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ZBTB38 Gene

protein-coding   GIFtS: 50
GCID: GC03P141043

Zinc Finger And BTB Domain Containing 38

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger And BTB Domain Containing 381 2
CIBZ2
ZNF9212
Zinc Finger And BTB Domain-Containing Protein 382

External Ids:    HGNC: 266361   Entrez Gene: 2534612   Ensembl: ENSG000001773117   OMIM: 6122185   UniProtKB: Q8NAP33   

Export aliases for ZBTB38 gene to outside databases

Previous GC identifers: GC03P142628 GC03P142525 GC03P138418


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZBTB38 Gene:
The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded
protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein
has been associated with apoptosis in some cell types. (provided by RefSeq, Jun 2010)

GeneCards Summary for ZBTB38 Gene:
ZBTB38 (zinc finger and BTB domain containing 38) is a protein-coding gene. Diseases associated with ZBTB38 include prion disease, and kaposi's sarcoma. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZBTB21.

UniProtKB/Swiss-Prot: ZBT38_HUMAN, Q8NAP3
Function: Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late
postmitotic neurons (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZBTB38 gene promoter:
         SRF   SRF (504 AA)   Bach2   FOXO3   Lmo2   STAT5A   FOXO3b   MEF-2A   FOXO3a   aMEF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZBTB38

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZBTB38


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q23   Ensembl cytogenetic band:  3q23   HGNC cytogenetic band: 3q23

ZBTB38 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZBTB38 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P141043:  view genomic region     (about GC identifiers)

Start:
141,043,055 bp from pter      End:
141,168,634 bp from pter
Size:
125,580 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZBT38_HUMAN, Q8NAP3 (See protein sequence)
Recommended Name: Zinc finger and BTB domain-containing protein 38  
Size: 1195 amino acids; 134257 Da
Sequence caution: Sequence=BAC03868.1; Type=Frameshift; Positions=147;
Secondary accessions: D3DNF6

Explore the universe of human proteins at neXtProt for ZBTB38: NX_Q8NAP3

Explore proteomics data for ZBTB38 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZBTB38 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001073881.2  
    ENSEMBL proteins: 
     ENSP00000426931   ENSP00000421037   ENSP00000422051   ENSP00000426288   ENSP00000424254  
     ENSP00000426387   ENSP00000425705   ENSP00000422347   ENSP00000422757   ENSP00000406955  
     ENSP00000422081   ENSP00000422894   ENSP00000372635  

    ZBTB38 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZBTB38

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    Cloud-Clone Corp. CLIAs for ZBTB38


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR000210 BTB/POZ-like
     IPR015880 Znf_C2H2-like
     IPR011333 BTB/POZ_fold
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q8NAP3

    ProtoNet protein and cluster: Q8NAP3

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: ZBT38_HUMAN, Q8NAP3
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 10 C2H2-type zinc fingers


    ZBTB38 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZBT38_HUMAN, Q8NAP3
    Function: Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late
    postmitotic neurons (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ISS--
    GO:0005515protein binding IPI16354688
    GO:0008327methyl-CpG binding IDA16354688
         
    ZBTB38 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZBTB38
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    miRNA
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    miRTarBase miRNAs that target ZBTB38:
    hsa-mir-877-3p (MIRT037111), hsa-mir-26b-5p (MIRT030256), hsa-mir-877-5p (MIRT037337), hsa-mir-21-5p (MIRT031057), hsa-mir-30b-5p (MIRT023427)

    Block miRNA regulation of human, mouse, rat ZBTB38 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZBTB38 (see all 91):
    hsa-miR-361-5p hsa-miR-300 hsa-miR-374a hsa-miR-550a* hsa-miR-298 hsa-miR-3170 hsa-miR-200b hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZBTB38

    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB38


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZBT38_HUMAN, Q8NAP3: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0072562blood microparticle IDA--

    ZBTB38 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZBTB38
    Interactions:

        Search GeneGlobe Interaction Network for ZBTB38

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ZBTB38 (Q8NAP33 ENSP000003726354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBBP6Q7Z6E93, ENSP000003178724I2D: score=2 STRING: ENSP00000317872
    PPP1CAENSP000003260314STRING: ENSP00000326031
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0045892negative regulation of transcription, DNA-templated IDA16354688
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ISS--

    ZBTB38 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZBTB38 (ZBT38)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZBTB38 gene (2 alternative transcripts): 
    NM_001080412.2  NM_152535.1  

    Unigene Cluster for ZBTB38:

    Zinc finger and BTB domain containing 38
    Hs.518301  [show with all ESTs]
    Unigene Representative Sequence: NM_001080412
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000509842 ENST00000513619 ENST00000512276 ENST00000507657 ENST00000507722
    ENST00000512327 ENST00000513249 ENST00000503809 ENST00000513258 ENST00000506623
    ENST00000509883 ENST00000514251(uc003etw.3 uc010hun.3 uc010huo.3 uc003ety.3 uc010hup.3)
    ENST00000510338 ENST00000504673 ENST00000513570 ENST00000441582 ENST00000510726
    ENST00000509813
    miRNA
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    Block miRNA regulation of human, mouse, rat ZBTB38 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZBTB38 (see all 91):
    hsa-miR-361-5p hsa-miR-300 hsa-miR-374a hsa-miR-550a* hsa-miR-298 hsa-miR-3170 hsa-miR-200b hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZBTB38
    Predesigned siRNA for gene silencing in human, mouse, rat ZBTB38
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    OriGene clones in human, mouse for ZBTB38 (see all 6)
    OriGene ORF clones in mouse, rat for ZBTB38
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZBTB38 (NM_001080412)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZBTB38
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZBTB38
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZBTB38
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZBTB38
      QuantiTect SYBR Green Assays in human, mouse, rat ZBTB38
      QuantiFast Probe-based Assays in human, mouse, rat ZBTB38

    Additional mRNA sequence: 

    AK025985.1 AK055693.1 AK092355.1 AK094201.1 AK302568.1 AK307452.1 AK311479.1 AK311501.1 
    AL833148.1 BC008901.2 BC015444.1 BC022936.1 BC051734.1 BC072415.1 BC107745.1 

    12 DOTS entries:

    DT.455936  DT.100726896  DT.120898500  DT.100009025  DT.100811255  DT.120898448  DT.95253719  DT.120898403 
    DT.120898470  DT.102843102  DT.120898435  DT.95096094 

    Selected AceView cDNA sequences (see all 244):

    AK055693 AL833148 CD676777 AA480309 BM931073 AI742334 CA391052 AW024367 
    AA463731 BP363249 AI219217 BC008901 AI143149 CB178638 AW192379 AW070974 
    AI470490 R32881 AA353316 AI928164 BC022936 AK025985 AA258994 BM984007 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZBTB38 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAACTAGA
    ZBTB38 Expression
    About this image

    ZBTB38 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZBTB38 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.518301
        Custom PCR Arrays for ZBTB38
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZBTB38

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZBTB38 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zbtb381 , 5 zinc finger and BTB domain containing 381, 5 82.28(n)1
    81.7(a)1
      9 (50.71 cM)5
    2450071  NM_175537.31  NP_780746.21 
     966827635 
    chicken
    (Gallus gallus)
    Aves ZBTB381 zinc finger and BTB domain containing 38 68.64(n)
    65.48(a)
      424783  XM_004937066.1  XP_004937123.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZBTB386
    zinc finger and BTB domain containing 38
    56(a)
    1 ↔ 1
    3(22289238-22292768)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia zbtb381 zinc finger and BTB domain containing 38 56.84(n)
    50.28(a)
      100488939  XM_004917826.1  XP_004917883.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018821921 zinc finger and BTB domain-containing protein 38-like 50.84(n)
    44.11(a)
      101882192  XM_005159233.1  XP_005159290.1 


    ENSEMBL Gene Tree for ZBTB38 (if available)
    TreeFam Gene Tree for ZBTB38 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZBTB38 gene
    ZBTB212  ZBTB332  ZBTB142  ZBTB7C2  ZBTB7A2  ZBTB7B2  ZBTB42  
    Selected SIMAP similar genes for ZBTB38 using alignment to 13 protein entries:     ZBT38_HUMAN (see all proteins) (see all similar genes):
    KLHL36    ZNF295    ZBTB4    ZBTB21    ZBTB20    ZBTB7C
    ZBTB14    HIC1    BACH2    Bach2    KLHL2    KLHL32
    ZBTB45    PLZF    ZFS-5    ZNF410    MYNN    kr-znf3

    ZBTB38 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    ZBT38_HUMAN, Q8NAP3: Genetic variations in ZBTB38 define the stature quantitative trait locus 10 (STQTL10) [MIM:612221].
    Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a
    model trait for studying genetic influence on quantitative traits


    Selected SNPs for ZBTB38 (see all 2319)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs755278721,2
    C--138479535(+) GTGTGC/TGCGCG 1 -- int10--------
    rs109354291,2
    C--138495468(+) TTTTTT/-AAGAA 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1402747391,2
    --141017646(+) GTCCTA/GAAAAA 1 -- us2k10--------
    rs76426671,2
    C,F,A,H--141017650(+) TAAAAA/CATCTT 1 -- us2k18Minor allele frequency- C:0.13NS EA NA WA 666
    rs2018275721,2
    C--141017682(-) TTTTTG/TTCTTC 1 -- us2k10--------
    rs775174941,2
    C--141017809(+) CAAGGA/GACCTT 1 -- us2k10--------
    rs560541411,2
    C,F--141017843(+) TTTTAA/GTTAGT 1 -- us2k11Minor allele frequency- G:0.11NA 120
    rs559235281,2
    C--141017873(+) TTCCCA/GTTAGA 1 -- us2k10--------
    rs1179515301,2
    C,F--141018068(+) CATCAC/GTGCTA 1 -- us2k11Minor allele frequency- G:0.07EA 120
    rs1442247061,2
    --141018131(+) TGAGAG/TCCTGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZBTB38 (141043055 - 141168634 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZBTB38:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678380CNV Deletion23128226
    esv2673630CNV Deletion23128226
    esv2662025CNV Deletion23128226
    nsv829744CNV Loss17160897
    nsv460871CNV Loss19166990
    nsv819098CNV Loss19587683

    Human Gene Mutation Database (HGMD): ZBTB38
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZBTB38
    DNA2.0 Custom Variant and Variant Library Synthesis for ZBTB38

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612218    OMIM disorders: --

    7 diseases for ZBTB38:    
    About MalaCards
    prion disease    kaposi's sarcoma    crohn's disease    sarcoma
    prostate cancer    prostatitis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for ZBTB38:
    Kuru encephalopathy

    ZBTB38 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZBTB38
    Human Genome Epidemiology (HuGE) Navigator: ZBTB38 (8 documents)

    Export disorders for ZBTB38 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZBTB38 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with ZBTB38)
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    1. Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. (PubMed id 22210626)1, 4 Mead S....Collinge J. (Hum. Mol. Genet. 2012)
    2. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. (PubMed id 21998595)1, 4 N'Diaye A....Haiman C.A. (PLoS Genet. 2011)
    3. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. (PubMed id 21743467)1, 4 Kote-Jarai Z....TybjA ( 2011)
    4. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
    5. A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. (PubMed id 20189936)1, 4 Okada Y....Kamatani N. (Hum. Mol. Genet. 2010)
    6. Identification of 15 loci influencing height in a Korean population. (PubMed id 19893584)1, 4 Kim J.J....Lee J.K. (J. Hum. Genet. 2010)
    7. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. (PubMed id 20846217)1, 4 Lee J.J....Hirschhorn J. (Ann. Hum. Genet. 2010)
    8. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. (PubMed id 19396169)1, 4 Cho Y.S....Kim H.L. (Nat. Genet. 2009)
    9. Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. (PubMed id 19266077)1, 4 Sovio U....Jarvelin M.R. (PLoS Genet. 2009)
    10. Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. (PubMed id 19343178)1, 4 Soranzo N....Deloukas P. (PLoS Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 253461 HGNC: 26636 AceView: FLJ35036 Ensembl:ENSG00000177311 euGenes: HUgn253461
    ECgene: ZBTB38 H-InvDB: ZBTB38

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZBTB38 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZBTB38 gene:
    Search GeneIP for patents involving ZBTB38

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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