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Aliases for ZBTB37 Gene

Aliases for ZBTB37 Gene

  • Zinc Finger And BTB Domain Containing 37 2 3
  • Zinc Finger And BTB Domain-Containing Protein 37 3
  • D430004I08Rik 3
  • ZNF908 3

External Ids for ZBTB37 Gene

Summaries for ZBTB37 Gene

GeneCards Summary for ZBTB37 Gene

ZBTB37 (Zinc Finger And BTB Domain Containing 37) is a Protein Coding gene. An important paralog of this gene is NACC2.

UniProtKB/Swiss-Prot for ZBTB37 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB37 Gene

Genomics for ZBTB37 Gene

Genomic Location for ZBTB37 Gene

Start:
173,868,082 bp from pter
End:
173,903,549 bp from pter
Size:
35,468 bases
Orientation:
Plus strand

Genomic View for ZBTB37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB37 Gene

Regulatory Elements for ZBTB37 Gene

Proteins for ZBTB37 Gene

  • Protein details for ZBTB37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TC79-ZBT37_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 37
    Protein Accession:
    Q5TC79
    Secondary Accessions:
    • Q5TC80
    • Q96M87
    • Q9BQ88

    Protein attributes for ZBTB37 Gene

    Size:
    503 amino acids
    Molecular mass:
    56055 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZBTB37 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZBTB37 Gene

Proteomics data for ZBTB37 Gene at MOPED

Post-translational modifications for ZBTB37 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB37 Gene

No data available for DME Specific Peptides for ZBTB37 Gene

Domains for ZBTB37 Gene

Gene Families for ZBTB37 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type
  • BTBD :BTB/POZ domain containing

Protein Domains for ZBTB37 Gene

Suggested Antigen Peptide Sequences for ZBTB37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5TC79

UniProtKB/Swiss-Prot:

ZBT37_HUMAN
Domain:
  • Contains 1 BTB (POZ) domain.:
    • Q5TC79
Similarity:
  • Contains 3 C2H2-type zinc fingers.:
    • Q5TC79
genes like me logo Genes that share domains with ZBTB37: view

Function for ZBTB37 Gene

Molecular function for ZBTB37 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB37: view

Phenotypes for ZBTB37 Gene

GenomeRNAi human phenotypes for ZBTB37:
genes like me logo Genes that share phenotypes with ZBTB37: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZBTB37 Gene

Localization for ZBTB37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB37 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB37 Gene COMPARTMENTS Subcellular localization image for ZBTB37 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZBTB37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB37: view

Pathways for ZBTB37 Gene

SuperPathways for ZBTB37 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZBTB37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB37: view

No data available for Pathways by source for ZBTB37 Gene

Transcripts for ZBTB37 Gene

Unigene Clusters for ZBTB37 Gene

Zinc finger and BTB domain containing 37:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB37 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5
SP1: - -
SP2: -
SP3:
SP4:

Relevant External Links for ZBTB37 Gene

GeneLoc Exon Structure for
ZBTB37
ECgene alternative splicing isoforms for
ZBTB37

Expression for ZBTB37 Gene

mRNA expression in normal human tissues for ZBTB37 Gene

mRNA differential expression in normal tissues according to GTEx for ZBTB37 Gene

This gene is overexpressed in Testis (5.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZBTB37 Gene

SOURCE GeneReport for Unigene cluster for ZBTB37 Gene Hs.668497

genes like me logo Genes that share expressions with ZBTB37: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZBTB37 Gene

Orthologs for ZBTB37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB37 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB37 35
  • 99.8 (n)
  • 100 (a)
ZBTB37 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB37 35
  • 93.37 (n)
  • 97.61 (a)
ZBTB37 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB37 35
  • 93.84 (n)
  • 97.81 (a)
ZBTB37 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb37 35
  • 91.3 (n)
  • 95.22 (a)
Zbtb37 16
Zbtb37 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB37 36
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB37 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb37 35
  • 90.57 (n)
  • 95.42 (a)
chicken
(Gallus gallus)
Aves ZBTB37 35
  • 81.11 (n)
  • 93.24 (a)
ZBTB37 36
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZBTB37 36
  • 89 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC53639 35
tropical clawed frog
(Silurana tropicalis)
Amphibia zbtb37 35
  • 75.15 (n)
  • 85.69 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.16162 35
zbtb37 35
  • 69.36 (n)
  • 72.93 (a)
zbtb37 36
  • 69 (a)
OneToOne
Species with no ortholog for ZBTB37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB37 Gene

ENSEMBL:
Gene Tree for ZBTB37 (if available)
TreeFam:
Gene Tree for ZBTB37 (if available)

Paralogs for ZBTB37 Gene

genes like me logo Genes that share paralogs with ZBTB37: view

Variants for ZBTB37 Gene

Sequence variations from dbSNP and Humsavar for ZBTB37 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs941987 -- 173,871,661(-) ATAAC(A/G)CTTTT intron-variant, downstream-variant-500B
rs1001582 -- 173,883,591(-) AAACA(C/G)AATAA intron-variant
rs1064054 -- 173,887,404(+) TATCA(G/T)AAAAC utr-variant-3-prime
rs1322774 -- 173,870,102(+) TGAAA(C/T)TTTAC intron-variant
rs1322775 -- 173,886,160(+) CCCCT(A/T)TGAGC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZBTB37 Gene

Variant ID Type Subtype PubMed ID
nsv831926 CNV Gain+Loss 17160897
dgv149e1 CNV Complex 17122850

Relevant External Links for ZBTB37 Gene

HapMap Linkage Disequilibrium report
ZBTB37

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB37 Gene

Disorders for ZBTB37 Gene

Relevant External Links for ZBTB37

Genetic Association Database (GAD)
ZBTB37
Human Genome Epidemiology (HuGE) Navigator
ZBTB37
genes like me logo Genes that share disorders with ZBTB37: view

No data available for UniProtKB/Swiss-Prot for ZBTB37 Gene

Publications for ZBTB37 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 48

Products for ZBTB37 Gene

Sources for ZBTB37 Gene

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