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Aliases for ZBTB3 Gene

Aliases for ZBTB3 Gene

  • Zinc Finger And BTB Domain Containing 3 2 3
  • ZBTB33 6
  • KAISO 6

External Ids for ZBTB3 Gene

Previous GeneCards Identifiers for ZBTB3 Gene

  • GC11M062766
  • GC11M062293
  • GC11M062275
  • GC11M061931
  • GC11M062518
  • GC11M058847

Summaries for ZBTB3 Gene

GeneCards Summary for ZBTB3 Gene

ZBTB3 (Zinc Finger And BTB Domain Containing 3) is a Protein Coding gene. Diseases associated with ZBTB3 include colorectal cancer. Among its related pathways are Wnt Signaling Pathway (WikiPathways). An important paralog of this gene is ENSG00000254553.

UniProtKB/Swiss-Prot for ZBTB3 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZBTB3 Gene

Genomics for ZBTB3 Gene

Regulatory Elements for ZBTB3 Gene

Genomic Location for ZBTB3 Gene

Start:
62,748,319 bp from pter
End:
62,754,188 bp from pter
Size:
5,870 bases
Orientation:
Minus strand

Genomic View for ZBTB3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZBTB3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZBTB3 Gene

Proteins for ZBTB3 Gene

  • Protein details for ZBTB3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H5J0-ZBTB3_HUMAN
    Recommended name:
    Zinc finger and BTB domain-containing protein 3
    Protein Accession:
    Q9H5J0
    Secondary Accessions:

    Protein attributes for ZBTB3 Gene

    Size:
    574 amino acids
    Molecular mass:
    61827 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZBTB3 Gene

Proteomics data for ZBTB3 Gene at MOPED

Post-translational modifications for ZBTB3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZBTB3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZBTB3 Gene

Domains for ZBTB3 Gene

Gene Families for ZBTB3 Gene

HGNC:
  • BTBD :BTB/POZ domain containing
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZBTB3 Gene

Suggested Antigen Peptide Sequences for ZBTB3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H5J0

UniProtKB/Swiss-Prot:

ZBTB3_HUMAN :
  • Q9H5J0
Domain:
  • Contains 1 BTB (POZ) domain.
Similarity:
  • Contains 2 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZBTB3: view

Function for ZBTB3 Gene

Molecular function for ZBTB3 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZBTB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZBTB3: view

Phenotypes for ZBTB3 Gene

GenomeRNAi human phenotypes for ZBTB3:
genes like me logo Genes that share phenotypes with ZBTB3: view

miRNA for ZBTB3 Gene

miRTarBase miRNAs that target ZBTB3

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZBTB3 Gene

Localization for ZBTB3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZBTB3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZBTB3 Gene COMPARTMENTS Subcellular localization image for ZBTB3 gene
Compartment Confidence
nucleus 3
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZBTB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZBTB3: view

Pathways for ZBTB3 Gene

genes like me logo Genes that share pathways with ZBTB3: view

Pathways by source for ZBTB3 Gene

1 BioSystems pathway for ZBTB3 Gene

Gene Ontology (GO) - Biological Process for ZBTB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZBTB3: view

Transcripts for ZBTB3 Gene

mRNA/cDNA for ZBTB3 Gene

(15) Selected AceView cDNA sequences:
(1) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZBTB3 Gene

Zinc finger and BTB domain containing 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZBTB3 Gene

No ASD Table

Relevant External Links for ZBTB3 Gene

GeneLoc Exon Structure for
ZBTB3
ECgene alternative splicing isoforms for
ZBTB3

Expression for ZBTB3 Gene

mRNA expression in normal human tissues for ZBTB3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZBTB3 Gene

SOURCE GeneReport for Unigene cluster for ZBTB3 Gene Hs.147554

genes like me logo Genes that share expressions with ZBTB3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZBTB3 Gene

Orthologs for ZBTB3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZBTB3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZBTB3 35
  • 99.42 (n)
  • 99.48 (a)
ZBTB3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZBTB3 35
  • 89.06 (n)
  • 88.93 (a)
ZBTB3 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZBTB3 35
  • 88.56 (n)
  • 87.91 (a)
ZBTB3 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zbtb3 35
  • 86.63 (n)
  • 84.5 (a)
Zbtb3 16
Zbtb3 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZBTB3 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZBTB3 36
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zbtb3 35
  • 86.54 (n)
  • 84.85 (a)
zebrafish
(Danio rerio)
Actinopterygii FP074862.4 36
  • 40 (a)
OneToMany
LOC100536022 35
  • 54.06 (n)
  • 48.26 (a)
zbtb3 36
  • 37 (a)
OneToMany
Species with no ortholog for ZBTB3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZBTB3 Gene

ENSEMBL:
Gene Tree for ZBTB3 (if available)
TreeFam:
Gene Tree for ZBTB3 (if available)

Paralogs for ZBTB3 Gene

genes like me logo Genes that share paralogs with ZBTB3: view

Variants for ZBTB3 Gene

Sequence variations from dbSNP and Humsavar for ZBTB3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs491333 -- 62,752,221(-) GCAGC(A/C)AACCA reference, missense
rs491634 -- 62,755,940(-) catgt(G/T)ggtca upstream-variant-2KB
rs493774 -- 62,755,864(-) CAGGC(A/G)TGAGC upstream-variant-2KB
rs543929 -- 62,751,466(+) gggcg(C/T)ggtgg utr-variant-3-prime
rs544641 - 62,752,093(-) AACAT(C/G)TAAGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZBTB3 Gene

Variant ID Type Subtype PubMed ID
nsv897623 CNV Loss 21882294
nsv348 CNV Loss 18451855
nsv483055 CNV Loss 15286789

Relevant External Links for ZBTB3 Gene

HapMap Linkage Disequilibrium report
ZBTB3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZBTB3 Gene

Disorders for ZBTB3 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for ZBTB3 Gene including...

Search for ZBTB3 Gene in MalaCards »
genes like me logo Genes that share disorders with ZBTB3: view

No data available for UniProtKB/Swiss-Prot for ZBTB3 Gene

Publications for ZBTB3 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZBTB3 Gene

Sources for ZBTB3 Gene

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