000380599
ENST00000311403
Expression for ZBTB4
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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ZBTB4 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for ZBTB4 1 / 2 / 3
6 probe-sets matching ZBTB4 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TTCCCTGGGASOURCE GeneReport for Unigene cluster: Hs.35096
Orthologs for ZBTB4
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for ZBTB4 gene from 4 species
About this table Species with no ortholog for ZBTB4 ENSEMBL Gene Tree for ZBTB4 Paralogs for ZBTB4 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for ZBTB4 gene ZNF295 2 ZBTB38 2 ZFP161 2 ZBTB33 2 Pseudogenes 1 related pseudogene
SNPs/Variants for ZBTB4 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for ZBTB4 (up to first 250kb)
Disorders & Mutations for ZBTB4
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 612308
Medical News for ZBTB4 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for ZBTB4 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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9 PubMed articles for ZBTB4 gene :
Search for ZBTB4
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ZBTB4
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing ZBTB4
(According to HUGE )
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Specialized Databases showing ZBTB4 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for ZBTB4 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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