Aliases for ZBTB32 Gene
External Ids for ZBTB32 Gene
Previous GeneCards Identifiers for ZBTB32 Gene
GeneCards Summary for ZBTB32 Gene
ZBTB32 (Zinc Finger And BTB Domain Containing 32) is a Protein Coding gene. Diseases associated with ZBTB32 include fanconi anemia, complementation group a and primary syphilis. Among its related pathways are Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template and DNA Double-Strand Break Repair. GO annotations related to this gene include nucleic acid binding and transcription corepressor activity. An important paralog of this gene is ZBTB39.
UniProtKB/Swiss-Prot for ZBTB32 Gene
DNA-binding protein that binds to the to a 5-TGTACAGTGT-3 core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).